Research on the Lateral Resistance of Column Frames in the Tang Dynasty: A Case Study of the Straight Tenon Joints Under Varied Vertical Load Levels by Xiang Gan, Fanxu Kong, Ziyi Wang, Xinran Li, Tingyu Meng, Jiayang Wang, Qin Wang, Jinqiu Xie, Zeli Que

“…With increasing vertical loads, the maximum restoring force and stiffness of the column frame are elevated, enhancing the structure’s energy dissipation capacity and partially mitigating its stiffness degradation. …”
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Air Pollution and Watershed Research in the Central Sierra Nevada of California: Nitrogen and Ozone by Carolyn Hunsaker, Andrzej Bytnerowicz, Jessica Auman, Ricardo Cisneros

“…We report on two years of research in the central Sierra Nevada of California, a semi-arid forest at elevations of 1100–2700 m. Information on O3 and N air pollutants is obtained from a network of 18 passive samplers. …”
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Strontium–Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment by Wenxiu Yuan, Jiaqi Liu, Zhenzhen Zhang, Chengxinyue Ye, Xueman Zhou, Yating Yi, Yange Wu, Yijun Li, Qinlanhui Zhang, Xin Xiong, Hengyi Xiao, Jin Liu, Jun Wang

“…Here, we developed an optimized system that boosts the yield of SMSC-derived exosomes (SMSC-EXOs) and improves their miRNA profiles with an elevated proportion of beneficial miRNAs, while reducing harmful ones by pretreating SMSCs with Sr. …”
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Postbiotics From Lactobacillus Johnsonii Activates Gut Innate Immunity to Mitigate Alcohol‐Associated Liver Disease by Ruopeng Yin, Tao Wang, Jingzu Sun, Huanqin Dai, Yuting Zhang, Ningning Liu, Hongwei Liu

“…Specifically, HKLJ is found to upregulate the expression of intestinal lysozymes, thereby enhancing the production of immunoregulatory substances from gut bacteria, which subsequently activated the Nucleotide‐binding oligomerization domain 2 (NOD2)‐interleukin (IL‐23)‐IL‐22 innate immune axis. The elevated IL‐22 upregulated the antimicrobial peptide synthesis to maintain intestinal homeostasis and moreover activated the Signal transducer and activator of Transcription3 (STAT3) pathway in the liver to facilitate the repair of hepatic injuries. …”
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Maternal Serum Cytokine Concentrations in Healthy Pregnancy and Preeclampsia by Toni Spence, Philip J. Allsopp, Alison J. Yeates, Maria S. Mulhern, J. J. Strain, Emeir M. McSorley

“…Proinflammatory cytokines (TNF-α, IFN-γ, IL-2, IL-8, and IL-6) are significantly elevated in preeclampsia. More research is required to determine the usefulness of using cytokines, particularly IL-10, as early biomarkers of pregnancy health.…”
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Histological assessment of thermal damage in porcine muscle induced by monopolar electrosurgical cutting devices during manual and robotic testing by Elzbieta Ewertowska, Vincent J. Casey, Robert Whiting, Micheal Burke, Laura Frey, Paul Sheridan, Ben Row, Bryan Deeny, Laoise M. McNamara

“…The extent of tissue necrosis due to temperature elevations is dependent on the cutting technique, device design, coating properties and power settings, but the influence of these parameters is not fully understood. …”
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Single-cell sequencing elucidates the mechanism of NUSAP1 in glioma and its diagnostic and prognostic significance by Meng-Yu Zhao, Zhao-Lei Shen, Hongzhen Dai, Wan-Yan Xu, Li-Na Wang, Yu- Gu, Jie-Hui Zhao, Tian-Hang Yu, Cun-Zhi Wang, Jia-feng Xu, Guan-Jun Chen, Dong-Hui Chen, Wen-Ming Hong, Wen-Ming Hong, Fang Zhang

“…Notably, differentiation trajectory analysis identified NUSAP1 as a key marker for the terminal subpopulation. We found that elevated NUSAP1 expression correlated with poor prognosis, prompting further investigation of its functional role through both cellular and animal studies.ConclusionsNUSAP1-based risk models hold potential as predictive and therapeutic tools for personalized glioma treatment. …”
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Anxiolytic, Antidepressant, and Anticholinesterase Effects of Essential Oil from <i>Myrcia sylvatica</i> (G.Mey.) DC by Antônio Quaresma da Silva Júnior, Mariana Maciel Garcia, Wanderson da Silva Farias, Deise Juliane dos Anjos de Sousa, Adenilson de Sousa Barroso, Pablo Luis Baia Figueiredo, Gabriela B. dos Santos, Ricardo Bezerra de Oliveira, Rosa Helena Veras Mourão

“…The anxiolytic activity was assessed using the elevated plus maze and light–dark box tests, while antidepressant activity was evaluated using the tail suspension and forced swimming tests. …”
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Discordance in Couples Pregnancy Intentions and Breastfeeding Duration: Results from the National Survey of Family Growth 2011–2013 by Jordyn T. Wallenborn, Gregory Chambers, Elizabeth P. Lowery, Saba W. Masho

“…Parental disagreement in pregnancy intention elevates the risk of adverse health events for mother and child. …”
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The association between salivary oxytocin, age, and puberty in children with and without OCD by Anna-Rosa Cecilie Mora-Jensen, Line Katrine Harder Clemmensen, Manja Gersholm Grønberg, Eli R. Lebowitz, Daniel S. Quintana, Niklas Rye Jørgensen, Charlotte Sewerin Larsen, Lasse Kristoffer Bak, Gitte Lund Christensen, Linea Pretzmann, Valdemar Uhre, Sofie Heidenheim Christensen, Camilla Uhre, Nicoline Løcke Jepsen Korsbjerg, Christine Lykke Thoustrup, Julie Hagstrøm, Melanie Ritter, Kerstin Jessica Plessen, Anne Katrine Pagsberg, Nicole Nadine Lønfeldt

