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6721
Stereotactic body radiation therapy for hepatocellular carcinoma: Practice patterns, dose selection and factors impacting survival
Published 2019-03-01“…On multivariate analysis, low BED (<75 Gy, HR 2.537, P < 0.001; 75‐100 Gy, HR 1.986, P = 0.007), increasing tumor size (HR 1.067, P = 0.032), elevated AFP (HR 1.585, P = 0.019), stage 3 (HR 1.962, P < 0.001), low‐volume facilities (1‐5 cases HR 1.687, P = 0.006), and a longer time interval from diagnosis to SBRT (>2 to ≤4 months, HR 1.456, P = 0.048; >4 months, HR 2.192, P < 0.001) were associated with worse survival. …”
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6722
In Vitro Induction of Hypertrophic Chondrocyte Differentiation of Naïve MSCs by Strain
Published 2024-12-01“…This was demonstrated by increased cell volumes and reduced glycosaminoglycan (GAG) production, along with an elevated expression of hypertrophic markers such as MMP13 and Type X collagen. …”
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6723
Association between C-reactive protein and chronic pain in US adults: A nationwide cross-sectional study.
Published 2025-01-01“…Individuals exhibiting elevated levels of CRP demonstrated a heightened propensity for experiencing chronic pain in comparison to individuals with lower CRP levels. …”
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6724
A bidirectional Mendelian randomization study integrating genome-wide association studies, expression quantitative trait locus, and methylation quantitative trait locus data reveal...
Published 2025-02-01“…Inverse variance-weighted methods of bidirectional Mendelian randomization also revealed that smoking per day was significantly associated with elevated risks of Barrett’s esophagus (odds ratio = 1.34, 95% confidence interval: 1.092–1.649, p = 0.005), while Barrett’s esophagus was also a susceptibility factor for smoking per day (odds ratio = 1.05, 95% confidence interval: 1.017–1.087, p = 0.003). …”
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6725
Analysis of Multifrequency GNSS Signals and an Improved Single-Epoch RTK Method for Medium-Long Baseline
Published 2023-01-01“…Second, the fixed WL ambiguities of Galileo and BDS are exploited to elevate the fixed rate of GPS WL ambiguity. Third, the parametric strategies for ionospheric delay are carried out to upregulate the narrow-lane (NL) ambiguity-fixed rate of GPS. …”
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6726
Effect of drying methods on phenolic compounds and antioxidant activity of Capparis spinosa L. fruits
Published 2025-01-01“…Drying at 600 W microwave yielded the highest levels of caffeic, cinnamic, ferulic, vanillic, and protocatechuic acids (13.03, 3.85, 4.28, 9.73, and 5.6 µg/g, respectively) while drying at 900 W microwave also resulted in elevated levels of caffeic, ferulic, protocatechuic, and p-coumaric acids. …”
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6727
Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells
Published 2025-01-01“…Conversely, iPSC-SC NSPCs displayed significant heterogeneity, suboptimal regional specification, and elevated expression of neural crest and immune response-associated genes. …”
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6728
Biological functions of extracellular vesicle double C2-like domain beta in cervical cancer
Published 2025-01-01“…Co-culture of SiHa and HeLa cells with DOC2B-SiHa derived EVs induced morphological changes and suppressed their growth and migration, possibly by induction of G0/G1 to S phase arrest and anoikis. DOC2B-SiHa EVs elevated intracellular reactive oxygen species (ROS) and calcium levels and promoted lipid droplet accumulation and lipid peroxidation rate in recipient cells. …”
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6729
Exploring the Predictive Role of 11‐Oxyandrogens in Diagnosing Polycystic Ovary Syndrome
Published 2025-01-01“…Results Total testosterone, androstenedione, and four 11‐oxyandrogens were significantly elevated in women with PCOS compared to age matched controls, controlling for age and BMI (p < 0.01 for all). …”
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6730
Interaction of Hypertension and Insulin Resistance Exacerbates the Occurrence of Diabetes Mellitus in Healthy Individuals
Published 2022-01-01“…When hypertension was combined with insulin resistance (HOMA-IR ≥2.68), the risk of newly diagnosed diabetes was 38.32 times compared with the control group [OR: 38.315, 95% CI 9.227-159.108, P<0.001]. Conclusions. Elevated blood pressure levels and insulin resistance levels were associated with the risk of newly diagnosed diabetes. …”
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6731
Serum Levels of SDF-1 and CXCR4 in Breast Cancer: Correlation with Disease Progression and Chemotherapy Response in Iraqi Women
