Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation by Shuxiao Chen, Xiaotian Liu, Xincheng Zhou, Weixiao Lin, Minting Liu, Haoran Ma, Keli Zhong, Qiming Ma, Chengjian Qin, Chengjian Qin

“…Mechanistically, phospho-AMPK expression was elevated in AAA groups, and ATL-I administration suppressed its expression to improve the pathological damage of aorta.ConclusionsATL-I meliorated vascular inflammation by targeting AMPK signaling, ultimately inhibiting AAA formation, which provided an alternative agent for AAA treatment.…”
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Defect engineering and alloying strategies for tailoring thermoelectric behavior in GeTe and its alloys by Qiyong Chen, Cheng Yang, Tong Xing, Jinyang Xi, Wenqing Zhang, Jiong Yang, Lili Xi

“…However, GeTe is prone to producing Ge vacancies, leading to high p-type carrier concentration, which results in elevated electronic thermal conductivity and a low Seebeck coefficient. …”
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The Appearance of Antiphage Antibodies in Sera of Patients Treated with Phages by Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Maciej Żaczek, Ryszard Międzybrodzki, Andrzej Górski

“…Patients with bone infections treated locally with the <i>S. aureus</i> phage Staph_1N and patients with upper respiratory tract infections administered locally and orally with the <i>S. aureus</i> phage Staph_A5L had elevated levels of antiphage antibodies in sera during PT. …”
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Hyperleptinemia, Adiposity, and Risk of Metabolic Syndrome in Older Adults by Suruchi Mishra, Tamara B. Harris, Trisha Hue, Iva Miljkovic, Suzanne Satterfield, Nathalie de Rekeneire, Mira Mehta, Nadine R. Sahyoun

“…Conclusion. Among older women, elevated concentrations of leptin may increase the risk of metabolic syndrome independent of adiposity and cytokines.…”
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Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma by Yuli Jian, Kangkang Yang, Jinjing Li, Ling Tang, Guang Zeng, Xiaoxin Sun, Xiao Yu, Abdullah Al-danakh, Qiwei Chen, Deyong Yang, Shujing Wang

“…In the study, through systematic bioinformatics analysis and experimental verification, we demonstrated that ST3Gal5 expression was elevated in tumor tissues of KIRC patients, correlating with poor prognosis, and ST3Gal1 was downregulated and associated with a better prognosis. …”
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Impact of Biomass Burning on Air Quality in Temuco City, Chile by Felipe Reyes, Sofía Ahumada, Francisca Rojas, Pedro Oyola, Yeanice Vásquez, Claudio Aguilera, Andres Henriquez, Ernesto Gramsch, Choong-Min Kang, Sanna Saarikoski, Kimmo Teinilä, Minna Aurela, Hilkka Timonen

“…In the wintertime, atmospheric levels of biomass burning tracers, such as levoglucosan, potassium and chloride, were elevated and their diurnal profiles showed a significant concentration increase in the evening. …”
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State updating of the Xin'anjiang model: joint assimilating streamflow and multi-source soil moisture data via the asynchronous ensemble Kalman filter with enhanced error models by J. Gong, J. Gong, X. Liu, C. Yao, C. Yao, Z. Li, A. H. Weerts, A. H. Weerts, Q. Li, S. Bastola, Y. Huang, J. Xu

“…Tests involving both synthetic and real-world cases demonstrates that assimilation of these two types of observations simultaneously substantially reduces the accumulation of past errors in the initial conditions at the start of the forecast, thereby aiding in elevating the accuracy of flood forecasting. Moreover, the AEnKF with the enhanced error model consistently yields greater forecasting accuracy across various lead times compared to the standard EnKF.…”
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PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice by Ying Sun, Zhanjun Jia, Gang Liu, Li Zhou, Mi Liu, Baoxue Yang, Tianxin Yang

“…Strikingly, urinary PGE2 was remarkably elevated in db/db mice paralleled with the increased protein expressions of COX-2 and mPGES-1. …”
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Hydrogen Sulfide Increases Nitric Oxide Production and Subsequent S-Nitrosylation in Endothelial Cells by Ping-Ho Chen, Yaw-Syan Fu, Yun-Ming Wang, Kun-Han Yang, Danny Ling Wang, Bin Huang

“…In this study, a treatment with NaHS profoundly increased the expression and the activity of endothelial nitric oxide synthase. Elevated gaseous NO levels were observed by a novel and specific fluorescent probe, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester (FA-OMe), and quantified by flow cytometry. …”
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The association of visceral fat metabolism score with hyperuricemia—evidence from NHANES 1999–2018 by Lin Xie, Huali Qu, Dandan Lai, Juan Li, Xushan Chen, Jiajia Xie

“…Propensity score matching (PSM), multivariate logistic regression analysis, subgroup analysis, interaction test, and restricted cubic spline (RCS) analysis were implemented to identify the correlation between METS-VF and HUA.ResultsIn the fully adjusted model, the results of the multiple logistic regression analysis indicated that METS-VF was related to an elevated prevalence of HUA [before PSM: odds ratio (OR) = 3.51 (2.88, 4.27), p &lt; 0.001; after PSM: OR = 2.90 (2.36, 3.58), p &lt; 0.001]. …”
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Dias-Logan syndrome with a p.Leu360Profs*212 heterozygous pathogenic variant of in a Chinese patient: A case report by Yizhuo Shu, Xiaoling Chen, Zhuoqun Wei, Chunyue Chen

