Unmasking health determinants and health outcomes for urban First Nations using respondent-driven sampling by J Smylie, M Firestone, S Maracle, M Spiller, P O'Campo

“…Common chronic diseases included arthritis, hypertension, diabetes and chronic obstructive pulmonary disease and rates of emergency room access were elevated.Conclusions RDS is an effective sampling method in urban Aboriginal contexts as it builds on existing social networks and successfully identified a population-based cohort. …”
Get full text

Degradation Behavior of Concrete after Freeze-Thaw Cycles and Then Exposure to High Temperatures by Qifang Xie, Liujie Yang, Fangzheng Hu, Wenming Hao, Shenghua Yin, Lipeng Zhang

“…(ii) After freeze-thaw cycles, the relative strengths and elastic modulus of the concrete specimens significantly degrade compared with those of the unfrozen ones at same temperatures. (c) At elevated number of freeze-thaw cycles and exposure temperatures, the peak strain of the concrete increases gradually. …”
Get full text

Numerical heat transfer analysis considering thermal contact conductance between rough reciprocating sliding surfaces by Yuwei Liu, Jiasong Yang, Zhiqiang Guo, Yanpeng Yuan, Weizheng Zhang, Sichuang Wanyan

“…The frictional heat generated leads to elevated surface temperatures, which markedly influence the reliability and service life of friction pairs. …”
Get full text

The Temporal Pattern of Arterial Stiffness during Aging: A Large-Scale Cross-Sectional Study by Zhengli Tang, Yuanyuan Lu, Yiming Hao, Robert Morris, Di Kang, Fang Wang, Lin Fan, Weijian Wang, Yiqin Wang, Feng Cheng

“…Many underlying physiological conditions such as hyperlipidemia, hypertension, diabetes, and hyperglycemia have previously been shown to elevate baPWV and contribute to the decline of arterial function. …”
Get full text

Myelofibrosis-Associated Lymphoproliferative Disease: Retrospective Study of 16 Cases and Literature Review by A. Etienne, B. Gruson, D. Chatelain, R. Garidi, B. Royer, H. Sevestre, J. P. Marolleau, G. Damaj

“…B-symptoms are more frequent at diagnosis and more patients presented with an elevated LDH level. JAK-2 was negative in the 10 patients analysed. …”
Get full text

Changes in Serum Natriuretic Peptide Levels after Percutaneous Closure of Small to Moderate Ventricular Septal Defects by Yuksel Kaya, Ramazan Akdemir, Huseyin Gunduz, Sani Murat, Orhan Bulut, İbrahim Kocayigit, M. Bulent Vatan, M. Akif Cakar, Ekrem Yeter, Harun Kilic, Mustafa Tarik Agac, Zeydin Acar

“…Brain Natriuretic Peptide levels are elevated in patients with ventricular septal defects as compared to controls. …”
Get full text

Ectopic ACTH Syndrome Emerging 5 Years after the Diagnosis of Neuroendocrine Tumor by Minghao Liu, Diane Hamele-Bena, John Ausiello, Gabrielle Page-Wilson

“…Plasma levels of peptides which have been associated with EAS, Agouti-related peptide (AgRP) and the ACTH precursors POMC (31-kDa) and pro-ACTH (22-kDa), were elevated. Metyrapone was initiated, but hypercortisolism persisted and the patient succumbed to pneumonia shortly after presentation. …”
Get full text

Expression of Toll-Like Receptors 2 and 4 and Related Cytokines in Patients with Hepatic Cystic and Alveolar Echinococcosis by Tuerhongjiang Tuxun, Hai-Zhang Ma, Shadike Apaer, Heng Zhang, Amina Aierken, Yu-Peng Li, Ren-Yong Lin, Jin-Ming Zhao, Jin-Hui Zhang, Hao Wen

“…Median levels of TLR2 mRNA in AE and CE groups were significantly elevated as compared with that in healthy control group. …”
Get full text

Case of Metastatic Canine Transmissible Venereal Tumor in a Dog: Clinical and Cytological Evaluation by Olanrewaju Samuel Olaifa, Abdulrauf Adekunle Usman, Taiwo Kemi Adebiyi, Bamidele Nyemike Ogunro, Adah Osereime, Richard Edem Antia, Favour Akinfemi Ajibade, Ojuolape Adeyemi Adeshubomi, Toluwalase Oluwatimilehin Soneye

“…Hematological tests revealed non-regenerative anemia and elevated white blood cell count, while cytological examination identified neoplastic round cells with high nucleus-to-cytoplasm ratios and mitotic figures. …”
Get full text

The Neuro-Inflammatory-Vascular Circuit: Evidence for a Sex-Dependent Interrelation? by Catherine Gebhard, Catherine Gebhard, Susan Bengs, Susan Bengs, Achi Haider, Achi Haider, Michael Fiechter, Michael Fiechter, Michael Fiechter

“…However, strong associations with psychological stress, obesity or elevated inflammatory biomarkers with adverse cardiovascular outcomes in women have been identified in various studies. …”
Get full text

Ankrd1 as a potential biomarker for the transition from acute kidney injury to chronic kidney disease by Hailin Li, Lemei Hu, Changqing Zheng, Ying Kong, Ming Liang, Quhuan Li

