The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues by Farnaz Sani, Mina Soufi Zomorrod, Negar Azarpira, Masoud Soleimani

“…Also, miR-17-5p expression was elevated in fibrosis conditions. Furthermore, we showed that our treatments decreased alanine aminotransferase and aspartate aminotransferase, and increased albumin levels in the culture supernatant. …”
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Elucidating the role of pyrimidine metabolism in prostate cancer and its therapeutic implications by Liang Huang, Yu Xie, Shusuan Jiang, Kan Liu, Zhihao Ming, Hong Shan

“…Drug sensitivity analysis further demonstrated that tumors with elevated pyrimidine metabolism displayed increased responsiveness to several chemotherapeutic agents, including BI-2536, JW-7-24-1, and PAC-1, suggesting that targeting pyrimidine metabolism may enhance treatment efficacy. …”
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Effect of Sechium edule extract on blood sugar levels and pancreatic histopathology in male Rats with type II diabetes mellitus by Marti Silfia, Gusbakti Rusip, Linda Chiuma, Ade Indra Mukti, Lia Restumulia

“…Diabetes mellitus (DM) is a metabolic disorder characterized by elevated blood glucose levels (hyperglycemia) and the presence of glucose in the urine (glucosuria). …”
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The association between dietary sodium density and Hashimoto’s thyroiditis in US adults by Peilin An, Silin Wang, Lingyun Liu, Xuelin Li, Xin Lv, Xin Lv

“…Higher sodium density was also associated with increased TPOAb positivity (OR 1.28, 95% CI 1.05–1.56), but not TgAb positivity.ConclusionElevated dietary sodium density is associated with an increased risk of HT and TPOAb positivity, suggesting that sodium intake may play a role in the pathogenesis of HT.…”
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卒中防治科学传播发展现状与对策建议的研究进展 Research Progress on the Development Status and Countermeasures of Scientific Communication in Stroke Prevention and Treatment... by 张熙1，李杨1，张鹏骞2，3 (ZHANG Xi1, LI Yang1, ZHANG Pengqian2,3 )

“…These research contents and findings contribute to further elevating the level of scientific communication in stroke prevention and treatment, providing a reference for the government, medical workers, and relevant departments in carrying out scientific communication in stroke prevention and treatment. …”
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A holistic physics-informed neural network solution for precise destruction of breast tumors using focused ultrasound on a realistic breast model by Salman Lari, Hossein Rajabzadeh, Mohammad Kohandel, Hyock Ju Kwon

“…By applying a 3.8 nm displacement amplitude of transducer input pulse at a frequency of 1.1 MHz for 1 second, the temperature at the focal point elevated to 38.4 ℃, followed by another 90 seconds of cooling time, which resulted in significant necrosis of the tumor tissues. …”
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Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: integration of bioinformatics and experimental validation by Guangtang Chen, Xueping Shi, Rukai Jiao, Jiacai Qian, Xiaolin Du, Jian Liu, Xi Zeng

“…Results NCOA4 expression was significantly elevated in LGG (p < 0.05), with an Area Under the Receiver Operating Characteristic Curve (AUC) of 0.973, suggesting it as a potential diagnostic marker. …”
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Massive Pulmonary Embolism Complicating Coronavirus Disease 2019 (COVID-19) Pneumonia: A Case Report by Shruti Hegde, Gemini Yesodharan, John Tedrow, Alena Goldman

“…On bedside TTE, there was evidence of right heart strain and elevated pulmonary artery systolic pressure of 45 mmHg. …”
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Assessing the salinization mechanisms of coastal brackish springs by Sanz, Esteban, Carrera, Jesús, Ayora, Carlos, Barón, Alfredo, González, Concha

“…The phenomenon is puzzling because these springs may discharge high flow rates with significant salinities at elevations of several meters above sea level. Although these springs have been studied for millennia (since the ancient Greeks), controversy persists. …”
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Le lieu-dit des « Trois-Piliers » : un ensemble à caractère monumental du iiie s. apr. J.-C. dans la périphérie nord-est de Reims/Durocortorum ? by Philippe Rollet, Émilie Jouhet

“…The place known as “Trois-Piliers” is located on one of the lower elevations, overlooking the city of Reims. It occupies the border of the northeastern quarter of the Early Empire city, delimited a few dozen meters to the north by the Augustan enclosure and located 250 m east of the Reims (Marne)-Bavay (Nord) road. …”
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Insulin autoimmune syndrome in a 3-year-old boy: the youngest to date in China and a narrow review by Ming Cheng, Yuan Ding, Dongmei Wang, Chunxiu Gong

