Enhanced Recovery of Bioactive Compound from Pineapple Peel Using Ultrasonic-Assisted Extraction with Enzyme Treatment at Varying Extraction Time by Amalia Nur Kumalaningrum, Zulmilafatma Nurlita Arini, Jefri Pandu Hidayat

“…The addition of Cellulase elevated the yield, phenolic, and flavonoid content. …”
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The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome by Lan Luo, Xiaoli Zhuang, Lin Fu, Ziyuan Dong, Shuyuan Yi, Kan Wang, Yu Jiang, Ju Zhao, Xiaofang Yang, Feilong Hei

“…Abstract Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a severe respiratory condition associated with elevated morbidity and mortality. Understanding their complex pathophysiological mechanisms is crucial for developing new preventive and therapeutic strategies. …”
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Genetic Instability Promotes the Acquisition of Chromosomal Imbalances in T1b and T1c Breast Adenocarcinomas by Harald Blegen, B. Michael Ghadimi, Annukka Jauho, Anders Zetterberg, Elina Eriksson, Gert Auer, Thomas Ried

“…Amplification events correlated with elevated cyclin A and reduced p27 expression, respectively. …”
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Circulating Oxidized Low-Density Lipoproteins and Antibodies against Oxidized Low-Density Lipoproteins as Potential Biomarkers of Colorectal Cancer by Dorota Diakowska, Krzysztof Grabowski, Mirosław Nienartowicz, Paweł Zarębski, Kamila Fudalej, Krystyna Markocka-Mączka

“…Serum CEA levels were significantly elevated in the advanced stage of disease, primary tumor progression, angiolymphatic invasion, and presence of distant metastasis. …”
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Parathyroid carcinoma and pheochromocytoma in a patient with neurofibromatosis type 1: a rare association by Jardelina Brena Rocha Leite, Nicole Ramalho De Freitas, Rafaella Nelice de Holanda Cardoso, Erik Trovão Diniz, Gabriel Rodrigues de Assis Ferreira, Fernão Henrique Costa e Alvim, Camila Ribeiro Coutinho Madruga, Ana Carolina Thé Garrido, Luciano Albuquerque, Patricia Sampaio Gadelha, Ruy Lyra, Lucio Vilar

“…The case report outlines a 33-year-old woman with neurofibromatosis type 1 (NF1) presenting complex symptomatology including a cervical mass, bone pain and significantly elevated calcium and parathyroid hormone levels, indicative of parathyroid carcinoma accompanied by cystic fibrous osteitis. …”
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Case report: Hypoparathyroidism-sensorineural hearing loss-renal dysplasia without febrile seizures: a novel mutation in the GATA3 gene by Haibin Chen, Haibin Chen, Yudi Zhang, Xueyao Yang, Xueyao Yang, Yongzhen Li

“…Laboratory tests revealed decreased serum calcium, elevated blood phosphorus levels, and reduced parathyroid hormone (PTH) levels, indicating the presence of “Hypoparathyroidism”. …”
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Retroperitoneal Extraovarian Fibrothecoma Mimicking a Malignant Epithelial Ovarian Carcinoma by Patrick Roberts, Sharon Nofech-Mozes, Natalie Coburn, Paul Hamilton, Lilian T. Gien

“…We describe a 62-year-old woman with history, physical examination, and imaging suggestive of metastatic ovarian cancer. CA-125 was elevated at 1291 U/mL. Paracenteses were negative for malignant cells and core biopsy showed spindle cell proliferation. …”
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Melatonin Promotes Yield Increase in Wheat by Regulating Its Antioxidant System and Growth Under Drought Stress by Xue Li, Jia Liu, Cuiping Zhang, Ze Liu, Xiang Guo, Shaoxiang Li, Hongsheng Li, Kun Liu, Kunzhi Li, Mingliang Ding

“…Then, 100 µM melatonin seed coating elevated the activity of antioxidant enzymes (CAT, Cu/Zn-SOD, POD, and T-GSH) in wheat seedlings and strengthened the resistance of wheat to drought stress. …”
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Correlation between Oxidative Stress and Thyroid Function in Patients with Nephrotic Syndrome by Sangita U. Sawant, Subhash Chandran, Alan F. Almeida, M. G. R. Rajan

“…Estimation of lipid peroxidation (LPx) catalase, superoxide dismutase (SOD), and Glutathione peroxidase (GPx) were carried out by standard methods. Results. TSH was elevated in the nephrotic patients compared to controls, while TT4 and TT3 were significantly lower in the patients than in controls. …”
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Dengue Virus Infection Causes the Activation of Distinct NF-κB Pathways for Inducible Nitric Oxide Synthase and TNF-α Expression in RAW264.7 Cells by Yi-Lin Cheng, Yee-Shin Lin, Chia-Ling Chen, Shu-Wen Wan, Yi-Dan Ou, Chia-Yi Yu, Tsung-Ting Tsai, Po-Chun Tseng, Chiou-Feng Lin