“…All his blood parameters were normal except for an elevated HbF level, which was 19.9% of total hemoglobin. …”
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Epstein-Barr Virus-Induced Gene 3 (EBI3) Blocking Leads to Induce Antitumor Cytotoxic T Lymphocyte Response and Suppress Tumor Growth in Colorectal Cancer by Bidirectional Reciproc... by Yanfang Liang, Qianqian Chen, Wenjing Du, Can Chen, Feifei Li, Jingying Yang, Jianyu Peng, Dongping Kang, Bihua Lin, Xingxing Chai, Keyuan Zhou, Jincheng Zeng

“…In this study, firstly we assessed EBI3, IL-27p28, IL-12p35, gp130, and p-STAT3 expression with clinicopathological parameters of colorectal cancer (CRC) tissues; then we evaluated the antitumor T cell responses and tumor growth with a EBI3 blocking peptide. We found that elevated EBI3 may be associated with IL-12p35, gp130, and p-STAT3 to promote CRC progression. …”
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Domestication of medicinal plants (Lonicera japonica Thunb.) in China: comparison of morphological, resistance and biochemical traits between wild and cultivated populations by Congzhe Hou, Luyao Huang, Zhuangzhuang Li, Nan Sun, Sheng Yang, Jia Li, Zhenhua Liu

“…Additionally, the cultivated specimen demonstrated significantly elevated levels of chlorogenic acid as a biochemical constituent. …”
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Microstructural transition from ZrO₂ to Zr–Al intermetallics and property evolution in AA5051 composites by G. Anbuchezhiyan, G. Ananth, Vignesh M, K. Logesh, Nabisab Mujawar Mubarak, Elango Natarajan

“…Incorporating ZrO2 addresses these challenges by refining the grain structure, generating thermally stable secondary phases, and minimising diffusion processes which influence mechanical properties at elevated temperatures. In the current scenario, ZrO2-reinforced AA5051 alloy composites were synthesised by the squeeze casting process, and its microstructure and mechanical characteristics were analysed for high-performance components. …”
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Autophagy-related long non-coding RNA MIR210HG plays a therapeutic role in hepatocellular carcinoma by Chaoqun Zhang, Dianxing Sun, Huifang Zhou, Chao Liu, Jie Ruan, Jiwen Kang, Ying Xie

“…Functional assays, including CCK-8, Transwell, flow cytometry, and western blot, were performed to evaluate the effects of lncRNA MIR210HG on cell proliferation, invasion, apoptosis, and autophagy in hepatocellular carcinoma. Results Elevated lncRNA MIR210HG expression correlated with poor overall survival in hepatocellular carcinoma patients. …”
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Impact of ABO gene polymorphism and von Willebrand factor on genetic susceptibility to acute lymphoblastic leukemia in Egyptian pediatric patients by Elsayed I. Salim, Ahmed N. Shaaban, Amal K. Seleem, Zeinab I. Attia

“…Conclusion The ABO C allele and O, A, and B blood groups are associated with increased pediatric ALL susceptibility in Egyptian patients, potentially through elevated VWF levels. These findings highlight ABO gene polymorphisms and blood groups as possible risk factors for ALL development.…”
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Effects of Luteolin Treatment on Postharvest Quality and Antioxidant Capacity of Nanfeng Tangerines by Wenjuan Dong, Xiaohan Wang, Miaolian Xiang, Jinyin Chen, Jiaoke Zeng, Ming Chen

“…Furthermore, luteolin treatment inhibited malondialdehyde (MDA) and H₂O₂ accumulation by enhancing the content of total phenols and flavonoids content, augmenting antioxidant enzyme activities (peroxidase (POD), catalase (CAT), and superoxide dismutase (SOD)), and elevating the overall antioxidant capacity measured through the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging rate. …”
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Apolipoprotein C-I Levels Are Associated with the Urinary Protein/Urinary Creatinine Ratio in Pediatric Idiopathic Steroid-Sensitive Nephrotic Syndrome: A Case Control Study by Jun Odaka, Takahiro Kanai, Takane Ito, Takashi Saito, Jun Aoyagi, Hiroyuki Betsui, Takanori Yamagata

“…Four ion peaks with a mass-to-charge ratio (m/z) of 6,444, 6,626, 8,695, and 8,915 were significantly elevated during ISSNS Phase A1 compared to Phase A2, Phase A3, and Group C. …”
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Relevance of Plasma Obestatin and Early Arteriosclerosis in Patients with Type 2 Diabetes Mellitus by Peng-ying Gu, Dong-mei Kang, Wei-dong Wang, Yan Chen, Zhi-hong Zhao, Hui Zheng, Shan-dong Ye

“…Therefore, we deduced that the low level of plasma obestatin might be related to early arteriosclerosis in patients with T2DM via increasing IMT level, and elevated plasma obestatin levels might protect T2DM patients against carotid atherosclerosis to some extent.…”
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Estimation of D-dimer, C-reactive protein and ferritin in Covid-19 survivors in a North Indian Hospital, Lucknow, India. by Chetna Singla, Dhananjay Tiwari, Himali Jha, Mohammad Mustufa Khan, Sadaf Parveen, Roshan Alam

“…The mean of D-dimer was found to be elevated in COVID-19 survivors as compared to controls (p<0.0001). …”
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