Pathology of Red Blood Cells in Patients with SARS-CoV-2 by Sona Hakobyan, Lina Hakobyan, Liana Abroyan, Aida Avetisyan, Hranush Avagyan, Nane Bayramyan, Lyudmila Niazyan, Mher Davidyants, Knarik Sargsyan, Tehmine Ghalechyan, Anna Semerjyan, Elena Karalova, Zaven Karalyan

“…<b>Conclusions:</b> Elevated serum ferritin, CRP levels, anisocytosis, and altered hemoglobin absorption at 420 nm wavelength are associated with adverse outcomes in SARS-CoV-2 infection. …”
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Biomarkers troponin and procalcitonin in addition to CRB-65 enhance risk stratification in patients with community-acquired pneumonia by Imrana Farhat, Maciej Rosolowski, Katharina Ahrens, Jasmin Lienau, Peter Ahnert, Mathias Pletz, Gernot Rohde, Jan Rupp, Markus Scholz, Martin Witzenrath, the CAPNETZ Study Group

“…We utilised a machine-learning approach on 800 samples from the German CAPNETZ network (competence network for CAP) to refine risk prediction models combining these biomarkers with the CRB-65 score regarding our defined end-point: death or ICU admission during the current CAP episode within 28 days after study inclusion. Results Elevated levels of biomarkers were associated with the end-point. …”
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Second order slip micropolar MHD hybrid nanofluid flow over a stretching surface with uniform heat source and activation energy: Numerical computational approach by Syed Arshad Abas, Hakeem Ullah, Mehreen Fiza, Ali Akgul, Aasim Ullah Jan, Magda Abd El-Rahman, Seham M. Al-Mekhlafi

“…Additionally, an increased volume fraction of nanoparticles elevates the heat transfer rate by 6.3 % while diminishing the Sherwood number by 2.6 %, showcasing the thermal enhancement capabilities of the hybrid nanofluid. …”
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Isolation of competent actinomycetes strains from soil planted with three species of mint irrigated with olive mill wastewater by Oumaima Beroigui, Lahsen El Ghadraoui, Faouzi Errachidi

“…Results: Analysis revealed that OMWW contained high levels of organic matter and mineral salts, resulting in elevated chemical oxygen demand and salinity. Application of OMWW at a dose of 5 L/m² enhanced soil microflora, but this effect diminished beyond this dose, except for actinomycetes, which remained resilient even at 10L/m². …”
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FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression by Sama Rezasoltani, Elahe Shams, Moein Piroozkhah, Yaser Aidi, Mehdi Azizmohammad Looha, Parmida Bagheri, Roudabeh Behzadi Andouhjerdi, Amir Sadeghi, Leili Rejali, Ehsan Nazemalhosseini-Mojarad

“…Subsequently, the mRNA, miRNA, and lncRNA expression levels were examined in intestinal biopsy specimens from 30 healthy controls, 30 Adenoma patients, and 30 cases of CRC stage I using qRT-PCR. Results Elevated expression levels of FadA, ANXA2, hsa-let-7a-2, and LINC00460 were observed in CRC specimens, followed by AP cases, in comparison to samples from normal individuals. …”
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Impact of Acute Myocardial Injury on Short‐ and Long‐Term Outcomes in Patients With Primary Intracerebral Hemorrhage by Shenghui Ma, Jiawen Li, Qi Kong, Zhiming Xu, Haojie Wu, Yujia Jin, Xianghua Ye, Dong Luo, Lusha Tong, Feng Gao

“…AMI was defined as an elevated cTn above the upper‐reference limit (14 ng/L) along with a rise/fall >20%. …”
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Heat Tolerance Differences Between Hu Sheep and Hu Crossbred Sheep in Microbial Community Structure and Metabolism by Jing-Da Yuan, Li-Wei Wang, Shao-Yin Fu, Ri-Ge-Li-Tu E, Xiao-Qi Ren, Hua Sun, Fang Liu, Biao Wang, Jiang-Hong An, Meng-Ran Zhao, Jiang-Feng He, Xiao-Long He

