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6981
Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review
Published 2020-01-01“…We found 24 parameters that were increased only in active TB (TGF-α, CSF3, CSF2, CCL1 [I-309], IL-7, TGF-β1, CCL3 [MIP-1α], sIL-2R, TNF-β, CCL7 [MCP-3], IFN-α, fractalkine, I-TAG, CCL8 [MCP-2], CCL21 [6Ckine], PDGF, IL-22, VEGF-A, LXA4, PGE2, PGF2α, sCD163, sCD14, and 15-Epi-LXA4), five were elevated in LTBI (IL-5, IL-17F, IL-1, CCL20 [MIP-3α], and ICAM-1), and two substances were increased among uninfected individuals (IL-23 and basic FGF). …”
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6982
Effect of Nebivolol and Olmesartan on 24-Hour Brachial and Aortic Blood Pressure in the Acute Stage of Ischemic Stroke
Published 2019-01-01“…Background. Elevated blood pressure (BP) in the acute phase of ischemic stroke is associated with heightened risk of early disability and death. …”
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6983
Decrease of NAD+ Inhibits the Apoptosis of OLP T Cells via Inducing Mitochondrial Fission
Published 2025-01-01“…OLP T cells and OLP plasma-exposed Jurkat T cells were treated with either β-nicotinamide mononucleotide (an NAD+ synthesis precursor) or FK866 (an NAD+ synthesis inhibitor) to assess the effect of NAD+ regulation on mitochondrial remodeling and T cell apoptosis.Results: OLP T cells exhibited fragmented mitochondria with elevated dynamin-related protein 1 (Drp1) and reduced mitofusin 2 (Mfn2) expression, accompanied by decreased apoptosis. …”
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6984
Early Biomarkers for Detecting Subclinical Exposure to Fumonisin B1, Deoxynivalenol, and Zearalenone in Broiler Chickens
Published 2024-12-01“…On d14, birds in T6 showed significant upregulation of liver miRNAs, gga-let-7a-5p (14.17-fold), gga-miR-9-5p (7.05-fold), gga-miR-217-5p (16.87-fold), gga-miR-133a-3p (7.41-fold), and gga-miR-215-5p (6.93-fold) (<i>p</i> < 0.05) and elevated serum fluorescein isothiocyanate-dextran (FITC-d) concentrations, aspartate aminotransferase (AST), and creatine kinase (CK) levels compared to the control (<i>p</i> < 0.05). …”
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6985
Peculiarities of in-Stent Thrombosis and Restenosis in Coronary Arteries Post-COVID-19: A Systematic Review of Clinical Cases and Case Series
Published 2025-01-01“…In the patients with COVID-19 in intensive care units, the proportion of those with elevated troponin levels reached 25%.Objective: Evaluation of the association between COVID-19 and the development of in-stent thrombosis and restenosis of the coronary arteries based on the analysis of clinical cases and case series.Materials and Methods: We searched the PubMed and Scopus databases for relevant case reports and case series of stent restenosis and in-stent thrombosis associated with coronavirus infection (CVI) published between 2020 and the present. …”
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6986
New inflammatory markers associated with disease activity in rheumatoid arthritis: pan-immune-inflammation value, systemic immune-inflammation index, and systemic inflammation resp...
Published 2024-12-01“…Conclusions The findings revealed that PIV, SII, and SIRI were elevated in individuals with RA and may serve as complementary diagnostic markers. …”
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6987
Characterization of the Liquid Fuel Produced from Catalytic Depolymerization of Polymeric Waste Using Batch Reactor
Published 2024-12-01“…The technique involves heating the polymeric waste at an elevated temperature in an inert environment to produce condensable, non-condensable, hydrocarbon and biochar. …”
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6988
Aberrant SNHG expression predicts poor prognosis in esophageal cancer using meta-analysis and bioinformatics analysis
Published 2025-02-01“…Conversely, in populations with high expression of other SNHGs, SNHG expression indicated poor prognosis (OR: 2.340, 95%CI = 1.744–2.936). Elevated SNHG expression also implied advanced TNM stage (OR 1.578, 95%CI = 1.273–1.956) and lymph node metastasis (OR: 1.533, 95%CI = 1.205–1.950). …”
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6989
Evaluation of TNF-α, IL-10 and IL-6 Cytokine Production and Their Correlation with Genotype Variants amongst Tuberculosis Patients and Their Household Contacts.
Published 2015-01-01“…IL-6 levels also were elevated among APTB compared to HHC and HC, and a significant difference was observed between APTB and HHC at P<0.0001; APTB & HC at P< 0.04; HHC & HC at P< 0.01. …”
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6990
Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2.
