Bacteriophage LDT325 enhances Pseudomonas syringae tolerance by improving antioxidant defense in tea plant [Camellia sinensis (L.) O. Kuntze] by Li Liu, Anqi Huang, Hua Zhang, Yubao Li, Lei Wang, Lei Wang

“…The levels of osmotic adjustment compounds, including proline and soluble sugars, were also elevated, suggesting that bacteriophage enhances the osmotic adjustment capacity in tea plants. …”
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Diagnostic Value of Fecal Calprotectin (S100 A8/A9) Test in Children with Chronic Abdominal Pain by Stanisław Pieczarkowski, Kinga Kowalska-Duplaga, Przemko Kwinta, Przemysław Tomasik, Andrzej Wędrychowicz, Krzysztof Fyderek

“…In patients with IBD FCCs were markedly elevated with median value of 1191.5 μg/g. However, in children with inflammatory gastrointestinal disorders other than IBD and in children with IBD mean FCCs were significantly higher compared with the control group. …”
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Implication of Nonalcoholic Fatty Liver Disease, Metabolic Syndrome, and Subclinical Inflammation on Mild Renal Insufficiency by Ga Eun Nam, Soon Young Hwang, Hye Soo Chung, Ju Hee Choi, Hyun Jung Lee, Nam Hoon Kim, Hye Jin Yoo, Ji-A Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi

“…Multivariate logistic regression analysis demonstrated the independent association of NAFLD (P=0.034) and MetS (P=0.018) with mild renal insufficiency, but not elevated hsCRP (P=0.885). Furthermore, NAFLD without the MetS group (odds ratio (95% confidence interval) = 1.56 (1.05–2.34)) or MetS without the NAFLD group (1.82 (1.11–3.00)) was associated with mild renal insufficiency after adjusting for confounding variables. …”
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Towards the Sustainable Removal of Heavy Metals from Wastewater Using <i>Arthrospira platensis</i>: A Laboratory-Scale Approach in the Context of a Green Circular Economy by Lamprini Malletzidou, Eleni Kyratzopoulou, Nikoletta Kyzaki, Evangelos Nerantzis, Nikolaos A. Kazakis

“…In particular, Cu, Cd, Pb, and Zn removal of multi-MT cultures is elevated or relative to the respective removal of the mono-metal-treated (mono-MT) cultures, showing a synergistic or cooperative interaction between the metals, while the removal of Ni of multi-MT cultures decreased compared to Ni of mono-MT cultures, showing an antagonistic interaction to the other metals. …”
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Clinical and Renal Biopsy Findings Predicting Outcome in Renal Thrombotic Microangiopathy: A Large Cohort Study from a Single Institute in China by Xiao-Juan YU, Feng YU, Di Song, Su-Xia Wang, Yan Song, Gang Liu, Ming-Hui Zhao

“…In multivariate analysis, male, elevated serum creatinine, and decreased hemoglobin were independently associated with poor renal outcomes. …”
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Increased Expression of TLR10 in B Cell Subsets Correlates with Disease Activity in Rheumatoid Arthritis by Ying Zhang, Rong Cao, Haijian Ying, Juping Du, Shuaishuai Chen, Na Wang, Bo Shen

“…Compared to that in the HCs, TLR10 was elevated significantly in the CD19+CD27−IgD− and CD19+CD5+ subsets in the RA subjects. …”
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Sugemule-7 alleviates oxidative stress, neuroinflammation, and cell death, promoting synaptic plasticity recovery in mice with postpartum depression by Qiang Fu, Rui Qiu, Jiaquan Liang, Shuai Wu, Dezhi Huang, Yuxiang Qin, Qiaosheng Li, Xiaojie Shi, Xiyue Xiong, Zhongyong Jiang, Yuewen Chen, Yong Cheng

