Incidence of seroma and postoperative complications after breast surgery before and during the Covid-19 pandemic: results from a retrospective multicenter analysis by Maximilian Heinz Beck, Izabela A. Brachaczek, Pimrapat Gebert, Jens-Uwe Blohmer, Askin C. Kaya, Julia S. M. Zimmermann, Julia C. Radosa, Maria M. Karsten

“…Conclusion While our findings did not indicate an elevated incidence of seroma during the SARS-CoV-2 pandemic, we observed increased rates of erythema, wound healing disorders, and wound infection. …”
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Deficiency of purinergic P2Y2 receptor impairs the recovery after renal ischemia-reperfusion injury and accelerates renal fibrosis and tubular senescence in mice by Kyuho Jeong, Jihyun Je, Theodomir Dusabimana, Jacques Karekezi, Tatang Aldi Nugroho, Edvard Ntambara Ndahigwa, Hyun Joon Kim, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park

“…Renal apoptosis and inflammation were highly elevated in KO mice. Interestingly, cell proliferation as shown by Ki-67 and PCNA expression, was increased for 3 days after IR in WT mice, whereas it maintained increased for 14 days in KO mice. …”
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Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview by Maciej Rutkiewicz, Sabina Przygodzka, Katarzyna Gadżała, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“…Moreover, it is necessary to quit smoking, increase physical activity, and reduce cholesterol, elevating products from diet such as saturated fats and alcohol. …”
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Diagnostic ability of myxovirus resistance-A in pediatric cases of viral-acute respiratory tract infections with vitamin A and zinc deficiencies by Dian Kesumapramudya Nurputra, Amalia Setyati, Nur Arfian, Endy Paryanto Prawirohartono, Zulvikar Syambani Ulhaq

“…Our findings revealed that subjects with ARTI displayed elevated MxA expression compared to controls. Specifically, MxA expression levels in ARTI cases of viral origin were significantly higher than those in both control and bacterial origin. …”
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Exploring the impact of insufficient thermal ablation on hepatocellular carcinoma: NDST2 overexpression mechanism and its role in facilitating growth and invasion of residual cance... by Weijun Wan, Danxia Guo, Tong Kang, Jinshu Pang, Yunjing Pan, Jiamin Chen, Wei Liao, Yuji Chen, Peng Lin, Lipeng Li, Hong Yang, Yun He

“…Additionally, NDST2 was knocked down in heat stress-induced HCC cells, and the effects of NDST2 on these cells were verified using Cell Counting Kit-8 assays, scratch assays, and Transwell assays.Results NDST2 expression levels are elevated in HCC, leading to a decrease in overall survival rates of HCC patients. …”
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Alpha/beta values in pediatric medulloblastoma: implications for tailored approaches in radiation oncology by Danny Jazmati, Dennis Sohn, Juliane Hörner-Rieber, Nan Qin, Edwin Bölke, Jan Haussmann, Rudolf Schwarz, Niklas David Niggemeier, Arndt Borkhardt, Florian Babor, Triantafyllia Brozou, Melissa Felek, Balint Tamaskovics, Patrick Melchior, Thomas Beez, Beate Timmermann, Marc Remke, Stefanie Corradini, Rémi Till Schulz, Ronja-Linda Preugschas, Wilfried Budach, Christiane Matuschek

“…Results The study unveiled elevated alpha/beta ratios across diverse medulloblastoma cell lines, with a weighted mean alpha/beta value of 11.01 Gy (CI: 5.23–16.79 Gy). …”
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Muscular Performance and Blood Pressure After Different Pre-Strength Training Strategies in Recreationally Strength-Trained Women: Cross-Over Trial by Estêvão Rios Monteiro, Linda S. Pescatello, Luis Leitão, Marcelo José Colonna de Miranda, Paulo H. Marchetti, Michelle Ribeiro Novaes, Gleisson da Silva Araújo, Victor Gonçalves Corrêa Neto, Jefferson da Silva Novaes

