Spondias purpurea L. (Anacardiaceae) fruits flours at different maturation stages: Drying kinetics, mathematical modelling, characterization and correlation analysis by Álvaro Gustavo Ferreira da Silva, Franciscleudo Bezerra da Costa, Ana Marinho do Nascimento, Giuliana Naiara Barros Sales, Jéssica Leite da Silva, Alzira Maria de Sousa Silva Neta, Wellington Souto Ribeiro, Toshik Iarley da Silva, Bruno Fonsêca Feitosa

“…Immature fruits yielded flours with elevated titratable acidity, total chlorophylls, phenolic compounds, and density. …”
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Combined exposure to mixed brominated flame retardants on obstructive sleep apnea syndrome in US adults by Junping Liu, Zhaoyue Liu, Xinru Liu, Nan Wang, Lin Wu, Xiaoxue Xu, Wei Liu, Yajie Feng, Huanyu Zhang, Yue Zhou, Xinle Yin, Yaping Liu, Qunhong Wu, Ning Ning, Libo Liang

“…Abstract Background Accumulating research highlights that exposure to serum brominated flame retardants (BFRs) may elevate health risks. The effects of serum BFRs, both alone and in combination, on obstructive sleep apnea syndrome (OSAS) have not been thoroughly studied. …”
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Acute effects of physical exercise on cognitive function and neurotrophins in patients with type 1 diabetes: A systematic review by Emanuele Zanardo, Giulia Quinto, Francesca Battista, Federica Duregon, Marco Vecchiato, Chiara Bergia, Kirk Erickson, Andrea Ermolao, Daniel Neunhaeuserer

“…Physical exercise has been associated with elevated levels of BDNF and consequently improved cognitive function, but whether this association is found in T1DM remains unresolved. …”
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Wild pea (<i>Pisum sativum</i>Pisum sativum L. subsp. <i>elatius</i> (Bieb.) Aschers. et Graebn. s.l.) at the periphery of its range: Zagros Mountains by O. E. Kosterin, V. S. Bogdanova, A. V. Mglinets

“…A two-week-long expedition to Iran in May 2017 revealed two small populations of the wild pea (Pisum sativum subsp. elatius) in the Zagros Mts, in Aligudarz and Khorramabad Districts of Lorestan Province, Iran, at elevations of 1841 and 1971 m a.s.l., respectively. …”
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Rationale and design of a randomized clinical trial of integrated eHealth for PrEP and medications for opioid use disorders for women in the criminal legal system. The Athena study by Jaimie P. Meyer, Stacey Brunson, Carolina R. Price, Morgan Mulrain, Julie Nguyen, Frederick L. Altice, Tassos C. Kyriakides, Karen Cropsey, Ellen Eaton

“…Abstract Background Women involved in the criminal legal system have elevated rates of opioid use disorder, which is treatable, and HIV, which is preventable with pre-exposure prophylaxis (PrEP). …”
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Effects of genetic ablation and pharmacological inhibition of HuR on gene expression, iron metabolism, and hormone levels by Nathalie Idlin, Sivakumar Krishnamoorthy, Magdalena Wolczyk, Mouad Fakhri, Michal Lechowski, Natalia Stec, Jacek Milek, Pratik Kumar Mandal, Jaroslaw Cendrowski, Christos Spanos, Magdalena Dziembowska, Katarzyna Mleczko-Sanecka, Juri Rappsilber, Gracjan Michlewski

“…Abstract Background HuR/ELAV1, a ubiquitous RNA-binding protein, belongs to the RNA-binding protein family and is crucial for stabilizing and regulating the translation of various mRNA targets, influencing gene expression. Elevated HuR levels are associated with multiple disorders, including cancer and neurodegenerative diseases. …”
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The Potential Applications of Stem Cell Conditioned Medium Secretome in Knee Cartilage Regeneration: A Systematic Review by I Gusti Ngurah Wien Aryana, Febyan Febyan, Nyoman Gede Grenata Nanda Ustriyana

“…Synovial membrane-derived MSCs significantly enhanced cartilage regeneration by elevating chondrogenic capabilities. Hydrogel-based systems techniques and 3D-printed scaffolds have emerged for innovative delivery. …”
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Single Exposure to Low-Intensity Focused Ultrasound Causes Biphasic Opening of the Blood-Brain Barrier Through Secondary Mechanisms by Tasneem A. Arsiwala, Kathryn E. Blethen, Cullen P. Wolford, Geoffrey L. Pecar, Dhruvi M. Panchal, Brooke N. Kielkowski, Peng Wang, Manish Ranjan, Jeffrey S. Carpenter, Victor Finomore, Ali Rezai, Paul R. Lockman

“…<b>Results:</b> Our findings show that LiFUS significantly increased vascular volume and glucose uptake, with reduced P-gp function in brain tissues six hours post treatment, indicating biphasic BBB disruption. Additionally, elevated levels of pro-inflammatory cytokines, including TNF-α and IL-6, were observed in both sonicated and non-sonicated regions. …”
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Effects of aminooxyacetic acid on learning and memory function and neurochemical changes in chronic alcoholism by Hongbo Jiang, Xunling Wang, Yingwei Liang, Yinghan Hou, Xinping Yue, Zhiyi Zhang, Dan Chen, Xinyi Fan, Ailin Du

“…Results: Compared to the control groups, rats in the Model group exhibited significant impairments in learning and memory, increased CBS expression, elevated H₂S levels, and decreased 5-HT release. AOAA treatment improved memory performance, reduced CBS expression and H₂S levels, and increased 5-HT release, although these measures did not fully return to baseline. …”
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Correlation between Phase Angle and the Number of Medications in Older Inpatients: A Cross-Sectional Study by Toshiyuki Moriyama, Mizuki Tokunaga, Ryoko Hori, Akiko Hachisuka, Hideaki Itoh, Mitsuhiro Ochi, Yasuyuki Matsushima, Satoru Saeki

