Postoperative Pain and Opiate Requirement is Increased Following Second-Side Surgery Among Patients Undergoing Staged Total Knee Arthroplasty by Vivek P. Chadayammuri, MD, Shuvalaxmi D. Haselton, MS, Elizabeth Diaz, PA-C, Roger H. Emerson, MD

“…Female patients were increasingly susceptible to elevated pain levels following second-side TKA (β = 0.372; P = .057). …”
Get full text

Observation-driven model for calculating water-harvesting potential from advective fog in (semi-)arid coastal regions by F. Lobos-Roco, F. Lobos-Roco, J. Vilà-Guerau de Arellano, C. del Río, C. del Río

“…AMARU's outputs are validated against in situ observations collected over Chile's coastal (semi-)arid regions at various elevations and during various years (2018–2023). The model's representations of the seasonal cycle of fog harvesting follow observations, with errors of <span class="inline-formula">∼</span> 10 <span class="inline-formula"><i>%</i></span>. …”
Get full text

Improving natural red pigment production by Streptomyces phaeolivaceus strain GH27 for functionalization of textiles with in silico ADME prediction by Gehad H. El Sayed, Mohamed Fadel, Rasha Fouad, Hend M. Ahmed, Ahmed A. Hamed

“…It exhibited intermediate synthetic accessibility, exceptional permeability and absorption, elevated gastrointestinal absorption, and blood–brain barrier penetration; nonetheless, it did not adhere to the medicinal chemistry rule of three. …”
Get full text

Entre la creatividad y el recuerdo: el espacio de juego en el arte de instalación de Carsten Höller y Gelitin by Javier Gómez Chozas, Vanesa Cejudo Mejías, Arturo Franco Díaz

“…Tomando como ejemplo las obras Test Site (2006), del artista alemán Carsten Höller, y Human Elevator (1999-2016), del colectivo austríaco Gelitin, se comparan las obras para llegar a diversas conclusiones acerca de la inserción del juego infantil en la programación de exposiciones en las instituciones artísticas. …”
Get full text

Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats by Awyed Batah Almutairi, Abdulaziz Arif A. Alshammari, Arshad Husain Rahmani, Ali Yousif Babiker, Long Chiau Ming, Maha A. Aldubayan, Ahmad H. Alhowail, Vasudevan Mani

“…Behavioural assessments included the elevated plus maze (EPM) and novel object recognition (NOR) tests used to evaluate memory capabilities and recognition memory respectively, and the Y-maze assessed the exploration of a new environment and navigational skills. …”
Get full text

Exploring pre-exposure prophylaxis (PrEP) modality preferences among black cisgender women attending family planning clinics in Chicago via a cross-sectional mixed-methods study by Sadia Haider, Amy K Johnson, Emily Ott, Eleanor E Friedman, Agustina Pandiani, Amy Moore, Isa Alvarez, Catherine Desmarais

“…Background Despite pre-exposure prophylaxis (PrEP) demonstrated effectiveness, black cisgender women continue to be at an elevated risk for HIV acquisition and uptake of daily oral PrEP is low in this population in the USA. …”
Get full text

Clinical Value of Asymmetrical Dimethylarginine Detection in Patients with Connective Tissue Disease-Associated Pulmonary Arterial Hypertension by Juan Liu, Qiang Fu, Lili Jiang, Youlian Wang

“…Multivariate analysis indicated that elevated serum ADMA levels increased the risk for the appearance of PAH in CTD patients (OR = 57.460, P<0.001). …”
Get full text

Neuropsychological morbidity in the First Seizure Clinic: Prominent mood symptoms and memory issues in epilepsy by Remy Pugh, David N. Vaughan, Graeme D. Jackson, Jennie Ponsford, Chris Tailby

“…Clinically significant depressive symptoms were similarly prevalent in all patient groups, with one in three at risk for Major Depressive Disorder. Elevated anxiety symptoms were common across patient groups; however, not significantly different to controls. …”
Get full text

Timed Bromocriptine-QR Therapy Reduces Progression of Cardiovascular Disease and Dysglycemia in Subjects with Well-Controlled Type 2 Diabetes Mellitus by Bindu Chamarthi, J. Michael Gaziano, Lawrence Blonde, Aaron Vinik, Richard E. Scranton, Michael Ezrokhi, Dean Rutty, Anthony H. Cincotta

“…However, other risk factors such as elevated vascular sympathetic tone and/or endothelial dysfunction may be stronger potentiators of CVD. …”
Get full text

Therapeutic effects of Pueraria lobata (Willd.) Ohwi root and Hovenia dulcis Thunb. extracts on alcoholic liver disease: Network pharmacology and experimental validation by Zhendong Chen, Yu Yue, Hongyan An, Haisu Yan, Hyeok-Joo Park, Pei Lin

