Profiling Serum Cytokines and Anticytokine Antibodies in Psoriasis Patients by Dan Hong, Xiuting Liu, Xiaonan Qiu, Siyao Lu, Yanyun Jiang, Guozhen Tan, Zhenrui Shi, Liangchun Wang

“…Cytokines like IL-17A have been consistently found to be elevated in psoriatic lesional skin, and therapeutic antibodies to IL-17 have demonstrated efficacy in treating psoriatic skin and joint disease. …”
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Long-Term Trends and Ecological Risks of Heavy Metal Accumulation in Cultivated Land of Songnen Plain, China by Zonglai Liu, Jinying Li, Yanan Chen, Fengjun Zhang, Wei Feng

“…Meanwhile, the single-factor pollution index indicates elevated pollution levels of Zn, Cu, and Cd. Potential ecological risk assessment reveals that certain areas within Changchun and Baicheng cities exhibit higher ecological risks. …”
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C1q Levels: A Reliable Biomarker for Differentiating Active and Latent Tuberculosis Infection by Sepideh Darougar, Afshin Moniri, Parvaneh Baghaei, Esmaeil Mortaz, Makan Sadr, Arad Moniri, Majid Marjani, Payam Tabarsi

“…The active TB group exhibited significantly elevated C1q levels (10.21 μg/ml) compared to the latent TB group (6.03 μg/ml, P < 0.001). …”
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Melatonin attenuates MPP+-induced autophagy via heat shock protein in the Parkinson’s disease mouse model by Yinli Guo, Chengbo Liu

“…The expression levels of HSP70 and CDK5 were significantly elevated, while the expression levels of LC3 II /LC3I and p62 protein were significantly decreased. …”
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The influence of light and heavy training weeks on the cortisol and testosterone awakening responses of elite male judokas: is skeletal muscle damage a mediating factor? by Blair T. Crewther, Benjamin G. Serpell, Christian J. Cook, Zbigniew Obmiński

“…The post-awakening decline in plasma testosterone (TAR Δb30 , TAR AUCb30 , TAR AUCb60 ) was found to be significantly less pronounced, whilst CK level was elevated, after heavy than light training with effect-size differences of 0.95–1.04 and 4.70, respectively. …”
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Age-related lung changes linked to altered lysosomal protease profile, histology, and ultrastructure. by Mohammed Aufy, Mahmoud Abd-Elkareem, Medina Mustafic, Mostafa A Abdel-Maksoud, Ali Hakamy, Veronika Baresova, Akram A Alfuraydi, Mahmoud Ashry, Jana Lubec, Ayman S Amer, Christian R Studenik, Ahmed M Hussein, Mohamed H Kotob

“…Zymography analysis revealed elevated MMP activity in the old lung tissues compared to the young ones. …”
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Networking Salt Inducible Kinase 1 Regulatory Perturbations on Type 2 Diabetes- Breast Cancer Co-Morbidity Associated Molecular Bridge by Durrani I.A., John P., Bhatti A.

“…Type 2 diabetes mellitus (T2DM) is associated with a 16% elevated risk of breast cancer (BC). However, the underlying molecular mechanisms are yet to be fully understood. …”
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Association of oxidative balance score with all-cause and cardiovascular mortality in overweight and obese by Shuxin Ying, Hongyan Ding, Yanjin Chen, Su Zheng

“…Mediation analysis indicates that white blood cell count (WBC) and gamma-glutamyl transferase (GGT) serve as significant mediators in the association between OBS and mortality risk.ConclusionElevated levels of OBS were strongly linked to reduced potential for both cardiovascular and all-cause mortality among individuals who are overweight or obese.…”
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The causal impact of smoking behavior on osteoarthritis: a Mendelian randomization analysis by Qiang Xiao, Susu Dong, Yafen Tan, Xuan Zhang, Lu Yao, Qiuping Li, Tianli Wang

“…Similarly, lifetime smoking elevated the risk of knee OA by 101%, hip OA by 55%, and knee/hip OA by 84% (all p &lt; 0.001). …”
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When to Consider a Diagnosis of Maturity-Onset Diabetes of the Young: Precise Diagnosis Leads to Better Management and Quality of Life for the Patients by Yujia Gao, Kalyan Mansukhbhai Shekhda, Sarah N. Ali

“…A 33-year-old South Asian lady was referred to a diabetes clinic for suspected T2DM due to strong family history of T2DM, ethnicity, and persistently elevated fasting blood glucose levels. Her genetic testing confirmed GCK-MODY (Glucokinae-maturity-onset diabetes of the young). …”
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Evaluation of Peripapillary Nerve Fiber Layer after Dexamethasone Implantation (Ozurdex) in Branch Retinal Vein Occlusions by Muhammed Nurullah Bulut, Yusuf Özertürk, Ümit Çallı, Güzide Akçay, Ulviye Kıvrak, Kezban Bulut