“…Metabolomic results showed that, compared to Hu sheep, Xinggao sheep exhibited higher cortisol (COR) and dopamine (DA) levels under heat stress conditions, a stronger lipid mobilization capacity, and elevated levels of tricarboxylic acid (TCA) cycle-related metabolites. …”
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The impact of drought on forest spring phenology in northern China by Haowen Hu, Pengcheng Xue, Shaodong Huang, Zong Wang, Nina Xiong, Liang Shi, Boyi Liang, Jia Wang

“…In humid region, drought causes an advance in the SOS for most areas, whereas in semi-arid region, the forests experience a pronounced delay in SOS due to drought conditions. (3) We further explored the different impact patterns of spring phenology during drought years across various hydroclimatic regions: in humid regions during dry years, SOS is primarily driven by elevated temperatures; conversely, in arid and semi-arid regions, SOS is predominantly influenced by water deficiency resulting from drought conditions. …”
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Constraints on triggered seismicity and its control on permeability evolution by Derek Elsworth, Ziyan Li, Pengliang Yu, Mengke An, Fengshou Zhang, Rui Huang, Zihan Sun, Guanglei Cui, Tianyu Chen, Quan Gan, Yixin Zhao, Jishan Liu, Shimin Liu

“…Importantly, we quantify for the first time the role of prestress in defining the elevated magnitude and seismic moment of fluid injection-triggered events, and demonstrate that such MEQs can also be used as diagnostic in quantifying permeability evolution in the crust.…”
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Potential implications of granzyme B in keloids and hypertrophic scars through extracellular matrix remodeling and latent TGF-β activation by Alexandre Aubert, Alexandre Aubert, Alexandre Aubert, Jenna Goeres, Jenna Goeres, Jenna Goeres, Amy Liu, Amy Liu, Amy Liu, Martin Kao, Martin Kao, Martin Kao, Katlyn C. Richardson, Katlyn C. Richardson, Katlyn C. Richardson, Karen Jung, Karen Jung, Karen Jung, Boris Hinz, Boris Hinz, Richard I. Crawford, Richard I. Crawford, David J. Granville, David J. Granville, David J. Granville

“…Increased GzmB-positive mast cells were identified in the dermis of KS and HS but not healthy skin controls. Elevated levels of substance P, a neuropeptide involved in mast cell degranulation, suggest that GzmB is released extracellularly, as confirmed by the significant reduction of the established extracellular GzmB substrate decorin in KS and HS. …”
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High-altitude hypoxia aggravated neurological deficits in mice induced by traumatic brain injury via BACH1 mediating astrocytic ferroptosis by Peng Zou, Tianjing Li, Zixuan Cao, Erwan Yang, Mingdong Bao, Haofuzi Zhang, Zhuoyuan Zhang, Dan Liu, Min Zhang, Xiangyu Gao, Junmiao Ge, Xiaofan Jiang, Zhicheng Tian, Peng Luo

“…In order to deeply investigate this scientific issue, we constructed a high-altitude hypoxic TBI model at different altitudes and used animal behavioral assessments (Modified neurological severity score, rotarod test, elevated plus maze test) as well as histopathological analyses (brain gross specimens, brain water content, Evans blue content, hypoxia inducible factor-1α, Hematoxylin-Eosin staining and ROS detection) to reveal its underlying principles and characteristics. …”
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Triglyceride to high density lipoprotein cholesterol ratio and major adverse cardiovascular events in ACS patients undergoing PCI by Shangxun Zhou, Miaohan Qiu, Kexin Wang, Jing Li, Yi Li, Yaling Han

“…A higher baseline TG/HDL-C ratio was associated with an elevated risk of MACE but a reduced risk of bleeding events in ACS patients undergoing PCI.…”
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The clinical significance of T cell infiltration and immune checkpoint expression in central nervous system germ cell tumors by Jiajun Zhou, Jiajun Zhou, Wenhao An, Lei Guan, Lei Guan, Jinyu Shi, Qiaozhen Qin, Shuai Zhong, Zheng Huang, Rui Liu, Chenxing Wu, Zhong Ma, Xueling Qi, Xiaoxia Jiang, Yan Wang, Shouwei Li

