Expert-Performed Endotracheal Intubation-Related Complications in Trauma Patients: Incidence, Possible Risk Factors, and Outcomes in the Prehospital Setting and Emergency Departmen... by Yuko Ono, Takeyasu Kakamu, Hiroaki Kikuchi, Yusuke Mori, Yui Watanabe, Kazuaki Shinohara

“…Multivariable logistic regression analysis revealed that low Glasgow Coma Scale Score (adjusted odds ratio [AOR], 0.93; 95% confidence interval [CI], 0.88–0.98), elevated heart rate (AOR, 1.01; 95% CI, 1.00–1.02), and three or more ETI attempts (AOR, 15.71; 95% CI, 3.37–73.2) were independent predictors of ETI-related complications. …”
Get full text

Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats by Yi-Wen Chien, Hsiang-Chi Peng, Ya-Ling Chen, Man-Hui Pai, Hsiao-Yun Wang, Hsiao-Li Chuang, Suh-Ching Yang

“…Hepatic thiobarbituric acid-reactive substance (TBARS) levels, cytochrome P450 2E1 protein expression, and tumor necrosis factor- (TNF-) α, interleukin- (IL-) 1β, IL-6, and IL-10 levels, as well as intracellular adhesion molecule (ICAM)-1 levels were significantly elevated, whereas plasma adiponectin level was significantly reduced in group E (p<0.05). …”
Get full text

Cervical Spinal Osteomyelitis with Epidural Abscess following an Escherichia coli Urinary Tract Infection in an Immunocompetent Host by Abdelmoniem Moustafa, Rowida Kheireldine, Zubair Khan, Hussam Alim, Mohammad Saud Khan, Mohd Amer Alsamman, Eslam Youssef

“…Lumbar puncture showed 94 RBCs, 24 WBCs (16% neutrophils and 46% lymphocytes), and elevated protein level at 1140 mg/dl with no bacteria. …”
Get full text

Serum Cytokines Th1, Th2, and Th17 Expression Profiling in Active Lupus Nephritis-IV: From a Southern Chinese Han Population by Keshav Raj Sigdel, Lihua Duan, Yin Wang, Weiping Hu, Ning Wang, Qingyi Sun, Qingyan Liu, Xiaocong Liu, Xianghua Hou, Ao Cheng, Guixiu Shi, Yanlin Zhang

“…Importantly, the ratios of Th1/Th2 (IL-18/IL-4) and Th17/Th2 (IL-17A/IL-4) were significantly elevated in LN-IV when compared with LN-III, LN-V, and healthy controls. …”
Get full text

Effect of long-term serum sodium levels on the prognosis of patients on maintenance hemodialysis by Siyu Chen, Bin Pan, Xiaowei Lou, Jianghua Chen, Ping Zhang

“…Finally, a total of 21,701 patients were included in this study and Cox regression showed that decreased SNa levels (Na < 135 mmol/L, HR = 1.704, 95% CI 1.408–2.063, p < 0.001; 135≦Na≦137.5 mmol/L, HR = 1.127,95% CI 1.016–1.250, p = 0.024) and elevated SNa levels (142.5 < Na≦145mmol/L, HR = 1.198, 95% CI 1.063–1.350, p = 0.003; Na > 145mmol/L, HR = 2.150, 95% CI 1.615–2.863, p < 0.001) were all independent risk factors for all-cause mortality in MHD patients.…”
Get full text

Twenty years’ experience of midgut malrotation and volvulus in a tertiary center in northern Taiwan: A retrospective study by Wen-Yu Tseng, Ming-Wei Lai, Jin-Yao Lai, Chien-Chang Chen, Hsun-Chin Chao, Jeng-Chang Chen, Shih-Yen Chen, Yung-Ching Ming, Hung-Yu Yeh, Hung-Hsiang Lai, Sze-Ya Ting, Pai-Jui Yeh

“…The independent predicting factors for poor outcomes include low hemoglobin and elevated AST levels.…”
Get full text

