Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinica... by Lucas Fornari Laurindo, Lucas Fornari Laurindo, Lucas Fornari Laurindo, Lívia Fornari Laurindo, Victória Dogani Rodrigues, Jéssica da Silva Camarinha Oliveira, Beatriz Leme Boaro, Adriano Cressoni Araújo, Adriano Cressoni Araújo, Elen Landgraf Guiguer, Elen Landgraf Guiguer, Elen Landgraf Guiguer, Claudia Rucco Penteado Detregiachi, Claudia Rucco Penteado Detregiachi, Virgínia Maria Cavallari Strozze Catharin, Virgínia Maria Cavallari Strozze Catharin, Eduardo Federighi Baisi Chagas, Eduardo Federighi Baisi Chagas, Vitor Cavallari Strozze Catharin, Vitor Cavallari Strozze Catharin, Rosa Direito, Sandra Maria Barbalho, Sandra Maria Barbalho, Sandra Maria Barbalho, Sandra Maria Barbalho

“…Diabetes mellitus and dyslipidemia are significant health concerns that elevate the risk of cardiovascular disease and other metabolic disorders, necessitating effective management strategies. …”
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MCP-1-Induced Histamine Release from Mast Cells Is Associated with Development of Interstitial Cystitis/Bladder Pain Syndrome in Rat Models by Jianwei Lv, Yiran Huang, Shiguo Zhu, Ganggang Yang, Yujian Zhang, Jing Leng, Juanjie Bo, Dongming Liu

“…Increased MCP-1 expression in bladder tissue and elevated MCP-1 and histamine levels were observed in the urine of LS+LPS-treated rats. …”
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Deletion of Ovarian Hormones Induces a Sickness Behavior in Rats Comparable to the Effect of Lipopolysaccharide by Hamid Azizi-Malekabadi, Mahmoud Hosseini, Masoume Pourganji, Hoda Zabihi, Mohsen Saeedjalali, Akbar Anaeigoudari

“…In open-field (OP) test, the central crossing number by OVX and Sham-LPS groups were lower than Sham (P<0.001) while there were no significant differences between OVX-LPS and OVX groups. In elevated plus maze (EPM), the percent of entries to the open arm by both OVX and Sham-LPS groups was lower than that of Sham group (P<0.001). …”
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Modelling lateral meltwater flow and superimposed ice formation atop Greenland's near-surface ice slabs by Nicole Clerx, Horst Machguth, Andrew Tedstone, Dirk van As

“…At high elevations on the Greenland ice sheet meltwater percolates and refreezes in place, and hence does not contribute to mass loss. …”
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Trace amine-associated receptors (TAARs)2-9 knockout mice exhibit reduced wakefulness and disrupted REM sleep by Sunmee Park, Jasmine Heu, Gavin Scheldrup, Ryan K. Tisdale, Yu Sun, Meghan Haire, Shun-Chieh Ma, Marius C. Hoener, Thomas S. Kilduff

“…High doses of the TAAR1 agonist RO5256390 increased wakefulness and reduced NREM sleep, while both RO5256390 and the partial agonist RO5263397 suppressed REM sleep in KO mice. Elevated tyrosine hydroxylase levels in the ventral tegmental area suggested dopaminergic involvement in these altered sleep patterns.DiscussionTAAR2-9 modulates sleep/wake states and interacts with TAAR1. …”
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Optimizing heat transfer performance in two-phase closed thermosyphons: A novel design and experimental evaluation by Mohammad Khalili, Seyed Alireza Mostafavi, Seyed Mohammad Mousavi, Hossein Moghadamrad

“…As expected, increasing heat input reduces thermal resistance but also elevates operating temperatures for both TPCTs. Notably, the novel TPCT demonstrates a significant improvement in thermal performance compared to the conventional design, particularly when using ethanol as the working fluid.…”
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A noncanonical role of roX RNAs in autosomal epigenetic repression by Jianjian Li, Shuyang Xu, Zicong Liu, Liuyi Yang, Zhe Ming, Rui Zhang, Wenjuan Zhao, Huipai Peng, Jeffrey J. Quinn, Manyin Wu, Yushan Geng, Yuying Zhang, Jiazhi He, Minghai Chen, Nan Li, Ning-Yi Shao, Qing Ma

“…Correspondingly, X-linked genes display reduced expression, whereas many autosomal genes exhibit elevated expression upon roX loss. Our findings propose a dual role for roX RNAs: activators of X-linked genes and repressors of autosomal genes, achieved through interactions with MSL and PRC complexes, respectively. …”
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The Impact of Antiretroviral Therapy on Liver Function Among Pregnant Women Living with HIV in Co-Existence with and Without Pre-Eclampsia by Kay-Lee E. Strauss, Wendy N. Phoswa, Kabelo Mokgalaboni