“…Our findings do not suggest elevated oxytocin concentrations in pediatric OCD. …”
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The Associations Between Sleep Duration and Various Metabolic Health Indices Among Adults in the United States: A Multivariate Analysis of Variance (MANOVA) Using National Health a... by Shuo Feng, Jeong-Hui Park, Qiyue Zhang, Ping Ma, Jung-Min Lee, Jong Cheol Shin

“…Conclusion: The study highlights the detrimental associations of both sleep deprivation and short sleep with metabolic health, such as elevated blood pressure and waist circumference, and lowered HDL cholesterol. …”
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Patients with Ankylosing Spondylitis and Low Disease Activity because of Anti-TNF-Alpha Therapy Have Higher TRAIL Levels Than Controls: A Potential Compensatory Effect by Fernanda Genre, Raquel López-Mejías, Javier Rueda-Gotor, José A. Miranda-Filloy, Begoña Ubilla, Beatriz Carnero-López, Natalia Palmou-Fontana, Inés Gómez-Acebo, Ricardo Blanco, Trinitario Pina, Rodrigo Ochoa, Carlos González-Juanatey, Javier Llorca, Miguel A. González-Gay

“…Anti-TNF-α infusion did not change TRAIL levels after 120′. Conclusion. Elevated TRAIL levels in AS patients may be the result of a compensatory mechanism to reduce CV risk in these patients.…”
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Glycogen Storage Disease Type IX in a 6-year-old Male: A Case Report by Shahab Noorian, Hossein Moravej, Zhila Afshar, Afagh Hassanzadeh Rad, Setila Dalili

“…Case Presentations: A case study of a 6-year-old boy with GSD type IX is presented, highlighting recurrent hypoglycemia, growth delay, and elevated liver enzymes. Genetic testing confirmed a PHKA2 mutation, and the patient’s management included frequent meals, cornstarch therapy, and regular liver function monitoring. …”
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Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review by Michalina Jurkiewicz, Karolina Siembab, Julia Białeta, Katarzyna Rowińska, Agnieszka Napieralska, Wiktor Garbarczyk, Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Wiktoria Pysiewicz

“…There are multiple mechanisms underlying this complication in IBD: e.g. malnutrition, disrupted gut microbiota, pharmacotherapy, and elevated inflammatory cytokines. Nevertheless, there are some possible interventions that can be undertaken to counteract this complication. …”
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Huoxiang Zhengqi dropping pills alleviate exertional heat stroke–induced multiple organ injury through sustaining intestinal homeostasis via regulating MAPK/NF-κB pathway and gut m... by Lei Li, Lei Li, Lei Li, Jun Ma, Jun Ma, Zeshi Li, Zeshi Li, Juelin Chen, Jiawei Zhou, Yawei Wang, Yankun Pei, Yitong Gong, Jianyao You, Yangyang Cao, Man Wang, Jikuai Chen, Wenjun Chang, Weiyi Ma, Hanyu Zhu, Chuhan Xiang, Shuogui Xu, Qing Song, Qing Song

“…The findings revealed that high-dose HXZQD significantly delayed the onset of EHS, reduced core body temperature elevations, and mitigated multi-organ injury, as evidenced by biochemical markers and histopathological examination. …”
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Axenfeld-Rieger Syndrome Associated with Congenital Glaucoma and Cytochrome P4501B1 Gene Mutations by Mukesh Tanwar, Tanuj Dada, Rima Dada

“…Clinical manifestations of this patient include bilateral elevated intraocular pressure (>40 mmHg) with increased corneal diameter (>14 mm) and corneal opacity. …”
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Circulating miRNA-125b Is a Potential Biomarker Predicting Response to Rituximab in Rheumatoid Arthritis by Isabelle Duroux-Richard, Yves-Marie Pers, Sylvie Fabre, Meryem Ammari, Dominique Baeten, Guillaume Cartron, Isabelle Touitou, Christian Jorgensen, Florence Apparailly

“…Detectable levels of miR-125b were measured in total blood and serum samples and were significantly elevated in RA patients compared to osteoarthritic and healthy donors. …”
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Two Novel Mutations Identified in an African-American Child with Chediak-Higashi Syndrome by Kerry Morrone, Yanhua Wang, Marjan Huizing, Elie Sutton, James G. White, William A. Gahl, Karen Moody

“…Her laboratory evaluation was remarkable for pancytopenia, high serum ferritin and an elevated LDH. Bone marrow aspirate revealed large inclusions in granulocytes and erythrophagocytosis consistent with HLH. …”
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Mixed Large Cell Neuroendocrine Carcinoma and Adenocarcinoma with Spindle Cell and Clear Cell Features in the Extrahepatic Bile Duct by John Wysocki, Rishi Agarwal, Laura Bratton, Jeremy Nguyen, Mandy Crause Weidenhaft, Nathan Shores, Hillary Z. Kimbrell

“…CA19-9 and alpha-fetoprotein (AFP) were elevated. Cholangioscopy revealed a friable mass extending from the middle of the common bile duct to the common hepatic duct. …”
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Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients by Ghaith Hamza Kamil, Mohammed Mezher Hussein, Raya Ezzat Maroof

“… Chronic kidney disease (CKD) is a growing international health concern with elevating mortality rate in the world today and it is generally a progressive and irreversible issue. …”
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