A New Regional Background Atmospheric Station in the Yangtze River Delta Region for Carbon Monoxide: Assessment of Spatiotemporal Characteristics and Regional Significance by Yi Lin, Shan Li, Yan Yu, Meijing Lu, Bingjiang Chen, Yuanyuan Chen, Kunpeng Zang, Shuo Liu, Bing Qi, Shuangxi Fang

“…The winter CO concentration remained elevated but peaked in March in the early spring due to the combined effect of regional emissions within the YRD and transportation impacts of North China and Southeast Asia sources. …”
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Predictive nomogram for postoperative lower-limb deep vein thrombosis in patients undergoing endoscopic endonasal surgery during hospitalization: a retrospective cohort study by Hai Peng, Ruofei Yuan, Zhe Zhang, Ying Wang, Xingchao Wang, Bo Wang, Peng Li

“…Significant predictors included older age, intraoperative bleeding, female gender, prolonged surgery duration, elevated postoperative APTT and D-dimer levels, and disturbance of consciousness. …”
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Defining Nocturnal Polyuria in Adolescents by Tasmia Promi, Anthony Brooks, Gulzhan Tologonova, Marie-Claire Roberts, Sarita Dhuper, Meseret Tena, Oluwatoyin Bamgbola, Monique Hanono, Jeffrey P. Weiss, Karel Everaert, Tine DeBacker, Thomas F. Monaghan, Louis Salciccioli, Stephen Wadowski, Elka Jacobson-Dickman, Jason M. Lazar

“…On multivariable logistic regression with variables of sex, obesity, and elevated blood pressure, adding NUP as a categorical variable maximally increased the predictive value of the model upon utilizing a cutoff of 50 ml/h, increasing the R2 from 0.491 to 0.683. …”
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The role of Mitofusin-1 and Mitofusin-2 in periodontal disease: a comprehensive review by Sudhir R. Varma, Sudhir R. Varma, Omar H. A. A. Ani, Jayaraj K. Narayanan, Jayaraj K. Narayanan, Asok Mathew, Asok Mathew

“…Decreased levels of these proteins were related to elevated oxidative stress, inflammation, and increased mitochondrial dysfunction in periodontal tissues. …”
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Characteristics Defining Broccoli Cultivars from Different Seed Producers by Elena Ordiales, Domingo J. Iglesias, María Victoria Alarcón, Lorena Zajara, Jesús Gil, Juan Ignacio Gutiérrez, Julio Salguero

“…Broccoli (Brassica oleracea L. var. italica) is currently considered a main vegetable food in the markets due to its high nutritional value, containing elevated levels of phytochemicals widely described to have beneficial effects against cancer and other illnesses. …”
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Chronic kidney disease and inflammatory cytokines in rheumatoid arthritis: a potential pathogenic link by Hironari Hanaoka, Takumi Aoki, Taiji Kosaka, Shoichi Yoshinaga, Akiko Shibata, Ryota Sakai, Takahiko Kurasawa, Koichi Amano

“…Inflammatory cytokines, notably interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and IL-1, play significant roles in the pathogenesis of both RA and CKD, promoting systemic inflammation and renal impairment. Elevated levels of various cytokines have been detected in the plasma and urine of CKD patients, and they raise morbidity and mortality rates, even during early disease stages. …”
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Intrahepatic Cholestasis of Pregnancy Leading to Severe Vitamin K Deficiency and Coagulopathy by Maria Maldonado, Ali Alhousseini, Michael Awadalla, Jay Idler, Robert Welch, Karoline Puder, Manasi Patwardhan, Bernard Gonik

“…Laboratory work-up showed severe coagulopathy with Prothrombin Time (PT) of 117.8 seconds, International Normalized Ratio (INR) of 10.34, and elevated transaminases suggestive of intrahepatic cholestasis of pregnancy. …”
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Biotechnology breakthroughs: Revolutionizing oral cancer treatment by Safin Hussein, Karzan Qurbani, Haider Hamzah, Seenaa Ali, Sirwan Khalid Ahmed

“…Achieving this goal requires collaborative efforts and continued exploration to optimize treatment effectiveness and elevate patient survival rates.…”
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New anti-friction self-lubricating composite based on EP975 nickel alloy powder with CaF2 solid lubricant – Thermal and dilatometric behavior by Adam Kurzawa, Mateusz Stachowicz, Maciej Roszak, Tetiana Roik, Oleg Gavrysh, Iulia Maistrenko, Krzysztof Jamroziak, Mirosław Bocian, Grzegorz Lesiuk

“…Antifriction properties showed the advantages of the studied composite (improved friction coefficient and friction wear at elevated temperature). The authors analyzed the thermal, mechanical, wear structural and chemical phenomena of the new high-temperature antifriction composite developed to operate at high temperatures (800˗900 °C). …”
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Diagnosis of Vitreoretinal Aspergillosis with Transvitreal Retinochoroidal Biopsy by Krishi Peddada, Nida M. Khan, Jascha Rubin, Haykanush Zakaryan, Yaobin Liu, Nikolay Popnikolov, Roshun Sangani, Weiye Li