“…Background Muscle weakness in older adults elevates mortality risk and impairs quality of life, with the phase angle (PhA) indicating cellular health. …”
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Safety and effectiveness of dual therapy for Helicobacter pylori infection and the effect on the glycated hemoglobin level in type 2 diabetes by Jie Zhang, Xin Cao, Kai Ma, Yizhou Jiang, Xiangrong Qin, Xiaoyong Wang

“…The multivariate analysis revealed that the independent risk factors for H. pylori eradication failure were smoking (OR: 4.59, 95% CI: 1.20–17.58, p = 0.026) and elevated A1C level (OR: 1.65, 95% CI: 1.01–2.68, p = 0.044). …”
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Dietary Nannochloropsis oculata ameliorates lead acetate induced reproductive toxicity in Barki rams: NF-κB and cytokines pathways by Doaa H. Elsayed, Sameer A. Nagadi, Heba M.A. Abdelrazek, Ahmed. S. El‑Hawy, Moharram F. El-Bassiony, Seham A. Helmy, Yasmina K. Mahmoud, Ibrahim E. Helal, Shady T. Hassan

“…However, lead-treated rams showed significant deteriorations in semen criteria and reduced GSH while significant elevations in MDA, IL-4, IL-2 as well as gene expression of IL-6 and NF-κB were noticed than control. …”
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Pembrolizumab with external radiation therapy effectively controlled TMB-high unresectable recurrent parathyroid cancer: a case report with review of literature by Hiroshi Katoh, Tomoya Mitsuma, Riku Okamoto, Kanako Naito, Takaaki Tokito, Mariko Kikuchi, Takafumi Sangai

“…He was referred to our hospital due to persistent hypercalcemia and elevated PTH. The recurrent tumors were identified in the superior mediastinum and radically resected, then the hyperparathyroidism was improved. …”
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AquaCrop model-based sensitivity analysis of soil salinity dynamics and productivity under climate change in sandy-layered farmland by Zhuangzhuang Feng, Qingfeng Miao, Haibin Shi, José Manuel Gonçalves, Xianyue Li, Weiying Feng, Jianwen Yan, Dandan Yu, Yan Yan

“…The model simulations, calibrated with these sensitive parameters, indicated that under future climate change scenarios, maize yield is projected to increase by approximately 19 % by mid-21st century due to elevated CO2 concentrations and water productivity increasing by 22–27 %. …”
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FEN-MRMGCN: A Frontend-Enhanced Network Based on Multi-Relational Modeling GCN for Bus Arrival Time Prediction by Ting Qiu, Chan-Tong Lam, Bowie Liu, Benjamin K. Ng, Xiaochen Yuan, Sio Kei Im

“…Future research will focus on leveraging additional data sources and exploring advanced graph convolutional architectures to further elevate prediction accuracy.…”
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Investigating the response mechanisms of the intertidal seagrass Zostera japonica to increased UVB radiation through physiological, transcriptomic, and metabolomic analyses by Jiayi Xin, Song Xue, Hongzhen Wang, Xinqi Li, Yu Zang, Lei Liu, Xuexi Tang, Jun Chen

“…However, the specific response mechanisms of Z. japonica to elevated levels of UVB radiation are not fully understood. …”
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Real-world of Limosilactobacillus reuteri in mitigation of acute experimental colitis by Ningning Yue, Hailan Zhao, Peng Hu, Yuan Zhang, Chengmei Tian, Chen Kong, Zhiliang Mai, Longbin Huang, Qianjun Luo, Daoru Wei, Ruiyue Shi, Shaohui Tang, Yuqiang Nie, Yujie Liang, Jun Yao, Lisheng Wang, Defeng Li

“…Second, L. reuteri-CMVs were taken up by intestinal epithelial cells (IECs), elevated the expression of ZO-1, E-cadherin (Cdh1), and Occludin (Ocln), decreased intestinal permeability, and exerted protective effects on epithelial tight junction functionality. …”
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Adverse Reactions from Topical Ophthalmic Anesthetic Abuse by Ali Sharifi, Naser Naisiri, Majid Shams, Meraj Sharifi, Hamid Sharifi

“…Finally, 51.6% (n =16) of the eyes had decreased vision, 45.2% (n =14) had corneal opacity, 16.1% (n = 5) had elevated intraocular pressure that needed long-term anti-glaucoma therapy, and 6.5% (n = 2) had corneal pannus. …”
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Serum Levels of IL-1β, IL-6, TGF-β, and MMP-9 in Patients Undergoing Carotid Artery Stenting and Regulation of MMP-9 in a New In Vitro Model of THP-1 Cells Activated by Stenting by Rongrong Zhang, Fan Jiang, Cindy Si Chen, Tianzhu Wang, Jinzhou Feng, Tao Tao, Xinyue Qin

“…In our study, we first found that, after CAS, the serum IL-1β, IL-6, TGF-β, and MMP-9 levels were significantly increased, but only MMP-9 level was elevated no less than 3 months. Second, we established a new in vitro model, where THP-1 monocytes were treated with the supernatants of human umbilical vein endothelial cells (HUVECs) that were scratched by pipette tips, which mimics monocytes activated by mechanical injury of stenting. …”
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Increased positive tree species mixture effects on the abundance and richness of Collembola with stand development in Canadian boreal forests by Yakun Zhang, Sai Peng, Zilong Ma, Chen Chen, Bilei Gao, Xinli Chen, Han Y.H. Chen

“…We conclude that tree species mixtures can significantly enhance Collembola abundance and diversity, particularly in older stands and those with elevated soil nutrient levels.…”
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