“…Our study demonstrated that varying doses of Sugemule-7 effectively alleviated depressive and anxiety-like behaviors in PPD mice, as assessed through a battery of tests, including the open field test, tail suspension test, sucrose preference test, forced swim test, novelty-suppressed feeding test, and elevated plus maze test. Furthermore, Sugemule-7 significantly improved oxidative stress levels in the serum, prefrontal cortex, and hippocampus of PPD-induced mice while also suppressing inflammatory responses and abnormal neuronal death in these brain regions. …”
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Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension by Justin H. Berger, Yuji Shi, Timothy R. Matsuura, Kirill Batmanov, Xian Chen, Kelly Tam, Mackenzie Marshall, Richard Kue, Jiten Patel, Renee Taing, Russell Callaway, Joanna Griffin, Attila Kovacs, Dinesh Hirenallur-Shanthappa, Russell Miller, Bei B. Zhang, Rachel J. Roth Flach, Daniel P. Kelly

“…HFD-Renin (aka “HFpEF”) mice demonstrated obesity and insulin resistance, moderate left ventricular hypertrophy, preserved systolic function, and diastolic dysfunction indicated by echocardiographic measurements; increased left atrial mass; elevated natriuretic peptides; and exercise intolerance. …”
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Brain health in Norwegian female former top-level football players: a protocol for a longitudinal cohort study by Thor Einar Andersen, Roald Bahr, Emilie Isager Howe, Peter Filipcik, John Bjørneboe, Geir Selbaek, Sara Christina Dahlén, Stian Kirkerud Sandmo, Lena Bache-Mathisen, Einar August Høgestøl, Truls Straume-Næsheim, Lars T Westlye

“…Recent studies have identified an association between playing football at the top level and an elevated risk of cognitive impairment and neurodegenerative disease. …”
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Forecasting the Probability of Large Rates of Change of the Geomagnetic Field in the UK: Timescales, Horizons, and Thresholds by A. W. Smith, C. Forsyth, I. J. Rae, T. M. Garton, T. Bloch, C. M. Jackman, M. Bakrania

“…Large GICs may be induced when the rate of change of the ground magnetic field is significantly elevated. We assess the ability of three different machine learning model architectures to process the time history of the incoming solar wind and provide a probabilistic forecast as to whether the rate of change of the ground magnetic field will exceed specific high thresholds at a location in the UK. …”
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The histone demethylase KDM5C enhances the sensitivity of acute myeloid leukemia cells to lenalidomide by stabilizing cereblon by Lu Zou, Dan Cao, Qing Sun, Wenjun Yu, Bingzong Li, Guoqiang Xu, Liang Zhou

“…Furthermore, our studies revealed that the small-molecule compound MLN4924 could increase CRBN by elevating KDM5C.The combination of MLN4924 and Len can further increase the sensitivity of primary AML cells and AML cell lines to Len. …”
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The factors impacting on Gleason score upgrading in prostate cancer with initial low Gleason scores by Tzu-Heng Huang, Wei-Ming Li, Hung-Lung Ke, Ching-Chia Li, Wen-Jeng Wu, Hsin-Chih Yeh, Yen-Chun Wang, Hsiang-Ying Lee

“…Conclusion: Smaller PV and elevated PSAD are associated with increased risk of GS upgrading, whereas lead-time bias is not. …”
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Prevalence and determinants of ideal cardiovascular health by sex and region—a population-based study in Peru by Víctor Juan Vera-Ponce, Víctor Juan Vera-Ponce, Fiorella E. Zuzunaga-Montoya, Fiorella E. Zuzunaga-Montoya, Luisa Erika Milagros Vásquez-Romero, Joan A. Loayza-Castro, Eder Jesús Orihuela Manrique, Mario J. Valladares-Garrido, Mario J. Valladares-Garrido, Mario J. Valladares-Garrido, Carmen Inés Gutierrez De Carrillo, Carmen Inés Gutierrez De Carrillo

