Glucometabolic-Related Genes as Diagnostic Biomarkers and Therapeutic Targets for Alzheimer’s Disease and Type 2 Diabetes Mellitus: A Bioinformatics Analysis by Shuo Liu, He Chen, Xiao-Dong He, Xiao-Ou Yang

“…Similarly, in the T2DM murine model, elevated expression levels of G6pd, Pfkl, Eno3, and Pgd were observed. …”
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Exploring the therapeutic potential of 18β-Glycyrrhetinic acid in pulmonary arterial hypertension by integrating network pharmacology and experimental validation by Wenli Yang, Long Ma, Meidong Si, Fang Zhao, Ru Zhou

“…Background: Pulmonary arterial hypertension (PAH) is characterized by elevated pressure in the pulmonary arteries and can result in right heart failure and possible death.18β-Glycyrrhetinic acid (18β-GA), a beneficial substance found in licorice, shows great potential for medicinal use. …”
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The key role of the NUDT3 gene in lung adenocarcinoma progression and its association with the manganese ion metabolism family by Deyong Ge, Xinyu Xu, Liyi Fang, Huihui Tao

“…Single-cell transcriptomic analyses demonstrated elevated NUDT3 expression in lung adenocarcinoma epithelial cells, with expression levels increasing in cells associated with advanced tumor stages. …”
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GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease by Wang Y, Fang J, Yuan Q, Yu J, Hu J

“…Emerging evidence suggests a strong link between moderate to severe TBI and an elevated risk of PD, though the underlying mechanisms remain poorly understood.Materials and Methods: Common differentially expressed genes (DEGs) were identified in GEO datasets of patients with traumatic brain injury (TBI) and Parkinson’s disease (PD). …”
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Depressive symptoms and quality of life among women experiencing infertility: The moderating effect of perceived social support by Minjeong Jo, Hyewon Shin, Angela Kabbe, Shin-Jeong Kim

“…Background: Infertility constitutes a leading reproductive health problem with profound psychosocial outcomes, including elevated depressive symptoms that compromise quality of life (QoL). …”
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Effective treatment of severe acute pancreatitis and COVID-19 pneumonia with tocilizumab by Piotr Zielecki, Magdalena Kaniewska, Mariusz Furmanek, Tomasz Bulski, Grażyna Rydzewska

“…To date, it is not known if SARS-CoV-2 can cause pancreatic cell damage leading to acute pancreatitis, but in many cases serum lipase and amylase levels are elevated [8]. A study also showed that patients with history of acute pancreatitis may be more susceptible to COVID-19, but the mechanism of this phenomenon is not known yet [9]. …”
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Associations between mental illness, TB risk and migrant status by S.E. Hayward, K.L. Kristensen, A. Deal, J.H. Petersen, T. Lillebaek, S. Hargreaves, M. Norredam, J.S. Friedland

“…RESULTS: Both migrants and non-migrants with mental disorders showed elevated TB incidence (n = 1,189,273). After adjusting for age and sex, the hazard ratio (HR) for TB in those with any mental disorder was 3.62 (95% CI 2.99–4.39, n < 0.001) compared to those without mental disorders. …”
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Particle-bound PAHs and Chemical Composition, Sources and Health Risk of PM2.5 in a Highly Industrialized Area by Elizabeth Vega, Diego López-Veneroni, Omar Ramírez, Judith C. Chow, John G. Watson

“…., tires and industrial waste) of the recycling cement kilns and incinerators resulted in elevated toxic species such as, Cd, and Sb in the range of 0.02–0.3 µg m−3. …”
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Association of uric acid with the decline in estimated glomerular filtration rate in middle-aged and elderly populations: evidence based on the China Health and Retirement Longitud... by Ying Liang, Ming Lei, Liu Lin, Peijia Liu, Sini Cui, Kaiyuan Hu, Xinning Shao

“…After multivariable adjustment, the OR of the decline in eGFR was higher for quartile 2 (3.5–&lt;4.2 mg/dL: OR 1.44; 95% CI 1.07 to 1.64; p&lt;0.01), quartile 3 (4.2–&lt;5.0 mg/dL: OR 1.72; 95% CI 1.36 to 2.18; p&lt;0.001) and quartile 4 (≥5.0 mg/dL: OR 2.04; 95% CI 1.58 to 2.63; p&lt;0.001) when compared with quartile 1 (&lt;3.5 mg/dL), and the p value for the trend was &lt;0.001.Conclusions Over a 4-year follow-up period, we found that elevated UA was associated with a decline in eGFR in the middle-aged and elderly individuals with normal renal function.…”
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Achieving Medication‐Free Remission in Patients With Juvenile Dermatomyositis by Ilaria Maccora, Hermine I. Brunner, Amy Cassedy, Mekibib Altaye, Megan Quinlan‐Waters, Daniel J. Lovell, Alexei Grom, Sheila T. Angeles‐Han