“…However, its use has been associated with adverse liver conditions, particularly hepatotoxicity, often marked by elevated liver enzymes (LEEs) as demonstrated by an increased aspartate transferase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) in PWLWHIV on ART. …”
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The Effect of Airway Pressure Release Ventilation on Pulmonary Catheter Readings: Specifically Pulmonary Capillary Wedge Pressure in a Swine Model by Ahmad M. Slim, Shaun Martinho, Jennifer Slim, Eddie Davenport, Luadino M. Castillo-Rojas, Eric A. Shry

“…Ventilator mode was changed to APRV with incremental elevations of CPAP-high from 10 to 35 cm H2O. After a 3-to-5-minute stabilization period, measurements of hemodynamic parameters (PCWP, LAP, and CVP) were recorded at each level of APRV pressure settings. …”
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Strengthened microstructure and mechanical properties of austenitic 316L stainless steels by grain refinement and solute segregation by Yurong Wang, Buwei Xiao, Xiaoyu Liang, Huabei Peng, Jun Zhou, Feng Lin

“…Additionally, the fine grains exhibit predominantly high-angle grain boundaries, and the elevated density of solute segregation in these regions plays a crucial role in contributing to exceptional strength of materials.…”
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α 2-Adrenoceptors: Challenges and Opportunities—Enlightenment from the Kidney by William A. Pettinger, Edwin K. Jackson

“…Further investigations led to the realization that renal α2-AR expression in hypertensive animals is elevated, thus supporting a key role for kidney α2-ARs in the pathophysiology of essential hypertension. …”
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Histone Deacetylation Regulated by KDM1A to Suppress DACT1 in Proliferation and Migration of Cervical Cancer by Lingjuan Zeng, Chunyan Chen, Chanjiao Yao

“…TCGA database showed that cervical cancer tissues had elevated expression of KDM1A and decreased expression of DACT1, which was consistent with the observation in cervical cancer cell lines. …”
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Frontier machine learning techniques for melanoma skin cancer identification and categorization: An in-Depth review by Viomesh Singh, Kavita A. Sultanpure, Harshwardhan Patil

“…Failure to diagnose it at its incipient stages may lead to metastasis, significantly elevating mortality rates. Early detection, however, presents a curative prospect. …”
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Understanding the coupled relationship between regional longevity and physical geographical environment in Hechi, Guangxi, China by Qucheng Deng, Yaqing Liu, Yongping Wei, Wei Liang, Kaixian Zhu, Yonghua Li, Lihai Zhang

“…It is mostly located in rocky mountainous areas with low elevations, small to medium undulations, medium slopes and brown calcareous soils, but is rarely found near the non-ferrous mining industry. …”
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Dietary lipids shape cytokine and leptin profiles in obesity-metabolic syndrome implications: A cross-sectional study. by Sakawrut Poosri, Karani Santhanakrishnan Vimaleswaran, Pattaneeya Prangthip

“…High saturated fat intake was associated with increased IL-6 levels (odds ratio = 2.03, 95% confidence interval [CI] = 1.00-4.11, p < 0.047), whereas high total fat intake elevated leptin levels by 2.14-fold (95% CI = 1.12-4.10, p < 0.021) in participants with obesity.…”
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СLINICAL CHARACTERISTICS OF CHILDREN AND ADOLESCENTS WITH METABOLIC SYNDROME IN KYIV by Maiia Aliusef, Alina Churylina

“…Among the most common complaints were elevated blood pressure, headaches, anxiety, and palpitations. …”
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Scoping review protocol of multicomponent interventions to address cardiometabolic disease risk among Pacific Islander children. by Courtney C Choy, Kate Nyhan, Kima Savusa, Christina Soti-Ulberg, Rochelle K Rosen, Take Naseri, Nicola L Hawley, Mona Sharifi

“…<h4>Materials and methods</h4>Eligible interventions will (1) address CMD risk factors (including but not limited to obesity, hyperglycemia, dyslipidemia, elevated blood pressure, and/or health behaviors) in 2-to-12-year-old Pacific Islander children, and (2) be multi-component (including at least two lifestyle/behavior change strategies to address CMD risk factors). …”
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Adrenoleukodystrophy: Symptoms, Treatment and Newborn Screening. Literature Review and Clinical Case by Laura Regelskytė, Rūta Praninskienė

“…Laboratory testing showed an elevated concentration of very long-chain fatty acids, and genetic testing confirmed the ABCD1 gene mutation. …”
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CLOUD COMPUTING AND FINANCIAL PERFORMANCE OF LISTED DEPOSIT MONEY BANKS IN NIGERIA by Hakeem Olayinka Hakeem Olayinka, Adetumilara Adepeju Dedire-Ampitan

“…The inefficiencies of conventional banking systems and elevated operating costs call for a transition to technology-driven strategies that can enhance profitability and sustainability. …”
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Unlocking prognostic potential: A genomic signature of caloric restriction in patients with epithelial ovarian cancer. by Ori Tal, Tamar Zahavi, Liat Anabel Sinberger, Mali Salmon-Divon

“…<h4>Results</h4>The non-fasting genomic signature, comprising eight genes, demonstrated higher prevalence in primary ovarian tumors compared to normal tissue. Patients with elevated signature expression exhibited reduced overall survival and increased lymphatic invasion. …”
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