“…The prevalence is trending lower in correlation with rising age and educational attainment levels and for those inhabitants residing at higher elevations. Likewise, statistically significant variations were observable concerning the prevalence of ICVH contingent on the region of residence and marital status, in particular amongst the feminine inhabitants.ConclusionsThese results demonstrate that the frequency of ICVH in the grown-up inhabitants of Peru is comparatively tiny. …”
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Niraparib restricts intraperitoneal metastases of ovarian cancer by eliciting CD36-dependent ferroptosis by Ning Jin, Yi-yu Qian, Xiao-fei Jiao, Zhen Wang, Xin Li, Wen Pan, Jin-kai Jiang, Pu Huang, Si-yuan Wang, Ping Jin, Qing-lei Gao, Dan Liu, Yu Xia

“…In the context of abundant fatty acids, niraparib elevated intracellular levels of fatty acids and lipid peroxidation, leading to subsequent tumor cell ferroptosis in a p53 and BRCA-independent manner. …”
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Lunar and Martian gravity alter immune cell interactions with endothelia in parabolic flight by Yu Du, Bing Han, Katharina Biere, Nathalie Abdelmalek, Xinyu Shu, Chaoyang Song, Guangyao Chen, Ning Li, Marina Tuschen, Huan Wu, Shujin Sun, Alexander Choukér, Mian Long, Dominique Moser

“…Expression levels of the adhesion markers Mac-1 on THP-1 cells as well as ICAM-1 on HUVECs were found elevated in lunar and Martian gravity, which was aggravated by TNF. …”
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Selected Biomarkers Correlate with the Origin and Severity of Sepsis by Michal Holub, Olga Džupová, Michaela Růžková, Alžběta Stráníková, Eva Bartáková, Jan Máca, Jiří Beneš, Heiko Herwald, Ondřej Beran

“…Our findings suggest that MCP-1, sCD14, IL-6, IL-10, cortisol, and HBP are modulated by the source of sepsis and that elevated MCP-1 and cortisol plasma levels are associated with sepsis-induced organ dysfunction.…”
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Lingguizhugan Decoction Protects against High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease by Alleviating Oxidative Stress and Activating Cholesterol Secretion by Lili Yang, Weili Lin, Colleen A. Nugent, Shijun Hao, Haiyan Song, Tao Liu, Peiyong Zheng

“…DEGs between the NAFLD model and normal groups indicated the elevated peroxisome proliferator-activated receptor (PPAR) and hedgehog signaling pathways in NAFLD rats. …”
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A Comprehensive Exploration of the Fatty Acids Profile, Cholesterol, and Tocopherols Levels in Liver from Laying Hens Fed Diets Containing Nonindustrial Hemp Seed by Youssef Rbah, Yassine Taaifi, Aymane Allay, Kamal Belhaj, Reda Melhaoui, Nadia Houmy, Abdessamad Ben Moumen, Embarek Azeroual, Mohamed Addi, Farid Mansouri, Hana Serghini-Caid, Ahmed Elamrani

“…Moreover, hepatic tocopherol levels are significantly elevated p<0.01 in subjects receiving the HS diet, with the 30% HS group exhibiting the highest tocopherol content. …”
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IgG4-Related Autoimmune Prostatitis: Is It an Unusual or Underdiagnosed Manifestation of IgG4-Related Disease? by María T. Bourlon, Mónica Sánchez-Ávila, Fredy Chablé-Montero, Ricardo Arceo-Olaiz

“…Shared findings included prostate enlargement, LUTS (symptoms that can be confused with BPH), and PSA within normal limits or mild elevations. IgG4-related prostatitis is rarely considered as a preprocedural diagnosis, even in patients with evidence of IgG4-RD. …”
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Plastic harmful ingredients reduce the level of neurofilament light chain protein by Long Li, Xiaoxiu Ma, Junwei Liu, Yongli Wu

“…Finally, the latent profile analysis categorized exposures into high, medium, and low patterns, confirming that higher exposure to plastic hazardous ingredients posed a significant risk factor for elevated NFL levels in the blood. Exposure to plastic hazardous ingredients significantly increases the risk of NFL, the present contributes to early detection and intervention to reduce the incidence of neurodevelopmental disorder.…”
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