Effects of Placenta-Derived Mesenchymal Stem Cells on the Particulate Matter-Induced Damages in Human Middle Ear Epithelial Cells by So Young Kim, Seung Ha Oh, Jun Ho Lee, Myung-Whan Suh, Moo Kyun Park

“…The mRNA expression levels of PGE2, TGFβ, and VEGF were elevated in cocultured PL-MSCs compared to those of control PL-MSCs. …”
Get full text

Neutrophil extracellular traps are associated with airways inflammation and increased severity of lung disease in cystic fibrosis by Sheonagh M. Law, Gareth Hardisty, Jonathan L. Gillan, Nicola J. Robinson, Donald J. Davidson, Moira K.B. Whyte, Ian Dransfield, Robert D. Gray

“…Several inflammatory mediators were elevated in CF sputum, as was cell-free DNA. This was highly correlated with sputum calprotectin, a known NET-associated protein. …”
Get full text

Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions by Yu Du, Yufei Song, Xiaojie Zhang, Yan Luo, Wenying Zou, Jiawei Zhang, Jianliang Fu

“…After four weeks of BCAS, wild-type mice showed significant working memory deficits, WMLs, activation of microglia and astrocytes, decrease in the number of oligodendrocytes, downregulation of myelin basic protein expression, and increase in the expression of TNF-α and IL-1β; however, four weeks of BCAS failed to induce significant changes in the LepR-deficient db/db mice but elevated the production of anti-inflammatory cytokines and activated the M2 microglia. …”
Get full text

Dynamic compressive characteristics of a green sandstone under coupled hydraulic-mechanical loading: Experiments and theoretical modeling by Bangbiao Wu, Geli Zhao, Ying Xu, Kaiwen Xia

“…Specifically, the dynamic compressive strength of GS exhibits an increase with higher loading rates and greater confining pressures, while it decreases with elevated pore pressure. Moreover, the classical Ashby-Sammis micromechanical model was augmented to account for dynamic loading and pore pressure considerations. …”
Get full text

Quantitative profiling of the vaginal microbiota improves resolution of the microbiota-immune axis by Eric Armstrong, Rachel Liu, James Pollock, Sanja Huibner, Suji Udayakumar, Erastus Irungu, Pauline Ngurukiri, Peter Muthoga, Wendy Adhiambo, Sergey Yegorov, Joshua Kimani, Tara Beattie, Bryan Coburn, Rupert Kaul

“…Results We analyzed cervicovaginal secretions from 196 female sex workers in Kenya and found that bacterial load was elevated among women with diverse, bacterial vaginosis (BV)-type microbiota and lower among women with Lactobacillus predominance. …”
Get full text

Protective role of vitamin D receptor against mitochondrial calcium overload from PM2.5-Induced injury in renal tubular cells by Mengqiu Lu, Zishun Zhan, Dan Li, Hengbing Chen, Aimei Li, Jing Hu, Zhijun Huang, Bin Yi

“…Results: PM2.5 exposure caused significant mitochondrial damage in renal tubular cells, including mitochondrial calcium overload, increased oxidative stress, reduced membrane potential, and diminished ATP production. Elevated MCU expressions were a key contributor to these disruptions. …”
Get full text

The association between short-term apparent temperature exposure and human coagulation: A time-series study from Beijing, 2014–2023 by Yi Zhang, Tiancheng Wang, Jiaqi Shi, Ying Ma, Nairui Yu, Xinyan Zhou, Pai Zheng, Zhangjian Chen, Guang Jia

“…The findings support that both cold and heat can augment blood coagulability through distinct stages of the coagulation cascade, thereby leading to an elevated risk of thromboembolic diseases.…”
Get full text

Mycotoxicological Assessment of Broiler Compound Feed: A Multi-Year Analysis of Five Mycotoxins in a Romanian Feed Mill by Dragoș Mihai Lăpușneanu, Silvia-Ioana Petrescu, Cristina-Gabriela Radu-Rusu, Mădălina Matei, Ioan Mircea Pop

