Microscopic damage evolution and physical–mechanical behavior of high-temperature red sandstone under varying heating and cooling durations by Mingze Qin, Yue Su, Xiaolan Wang, Huawu Niu, Yifan Zhang, Dongxu Zhang, Nan Qin

“…The findings show that elevated temperatures and prolonged heating significantly alter the microstructure and composition of red sandstone, including pore formation, void development, and structural modifications. …”
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Glycosylated lysosomal membrane protein promotes tissue repair after spinal cord injury by reducing iron deposition and ferroptosis in microglia by Fangru Ouyang, Meige Zheng, Jianjian Li, Jinxin Huang, Jianan Ye, Jingwen Wang, Yuanzhe Zhao, Fangli Shan, Ziyu Li, Shuishen Yu, Fei Yao, Dasheng Tian, Li Cheng, Juehua Jing

“…Concurrently, microglia exhibited elevated expression of the iron-storage protein ferritin and were found to undergo ferroptosis between 7 and 28 dpi. …”
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Dasatinib-Induced Pulmonary Arterial Hypertension Treated with Upfront Combination Therapy by Makoto Nishimori, Tomoyuki Honjo, Kenji Kaihotsu, Naohiko Sone, Sachiko Yoshikawa, Junichi Imanishi, Kazuhiko Nakayama, Noriaki Emoto, Masanori Iwahashi

“…Echocardiography revealed interventricular septal compression and elevated peak tricuspid regurgitation pressure gradient of 66.7 mmHg indicating severe pulmonary hypertension. …”
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Cerium-based nanoplatform for severe acute pancreatitis: Achieving enhanced anti-inflammatory effects through calcium homeostasis restoration and oxidative stress mitigation by Tingyi Luo, Yujing Tang, Wangcheng Xie, Zhilong Ma, Jian Gong, Yonggui Zhang, Tingsong Yang, Xuyang Jia, Jia Zhou, Zhengyu Hu, Lin Han, Qigang Wang, Zhenshun Song

“…Current therapeutic approaches, including antibiotics, trypsin inhibitors, fasting, rehydration, and even continuous renal replacement therapy, yield limited clinical management efficacy. Abnormally elevated calcium levels and reactive oxygen species (ROS) overproduction by damaged mitochondria are key factors in the inflammatory cascade in SAP. …”
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Therapeutic potential of monomethyl fumarate and aluminum ion combination in alleviating inflammation and oxidative stress in psoriasis by Hang Han, Guojiang Zhang, Yuanyuan Yang, Chenxi Li, Xiandeng Li, Ling Zhong, Zan Chen, Jianxia Xiong, Tao Cai, Lingjuan Zhang, Xiao Zhang, Qinjian Zhao

“…Concurrently, the treatment elevates Th2 cytokine secretion, thereby increasing the anti-inflammatory response in HaCaT cells. …”
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Environmental biocontamination by SARS-CoV-2 Virus in the hospital setting by M Espejo Mambié, D San Jose-Saras, C Bischofberger Valdés, C Díaz-Agero Pérez, JC Galán Montemayor, L Martínez-García, M Abreu Di-Berardino, P Moreno-Nunez, J Vicente-Guijarro, J.M Aranaz-Andrés

“…High dependency and elevated temperatures seemed to indicate a higher risk of environmental biocontamination. …”
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An Investigation Into a Lightweight Safety Helmet Detection Approach Utilizing the MSS-YOLO Framework by Bing Zeng, Zhanpeng Liao, Yu Zhou, Dilin He, Zhihao Zhou, Kexin Yi, Yuwen Li, Xiaopin Yang, Yunmin Xie

“…The experimental outcomes reveal that compared to its predecessor, the proposed algorithm achieves a significant reduction in parameters from 61.949M to 13.547M and in computational load from 66.171G to 7.895G, while simultaneously elevating mAP@0.5 from 81.99% to 91.20%. This demonstrates the algorithm’s capability to maintain high detection accuracy while drastically minimizing its parameter size and computational overhead.…”
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How to Distinguish Patients with pSS among Individuals with Dryness without Invasive Diagnostic Studies by Agata Sebastian, Maciej Sebastian, Maria Misterska-Skóra, Patryk Woytala, Katarzyna Jakuszko, Piotr Wiland

“…In the pSS group, anaemia (p=0.0085), lymphocytopenia (p=0.0006), elevated ERS (p=0.001), higher RF titer, and ANA antibodies were noted. …”
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Network pharmacology and experimental verification reveal the mechanism of Qingfei Tongluo mixture in treating pulmonary fibrosis by Ying Zhou, Wenlong Wang, Wanping Zhu, Tingting Cai, Nannan Wang, Xia Liu, Wenmin Wang, Kequn Chai

“…Immunohistochemistry showed elevated FTO and TGF-β1 levels in PF tissues. Animal experiments demonstrated that QTm improved alveolar structure, reduced interstitial lesions, and enhanced lung function while decreasing hydroxyproline content and the expression of FTO and TGF-β1 proteins. …”
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The Relationship between Branched-Chain Amino Acid Related Metabolomic Signature and Insulin Resistance: A Systematic Review by Xue Zhao, Qing Han, Yujia Liu, Chenglin Sun, Xiaokun Gang, Guixia Wang