Published 2023-10-01“…CD4+ helper T cells became activated upon ex vivo recall stimulation with SARS-CoV-2 nucleocapsid peptide library and exhibited elevated mRNA expression of the regulatory T cell cytokines interleukin-10 and transforming growth factor-β, which may have limited inflammatory pathology. …”
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6991
Increasing Thai Catfish's Immunity (Pangasius hypophthalmus Fowler) Using Ascorbic Acid
Published 2007-08-01“…The result of this experiment shown that feed with ascorbic acid of 2.000 mg/kg was elevated the cellular responses such as: leucocyte total (34.850 cels/mm3), differential of leucocyte (lymphocyte: 72,2%, monocyte: 8,0%, neutrophyl: 7,8%), phagocytic index (13%) and humoral response (titre antibody: 0.829 serum aglutination unit), which at the same time proves high level of survival rate against the artificial injection using A. hydrophila. …”
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6992
Exploring the association between pro-inflammatory diets and chronic liver diseases: evidence from the UK Biobank
Published 2025-01-01“…A higher DII, indicating a more inflammatory diet, was associated with a 16% increased risk of CLD [hazard ratio (HR) = 1.162, P = 0.001], with each unit increase in DII elevating the risk by 3.3% (HR: 1.033, P < 0.001). …”
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6993
Disorders of esophageal clearance in gastroesophageal reflux disease and option of their treatment
Published 2012-04-01“…The body mass index in group was elevated (mean —25,0 [24,2; 28,6] kg/m2). Patients underwent esophagogastroduodenoscopy (EGDS), 24-hour pH-metry, X-ray investigation with barium meal, investigation of esophageal motor function. …”
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6994
Achieving prediabetes reversal in China: a nationwide longitudinal study on the role of blood glucose and lipid management in middle-aged and elderly adults
Published 2025-01-01“…The stepwise logistic regression model identified older age, female sex, abdominal obesity (OR 0.70, 95% CI 0.57–0.86), elevated LDL-C (OR 0.69, 95% CI 0.48–0.97), higher FPG (OR 0.68, 95% CI 0.52–0.90), and higher HbA1c (OR 0.23, 95% CI 0.18–0.30) as factors associated with regression to NGR. …”
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6995
HBV DNA integration and somatic mutations in HCC patients with HBV-HCV dual infection reveals profiles intermediate between HBV- and HCV-related HCC
Published 2025-01-01“…Conclusions Our findings shed light on the interplay between preexisting CHB and subsequent CHC in elevating the risk of HBCV-HCC. These insights are crucial for understanding viral etiology-specific carcinogenesis and guiding surveillance policies for HBCV-HCC post-antiviral therapy.…”
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6996
MMP9-Associated Tumor Stem Cells, CCL1-Silenced Dendritic Cells, and Cytokine-Induced Killer Cells Have a Remarkable Therapeutic Efficacy for Acute Myeloid Leukemia by Activating T...
Published 2023-01-01“…In addition, we proved that MMP9- and CCL1-silenced DC-CIK cells significantly elevated the CD3+CD4+ and CD3+CD8+ cells and lowered the CD4+PD-1+ and CD8+PD-1+ T cells. …”
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6997
A novel approach for managing the incisions of tibial plateau fractures with soft tissue swelling
Published 2025-01-01“…The modified Rasmussen functional and radiological scores were elevated in both groups (P < 0.05). There was no statistically significant difference between the two groups for the modified Rasmussen functional or radiological score at any of the time points (P > 0.05). …”
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6998
Generation and characterization of chicken monocyte-derived dendritic cells
Published 2025-02-01“…Subsequent stimulation with lipopolysaccharide (LPS) or 24 h triggered phenotypic maturation of MoDCs, characterized by the increased surface expression of MHCII and co-stimulatory molecules CD80 and CD40, and elevated IL-12p40 secretion. This maturation reduced endocytic capacity but enhanced the allogenic stimulatory activity of the chicken MoDCs. …”
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6999
REPEATED THERAPEUTIC LEUKAPHERESIS - A SOLE TREATMENT DURING PREGNANCY AS A BRIDGE BEFORE TYROSINE KINASE INHIBITORS FOR A PREGNANT WOMAN WITH CHRONIC MYELOGENOUS LEUKEMIA – A CASE...
Published 2025-01-01“…Materials and Methods:A 20-year-old female patient, during a routine examination for pregnancy, presented with elevated white blood cells (WBC) count (over 275x109/L) and splenomegaly without any complaints. …”
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7000
Investigating the role of cathepsins in breast cancer progression: a Mendelian randomization study
Published 2025-01-01“…Within the human lysosomal system, a class of enzymes known as cathepsins exhibit elevated expression levels in various malignant tumors, suggesting that they may play key roles in cancer progression.MethodsThis study employed the two-sample Mendelian randomization (MR) approach to investigate the potential causal relationship between cathepsin levels and the risk of developing breast cancer. …”
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