Association between systemic immune-inflammation index and the risk of all-cause, cancer and non-cancer mortality in the general population: results from national health and nutrit... by Siyu Wu, Zhao Liu, Xing Li, Shan Gao, Peng Xia

“…Conclusion Our findings imply that SII can serve as a potential prognosis indicator among general population. Elevated SII is associated with higher all-cause and non-cancer mortality. …”
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China’s CBM exploration and production and associated technological advancements: A review and reflections by Jianping YE

“…The breakthroughs in the ideological understanding of exploration and production, as well as the innovative applications of near-bit geosteering drilling technology and multistage volume fracturing technology for horizontal wells, elevate China’s deep CBM production to a higher level. …”
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Chronic pain is a risk factor for all-cause and cancer-specific mortality in cancer survivors: a population-based cohort study by Yeying Zhang, Yuna Guo

“…Compared with non-chronic pain survivors, chronic pain correlated with elevated all-cause mortality (Hazard Ratio (HR), 1.40; 95% CI, 1.14–1.72, p = 0.001) and cancer death (HR, 1.75; 95% CI, 1.16–2.64, p = 0.008), primarily in patients with pain lasting 3 months or more. …”
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Understanding the Effects of Selected Backpack Loads Carried for Certain Durations on Peak Forces of Walking Gait in School-Going Boys by Rabiya Husain, Dessalegn Wase Mola, Dhananjoy Shaw

“…The right foot exhibited elevated forces at the first peak, while the left foot showed dominance at the second peak. …”
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Diagnostic potential of CDK1 and STAT1 in acute kidney injury associated with gastrointestinal cancers: a bioinformatics-based study by Qiuwan Wei, Yiqing Shen, Yiren Tian, Yunzhi Ling

“…Immunohistochemical analysis revealed elevated H scores for CDK1, STAT1, COL1A2, and COL1A1 in tumor tissues. …”
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The relationship between stress, social support, and quality of life among spouses of patients at the end-of-life stage in Thailand: A correlational study by Rathapon Thawonphat, Tiraporn Junda, Bualuang Sumdaengrit

“…Spousal caregivers often face emotionally distressing circumstances while caring for their loved ones, which can lead to elevated stress levels. However, research indicates that adequate social support can improve caregivers’ quality of life, reducing some of the burdens associated with end-of-life care. …”
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Extracorporeal membrane therapy in a case of ruptured abscess on the mitroaortic intervalvular fibrosa associated to multisystem inflammatory syndrome: a case report by Lina P. Montaña-Jimenez, Ana M. Aristizabal, Carlos A. Guzmán-Serrano, Cesar Cely Reyes, Juan Fernando Vélez Moreno, Gastón Castillo

“…On the other hand, the COVID-19 pandemic notably impacted pediatric patients with congenital heart diseases, who frequently presented cardiac complications including arrhythmias, elevated troponins, myocarditis, and heart failure. …”
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Systemic Immune-Inflammation Index: A Promising, Non-Invasive Biomarker for Crohn’s Disease Activity and Severity Assessment by Deng Y, Fu T, Gao D, Zhou J, Nie X, Wang F, Yu Q

“…SII was significantly elevated in active CD (p< 0.001), correlating with disease severity (p< 0.001). …”
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Repression of PFKFB3 sensitizes ovarian cancer to PARP inhibitors by impairing homologous recombination repair by Yinan Xiao, Yu Wu, Qilong Wang, Mo Li, Chaolin Deng, Xiaoyang Gu

“…Results PFKFB3 activity was significantly elevated in OC tissues and associated with PARPi resistance. …”
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Exploring the prevalence of gout among underrepresented low socioeconomic status type 2 diabetes populations by Jessica Smith, Abey Martin, Jane Mundadan, Michael Roberts, Youssef Roman, Arturo Bravo-Nuevo, Farzaneh Daghigh

“…Gout is a chronic inflammatory disease affecting joints in the lower limbs, marked by elevated serum urate levels and the accumulation of uric acid crystals in synovial fluid, causing painful flare-ups that significantly impact quality of life. …”
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miR-21 and cathepsin B in familial Mediterranean fever: novel findings regarding their impact on disease severity by Emrah Yucesan, Mehmet Yildiz, Ramila Hajiyeva