“…However, these strategies indicated a clinical reduction in BP with a large and meaningful magnitude (effect size) in recreationally strength-trained women with normal to elevated BP. Conclusions: The results of this investigation may help to influence decision-making by practitioners who desire to elicit a post-exercise hypotension response in both subjects with normal BP and hypertension.…”
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Supra-Acetabular Brown Tumor due to Primary Hyperparathyroidism Associated with Chronic Renal Failure by Rosaria M. Ruggeri, Emanuele Calamoneri, Antonia Russo, Alessandro Sindoni, Baldassarre Mondello, Maurizio Monaco, Michele A. Rosa, Sergio Baldari, Salvatore Benvenga, Alfredo Campennì, Francesco Trimarchi

“…Serum intact PTH was elevated (1020 pg/ml; normal values, 12 62 pg/ml), but her serum calcium was normal (total = 9.4 mg/dl, nv 8.5–10.5; ionized = 5.0 mg/dl, nv 4.2–5.4) due to the coexistence of chronic renal failure. 99mTc-MIBI scintigraphy revealed a single focus of sestamibi accumulation in the left retrosternal location, which turned out to be an intrathoracic parathyroid adenoma at surgical exploration. …”
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The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells by Shuhd Bin Eshaq, Jalal Taneera, Shabana Anjum, Abdul Khader Mohammed, Mohammad H. Semreen, Karem H. Alzoubi, Mohamed Eladl, Yasser Bustanji, Eman Abu-Gharbieh, Waseem El-Huneidi

“…RNA-seq data analysis confirmed the expression of AHR in human islets, with elevated levels observed in pancreatic islets obtained from diabetic and obese donors compared to non-diabetic or lean donors. …”
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Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation by Qian-Lu Wang, Lei Yang, Yue Peng, Min Gao, Ming-Shi Yang, Wei Xing, Xian-Zhong Xiao

“…Ginsenoside Rg1 treatment remarkably suppressed apoptosis rate of LPS-induced A549 cells, relieved mouse lung tissue damage, and elevated survival rate. Rg1 treatment also rescued cells from LPS-induced intracellular ROS. …”
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Sodium arsenite induces islets β-cells apoptosis and dysfunction via SET-Rac1-mediated cytoskeleton disturbance by Tianming Qiu, Yu Zhi, Jingyuan Zhang, Ningning Wang, Xiaofeng Yao, Guang Yang, Liping Jiang, Li Lv, Xiance Sun

“…In addition, we detected cytoskeletal disorganization following NaAsO2 treatment, characterized by elevated Cofilin-1 protein expression (approximately 2.5-fold) and disrupted cytoskeleton arrangement. …”
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Pan-caspase inhibitor protects against noise-induced hearing loss in a rodent model by Maria Fernanda Yepes, Kayla Minesinger, Federica M. Raciti, Maria Camila Salazar, Suhrud M. Rajguru, Suhrud M. Rajguru, Suhrud M. Rajguru

“…Underlying mechanisms behind NIHL include elevated reactive oxygen species and inflammation, all which ultimately lead to cellular apoptosis. …”
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Utilizing Invasive <i>Pterygoplichthys pardalis</i> as a Sustainable Fish Meal Substitute and <i>Euphorbia hirta</i> Extract Supplement: Effects on Growth Performance, Organosomati... by Sontaya Sookying, Phanit Srisuttha, Vipada Rodprasert, Chanthima Chaodon, Wikit Phinrub, Nantaporn Sutthi, Paiboon Panase

“…The 50%+ and 75%+ PPM replacement groups exhibited significantly elevated serum glucose levels (<i>p</i> < 0.05). Liver enzymes (alanine transaminase and aspartate transaminase) showed no significant variations among the treatments. …”
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Monocyte to High‐Density Lipoprotein Ratio Is Associated With Carotid Plaque: A Retrospective Cohort Study by Shuang Liu, Xinlei Miao, Manling Hu, Ziping Song, Xiaoling Xie, Yuting Sun, Meng Li, Guimin Tang, Song Leng