“…MFR was more common in those who were younger at JDM diagnosis (median 5 vs 8 years, P = 0.008), had early resolution of disease activity (median 11 vs 18 months, P < 0.001), and presented with Gottron papules (χ2 = 5.25; P = 0.022) and elevated lactate dehydrogenase (χ2 = 4.82, P = 0.028). …”
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Evaluation of Intraperitoneal [18F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity by Els F. Halff, Sridhar Natesan, David R. Bonsall, Mattia Veronese, Anna Garcia-Hidalgo, Michelle Kokkinou, Sac-Pham Tang, Laura J. Riggall, Roger N. Gunn, Elaine E. Irvine, Dominic J. Withers, Lisa A. Wells, Oliver D. Howes

“…Following subchronic ketamine administration, elevated KiMod as compared to control condition was measured with a large effect size for both methods (intraperitoneal: Cohen’s d=1.3; intravenous: Cohen’s d=0.9), providing further evidence that ketamine has lasting effects on the dopamine system, which could contribute to its therapeutic actions and/or abuse liability.…”
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Genome-wide identification of CAMTA gene family in teak (Tectona grandis) and functional characterization of TgCAMTA1 and TgCAMTA3 in cold tolerance by Wenlong Zhou, Jian Du, Runjie Jiao, Xianbang Wang, Tiansong Fang, Guihua Huang

“…Moreover, under low-temperature conditions, TgCAMTA3-overexpressing Arabidopsis presented significantly elevated expression levels of genes related to the CBF signaling pathway, including AtCBF1/2/3. …”
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Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up: The Malmö Diet and Cancer Study by Jacob Hartz, Ronald M. Krauss, Mikael Göttsater, Olle Melander, Peter Nilsson, Michele Mietus-Snyder

“…Due to the collinearity of very small, small, and medium LDL particles and dyslipidemia (elevated TG and decreased HDL-c), the observed relationship between c-fPWV and high-risk LDL particles became insignificant after controlling for the concentration of HDL-c, large cholesterol-rich HDL particles, and TG. …”
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Dynamic responses characteristics of bedrock and overburden layer slope with anchored frame piles based on shaking table test by Lei Wang, Qianhui Pu, Guangpeng Chen, Jing Lian, Changwei Yang, Mingming Dai

“…Below the sliding surface of the front pile and on top of the bedrock of the back pile are the critical areas for prevention and control. Elevating the prestressing of the anchor cables will help enhance the synergy between the anchor cables and the piles. …”
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Features of the course of post-COVID-19 primary and recurrent herpetic keratitis by G.I. Drozhzhyna, K.V. Sereda, N.I. Khramenko

“…In patients with ulcerative necrotizing HK, the level of HSV IgG was 1.6 times higher than in patients with epithelial HK, and 1.5 times higher than in patients with non-necrotizing stromal HK. Elevated anti-VZV, anti-EBNA, and anti-CMV IgG levels were found in 93.2%, 76.4%, and 86.4%, respectively, of the examined patients. …”
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Alleviatory efficacy of achillea millefolium L. in etoxazole-mediated toxicity in allium cepa L by Zeynep Şule Topatan, Tuğçe Kalefetoğlu Macar, Oksal Macar, Emine Yalçin, Kültiğin Çavuşoğlu, Ali Acar, Fatih Kutluer

“…The levels of malondialdehyde and antioxidant enzyme (superoxide dismutase and catalase) activities were also elevated. Epidermis cell damage, flattened cell nucleus, thickened cortex cell wall, and thickened conduction tissue were the meristematic cell disorders triggered by etoxazole. …”
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In vitro and in silico Anti-diabetes mechanism of phytochemicals from Curculigo pilosa and its pharmacokinetic profiling via α-amylase inhibition by Damilola A. Omoboyowa, Temitope C. Aribigbola, Simbo T. Akinsulure, Damilola S. Bodun, Ezekiel A. Olugbogi, Ebenezer A. Oni

“…Diabetes mellitus is characterized by elevated blood glucose resulting from carbohydrate metabolism via glucose metabolizing enzymes such as α-amylase. …”
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The Effectiveness of β-glucan in the Treatment of Caprine Mastitis Induced by Candida albicans by Saddam H Mahmoud, Shaimaa N Yassein

“…Serum IL-6 and IFN-γ levels were significantly elevated in the positive control group, while the β-glucan-treated group showed a substantial reduction in these inflammatory markers, indicating its potential as a standalone antifungal therapy. …”
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Effects of Nitrogen Fertilization on Soil CH₄, CO₂, and N₂O Emissions and Their Global Warming Potential in Agricultural Peatlands by Yao Shi, Xiaowei Wei, Lianxi Sheng, Xuechen Yang

“…In the soil profile, N fertilization had a significant effect on CO₂ from 0 to 60 cm, resulting in an increase in CO₂ concentrations of 14–132%, whereas the top 30 cm of soil was the zone of significant N fertilization effects, with CH₄ concentrations decreasing by 49–95% and N₂O concentrations increasing by 22–26%. Elevated soil pH and NH₄⁺ were the key environmental factors influencing CH₄, CO₂ and N₂O emissions and their resulting increase in GWP. …”
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The effect of ethanol extract of Aloysia triphylla on anesthesia and improve the physiological parameters of rainbow trout (Oncorhynchus mykiss) after transfer by Ali Hajibeglou, Masoumeh Machanlou, Mohammad Mazandarani, Mohammad Sudagar

“…Results and discussion: The results showed that the elevated concentration of A. triphylla proportionally decreased the time required for sedation and anesthesia induction and upraised the recovery time. …”
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