Maternal Weight Gain in Pregnancy and Risk of Obesity among Offspring: A Systematic Review by Erica Y. Lau, Junxiu Liu, Edward Archer, Samantha M. McDonald, Jihong Liu

“…Evidence from cohort studies supports that total GWG and exceeding the Institute of Medicine maternal weight gain recommendation were associated with higher BMI z-score and elevated risk of overweight or obesity in offspring. …”
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The Correlation of PPARα Activity and Cardiomyocyte Metabolism and Structure in Idiopathic Dilated Cardiomyopathy during Heart Failure Progression by E. Czarnowska, D. Domal-Kwiatkowska, E. Reichman-Warmusz, J. B. Bierla, A. Sowinska, A. Ratajska, K. Goral-Radziszewska, R. Wojnicz

“…In conclusion, PPARα elevated levels may be a direct cause of adverse remodeling, both metabolic and structural. …”
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Birthing parent adverse childhood experiences and risk of atopic diseases in 5-year-old children by Makayla Freeman, Makayla Freeman, Anna L. MacKinnon, Anna L. MacKinnon, Mark Anselmo, Mark Anselmo, Suzanne Tough, Suzanne Tough, Suzanne Tough, Lianne Tomfohr-Madsen

“…Birthing parent history of ACEs, combined with birthing parent history of atopy, may elevate the risk of child atopy. This presents an opportunity for early intervention for children at risk of atopic disease.…”
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Hepatic Cholesterol-25-Hydroxylase Overexpression Improves Systemic Insulin Sensitivity in Mice by Britta Noebauer, Alexander Jais, Jelena Todoric, Klaus Gossens, Hedwig Sutterlüty-Fall, Elisa Einwallner

“…Oxysterols are naturally occurring molecules that play important role in various metabolic and inflammatory processes and their levels are elevated in patients suffering from obesity and diabetes. 25-Hydroxycholesterol (25-OHC) is produced in cells from cholesterol by the enzyme cholesterol 25-hydroxylase (Ch25h) and is involved in lipid metabolism, inflammatory processes, and cell proliferation. …”
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Arginine methyltransferase PRMT1 promotes ferroptosis through EGR1/GLS2 axis in sepsis-related acute lung injury by Min Li, Longhui Hu, Qiao Ke, Zhao Li, Chujun Ruan, Hanjing Lu, Xiaoran Liu

“…Here we show, there were elevated ferroptosis and increased expression levels of protein arginine methyltransferase 1 (PRMT1), early growth response 1 (EGR1), and glutaminase 2 (GLS2) in both in vitro and in vivo ALI models. …”
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Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic Review by Rajaram Khanal, Shreeyash Raj Bhattarai, Kriti Basnet, Sangam Shah, Roman Dhital, Sanjit Kumar Sah, Sujan Poudel, Odalys Frontela, George Michel, Sima Marzban, Alfonso J. Rodriguez-Morales

“…Cardiac complications such as heart failure, myocardial injury, and arrhythmias are common among patients infected with COVID-19. Elevated cardiac markers and patients with cardiac complications require utmost care and continuous cardiac monitoring.…”
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Allergic Interstitial Nephritis Manifesting as a Striated Nephrogram by Irfan Moinuddin, Erika Bracamonte, Bijin Thajudeen, Amy Sussman, Machaiah Madhrira, James Costello

“…Guidelines suggest that AIN should be suspected in a patient who presents with an elevated serum creatinine and a urinalysis that shows white cells, white cell casts, or eosinophiluria. …”
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Role of Cathepsin S in Periodontal Inflammation and Infection by S. Memmert, A. Damanaki, A. V. B. Nogueira, S. Eick, M. Nokhbehsaim, A. K. Papadopoulou, A. Till, B. Rath, S. Jepsen, W. Götz, C. Piperi, E. K. Basdra, J. A. Cirelli, A. Jäger, J. Deschner

“…Both stimulants caused a significant cathepsin S upregulation. A significantly elevated cathepsin S expression in gingival biopsies from rats with experimental periodontitis was found in vivo, as compared to that from control. …”
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Male Central Precocious Puberty: Serum Profile of Anti-Müllerian Hormone and Inhibin B before, during, and after Treatment with GnRH Analogue by Romina P. Grinspon, Luz Andreone, Patricia Bedecarrás, María Gabriela Ropelato, Rodolfo A. Rey, Stella M. Campo, Ignacio Bergadá

“…At diagnosis, inhibin B was elevated and decreased throughout therapy, remaining in the upper normal prepubertal range. …”
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A Case of Idiopathic Acute Pancreatitis in the First Trimester of Pregnancy by Tomomi Hara, Haruhiko Kanasaki, Aki Oride, Tomoko Ishihara, Satoru Kyo