“…Meanwhile, similar results were observed in multiple sensitivity analyses. Conclusions Elevated MHR was associated with the risk of CP. The assessment and management of MHR is helpful for the early detection of patients with CP and the primary prevention of cardiovascular diseases.…”
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Accelerated aging as a mediator of the association between co-exposure to multiple air pollutants and risk of chronic kidney disease by Shuo Zhang, Yuxin Liu, Jike Qi, Yu Yan, Tongyu Gao, Xin Zhang, Dong Sun, Ting Wang, Ping Zeng

“…The results showed that per interquartile range (IQR) increment in air pollution score led to an approximately 9.0 % (6.6–11.4 %) elevated risk of occurring CKD. Compared to the first quartile (Q1) of air pollution score, those in the highest quartile (Q4) had a 21.2 % (14.8–27.9 %) higher risk of developing CKD (Ptrend<0.001). …”
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Degradation Kinetics of Ascorbic Acid in Xanthan Gum Solution by Runqi JIA, Yujie TANG, Weiwei HE, Xiaoxiao SONG, Junyi YIN

“…Particularly, the degradation rate of AA, which was originally 7.03% in the absence of XG, increased to 11.72% when 0.2%XG (w/v) was present in the system at a concentration of 1 mmol/L. In addition, elevated reaction temperature accelerated the reaction between AA and XG, leading to a degradation rate of AA increased to 45.59% after heating at 90 ℃for 1 h. …”
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Short-term effects of follicle-stimulating hormone on immune function, lipid, and vitamin metabolism in transiently castrated men by Jéssica Guedes, Indira Pla, Aniel Sanchez, Gyorgy Marko-Varga, Gilberto Barbosa Domont, K Barbara Sahlin, Berk Hazir, Aleksander Giwercman, Fábio César Sousa Nogueira, Johan Malm, Yvonne Lundberg Giwercman

“…Background: Prostate cancer therapy with surgical or chemical castration with gonadotropin-releasing hormone (GnRH) agonists has been linked to elevated follicle-stimulating hormone (FSH) levels, which may contribute to secondary health disorders, including atherosclerosis and diabetes. …”
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Volatile Organic Compounds as Biomarkers of Gastrointestinal Diseases and Nutritional Status by Mariangela Rondanelli, Federica Perdoni, Vittoria Infantino, Milena Anna Faliva, Gabriella Peroni, Giancarlo Iannello, Mara Nichetti, Tariq A. Alalwan, Simone Perna, Clementina Cocuzza

“…In particular, C15H30 1-pentadecene, 3-methyl-1-butanal, octane, acetic acid, alpha-pinene, and m-cymene are elevated in active ulcerative colitis. Four studies examined VOCs in gastric and colorectal tumors showing a change in metabolic biomarkers of cancer patients compared to the control group. …”
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Use of a microvascular anastomotic coupler device for kidney transplantation in rats by Henrik Lauer, Jana Ritter, Patrick Nachtnebel, Kathrin Simmendinger, Emily Lerchbaumer, Vladyslav Kavaka, Dominik Steiner, Jonas Kolbenschlag, Adrien Daigeler, Johannes C. Heinzel

“…Early postoperative serum creatinine levels were slightly elevated about references thresholds, which normalized by postoperative day 3. …”
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Interaction between Angiotensin II and Insulin/IGF-1 Exerted a Synergistic Stimulatory Effect on ERK1/2 Activation in Adrenocortical Carcinoma H295R Cells by An-li Tong, Fen Wang, Yun-ying Cui, Chun-yan Li, Yu-xiu Li

“…Insulin (100 nM) or IGF-1 (10 nM) alone raised phospho-ERK1/2 1.8- and 1.5-fold, respectively, while, after pretreatment with 100 nM Ang II for 30 min, insulin (100 nM) or IGF-1 (10 nM) elevated phospho-ERK1/2 level 8- and 7-fold, respectively. …”
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