“…Results: Treatment with the extract contributed to a significant reduction in the release of nitric oxide and reactive oxygen species in the ethanol-treated HepG2 cells; promoted the elevated expression of superoxide dismutase, catalase, and glutathione, indicating enhanced antioxidant defenses; and showed strong free radical-scavenging activity against 1,1-diphenyl-2-picrylhydrazyl radicals. …”
Get full text

Colors and Learner’s Gender Evoke Different Emotional and Cognitive Effects in Multimedia Learning by Tze Wei Liew, Su-Mae Tan, Chin Lay Gan, Wei Ming Pang

“…The emotional design principle avers that highly saturated warm colors in multimedia learning presentations can elevate affective-motivational, cognitive, and learning outcomes. …”
Get full text

Cell-free DNA release following psychosocial and physical stress in women and men by A. S. Limberg, F. Berg, E. Köper, C. Lindgraf, C. Gevers, R. Kumsta, E. M. Hummel, D. A. Moser

“…The analysis indicated significantly elevated levels of cf-nDNA in both plasma and saliva in all participants, irrespective of gender, following psychosocial and physical stress. …”
Get full text

A single-center, single-arm, prospective, open-label, and comparative trial to evaluate the safety and tolerability profile of a 90-day oral L-arginine hydrochloride intervention f... by Hiroyuki Naito, Masahiro Nakamori, Megumi Toko, Yuki Hayashi, Taku Tazuma, Tomoaki Watanabe, Keito Ishihara, Keisuke Tachiyama, Yu Yamazaki, Hirofumi Maruyama

“…Six participants (30%) experienced treatment-emergent adverse events (TEAEs), including elevated creatine kinase levels, liver function test abnormalities, glucose tolerance issues, hyperammonemia, anorexia, dysgeusia, and vasculitis. …”
Get full text

Heterogeneous Acupuncture Effects of Taixi (KI3) on Functional Connectivity in Healthy Youth and Elder: A Functional MRI Study Using Regional Homogeneity and Large-Scale Functional... by Linlu He, Guangxiang Chen, Ruwen Zheng, Yan Hu, Xiu Chen, Jianghai Ruan

“…Furthermore, the internetwork FC between subcortical and dorsal attention and between subcortical and cerebellar showed the most obvious elevations after needling in the HY group. In the elder group, both FCs of internetwork and intranetwork primarily involving sensory/somatomotor, cingulo-opercular, and dorsal attention were declined after acupuncture. …”
Get full text

Examining the reach of a diabetes screening program in an urban emergency department by Ruth A. Pobee, Kirstie K. Danielson, Angela Kong, Yuval Eisenberg, Brian T. Layden, Janet Lin

“…Almost half (47 %, n = 2808) had elevated A1c levels indicative of prediabetes (n = 2070; A1c: 5.7–6.4 %) or diabetes (n = 738; A1c: ≥6.5 %). …”
Get full text

Association of Albumin‐To‐Creatinine Ratio With Diabetic Retinopathy Among US Adults (NHANES 2009–2016) by Han Dai, Ling Liu, Weiwei Xu

“…Receiver operating characteristic (ROC) curve analysis evaluated the predictive accuracy of individual biomarkers and combined models. Results Elevated SACR levels were inversely related to DR risk, while UACR showed a positive correlation. …”
Get full text

Apoptosis antagonizing transcription factor expression and its validation as a potential diagnostic and prognostic biomarker in oral squamous cell carcinoma by Ainiwaerjiang Abudourousuli, Zumulaiti Aierken, Hasiyati Mamuti, Tuxunayi Yimamu, Chengli Da

“…Validation via qRT-PCR confirmed the overexpression of AATF in OSCC tissues.ConclusionElevated expression of AATF in OSCC correlates with adverse clinicopathological features and negatively impacts immune cell infiltration. …”
Get full text

Clinical and Hematological Manifestation of Dengue Patients in 2022 Outbreak: A Tertiary Care Hospital‐Based Cross‐Sectional Study by Md. Jubayer Hossain, Manisha Das, Muhibullah Shahjahan, Md. Wahidul Islam, Syeda Tasneem Towhid

“…Thrombocytopenia was present in 61% of patients, with 79% showing elevated hematocrit (HCT) levels. Pedal edema, pleural effusion, and ascites were observed in DF and DFWS cases, while SD cases exhibited distinct HCT level variations. …”
Get full text

Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis by Anqi Wang, Sitong Yan, Weijia Jiang, Xiang Chen, Yuhan Huang, Xiangyu Zu, Xiao Du, Lulu Fan, Jiatao Liu, Guoping Sun

“…Results Analysis of TCGA datasets and tissue microarrays demonstrated that elevated CLIP4 expression was associated with poor prognosis in HCC. …”
Get full text

Gyrfalcon Prey Abundance and Their Habitat Associations in a Changing Arctic by Michaela Gustafson, Jennifer D. McCabe, Brian W. Rolek, Travis L. Booms, Michael T. Henderson, Leah Dunn, David L. Anderson, Jennyffer Cruz

“…Arctic ground squirrels were more abundant at higher elevations with greater cover of sparse vegetation and low shrubs. …”
Get full text