“…Ozurdex implant improved the BCVA and reduced the CMT in the eyes with RVO related ME. However, IOP elevations occurred within the first month after the injection and the average and inferior quadrant RNFL thinning was found six months after the injection. …”
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Incidence of HBV Reactivation in Psoriasis Patients Undergoing Cytokine Inhibitor Therapy: A Single-Center Study and Systematic Review with a Meta-Analysis by Meng Hsuan Kuo, Ping-Hung Ko, Sz-Tsan Wang, Chih-Wei Tseng

“…Background: Psoriasis patients who are seropositive for hepatitis B surface antigen (HBsAg) or hepatitis B core antibody (HBcAb) face an elevated risk of hepatitis B virus reactivation (HBVr) when treated with cytokine inhibitors. …”
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Association between red blood cell distribution width-to-albumin ratio at admission and all-cause mortality in patients with acute pancreatitis based on the MIMIC-III database. by Qingsong Wu, Lianyi Liao, Qingjun Deng

“…Multivariate Cox regression analysis confirmed that an elevated RAR was independently associated with increased mortality at 28 day (HR, 2.72; 95% CI, 1.64-4.52; p < 0.001).…”
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The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity by Lynda Bourebaba, Anna Serwotka-Suszczak, Nabila Bourebaba, Magdalena Zyzak, Krzysztof Marycz

“…Moreover, MSI-1436 enhanced the anti-inflammatory profile of livers by elevating the expression of IL-10 and IL-4 and activating CD4+CD25+Foxp3+ regulatory T cells in treated PBMC. …”
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Waist-to-Height Ratio (WHtR) in Predicting Coronary Artery Disease Compared to Body Mass Index and Waist Circumference in a Single Center from Saudi Arabia by Mostafa Q. Alshamiri, Faisal Mohd A Habbab, Saad Saeed AL-Qahtani, Khalil Abdullah Alghalayini, Omar Mohammed Al-Qattan, Fayez El-shaer

“…WHtR is superior to BMI and WC for determining the elevated risk of diabetes, hypertension, dyslipidemia, and CAD in a single university institute. …”
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Development and Evaluation of Polymethacrylate-Based Ophthalmic Nanofiber Inserts Containing Dual Drug-Loaded Dorzolamide and Timolol: In Vivo Study in Rabbit’s Eye by Ahmad Karami, Shahla Mirzaeei, Leila Rezaei, Ali Nokhodchi

“…This condition encompasses a variety of chronic, advancing ocular disorders typically associated with elevated intraocular pressure (IOP). <b>Methods:</b> The insert was made of Eudragite RL100 (EUD) polymer, a biocompatible material with high bioavailability, using the electrospinning method. …”
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Climate adaptation and resilience of biofiltration as a low-cost technological solution for water treatment – A critical review by Adedamola Adesomi Ali, Oliver Terna Iorhemen, Ronald W. Thring

“…Following wildfires, the erosion of ashes and unburnt carbon into surface water bodies results in higher turbidity and total suspended solids in surface water, along with elevated concentrations of dissolved organic matter. …”
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Scrutinizing the untapped potential of emerging ABSe3 (A = Ca, Ba; B = Zr, Hf) chalcogenide perovskites solar cells by Dhineshkumar Srinivasan, Aruna-Devi Rasu Chettiar, Eupsy Navis Vincent Mercy, Latha Marasamy

“…The maximum PCE of over 30% was attained for both CaZrSe3and BaZrSe3 solar cells, attributed to their narrow bandgap, enhanced light absorption (53.60%), high JSC (29 mA/cm2), and elevated generation rate of 1.19 × 1022 cm−2s−1. Thus, these significant outcomes highlight the potential of these absorbers for fabricating high-efficiency CP solar cells.…”
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Clinical Factors of Blood Transfusion-Related Acute Lung Injury and Changes in Levels of Treg-Related Cytokines by Lifang Sun, Yu Liu

“…CD4 + CD25 + Treg was positively correlated with levels of IL-10 and TGF-β (P<0.05). Conclusion. Elevated HLA antibody II and CD4 + CD25 + Treg are the main clinical risk factors for TRALI, and CD4 + CD25 + Treg may be involved in immunosuppression by increasing the expression levels of IL-10 and TGF-β. …”
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Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model by Ningxun Cui, Mingling Cui, Jie Li, Xueping Zhu, Xiaoli Zhu

“…Besides, the value of biochemical parameters (TBIL, DBIL, ALT, and AST) was also elevated in the SO group compared with the NG group. …”
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