Determinants of mortality and prolonged hospital stay among dengue patients attending tertiary care hospital: a cross-sectional retrospective analysis by Yusra Habib Khan, Tauqeer Hussain Mallhi, Amer Hayat Khan, Azmi Sarriff, Azreen Syazril Adnan

“…Multivariate analysis showed that dengue haemorrhagic fever (OR 2.3), elevated alkaline phosphatase (ALP) (OR 2.3), prolonged prothrombin time (PT) (OR 1.7), activated partial thromboplastin time (aPTT) (OR 1.9) and multiple-organ dysfunctions (OR 2.1) were independently associated with prolonged hospitalisation. …”
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Pulmonary function in swimmers exposed to disinfection by-products: a narrative review by Michał Boraczyński, Tomasz Balcerek, Nikola Rożkiewicz, Monika Pabiszczak, Michał Harasymczuk, Aneta Sławska, Przemysław Lutomski

“…The association between long-term exposure to a chlorinated swimming pool and elevated serum sIgE levels suggests a link between allergens, chlorine exposure and the development of various pulmonary dysfunctions. …”
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Prognostic Significance of Admission CRP Levels as a Predictor of Mortality in Burn Patients by Maria Syed, Qaiser Jehangir, Ijaz Hussain Shah, Sana Shaukat Siddiqui, Sara Ishaq, Sarah Zaka

“…Non-survivors had significantly higher total body surface area burned (41.3% vs 22.7%) and elevated C-reactive protein (CRP) levels at admission (23.5 mg/L vs 10.6 mg/L) compared to survivors. …”
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Oral Immunisation With Non‐GMO Surface Displayed SARS‐CoV‐2 Spike Epitopes on Bacteria‐Like Particles Provokes Robust Humoral and Cellular Immune Responses, and Modulated the Gut M... by Robie Vasquez, Ji Hoon Song, Remilyn M. Mendoza, In‐Chan Hwang, Bernadette B. Bagon, Lars Engstrand, Valerie Diane Valeriano, Dae‐Kyung Kang

“…Moreover, the immunisation exhibited a Th1‐like immune response, characterised by an elevated IgG2a‐to‐IgG1 ratio and high antiviral IFN‐γ production. …”
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Skin Microbiota: Mediator of Interactions Between Metabolic Disorders and Cutaneous Health and Disease by Magdalini Kreouzi, Nikolaos Theodorakis, Maria Nikolaou, Georgios Feretzakis, Athanasios Anastasiou, Konstantinos Kalodanis, Aikaterini Sakagianni

“…Advances in metabolomics and microbiome sequencing have unveiled critical biomarkers, such as short-chain fatty acids and microbial signatures, predictive of therapeutic outcomes. For example, elevated butyrate levels in psoriasis have been associated with reduced Th17-mediated inflammation, while the presence of specific Lactobacillus strains has shown potential to modulate immune tolerance in atopic dermatitis. …”
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The effects of Bifidobacterium animalis QC08 on reducing uric acid level and providing renal protection in mice with hyperuricemia by Huijia Mao, Yang Fan, Fang Tan, Xingyao Long

“…Pathological changes in renal tissue were examined through hematoxylin–eosin (HE) staining.ResultsIn vivo experimental results indicated that compared with the normal group, the serum UA, Cr, and BUN levels, as well as the levels of inflammatory factors (TNF-α and IL-1β), and the activities of hepatic xanthine oxidase (XOD) and adenosine deaminase (ADA) were significantly elevated in the control group (p < 0.05). The expression levels of uric acid transport-related genes (UAT, ABCG2, and OAT1) in kidney tissue were significantly downregulated (p < 0.05), and evident kidney damage was found. …”
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Advancements in end treatment techniques and applications of acid mine drainage in coal mines: A research review by Qiaohui CHE, Song DU, Degao ZHANG, Yinglin FAN, Xiao ZHANG, Fengli WANG

“…Acid mine drainage(AMD) from coal mines contains elevated concentrations of heavy metals and sulfates, rendering it highly corrosive and posing a persistent threat to both the ecological environment and human health. …”
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Establishment of a metabolite diagnostic model for the risk of diabetic nephropathy in type 2 diabetic population: Based on a cross-sectional study in China by Jing-Yang Su, Yong-Jie Chen, Wei Zhang, Rui Zhang, Tong-Feng Liu, Wei-Ming Luo, Xi-Lin Yang, Zhong-Ze Fang

“…Compared with the non-DN group, the DN group exhibited elevated systolic blood pressure (P ​= ​0.001), high-density lipoprotein cholesterol (P ​= ​0.01), and low-density lipoprotein cholesterol (P ​= ​0.042). …”
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Shenmai injection revives cardiac function in rats with hypertensive heart failure: involvement of microbial-host co-metabolism by Lin Li, Senjie Zhong, Jiahao Ye, Siyuan Hu, Xiajun Xiong, Guangyu Chen, Zhixi Hu

“…Abstract Heart failure (HF) is a complex syndrome marked by considerable expenditures and elevated mortality and morbidity rates globally. Shenmai injection (SMI), a form of Traditional Chinese Medicine-based therapy, has demonstrated effectiveness in treating HF. …”
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Variability and clinical value of troponin T levels in diabetic kidney disease patients treated with dialysis by Yu Rui, Cheng Cui-cui, Zhang Shan, Yang Xiao-xia, Sun Xin-yu, Gao Qing-zhen