“…Additionally, CTLA-4 expression was detected in 58.06% of cases, while PD-1 and PD-L1 were expressed in over 90%, with higher CTLA-4 levels in germinomas and elevated PD-L1 levels in NGGCTs. T cell infiltration was positively correlated with immune checkpoint expression, particularly in germinomas. …”
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Clinical and biochemical characteristics for patients with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome: a pilot observational study by Pei Li, Ye Zhang, Li-Min Luo, Wen-Qing Wang, Jing Li, Yan Cheng, Xiao Dang, Yang Chen, Wei Jiang

“…Most patients suffered with hyperpigmentation (n = 18), organomegaly (n = 18), elevated vascular endothelial growth factor (VEGF) (n = 17), extravascular volume overload (n = 15), sclerotic bone lesions (n = 11), and hypothyroidism (n = 10). …”
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Peripheral blood age-sensitive immune markers in multiple sclerosis: relation to sex, cytomegalovirus status, and treatmentResearch in context by Haritha Desu, Renaud Balthazard, Audrey Daigneault, Sandra Da Cal, Wendy Klément, Jennifer Yu, Marie-Laure Clénet, Clara Margarido, Annie Levert, Canisius Fantodji, Olivier Tastet, Jean-Marc Girard, Pierre Duquette, Alexandre Prat, Gabrielle Macaron, Marie-Claude Rousseau, Nathalie Arbour, Catherine Larochelle

“…IL-4 and β-NGF levels were lower in untreated PwMS compared to controls, while EGF and bFGF levels were influenced by age and markedly elevated in PwMS in multivariable analysis. Samples from treated PwMS, but not untreated PwMS, showed lower levels of BDNF and TNF than controls. …”
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Effect of antiretroviral therapy on the mortality of HIV-1 infection long-term non-progressors: a cohort study by Jinming Su, Jie Liu, Fengxiang Qin, Rongfeng Chen, Tongxue Qin, Xing Tao, Xiu Chen, Wen Hong, Bingyu Liang, Ping Cui, Li Ye, Junjun Jiang, Hao Liang

“…The mortality risk was also elevated in the ART-naïve group versus the ART-experienced ones (aHR = 3.943, 95%CI: 2.658–5.850, P < 0.001). …”
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The necessity of gestational vitamin D supplementation depends on ambient temperature: concern for infant vitamin D status by Wanjun Yin, Wanjun Yin, Wanjun Yin, Wanjun Yin, Lei Zhang, Lei Zhang, Peng Zhu, Peng Zhu

“…In contrast, for maternal exposure to ambient temperature of &lt;10°C, maternal vitamin D supplementation was significantly associated with elevated 25(OH)D concentrations in cord blood.ConclusionGestational ambient temperature may be an ideal predictor for infant vitamin D status screening. …”
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Comparative Study on Associations Between Lung Cancer Prognosis and Diagnostic Criteria Set by the European Palliative Care Research Collaboration and the Asian Working Group for C... by Utae Katsushima, Takuya Fukushima, Jiro Nakano, Naoya Ogushi, Kazuki Fujii, Yutaro Nagata, Keisuke Kamisako, Yukiko Okuno, Yuta Okazaki, Kentaro Nakanishi, Kiyori Yoshida, Tatsuki Ikoma, Yuki Takeyasu, Yuta Yamanaka, Hiroshige Yoshioka, Kimitaka Hase, Takayasu Kurata

“…Among CRP, anorexia, and grip strength, elevated CRP may be the most prognostically relevant parameter in the AWGC criteria.…”
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Classifying problematic gaming using a latent profile approach based on personality traits in Chinese young adolescent by Jingyue Hao, Zhenjiang Liao, Qiuping Huang, Xinxin Chen, Shuhong Lin, Yongyan Shi, Yifan Li, Yin Tang, Xuhao Wang, Hongxian Shen

“…High-risk gamers demonstrated elevated levels of neuroticism, accompanied by lower scores in other Big Five personality traits. …”
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Reducing the dietary starch:protein ratios in low-protein diets enhanced the growth performance of goslings from 1 to 28 days of age by Xucheng Zheng, Qian Lu, Chunhui Huang, Usman Nazir, Zhi Yang, Haiming Yang, Zhiyue Wang

“…Reducing the dietary S: P ratio elevated serum lipid concentration. In reduced S: P ratio diets, serum Leucine (Leu) decreased and Threonine (Thr) concentration increased. …”
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