Published 2024-12-01“…Blood samples (3 ml) were collected, processed, and stored for analysis, with serum levels of SDF1 and CXCR4 measured using ELISA kits.The study revealed that SDF1 levels were significantly elevated in newly diagnosed patients (84.91 ± 4.2 pg/ml) compared to chemotherapy patients (59.94 ± 2.18 pg/ml) and controls (57.00 ± 3.47 pg/ml), with p≤0.001. …”
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6732
Characteristics of plastic bronchitis in children with infectious pneumonia
Published 2025-02-01“…Compared with those in the non-PB group, the number of patients with abnormally elevated of D-D dimer, LDH, ALT, and AST in the PB group was significantly greater. …”
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6733
Amelioration of Coagulation Disorders and Inflammation by Hydrogen-Rich Solution Reduces Intestinal Ischemia/Reperfusion Injury in Rats through NF-κB/NLRP3 Pathway
Published 2020-01-01“…Additionally, HRS attenuated inflammatory responses and the elevated tissue factor (TF) and inhibited nuclear factor kappa beta (NF-κB) and nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation in peripheral blood mononuclear cells. …”
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6734
Serum vascular endothelial growth factor levels as a marker of skin thickening, digital ischemia, and interstitial lung disease in systemic sclerosis
Published 2018-01-01“…Conclusion: Serum VEGF levels were elevated in SSc and they correlated with the severity of skin thickening, digital ischemia, and presence of ILD.…”
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6735
Influence of day and night temperature and carbon dioxide concentration on growth, yield, and quality of green butterhead and red oakleaf lettuce.
Published 2025-01-01“…'Rouxaï RZ' fresh mass increased quadratically with MDT, with a 32% increase from 20 to 23°C, then a 7% increase from 23 to 26°C. Elevating CO2 concentrations from 500 to 800 μmol·mol-1 increased 'Rouxaï RZ' and 'Rex' fresh mass by 33 and 16%, respectively, while fresh mass did not increase from 800 to 1200 μmol·mol-1. …”
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6736
RETRACTED: Efficacy of Vanadyl Sulfate and Selenium Tetrachloride as Anti-Diabetic Agents against Hyperglycemia and Oxidative Stress Induced by Diabetes Mellitus in Male Rats
Published 2021-12-01“…The findings show that the administration of VOSO<sub>4</sub> with selenium tetrachloride reduced oxidative stress to normal levels, lowered blood glucose levels, and elevated insulin hormone. Additionally, VOSO<sub>4</sub> with selenium tetrachloride had a synergistic effect and significantly decreased pancreatic genotoxicity. …”
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6737
Association between weight change across adulthood and risk of chronic kidney disease: NHANES 1999–2020
Published 2025-12-01“…Furthermore, stratified analyses were conducted to explore potential interactions between age, sex, and smoking status about CKD risk.Results The study found that individuals transitioning from obesity to non-obesity, non-obesity to obesity, and remaining stable obesity had an elevated risk of developing CKD throughout adulthood compared to those maintaining stable non-obesity weight patterns. …”
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6738
APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease
Published 2025-01-01“…We observed increased numbers of ApoE-positive astrocytes in the WM of both NCI and MCI APOEε4 carriers compared with non-carriers, whereas Fabp7-positive cells were elevated only in AD. Conversely, Olig2 cell counts and MBP immunostaining decreased in MCI APOEε4 carriers compared to non-carriers, while LFB levels were higher in NCI APOEε4 carriers compared to non-carriers. …”
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6739
The Prognostic Value of Total Blood Count Parameter Ratios in Acute Pulmonary Embolism
Published 2024-12-01“…The PLR showed no significant difference between risk groups (<i>p</i> = 0.233). An elevated NLR, PLR, and MPVLR correlated with ICU admission, intubation, and mortality (<i>p</i> < 0.001, <i>p</i> < 0.007, and <i>p</i> < 0.001, respectively). …”
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6740
Digital health technologies and self-efficacy in Parkinson’s: a scoping review
Published 2025-01-01“…Data was extracted from a Microsoft Excel spreadsheet and synthesised by describing themes, demographic data and numerical data.Results From 33 165 unique records following screening and independent review by two reviewers, 11 eligible records were found. Of these five elevated self-efficacy to a statistically significant level, five did not and one lowered self-efficacy. …”
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