Genomic identification, evolutionary analysis, and transcript profiling of protein phosphatase 2C in Solanum lycopersicum by Miah Mohammad Sakib, Md. Sifatul Islam, Asifur Rob Bhuya, Md. Rihan Kabir Shuvo, Mohammad Abdullah-Al-Shoeb, Muhammad Abul Kalam Azad, Ajit Ghosh

“…Gene expression analysis revealed elevated transcript levels of SlPP2C22, SlPP2C30, and SlPP2C52 during drought stress. …”
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Behavior of unconfined steel-fiber reinforced UHPC post high-temperature exposure by Sohit Agrawal, Erika Yulianti, Mugahed Amran, Chung-Chan Hung

“…Simultaneously, levels of calcium silicate hydrate and calcium carbonate rose, indicating continued hydration at elevated temperatures. SEM imaging exposed significant microstructural issues at 300 ˚C, including debonding between fibers and the matrix, alongside microcracking and degradation at the aggregate-cement paste interface. …”
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Understanding neurocognitive recovery in older adults after total hip arthroplasty—neurocognitive assessment, blood biomarkers and patient experiences: a mixed-methods study by Ulrica Nilsson, Karin Liander, Lina Bergman, Anahita Amirpour, Jeanette Eckerblad, Gabriela Markovic

“…Psychological factors, including a sense of agency and low mood, significantly influenced cognitive recovery and daily functioning. Elevated inflammatory blood biomarkers were not detected pre- or postoperatively in patients with delayed neurocognitive recovery. …”
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Serum VEGF: Diagnostic Value of Acute Coronary Syndrome from Stable Angina Pectoris and Prognostic Value of Coronary Artery Disease by Anan Huang, Xin Qi, Yameng Cui, Yulin Wu, Shiqi Zhou, Mingyin Zhang

“…Although the level of serum vascular endothelial growth factor (VEGF) is elevated in coronary artery disease (CAD) patients, its potential role in acute coronary syndrome (ACS) or stable angina pectoris (SAP) patients remains unclear. …”
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Disulfidptosis-related lncRNA signature to assess the immune microenvironment and drug sensitivity in acute myeloid leukemia by Yuying Zhao, Hai-en Cheng, Jingfei Wang, Yunke Zang, Zhijun Liu, Yanhua Sun, Yanli Sun

“…Patients with high-risk AML evaluated based on the model had shorter survival, significant infiltration of monocytes and M2 macrophages, and elevated transcriptional levels of immune checkpoint genes. …”
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Risk of Subclinical Hypothyroidism in Breast Cancer Patients Treated With CT-Guided Radiation Therapy: A Prospective Observational Study by Amdisen L, Brink C, Lorenzen EL, Roenlev JD, Ewertz M, Cronin-Fenton D

“…However, a trend was observed suggesting that higher mean radiation dose to the thyroid was associated with elevated risk of subclinical hypothyroidism at a TSH threshold of > 2.5mIU/l.Conclusion: Using current reference levels, increasing radiation dose to the thyroid was not associated with subclinical hypothyroidism, but at lower TSH thresholds, radiation therapy may predispose to hypothyroidism.Keywords: breast neoplasms, radiotherapy, hypothyroidism, thyroid gland…”
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Continuous Consumption of Reused Palm Oil Induced Hepatic Injury, Depletion of Glutathione Stores, and Modulation of Cytochrome P450 Profiles in Mice by Waranya Chatuphonprasert, Yollada Sriset, Kanokwan Jarukamjorn

“…The expression profiles of drug-metabolizing CYPs were significantly modulated; Cyp2c29, Cyp3a11 , and Cyp3a13 were suppressed by both fresh and reused oil, while only the reused oil elevated Cyp2e1 . The expression of Cyp4a10 and Cyp4a14 , the key enzymes in lipid metabolism, were expectedly up-regulated by both. …”
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Chemical Characterization of Sub-micron Aerosols during New Particle Formation in an Urban Atmosphere by Vijay P. Kanawade, Sachchida N. Tripathi, Abhishek Chakraborty, Huan Yu

“…Moreover, the increased proportion of organic ions, m/z 44 (CO2+), on these days suggested the presence of less volatile, highly oxidized OAs (LV-OOAs), revealing that the growth of new particles was mainly due to the condensation of low-volatility organic species. The substantially elevated signal intensity of amines (viz., CHN+, CH4N+, C2H4N+, C3H8N+, and C5H12N+) in the sub-micron aerosols during NPF further demonstrated that these nitrogen-containing organic compounds may have played a critical role in these events. …”
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Relationship between Body Roundness Index and Risk of Type 2 Diabetes in Japanese Men and Women: A Reanalysis of a Cohort Study by Wei Zhao, Jingjing Tong, Jinghua Li, Yongtong Cao

“…BRI was positively linearly associated with an elevated risk of incident T2DM in women. In men, the relationship between BRI and T2DM was J-shaped. …”
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Assessment of sleep problems in patients with Kawasaki disease: a survey-based study by Samar Tharwat, Mohammed Kamal Nassar

“…KD patients exhibited significantly elevated scores in sleep onset delay, sleep duration, night wakings, parasomnias, and sleep-disordered breathing (p < 0.001). …”
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Impact of pre-pregnancy body mass index on preeclampsia by Jing Mao, Hanxiang Sun, Qinxin Shen, Chang Zou, Yuanyuan Yang, Qiaoling Du