“…Transvitreal retinochoroidal biopsy was performed in an elevated area of the retina. The biopsy helped rule out malignancy and showed acute-angle, septate, branching hyphae characteristic of Aspergillus fumigatus. …”
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The effect of silver nitrate on the alkaline phosphatase activity, TNF and IL-10 gene expression; Experimental and computational studies by Nader jadid, Ali Asghar Moshtaghie, Hashem Nayeri, Masoud Foladgar, Maryam Ostadsharif

“…Additionally, gel filtration chromatography with Sephacryl S300 demonstrated that serum from silver nitrate-treated groups exhibited a significantly elevated concentration of high molecular weight alkaline phosphatase compared to control groups. …”
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Aortic Dissection in a Healthy Male Athlete: A Unique Case with Comprehensive Literature Review by Balraj Singh, Jennifer M. Treece, Ghulam Murtaza, Samit Bhatheja, Steven J. Lavine, Timir K. Paul

“…Physical exam was significant for elevated jugular venous pressure, muffled heart sounds, and cold extremities with diminished pulses in upper and absent pulses in lower extremities. …”
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Robust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity by Jisun So, Olivia Strobel, Jamie Wann, Kyungchan Kim, Avishek Paul, Dominic J Acri, Luke C Dabin, Jungsu Kim, Gang Peng, Hyun Cheol Roh

“…Specifically, we identify a key molecular feature of dysfunctional hypertrophic adipocytes, a global shutdown in gene expression, along with elevated stress and inflammatory responses. Furthermore, our differential gene expression analysis reveals distinct contributions of adipocyte subpopulations to the overall pathophysiology of adipose tissue. …”
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Lower Limb Metaphyseal Bone Is Lost in Men with Coeliac Disease and Does Not Relate to Parathyroid Status by Michael W. J. Davie, Sally F. Evans, Christopher A. Sharp

“…Low BMD lower limb regions comprising mostly trabecular bone occur early in CD and in the absence of elevated PTH or increased bone resorption. Low BMD is associated with low body weight.…”
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KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC by Jinghan Li, Daiwang Shi, Siyi Li, Xiang Shi, Yu Liu, Yi Zhang, Gebang Wang, Chenlei Zhang, Tian Xia, Hai-long Piao, Hong-Xu Liu

“…Moreover, the combination of elevated KEAP1 expression with anti-PD-L1 immunotherapy resulted in a synergistic effect on both tumor growth and cytotoxic T-cell activation. …”
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In silico approaches for developing sesquiterpene derivatives as antagonists of human nicotinic acetylcholine receptors (nAChRs) for nicotine addiction treatment by Taufik Muhammad Fakih, Aden Dhana Rizkita, Sintia Ayu Dewi, Muchtaridi Muchtaridi

“…These compounds demonstrated robust interactions with the nAChRÿ3 receptor, as evidenced by elevated molecular mechanics general surface area (MM/GBSA) values (ΔG Bind = Dihydroxyeudesmene: −36.45 kcal/mol, Gibberodione: −36.51 kcal/mol, and Germacrene-E: −36.51 kcal/mol). …”
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Effect of Different Stages of Chronic Kidney Disease and Renal Replacement Therapies on Oxidant-Antioxidant Balance in Uremic Patients by Hadja Fatima Tbahriti, Abbou Kaddous, Malika Bouchenak, Khedidja Mekki

“…The evolution of CKD was associated with elevated OS. HD accentuates lipid, while PD aggravates protein oxidation. …”
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Interprofessional approach to personalized medication management and therapy optimization in IBD care by Daniel Fleischmann, Benedicta Binder, Muriel Huss, Tanja Elger, Claudia Wolf, Johanna Loibl, Hauke Christian Tews, Arne Kandulski, Stephan Schmid, Martina Müller, Alexander Kratzer

“…A considerable number of patients with chronic inflammatory bowel diseases (IBD) are required to manage extensive polypharmaceutical regimes, which significantly elevates the risk of drug–drug interactions. Also, the disease’s impact often leads to the consumption of additional self-medication by the patients such as naturopathic remedies to alleviate disease-induced suffering and nutritional supplements to compensate for malabsorption syndromes inherent to the condition. …”
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Folate alleviated skin inflammation and fibrosis resulting from impaired homocysteine metabolism by Jiefeng Huang, Wuyan Lu, Shenli Zhao, Zixin Cai, Linxiao Li, Zihao Hu, Yu Jiang, Jinyi Deng, Yiming Tang, Chenzhang Shi, Chen Wang, Guangpeng Liu, Shuaijun Li

“…Fibrotic skin fibroblasts exhibited elevated levels of Hcy due to the downregulation of catabolism genes CBS and MTR. …”
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Design and implementation of a solar powered kit for measurement and logging of environmental parameters using the SEN55 sensor by J. Nchi Muhvu, M.D. Fendji, C.M. Ekengoue

“…Muea showed higher PM and humidity levels, exceeding recommended thresholds, while Awae-Ewangkang demonstrated better air quality but elevated humidity. Investigations highlighted the severe air pollution caused by traditional lighting sources such as kerosene lamps and candles. …”
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