“…With the increase in baseline TnT， the rate of myocardial infarction， psychogenic mortality， diabetic foot ulcer， and all-cause mortality increased in DKD dialysis group.ConclusionBaseline TnT is significantly higher in the DKD dialysis group than that of the NDKD dialysis group， and a higher threshold is required for the diagnosis of acute myocardial infarction. Elevated baseline TnT level is influenced by factors such as diabetic vascular complications， which can be used as a prognostic indicator for adverse events.…”
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Jiangzhi Granule Ameliorates JNK-Mediated Mitochondrial Dysfunction to Reduce Lipotoxic Liver Injury in NASH by Jiang Y, Xu J, Ding J, Liu T, Liu Y, Huang P, Wang Q, Zheng P, Song H, Yang L

“…In NASH mice, JZG reduced hepatosteatosis, and inflammatory infiltration, and improved mitochondrial morphology and quantity in liver tissues. Additionally, elevated phosphorylation ratio of non-receptor tyrosine kinase c-Src (Src) and reduced phosphorylation ratio of JNK and SH2-containing protein tyrosine phosphatase (SHP-1) were found in both hepatocytes and mice liver tissues treated with JZG versus those with the vehicle.Conclusion: Taken together, JZG could improve mitochondrial dysfunction and reduce lipotoxic liver injury in NASH in vivo and in vitro models. …”
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Combined effect of exercise and curcumin on inflammation-associated microRNAs and cytokines in old male rats: A promising approach against inflammaging by Zahra Shargh, Keyvan Asghari, Morteza Asghariehahari, Leila Chodari

“…Results: Our findings revealed that the Old control group, in contrast to the Young control group, showed a significant reduction in IL-10 serum levels, while MDA, TNF-α, IL-1β, and IL-6 serum levels were significantly elevated. Additionally, the expression of inflammatory microRNAs (miRNAs), miR-21 and miR-146a, was significantly enhanced in the Old control rats compared with the Young control group. …”
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Relationships between diabetes distress and biomarkers in people with type 1 diabetes mellitus by V.I. Pankiv, T.Yu. Yuzvenko, G.P. Mykhalchyshyn

“…Understanding the causes of elevated glycemic levels in T1DM patients may help tailor diabetes management interventions to improve health outcomes.…”
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Overlooking the Obvious during the COVID-19 Pandemic: Dyspnoea with Asymmetric Breath Sounds in a Toddler by Heli Salmi, Heini Harve-Rytsälä, Paula Rautiainen, Sari Pyörälä, Johanna Hästbacka

“…An ambulance was called, and he was taken to a tertiary hospital’s paediatric emergency department, where his condition and oxygen saturation fluctuated. He had mildly elevated temperature and petechiae on his trunk, showed asymmetrical radiographic and auscultatory pulmonary findings, and did not tolerate any exertion. …”
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Application Value of STOP-Bang Questionnaire in Predicting Abnormal Metabolites by Pang Q, Han L, Li J, Xu L, Wang Y

“…A higher SBQ score indicated elevated uric acid (UA), waist circumference (WC), fasting blood glucose (FBG), hemoglobin A1c (HbA1c) and triacylglycerol (TG), but notably lower high density lipoprotein-cholesterol (HDL-C). …”
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A Review of Potentially Toxic Elements in Sediment, Water, and Aquatic Species from the River Ecosystems by Md Muzammel Hossain, Iffat Jahan, Mudasir A. Dar, Maruti J. Dhanavade, Al Fattah Bin Mamtaz, Stephen J. Maxwell, Song Han, Daochen Zhu

“…A comprehensive study suggests elevated PLI values in river sediments, indicating significant pollution levels, particularly in the Buriganga River sediment, marked by high Igeo values. …”
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Association between triglyceride-glucose index and clinical outcomes among patients with chronic kidney disease: a meta-analysis by Jinli Tuo, Zhong Li, Linshen Xie

“…Pooled results indicated that elevated TyG index was significantly related to increased risk for all-cause mortality (HR = 1.22, 95% CI: 1.13–1.31, P<0.001). …”
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Evaluation of de novo donor specific antibodies after kidney transplantation in the era of donor-derived cell-free DNA by Yuan Tian, Lukas Frischknecht, Anna Mallone, Fabian Rössler, Thomas Schachtner, Jakob Nilsson

“…BackgroundDonor-derived cell-free DNA (dd-cfDNA) is a promising non-invasive biomarker for detecting graft injury in solid organ transplant recipients. Elevated dd-cfDNA levels are strongly associated with rejection and graft injury, especially antibody-mediated rejection (ABMR). …”
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Mind at rest, mind at risk: A prospective population-based study of sleep and subsequent mental disorders by Mari Hysing, Allison G. Harvey, Ann Kristin Skrindo Knudsen, Jens C. Skogen, Anne Reneflot, Børge Sivertsen

“…Sleep duration showed a reversed J-shaped association with mental disorders, with both short and, to a lesser extent, long sleep durations linked to elevated risks, even after adjusting for baseline mental health symptoms and somatic conditions. …”
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Achillea millefolium capsule improved liver enzymes and lipid profile compared to placebo in patients with type 2 diabetes: a double-blind randomized clinical trial by Shole Daneshvar-Ghahfarokhi, Hassan Ahmadinia, Tabandeh Sadeghi, Elham Basirat, Vahid Mohammadi-Shahrokhi

“…Considering the abnormal lipid levels and elevated liver enzymes in diabetic patients, this study was conducted to investigate the effect of AM on the lipid profile and serum level of liver enzymes in type 2 diabetic (T2D) patients. …”
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