“…These factors might not only contribute to the elevated BCAA level but also show obvious associations with insulin resistance. …”
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Room temperature CRISPR diagnostics for low-resource settings by Eric A. Nalefski, Selma Sinan, Jason L. Cantera, Anastasia G. Kim, Remy M. Kooistra, Rafael E. Rivera, Jordyn P. Janshen, Sanchita Bhadra, Joshua D. Bishop, Andrew D. Ellington, Ilya J. Finklestein, Damian Madan

“…Abstract Maintaining elevated reaction temperatures and multi-step sample preparations increases the costs and complexity of diagnostics, impeding their deployment in low-resource settings. …”
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Microstructural Analysis and Radiological Characterization of Alkali-Activated Materials Based on Aluminosilicate Waste and Metakaolin by Nataša Mladenović Nikolić, Aleksandar Kandić, Jelena Potočnik, Nemanja Latas, Marija Ivanović, Snežana Nenadović, Ljiljana Kljajević

“…In this paper, we evaluate physico-chemical properties, microstructure, and radiological environmental impacts when wastes that contain elevated levels of naturally occurring radionuclides (NORs) such as fly ash and wood ash are made into “green cements” such as AAMs. …”
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Craniofacial Brown Tumor in Patients with Secondary Hyperparathyroidism to Chronic Renal Failure: Report of Two Cases in Cipto Mangunkusumo Hospital by Diani Kartini, Maria K. Siswiandari, Gunawan Wibisana, Erwin D. Yulian, Ahmad Kurnia, Sonar S. Panigoro, Azdi Z. Albar, Muchlis Ramli

“…Laboratory workup showed elevated parathormone or PTH (3.391 pg/mL and >5.000 pg/mL). …”
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A Millimeter-Wave Single-Bit Reconfigurable Intelligent Surface With High-Resolution Beam-Steering and Suppressed Quantization Lobe by Aditya S. Shekhawat, Bharath G. Kashyap, Russell W. Raldiris Torres, Feiyu Shan, Georgios C. Trichopoulos

“…The prototype is designed to operate at 27.2 GHz and perform electronic beam steering in ±60° in both azimuth and elevations planes. A quantization lobe reduction of more than 10 dB is achieved with the proposed technique and the surface is well suited for mmWave 5G communication scenarios to enhance signal coverage and signal-to-noise ratio.…”
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Vessel strike encounter risk model informs mortality risk for endangered North Atlantic right whales along the United States east coast by Hannah Blondin, Lance P. Garrison, Jeffrey D. Adams, Jason J. Roberts, Caroline P. Good, Meghan P. Gahm, Niki E. Lisi, Eric M. Patterson

“…Abstract Vessel strikes are a critical threat to endangered North Atlantic right whales (Eubalaena glacialis), significantly contributing to their elevated mortality. Accurate estimates of these mortality rates are essential for developing effective management strategies to aid in the species’ recovery. …”
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Calcific Uremic Arteriolopathy: A Case Series and Review from an Inner-City Tertiary University Center in End-Stage Renal Disease Patients on Renal Replacement Therapy by Mohamed Omer, Zeenat Yousuf Bhat, Nanette Fonte, Nashat Imran, James Sondheimer, Yahya Osman‐Malik

“…The parathyroid hormone level (PTH) was elevated in 22 patients. Fifteen patients were diagnosed 2 weeks or more prior to skin lesion onset. …”
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Examining the Impact of Adverse Weather on Travel Time Reliability of Urban Corridors in Shanghai by Yajie Zou, Ting Zhu, Yifan Xie, Linbo Li, Ying Chen

“…., peak hours and off-peak hours on elevated expressway, peak hours and off-peak hours on arterial road) were considered in the TTR analysis. …”
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Lactic acid contributes to the emergence of depression-like behaviors triggered by blue light exposure during sleep by Yinhan Li, Xinhui Zou, Ying Ma, Jiaqi Cheng, Xiangmin Yu, Wenya Shao, Fuli Zheng, Zhenkun Guo, Guangxia Yu, Siying Wu, Huangyuan Li, Hong Hu

“…Metabolomics and colorimetric analyses revealed elevated levels of lactic acid in the cerebrospinal fluid and lateral habenula (LHb) of rats with depression-like behaviors induced by BLS. …”
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Lithium-doped calcium silicate cement regulates the immune microenvironment and promotes M2 macrophage polarization for enhancing bone regeneration by Yen-Hong Lin, Cheng-Yu Chen, Kun-Hao Chen, Ting-You Kuo, Tsung-Li Lin, Ming-You Shie

“…The presence of Li in the cement also significantly improved the osteogenic differentiation of WJMSCs, as evidenced by elevated levels of alkaline phosphatase and osteocalcin expression. …”
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Next generation thiazolyl ketone inhibitors of cytosolic phospholipase A2 α for targeted cancer therapy by Felicity J. Ashcroft, Asimina Bourboula, Nur Mahammad, Efrosini Barbayianni, Astrid J. Feuerherm, Thanh Thuy Nguyen, Daiki Hayashi, Maroula G. Kokotou, Konstantinos Alevizopoulos, Edward A. Dennis, George Kokotos, Berit Johansen

“…Consistent with these results, we show that elevated intracellular reactive oxygen species and activating transcription factor 4 target gene expression precede cell death in AVX420-sensitive T-cell acute lymphoblastic leukemia cells. …”
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