“…In addition to TNF-α production in DENV-infected murine macrophage RAW264.7 cells, inducible NO synthase was transcriptionally and posttranslationally elevated and accompanied by NO generation. NF-κB is known to be activated by DENV infection. …”
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Resolving Moving Heliospheric Structures Using Interplanetary Scintillation Observations With the Murchison Widefield Array by A. Waszewski, J. S. Morgan, R. Chhetri, R. Ekers, M. C. M. Cheung, N. D. R. Bhat, M. Johnston‐Hollitt

“…In spite of these observations being taken at sunspot minimum, this search has revealed several interesting transitory features characterized by elevated scintillation levels. One solar wind enhancement is captured in two observations several hours apart, allowing its radial movement away from the Sun to be measured. …”
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Building Credibility with Comprehensive Citation Practices by Pavithra Subramanian, Raghuraman Soundararajan, Jyotsna Makol

“…The goal of this article is to elevate the quality and credibility of academic publications in the area of medicine by focusing on the principles and methods of effective citation.…”
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Bioinformatics approaches to multi-omics analysis of the potential of CDKN2A as a biomarker and therapeutic target for uterine corpus endometrial carcinoma by Liang Ma, Yuling Li, Jingxian Wu, Yanfei Gao

“…CDKN2A expression was found to be elevated in UCEC, particularly in the signaling pathways involved in cell proliferation and inflammation. …”
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Subgroups based on fears of evaluation exhibited different social anxiety levels by Yifei Zhang, Junwen Chen, Haiping Liao, Limei Zhou, Hua Zhang, Yunglung Tang, Aiyue Huang, Ofir Turel, Yin Wu, Qinghua He

“…Abstract The bivalent fear of evaluation model proposes that fear of negative evaluation (FNE) and fear of positive evaluation (FPE) are distinct but related constructs, and that social anxiety arises when they are elevated. This represents a variable-centered perspective. …”
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Uncoupling Protein 2 Increases Susceptibility to Lipopolysaccharide-Induced Acute Lung Injury in Mice by Qin Wang, Jianchun Wang, Mingdong Hu, Yu Yang, Liang Guo, Jing Xu, Chuanjiang Lei, Yan Jiao, JianCheng Xu

“…Additionally, mitogen-activated protein kinases (MAPKs) activity was elevated, which increased the sensitivity to LPS-induced apoptosis and inflammation. …”
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Unlocking Consumer Preferences: Sensory Descriptors Driving Greek Yogurt Acceptance and Innovation by Helena Maria Andre Bolini, Flavio Cardello, Alessandra Cazellatto de Medeiros, Howard Moskowitz

“…The contemporary emphasis on health and wellness has elevated Greek yogurt as a functional food, recognized for its high protein content and bioavailable probiotics that support overall health. …”
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Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in Mice by Takefumi Kimura, Takero Nakajima, Yuji Kamijo, Naoki Tanaka, Lixuan Wang, Atsushi Hara, Eiko Sugiyama, Eiji Tanaka, Frank J. Gonzalez, Toshifumi Aoyama

“…Furthermore, increases in CST mRNA levels were correlated with mRNA elevations of several known PPARα target genes, and such changes were not observed for other sulfatide-metabolism enzymes in the liver. …”
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Protective effects of Bifidobacterium breve on imiquimod-induced psoriasis in mice through secondary bile acid production and FXR-TLR4/NF-κB pathway by Xinqi Chen, Yang Chen, Catherine Stanton, R.Paul Ross, Jianxin Zhao, Bo Yang, Wei Chen

“…B. breve CCFM683 significantly ameliorated psoriasis in mice as well as elevated the deoxycholic acid (DCA) and lithocholic acid (LCA) in the colon compared with those of the imiquimod (IMQ)-treated mice. …”
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Clinical impacts of Artocarpus lakoocha agglutinin-binding glycans for prognosis and treatment of cholangiocarcinoma by Phisit Sintusen, Kulthida Vaeteewoottacharn, Ubon Cha’on, Chawalit Pairojkul, Chaiwat Aphivatanasiri, Sutas Suttiprapa, Panupong Mahalapbutr, Atit Silsirivanit, Sopit Wongkham, Sukanya Luang

“…ALA-histochemistry was used to evaluate ALAG expression in liver fluke-induced CCA tissues from hamsters (n = 60). Elevated ALAG expression was observed in hyperplastic ducts and significantly increased in CCA tissues, while normal biliary epithelium and hepatocytes showed no expression. …”
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IL-1β Suppresses the Formation of Osteoclasts by Increasing OPG Production via an Autocrine Mechanism Involving Celecoxib-Related Prostaglandins in Chondrocytes by Yusuke Watanabe, Aki Namba, Yukiko Aida, Kazuhiro Honda, Hideki Tanaka, Naoto Suzuki, Hideo Matsumura, Masao Maeno

“…Elevated interleukin (IL)-1 concentrations in synovial fluid have been implicated in joint bone and cartilage destruction. …”
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