“…Blood investigations showed elevated level of C-reactive protein (9.58 mg/dL), pancreatic amylase (170 IU/L), and lipase (332 IU/L). …”
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Extracellular HMGB1 Induced Glomerular Endothelial Cell Injury via TLR4/MyD88 Signaling Pathway in Lupus Nephritis by Tian Yu, Feng Xiaojuan, Liu Jinxi, Miao Xinyan, Xu Jie, Tian Yuexin, Liu Qingjuan, Zhang Wei, Gu Cunyang, Huang Jie, Wu Lunbi, Zhao Hang, Liu Shuxia, Guo Huifang

“…Previously, our study showed that HMGB1 was significantly elevated in the blood and located in the glomerular endothelium in LN patients. …”
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Does the Admission Blood Pressure Associate with Short- and Long Term Outcome in Stroke Patients Treated with Thrombolysis? A Single Centre Study by L. Bentsen, C. Ovesen, A. F. Christensen, H. Christensen

“…The association between outcome and elevated admission blood pressure (BP) remains uncertain in acute stroke patients. …”
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Diisooctyl phthalate (DIOP) exposure leads to cell apoptosis to HUVEC cells and toxicity to Caenorhabditis elegans through increasing the oxidative stress by Siyuan Luo, Junnan Li, Yuqing Zhou, Zihang Zhai, Qiang Li, Zhenglin Huang, Wencan He, Kejun Zhong, Bo Kong, Zanxian Xia, Hang Fai Kwok, Lipeng Zhu

“…Moreover, this cytotoxicity correlates with elevated levels of reactive oxygen species (ROS), causing cell cycle arrest at the G1 phase and the induction of cell apoptosis. …”
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The Serum Level of Fibroblast Growth Factor-23 and Calcium-Phosphate Homeostasis in Obese Perimenopausal Women by M. Holecki, J. Chudek, A. Więcek, M. Titz-Bober, J. Duława

“…No correlation between serum phosphorus or eGFR and plasma iFGF-23 and between eGFR and serum phosphorus was found. Elevated serum iFGF-23 concentration may partially explain lower phosphorus levels in the obese and seems not to reflect bone turnover.…”
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HIFU-CCL19/21 Axis Enhances Dendritic Cell Vaccine Efficacy in the Tumor Microenvironment by Bum-Seo Baek, Hyunmi Park, Ji-Woong Choi, Eun-Young Lee, Seung-Yong Seong

“…Results: The combination of M-HIFU and DC vaccine significantly inhibited tumor growth and metastasis, with enhanced T-cell activation and increased recruitment of immune cells due to elevated chemokines CCL19 and CCL21. This synergy promoted immune memory, reducing the likelihood of recurrence. …”
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Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain by Cui Yan Lu, De Xiang Liu, Hong Jiang, Fang Pan, Cyrus S. H. Ho, Roger C. M. Ho

“…This study used inescapable foot-shock to induce PTSD in juvenile rats and examined their emotional changes using open-field test and elevated plus maze, memory changes using Morris water maze, and the expression of GABAAR subunits (γ2, α2, and α5) in subregions of the brain in the adulthood using western blotting and immunohistochemistry. …”
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Mitochondrial DNA variants and their impact on epigenetic and biological aging in young adulthood by Klara Mareckova, Ana Paula Mendes-Silva, Martin Jáni, Anna Pacinkova, Pavel Piler, Vanessa F. Gonçalves, Yuliya S. Nikolova

“…These findings suggest that elevated FI score of mtDNA variants might contribute to premature aging in young adulthood.…”
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Suspected Nonalcoholic Fatty Liver Disease Is Not Associated with Vitamin D Status in Adolescents after Adjustment for Obesity by Karin Katz, Preneet Cheema Brar, Niyati Parekh, Ying-Hua Liu, Michael Weitzman

“…In analyses utilizing vitamin D as a continuous variable, no independent association was found between Vitamin D levels and rates of elevated ALT levels. In multivariate analyses, higher risks for suspected NAFLD were observed in males and overweight adolescents; however, vitamin D status was not found to be independently associated with suspected NAFLD after adjusting for obesity.…”
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Giant Photoluminescence Enhancement of Ga‐Doped ZnO Microwires by X‐Ray Irradiation by Siyuan He, Shuiyan Cao, Ying Liu, Wenfa Chen, Pin Lyu, Weidian Li, Jincheng Bao, Wenhui Sun, Caixia Kan, Mingming Jiang, Yanpeng Liu

“…In addition, the X‐ray irradiated microwires further exhibit elevated electroluminescence by over three times. The enhanced photoluminescence and electroluminescence as well as long‐term stability enable us to imagine the super‐rapid applications of ZnO microwires in modern optoelectronic devices.…”
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Antibody Responses and the Vaccine Efficacy of Recombinant Glycosyltransferase and Nicastrin Against <i>Schistosoma japonicum</i> by Bowen Dong, Haoran Zhong, Danlin Zhu, Luobin Wu, Jinming Wang, Hao Li, Yamei Jin

“…Immunized mice exhibited significantly elevated specific IgG antibody levels after three immunizations compared to adjuvant and PBS controls. …”
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