“…Compared to the sham-operated group, the expression of Ankrd1 in mice increased at 0.5 days post-reperfusion, peaked at day 1, and remained significantly elevated up to 60 days. This study indicated that the upregulation of Ankrd1 was positively associated with the progression from AKI to CKD and may potentially serve as a valuable biomarker for this transitional process.…”
Get full text

Epilepsy and brain health: a large prospective cohort study by Dan-Dan Zhang, Zi-Yi Wang, Ya-Ru Zhang, Pei-Yang Gao, Wei Zhang, Yan Fu, Hao-Chen Chi, Li-Yun Ma, Yi-Jun Ge, Xiao-Yu He, Jia You, Wei Cheng, Jian-Feng Feng, Lan Tan, Jin-Tai Yu

“…The risk of neurological diseases and psychiatric disorders was significantly elevated in the epilepsy population during the 17-year follow-up period, according to the longitudinal analysis. …”
Get full text

Polystyrene microplastics disrupt adrenal steroid synthesis in male mice via mitochondrial dysfunction by Ying Xiong, Zhe Chen, Hanmin Xiang, Yi Liu, Yanlin Wang

“…In vitro, these occurrences coincided with an elevated rate of cell apoptosis observed in adrenocortical cells following exposure to PS-MPs. …”
Get full text

Exploring the physiological, biochemical, and enzymatic responses of Vigna mungo varieties to Mungbean Yellow Mosaic India Virus (MYMIV) infection by Subham Dutta, Poly Saha, Mritunjoy Barman, R. Poorvasandhya, Moumita Panda, Tarique Ahmed, Thomas Wilbur Davis, Bulbul Ahmed, Mudagadde G. Deeksha, Jayanta Tarafdar

“…Enzymatic analysis showed that resistant genotypes had elevated POD, SOD, and PAL activities, supporting their enhanced defense mechanisms. …”
Get full text

Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization by Ruofei Zhang, Yanfang Shen, Xiaoying Zhou, Jianru Li, Hanqing Zhao, Zixia Zhang, Jun Zhao, Hongjun Jin, Shuanshuan Guo, Hui Ding, Guohui Nie, Zhe Zhang, Ying Wang, Xiyun Yan, Kelong Fan

“…Nanozymes, nanomaterials with catalase-like activity, have emerged as a promising strategy for radiosensitization by converting elevated hydrogen peroxide in the tumor microenvironment into oxygen. …”
Get full text

Cytochrome P450 Metabolism of Betel Quid-Derived Compounds: Implications for the Development of Prevention Strategies for Oral and Pharyngeal Cancers by Che-Yi Lin, Tien-Szu Pan, Chun-Chan Ting, Shih-Shin Liang, Shu-Hung Huang, Hsiu-Yueh Liu, Edward Cheng-Chuan Ko, Chung-Wei Wu, Jen-Yang Tang, Ping-Ho Chen

“…Betel quid (BQ) products, with or without tobacco, have been classified by the International Agency for Research on Cancer (IARC) as group I human carcinogens that are associated with an elevated risk of oral potentially malignant disorders (OPMDs) and cancers of the oral cavity and pharynx. …”
Get full text

Impact of polyvinyl chloride nano-plastics on the biochemical status of Oreochromis niloticus under a predicted global warming scenario by Ahmed Mohamed Soliman, Ayman S. Mohamed, Amr A. Abdel-Khalek, Shereen R. Badran

“…After 4 days, the biochemical response of fish exposed to PVC-NPs and elevated temperatures showed a significant increase in the levels of plasma total proteins, albumin, globulin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatinine, and uric acid. …”
Get full text

Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis by Sriram Vijayraghavan, Thomas Blouin, James McCollum, Latarsha Porcher, François Virard, Jiri Zavadil, Carol Feghali-Bostwick, Natalie Saini

“…We hypothesize that the inflammation and immune response associated with systemic sclerosis can trigger DNA damage, leading to elevated somatic mutagenesis, a hallmark of pre-cancerous tissues. …”
Get full text

Development and validation of a prognostic signature of breast cancer based on drug absorption, distribution, metabolism and excretion (ADME)-related genes by Zhixuan Wu, Yangyang Guo, Liangchen Qu, Xiaowu Wang, Hewei Zhang

“…Additionally, the analysis of the immune microenvironment revealed that the ImmuneScores of the low-risk group were elevated. The variation in both the infiltration of immune cells and the expression of immune-related genes in the tissues differed among the two groups. …”
Get full text

Increased Frequency of Circulating Follicular Helper T Cells in Patients with Rheumatoid Arthritis by Jie Ma, Chenlu Zhu, Bin Ma, Jie Tian, Samuel Essien Baidoo, Chaoming Mao, Wei Wu, Jianguo Chen, Jia Tong, Min Yang, Zhijun Jiao, Huaxi Xu, Liwei Lu, Shengjun Wang

“…Taken together, these findings have shown that the increased frequency of circulating Tfh cells is correlated with elevated levels of anti-CCP antibody, indicating the possible involvement of Tfh cells in the disease progression of RA.…”
Get full text