PD‐1+CD8+ T Cell‐Mediated Hepatocyte Pyroptosis Promotes Progression of Murine Autoimmune Liver Disease by Jie Long, Si‐Yu Yang, Zhen‐Hua Bian, Hao‐Xian Zhu, Min Ma, Xiao‐Qing Wang, Liang Li, Weici Zhang, Ying Han, M. Eric Gershwin, Zhe‐Xiong Lian, Zhi‐Bin Zhao

“…In vitro experiments reveal that PD‐1+CD8+ T cells can induce the pyroptosis of hepatocytes through elevated production of granzyme B and perforin‐1. These results provide a novel explanation for the cytotoxic activity of pathogenic liver PD‐1+CD8+ T cells in autoimmune liver diseases and offer potential therapeutic targets.…”
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Tumor Anti-Initiation and Anti-Progression Properties of Sulphated-Extract of Colocasia esculenta by Amira M. Gamal-Eldeen, Hassan Amer ‎, Cinderella A. ‎ Fahmy, Haytham ‎ Dahlawi, Basem H ‎ Elesawy, Nahla L. ‎ Faizo, Bassem M. ‎ Raafat

“…It induced lymphocyte growth and modulated the macrophage functions into an anti-inflammatory profile, via elevating macrophage proliferation and its binding affinity of fluorescein isothiocyanate-lipopolysaccharide (FITC-LPS) and inhibiting nitric oxide and tumor necrosis factor-α generation. …”
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Nonoperative management of colon and mesocolon injuries caused by blunt trauma: three case reports by Naa Lee, Euisung Jeong, Hyunseok Jang, Yunchul Park, Younggoun Jo, Jungchul Kim

“…In the third case, follow-up CT and percutaneous drainage were performed in considering the persistent left abdominal discomfort, fever, and elevated inflammatory markers of the patient. After that, outpatient CT showed improvement of the hematoma. …”
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Measurement report: A comparative analysis of an intensive incursion of fluorescing African dust particles over Puerto Rico and another over Spain by B. Sarangi, D. Baumgardner, A. I. Calvo, B. Bolaños-Rosero, R. Fraile, A. Rodríguez-Fernández, D. Fernández-González, C. Blanco-Alegre, C. Gonçalves, E. D. Vicente, O. L. Mayol-Bracero, O. L. Mayol-Bracero

“…The León event occurred in the late winter and spring of 2022, when widespread, elevated layers of dust inundated the Iberian Peninsula. …”
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A Hyperlipidic Diet Combined with Short-Term Ovariectomy Increases Adiposity and Hyperleptinemia and Decreases Cytokine Content in Mesenteric Adipose Tissue by Nelson Inacio Pinto Neto, Maria Elizabeth Sousa Rodrigues, Ana Claudia Losinskas Hachul, Mayara Franzoi Moreno, Valter Tadeu Boldarine, Eliane Beraldi Ribeiro, Lila Missae Oyama, Claudia Maria Oller do Nascimento

“…A hyperlipidic diet for 8 weeks combined with short-term ovariectomy decreases the cytokine content of MES adipose tissues but increases BW, enhancing FE and elevating serum leptin levels. These suggest that the absence of estrogens promotes metabolic changes that may contribute to installation of a proinflammatory process induced by a hyperlipidic diet.…”
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Comprehensive review of mapping climate change impacts on tea cultivation: bibliometric and content analysis of trends, influences, adaptation strategies, and future directions by Altyeb Ali Abaker Omer, Altyeb Ali Abaker Omer, Chun-Hua Zhang, Chun-Hua Zhang, Jie Liu, Jie Liu, Zhi-guo Shan, Zhi-guo Shan

“…Climate change has a profound impact on tea cultivation, posing significant challenges to yield, quality, and sustainability due to stressors such as drought, temperature fluctuations, and elevated CO₂ levels. This study aims to address these challenges by identifying and synthesizing key themes, influential contributions, and effective adaptation strategies for mitigating the impacts of climate change on tea production. …”
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A Reduction in Selenoprotein S Amplifies the Inflammatory Profile of Fast-Twitch Skeletal Muscle in the mdx Dystrophic Mouse by Craig Robert Wright, Giselle Larissa Allsopp, Alex Bernard Addinsall, Natasha Lee McRae, Sofianos Andrikopoulos, Nicole Stupka

“…Gene polymorphisms in Selenoprotein S (Seps1) are associated with elevated proinflammatory cytokines, and in vitro SEPS1 is protective against inflammatory stress. …”
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Development and Characterization of Mikania, Kapok, Wool, Sugarcane, and Pineapple Fiber Reinforced Polyester Composite by Rafid Anan, Hasan Al Mahmud, Tabriz Ahnaf Khan, Md Sakib Ul Alam Sakib, Md Shahadhat Hossain

“…The kapok provided an impact toughness of 1.2 N m, which was somewhat elevated. This research offers a precious understanding of using natural fibers as strengthening additives in polyester composites, demonstrating their flexible perspective for many uses. …”
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Solid-Pseudopapillary Tumor of the Pancreas: A Single Center Experience by Valentina Beltrame, Gioia Pozza, Enrico Dalla Bona, Alberto Fantin, Michele Valmasoni, Cosimo Sperti

“…Serum CA 19-9 was slightly elevated in one case. Preoperative diagnosis was neuroendocrine tumor (n=2), mucinous tumor (n=2), and SPT (n=14). …”
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Understanding and Modeling the Dynamics of Storm‐Time Atmospheric Neutral Density Using Random Forests by K. Murphy, A. J. Halford, V. Liu, J. Klenzing, J. Smith, K. Garcia‐Sage, J. Pettit, I. J. Rae