“…Conclusion When differentiating the causes of HH in pediatric patients, IAS should not be overlooked. Elevated levels of IAAs and an inappropriate insulin to C-peptide molar ratio during an extended OGTT are critical indicators. …”
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Low-density Lipoproteins and Degrees of Cardiovascular Risk in Adults over 40 Years of Age: Case-control Study by Abel Pérez Pavón, Francisco Sánchez Hernández, Karla Doriam Gámez Ávalos, Donovan Casas Patiño, Alejandra Rodríguez Torres

“…<br /><strong>Results:</strong> the female gender was the most frequent, the average age was 62 years, elevated total cholesterol presented 109 (94.8) patients with high cardiovascular risk, an MRI was calculated: 43,279, CI: 95 %, ( 17,347-107,980), LDL cholesterol presented 68 % (59.1) with cardiovascular risk and an MRI: 1.28, CI: 95 % (0.760-2.158), the evaluation of triglycerides with high figures presented 50.4 % (58), OR: 0.037, 95 % CI (0.013-0.106). …”
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The composition of peripheral immunocompetent cell subpopulations and cytokine content in the brain structures of mutant Disc1-Q31L mice by M. M. Gevorgyan, S. Ya. Zhanaeva, E. L. Alperina, T. V. Lipina, G. V. Idova

“…Thus, Disc1-Q31L mice are characterized by changes in the pattern of cytokines in the brain structures, an amplification of the peripheral T-cell link with an increase in the content of the subpopulations of CD3+CD4+ T helpers and CD3+CD4+CD25+ T regulatory cells, as well as elevated immune reactivity to antigen in the spleen.…”
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Numerical computation of PDE formed characterizing thermal rheology of Cu/Al2O3/TiO2 ternary nanoparticles flow between coaxial cylinders by Noreen Sher Akbar, M.Fiaz Hussain, Dennis Ling Chuan Ching, Muhammad Farooq, Ilyas Khan

“…A decrease in shear stress occurs for expanding cases, while an increase in the thermal system is evident with rising nanoparticle concentrations. Elevated temperatures are observed with increased thermophoresis variables. …”
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The Effect of Prior Gestational Diabetes on the Shape of the Glucose Response Curve during an Oral Glucose Tolerance Test 3 Years after Delivery by Timea Tänczer, Márk M. Svébis, Beatrix Domján, Viktor J. Horváth, Adam G. Tabák

“…According to multiple logistic regression, MGR was associated with prior early GDM (OR 2.14, 95% CI 0.92-4.99) and elevated triglyceride levels (OR 2.28, 95% CI 1.03-5.03/log (mmol/l)). …”
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The fate and mobility of chromium, arsenic and zinc in municipal sewage sludge during the co-pyrolysis process with organic and inorganic chlorides by Mahboub Saffari, Masomeh Moazallahi, Rezvan Mashayekhi

“…In contrast, FeCl3 treatments exhibited elevated risk levels, especially at higher concentrations and temperatures, reaching moderate to considerable risk categories. …”
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Clinical characteristics of Kawasaki disease with pulmonary radiographic abnormalities and its impact on the incidence of coronary artery lesions: a randomized retrospective cohort... by Chenchen Liu, Xing Rong, Huixian Qiu, Jinhui Zhou, Yufei Chen, Xuhong Huang, Maoping Chu, Zhenquan Wang

“…In KD patients with pneumonia-like changes, there were significant elevations in inflammatory markers including the C-reactive protein (CRP) (P = 0.011), white blood cell (WBC) (P = 0.027), NT-proBNP (P = 0.007), and D-dimer (D-D) (P = 0.002) levels. …”
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L-Borneol 7-O-[β-D-Apiofuranosyl-(1→6)]-β-D-Glucopyranoside Alleviates Myocardial Ischemia-Reperfusion Injury in Rats and Hypoxic/Reoxygenated Injured Myocardial Cells via Regulati... by Ziyi Tong, Gaowen Li, Chengxiao Su, Liyan Zhou, Ling Zhang, Qun Chen, Qing Xia

“…In H/R-induced H9c2 cells, LBAG pretreatment significantly decreased cell apoptosis, LC3 II/I, and Beclin 1 levels, elevated the Bcl-2 levels, attenuated LDH, and CD-KM production. …”
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Evaluation of diastole by echocardiography for detecting early cardiac dysfunction: an outcome study by Tatiana Kuznetsova, Nicholas Cauwenberghs, František Sabovčik, Yukari Kobayashi, Francois Haddad

“…In contrast, the adjusted risks of adverse cardiac events (HR = 1.28; P = 0.0045) were significantly elevated in participants with LVDDF when classified according to the population‐derived criteria. …”
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Development and Characterization of Chitosan Nanoparticles Loaded with Amoxicillin as Advanced Drug Delivery Systems against Streptococcus Mutans by Abdullah J Jasem, Maha A Mahmood

“…MS colonies on MSBA plates were blue, spherical or ovoid, 1-2 mm in diameter, with elevated surfaces that stuck well to the agar. Rough colonies had a rough or frosted glass surface. …”
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