“…Serum miR-21-5p expression levels were assessed by qRT-PCR, while serum pyrin, IL-1β and cathepsin B levels were determined by ELISA.Results Serum miR-21-5p was significantly downregulated in FMF patients compared with the control group (p&lt;0.001), while serum pyrin, IL-1β and cathepsin B levels were markedly elevated (p&lt;0.001 for each). Only miR-21-5p was negatively correlated with IL-1β (r=−0.855; p&lt;0.001). …”
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The effects of interaction between smoking and abdominal obesity on pre-diabetes mellitus by Huali Xiong, Peng Zhao, Fengxun Ma, Dayi Tang, Daiqiang Liu

“…Following adjustments for confounding variables, current smoking (OR = 1.26, 95%CI:1.04–1.52) and abdominal obesity (OR = 1.4, 95%CI:1.18–1.66) were significantly linked to an elevated risk of PDM. The multiplicative interaction analyses demonstrated that current smoking exhibited a positive association with PDM (OR = 1.32, 95%CI:1.01–1.71), while a similar association was not observed in the case of abdominal obesity with PDM (OR = 1.15, 95%CI:0.94–1.4). …”
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The Relationship between Red Blood Cell Distribution Width and Incident Diabetes in Chinese Adults: A Cohort Study by Jialu Wang, Yanan Zhang, Yanping Wan, Zhuping Fan, Renying Xu

“…Sensitivity analysis generated similar results with prospective analyses after excluding aged participants, participants who are overweight and with obesity, participants with elevated blood pressure, participants with decreased eGFR, and those with anemia at baseline. …”
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Prognostic implications of system inflammation response index in atrial fibrillation patients with type 2 diabetes mellitus by Yang Chen, Bin Zhou, Chaoquan Peng, Yong Liu, Weiyan Lai

“…COX regression analysis revealed elevated SIRI levels as an independent risk factor for both in-hospital and 1-year mortality. 192 patients died during hospitalization, and 265 died during the follow-up of 1 year. …”
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Pain management in trauma: the need for trauma-informed opioid prescribing guidelines by Ben L Zarzaur, Suresh Agarwal, Colleen Trevino, Amelia Baltes, David M Horton, Julia Malicki, Randall T Brown

“…Background/objectives Surgical populations and particularly injury survivors often present with complex trauma that elevates their risk for prolonged opioid use and misuse. …”
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Recent advances in the application of Mendelian randomization to chronic kidney disease by Chaofan Wen, Lanlan Chen, Dan Jia, Ziqi Liu, Yidan Lin, Guan Liu, Shuo Zhang, Baoshan Gao

“…Notably, evidence indicates that elevated testosterone levels may impair renal function, while higher sex hormone-binding globulin (SHBG) levels appear to be protective, predominantly in men. …”
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Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia by Vijaya Prakash Krishnan Muthaiah, Kathiravan Kaliyappan, Ramkumar Thiayagarajan, Supriya Mahajan, Krishnamoorthy Gunasekaran

“…We found that ATP levels were elevated post‐BOP from both glycolysis and oxidative phosphorylation (OXPHOS), an increase of ATP by glycolysis more significant than OXPHOS source, indicating the proinflammation post‐BOP. …”
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Inhibition of TFF3 synergizes with c-MET inhibitors to decrease the CSC-like phenotype and metastatic burden in ER+HER2+ mammary carcinoma by Chuyu He, Xuejuan Wang, Yi-Shiou Chiou, Basappa Basappa, Tao Zhu, Vijay Pandey, Peter E. Lobie

“…Herein, the function and mechanism of TFF3 in ER+HER2+ MC were delineated; and novel combinatorial therapeutic strategies were identified. Elevated expression of TFF3 promoted the oncogenicity of ER+HER2+ MC cells, including enhanced cell proliferation, survival, anchorage-independent growth, 3D growth, cancer stem cell-like (CSC-like) phenotype, migration, invasion, and xenograft growth. …”
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Severe reversible cardiomyopathy associated with adrenal crisis caused by isolated adrenocorticotropin deficiency: a case report by Li Wang, Fangfang Bu, Lanjie He, Guihua Yao, Guihua Yao

“…The patients was initially diagnosed with “septic shock” because of elevated inflammatory indicators and treated with mechanical circulatory support, antibiotics, fluid resuscitation, and intravenous administration of 50 mg hydrocortisone every 6 h for 2 days (400 mg in total). …”
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Development and validation of a novel bleeding risk prediction tool for aspirin users with a low body mass index by Lu Yifang, Lei Wanlin, Wang Maofeng

“…However, in specific individuals, particularly those with low body mass index (BMI), aspirin can elevate the risk of bleeding. Achieving a delicate equilibrium between the desirable antiplatelet effects and potential bleeding complications is a notable consideration. …”
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