“…After adjusting for confounding factors, the elevated risk of preeclampsia persisted, showing ORs of 2.152(95%CI, 1.911–2.425) for the overweight population and 3.493 (95%CI, 2.874–4.245) for those who were obese, while the risk for underweight women remained lower, with an OR of 0.609(95%CI, 0.511–0.727). …”
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Effects of exercise training on nigrostriatal neuroprotection in Parkinson’s disease: a systematic review by Shahid Ishaq, Iqbal Ali Shah, Shin-Da Lee, Shin-Da Lee, Bor-Tsang Wu

“…It also inhibited the ASC and NLRP3 inflammasome complex and reduced the BAX/ Bcl-2 ratio and caspase-1/3 proteins, thereby decreasing neuronal apoptosis in the nigrostriatum. Exercise training elevated the expression of Pro-BDNF, BDNF, GDNF, TrkB, and Erk1/2, providing neurotrophic support to dopaminergic neurons. …”
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Escherichia coli in septic arthritis: prevalence and antibiotics susceptibility patterns by Masroora Ali Khan, Muhammad Kamran Taj, Zahid Khan, Imran Taj, Muhammad Naeem, Saima Azam

“…Suspected patients showed a significant increase in the levels of white blood cells (WBC), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR), notably, these levels were further elevated in E. coli-positive patients. The polymerase chain reaction (PCR) based identification of E. coli showed clear bands of 204bp of the 16S rRNA gene. …”
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Operativity of the Taunsa Barrage, Pakistan: Experimental Investigation on the Subsidiary Weir by Muhammad Zahid Ullah, Habib-Ur-Rehman Mughal, Noor Yaseen, Noor Muhammad Khan, Giada Varra, Luca Cozzolino, Renata Della Morte

“…Phase 1 replicated the Taunsa Barrage before rehabilitation, assessing the need for SW construction under different discharge rates and downstream bed elevations. Phase 2 reproduced the post-rehabilitation conditions, including varying discharge values, heights and positions of the SW, to evaluate the stilling basin design concerning the ability to dissipate flow energy. …”
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Impact of different pathogen classes on the serum N-glycome in septic shock by Helena Torpy, The Huong Chau, Sayantani Chatterjee, Anastasia Chernykh, David J. Torpy, Emily J. Meyer, Morten Thaysen-Andersen

“…Aberrant serum N-glycosylation features were observed in patients with fungal infection relative to the other infection sub-groups including i) altered expression of prominent α2,6-sialylated biantennary N-glycan isomers, ii) elevated levels of IgG-type N-glycosylation and iii) a global shift in the serum N-glycome involving altered glycan type distribution and considerable changes in core fucosylation and α2,6-sialylation. …”
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The Effect of Vitamin D3 on Serum Creatine Phosphokinase Level in Patients with Multiple Trauma: A Pilot Randomized Clinical Trial by Mehran Kouchek, Niloufar Taherpour, Mahya Farasat, Mirmohammad Miri, Sara Salarian, Seyedpouzhia Shojaei, Rezvan Hassanpour, Hossein Amini, Mohammad Sistanizad

“…Conclusion: The current study revealed that vitamin D3, could prevent the increasing trend of CPK during the first days and accelerate the normalization of CPK in patients with elevated CPK due to multiple trauma.Trial registration number: IRCT20120703010178N23.…”
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Increased Growth Differentiation Factor 15 Levels Are Associated with HIV-Associated Neurocognitive Impairment: A Pilot Study by Ali Boustani, Mary K. Ford, Jacqueline R. Kulbe, Anna E. Laird, Leeann Shu, Matthew Spencer, Bryant Avalos, Kyle C. Walter, Ronald J. Ellis, Jerel Adam Fields

“…GDF15 protein levels were significantly elevated in the frontal cortices of PWH with NCI compared to NUI PWH. …”
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The Wnt/β-Catenin Pathway Regulated Cytokines for Pathological Neuropathic Pain in Chronic Compression of Dorsal Root Ganglion Model by Ye Zhang, Dan Zhao, Xutong Li, Beiyao Gao, Chengcheng Sun, Shaoting Zhou, Yanhong Ma, Xuemei Chen, Dongsheng Xu

“…Furthermore, we found that the levels of proinflammatory factors tumor necrosis factor-α (TNF-α) and interleukin-18 (IL-18) were significantly elevated in CCD rat serum, while the levels of them were correspondingly decreased after the Wnt/β-catenin pathway being inhibited. …”
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SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation by Ryan T. Wagner, Ryan A. Hlady, Xiaoyu Pan, Liguo Wang, Sungho Kim, Xia Zhao, Louis Y. El Khoury, Shafiq Shaikh, Jian Zhong, Jeong-Heon Lee, Jolanta Grembecka, Tomasz Cierpicki, Thai H. Ho, Keith D. Robertson

“…Depletion of NSD1 using a CRISPRi targeting approach promotes the loss of SETD2-mutant cells coincident with elevated levels of DNA damage and apoptosis. Surprisingly, only suppression of NSD1, but not related H3K36-methyltransferases, promotes synthetic lethality in these models. …”
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Frequent Detection of Anti-Tubercular-Glycolipid-IgG and -IgA Antibodies in Healthcare Workers with Latent Tuberculosis Infection in the Philippines by Umme Ruman Siddiqi, Prisca Susan A. Leano, Haorile Chagan-Yasutan, Beata Shiratori, Hiroki Saitoh, Yugo Ashino, Yasuhiko Suzuki, Toshio Hattori, Elizabeth Freda O. Telan

“…The titers of TBGL-IgA were associated with serum IgA (P=0.02) in HIV-AC. Elevations of TBGL-IgG and -IgA were related to latent tuberculosis infection in HCWs, but careful interpretation is necessary in HIV-AC.…”
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