“…ZEN was consistently elevated at all feeding stages, being detected in 86.5–97.4% of the samples, with maximum levels of 89.4 µg/kg. …”
Get full text

Space Weather Forecasts of Ground Level Space Weather in the UK: Evaluating Performance and Limitations by A. W. Smith, I. J. Rae, C. Forsyth, J. C. Coxon, M.‐T. Walach, C. J. Lao, D. S. Bloomfield, S. A. Reddy, M. K. Coughlan, A. Keesee, S. Bentley

“…Correspondingly, the performance is high when the solar wind conditions are elevated (i.e., high velocity, large total magnetic field strength, and the interplanetary magnetic field oriented southward), and at a minimum when the north‐south component of the magnetic field is highly variable or around zero. …”
Get full text

Association of Myasthenia Gravis With Autoimmune Thyroid Disease: A Bidirectional Mendelian Randomization Study by Yao Wang, Ke Wang, Jing Lu, Peng Xu, Dongmei Zhang, Xinzhi Chen, Jian Wang

“…Genetic predisposition to MG was linked to an increased likelihood of developing Hashimoto's thyroiditis (OR = 1.242(1.073–1.437, P = 0.0036)), and early‐onset MG also exhibited an association with an elevated risk of HT (OR = 1.157(1.073‐1.246), P = 1.269×10−4). …”
Get full text

Clinicopathological relationship between PM2.5 exposure and acute exacerbations of chronic obstructive pulmonary disease by Anfeng Cui, Yingying Shao, Yang Wang, Haodong Wang, Jiayi Song, Caiji Liu, Ningning Shen, Zhiqing Yang, Wangliang Zhang, Tiane Luo, Chen Wang

“…Inflammatory markers (leukocyte and neutrophil counts, eosinophil percentages, C-reactive protein), D-dimer levels, PaCO2, and pulmonary fibrosis indicators showed positive correlations with PM2.5 levels, whereas Pulmonary Function measures (FEV1/ FVC, FEV1 %) and PaO2 showed inverse correlations. Conclusion: Elevated PM2.5 exposure significantly increases the risk of AECOPD, linked to heightened inflammation, pulmonary fibrosis, and diminished pulmonary function, and the majority of these patients are over 60 years old or are smokers. …”
Get full text

Triglyceride glucose-waist circumference as a useful predictor for diabetes mellitus: a secondary retrospective analysis utilizing a Japanese cohort study by Yawei Li, Linlin Shan, Qiong Wen, Changchun Cao, Meiling Huang, Chunxia Zhang, Xiaoping Li, Kun Wang, Tianlun Zhou, Fubing Zha, Yulong Wang

“…Conclusion High levels of TyG-WC are autonomously linked to a heightened risk of diabetes in the Japanese demographic, indicating its potential as a dependable predictive indicator for diabetes mellitus in individuals at elevated risk.…”
Get full text

A High-resolution Spectroscopic Survey of Directly Imaged Companion Hosts. I. Determination of Diagnostic Stellar Abundances for Planet Formation and Composition by Aneesh Baburaj, Quinn M. Konopacky, Christopher A. Theissen, Sarah Peacock, Lori Huseby, Benjamin J. Fulton, Roman Gerasimov, Travis S. Barman, Kielan K. W. Hoch

“…Finally, we find no evidence of highly elevated metallicities or abundances for any of our targets, suggesting that a super metal-rich environment is not a prerequisite for large, widely separated gas planet formation. …”
Get full text

METTL3-dependent DLG2 inhibits the malignant progression of cervical cancer by inactivating the Hippo/YAP signaling by Mei Pu, Xia Xiao, Shasha Lv, Daqing Ran, Qian Huang, Mingming Zhou, Qirong Lei, Lingshuang Kong, Qing Zhang

“…Results DLG2 was underexpressed in cervical cancer tissues and cells. Elevating DLG2 levels significantly suppressed cervical cancer cell proliferation, migration, and invasion, while promoting apoptosis. …”
Get full text