“…Abstract Atmospheric neutral density is a crucial component to accurately predict and track the motion of satellites. During periods of elevated solar and geomagnetic activity atmospheric neutral density becomes highly variable and dynamic. …”
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Food consumption and adherence to dietary guidelines among Jordanian children and adolescents [version 4; peer review: 1 approved, 3 approved with reservations] by Islam K. Al-Shami, Buthaina Alkhatib, Huda Al Hourani, Ayoub Al-Jawaldeh

“…The prevalence of overweight/obesity was elevated compared to international norms.…”
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Association of Haemostatic and Inflammatory Biomarkers with Nephropathy in Type 1 Diabetes Mellitus by Caroline Pereira Domingueti, Rodrigo Bastos Fóscolo, Janice Sepúlveda Reis, Fernanda Magalhães Freire Campos, Luci Maria S. Dusse, Maria das Graças Carvalho, Karina Braga Gomes, Ana Paula Fernandes

“…VWF, ADAMTS13 antigen, and D-Dimer plasma levels were determined by enzyme-linked immunosorbent assay and ADAMTS13 activity was assessed by fluorescence resonance energy transfer assay. Elevated levels of INF-γ, VWF, ADAMTS13 antigen, D-Dimer, and reduced ADAMTS13 activity/antigen ratio were observed in patients with nephropathy as compared to those without nephropathy (P=0.001, P<0.001, P<0.001, P<0.001, and P<0.001, resp.). …”
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Retrotrans-genomics identifies aberrant THE1B endogenous retrovirus fusion transcripts in the pathogenesis of sarcoidosis by Shunsuke Funaguma, Aritoshi Iida, Yoshihiko Saito, Jantima Tanboon, Francia Victoria De Los Reyes, Kyuto Sonehara, Yu-ichi Goto, Yukinori Okada, Shinichiro Hayashi, Ichizo Nishino

“…Here we report identification of 19 THE1B fusion transcripts through short- and long-read RNA-seq analysis, 15 of which are previously unmapped, showing elevated expression in 16 individuals with sarcoid myopathy (SM), as compared to 400 controls with various other muscle diseases. …”
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Effect of interface morphology on tensile response of Ti6Al4V alloy fabricated by laser hybrid additive manufacturing: Experiments &amp; simulations by Wei Fan, Guang Hu, Yuguang Chen, Yue Du, Yijie Peng, Yongxia Wang, Yunlong Li, Hua Tan, Fengying Zhang, Xin Lin

“…However, curved interfaces exacerbate stress concentration in the central wrought substrate, elevating stress peaks at the distal end of the interface. …”
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Cardiac secreted HSP90α exacerbates pressure overload myocardial hypertrophy and heart failure by Le Pan, Chenxing Huang, Xuejuan Jin, Jian Wu, Kejia Jin, Jingyi Lin, Ying Wang, Jianxuan Li, Chao Yin, Xiang Wang, Lei Zhang, Guoping Zhang, Hangming Dong, Junli Guo, Issei Komuro, Yuxiang Dai, Yunzeng Zou, Hui Gong

“…Compared to controls, elevated serum HSP90α levels were observed in patients with hypertension or AS, and the levels positively correlated with LVH. …”
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Prevalence of diabetes and prediabetes in South Asian countries: a systematic review and meta-analysis by Masum Ali, Md Mahbub Alam, M. A. Rifat, Sonjida Mesket Simi, Sneha Sarwar, Md Ruhul Amin, Sanjib Saha

“…Conclusion The analyses revealed that the prevalence of diabetes and prediabetes in South Asia throughout the study period is significantly elevated. This necessitates the establishment of comprehensive guidelines for South Asians to mitigate the escalating prevalence of diabetes and prediabetes.…”
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IGF2BP3 curbed by miR-15c-3p restores disrupted lipid storage and progesterone secretion in chicken granulosa cells under oxidative stress through AKT-Raf1-ERK1/2 signaling pathway by Zhongzhen Lin, Yanrong Gong, Chunlin Yu, Chaowu Yang, Lingqian Yin, Donghao Zhang, Yuan Tang, Feng Xu, Ye Wang, Yiping Liu

“…Small RNA sequencing revealed that miR-15c-3p expression was elevated by oxidative stress induction and attenuated by antioxidant curcumin. …”
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Effects and Potential Mechanisms of Pioglitazone on Lipid Metabolism in Obese Diabetic KKAy Mice by Jun Peng, Yi Huan, Qian Jiang, Su-juan Sun, Chun-ming Jia, Zhu-fang Shen

“…Pioglitazone treatment resulted in deteriorated microvesicular steatosis and elevated hepatic triglyceride levels, though plasma triglyceride and free fatty acid levels were reduced by the treatment, compared to nontreated KKAy mice. …”
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Temperature-dependent performance and constitutive modeling of additively manufactured Ti600 alloy by Tianhua Wen, Rui Fu, Sihang Xiao, Lei Zhang, Bo Song, Hongshuai Lei

“…Compared to the conventional Johnson-Cook constitutive model, the BTD model demonstrates superior accuracy in predicting stress-strain behavior at elevated temperatures. This study addresses the gap in knowledge regarding the high-temperature thermal and mechanical behavior of SLM-fabricated Ti600, offering valuable insights for its broader industrial application.…”
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Diagnosis and clinical significance of prostate calcification using computed tomography by Seong Cheol Kim, Tae Young Lee, Woocheol Kang, Hoyoung Bae, Ji Hyung Yoon, Sungchan Park, Kyung Hyun Moon, Sang Hyeon Cheon, Taekmin Kwon

“…Total IPSS scores were significantly elevated in the calcification group, particularly in those with calcifications of HU ≥ 100. …”
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