Critical updates on oral insulin drug delivery systems for type 2 diabetes mellitus by Chan Yew Low, Wei Ling Gan, Su Jeat Lai, Rachel Su-May Tam, Jie Fei Tan, Stefanie Dietl, Lay Hong Chuah, Nicolas Voelcker, Athirah Bakhtiar

“…Abstract Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by insulin resistance, leading to elevated blood sugar levels. Exogenous insulin can counteract the diminished response to insulin and effectively controlling blood glucose levels, thereby minimizing diabetes-related complications. …”
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Influence of the Injection Process on Two-Phase Separation in Stainless-Steel Metal Powder Injection Molding by Yan Li, Xingjie Peng, Xiang Zan, Laima Luo, Yucheng Wu

“…The simulation results indicate that the separation of binder and powder is most severe near the gate, where the binder percentage is the highest. The application of elevated mold temperatures, augmented injection rates and reduced injection temperatures can effectively mitigate the two-phase separation phenomenon and enhance the uniformity of powder distribution. …”
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Interactive and unimodal relationships between plant biomass, abiotic factors, and plant diversity in global grasslands by Marie Spohn, Sumanta Bagchi, Jonathan D. Bakker, Elizabeth T. Borer, Clinton Carbutt, Jane A. Catford, Christopher R. Dickman, Nico Eisenhauer, Anu Eskelinen, Nicole Hagenah, Yann Hautier, Sally E. Koerner, Kimberly J. Komatsu, Lauri Laanisto, Ylva Lekberg, Jason P. Martina, Holly Martinson, Meelis Pärtel, Pablo L. Peri, Anita C. Risch, Nicholas G. Smith, Carly Stevens, G. F. Ciska Veen, Risto Virtanen, Laura Yahdjian, Alyssa L. Young, Hillary S. Young, Eric W. Seabloom

“…Further, we found that soil nitrogen and plant diversity interacted in their relationships with plant biomass, such that plant diversity and biomass were positively related at low levels of nitrogen and negatively at elevated levels of nitrogen. Our results show that it is critical to account for the interactive and unimodal relationships between plant biomass and several environmental variables to accurately include plant biomass in global vegetation and carbon models.…”
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Clinical presentation and management challenges of sphingosine-1-phosphate lyase insufficiency syndrome associated with an SGPL1 variant: a case report by Vahid Saeedi, Nahid Rahimzadeh, Fahimeh Ehsanipour, Neda Shalbaf, Amirhosein Farahi, Khalil Rashidi, Leila Kamalzadeh

“…Laboratory evaluation revealed hypoalbuminemia, significant proteinuria, hyperkalemia, and elevated adrenocorticotropic hormone (ACTH) levels. …”
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Mineralogical and geochemical peculiarities and gold content of pyrite and arsenopyrite of the Southern Ashaly gold deposit (East Kazakhstan) by Greku E. D., Kalinin Yu. A., Serdyukov A. N., Naumov E. A., Borovikov A. A., Ragozin A. L., Gladkov A. S.

“…The following successive generations of pyrite were established at the deposit: diagenetic, metamorphic, and hydrothermal, that embrace six varieties with its own geochemical features. Elevated concentrations of gold in diagenetic pyrite have been recorded and visually confirmed. …”
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Follistatin like-1 aggravates silica-induced mouse lung injury by Yinshan Fang, Si Zhang, Xiaohe Li, Fangxin Jiang, Qiao Ye, Wen Ning

“…The mechanisms underlying the diseases are unknown, so that no effective treatment exists for these conditions. We found elevated levels of follistatin like 1 (FSTL1) in serum from patients with silicosis and in lungs from silica-induced mouse model. …”
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Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm by Soheila Aminimoghaddam, Narmin Karisani, Maryam Mazloomi, Maryam Rahimi

“…A 29-year-old woman with incomplete abortion was referred to an oncologist for possible GTN due to persistent active vaginal bleeding, an elevated beta human chorionic gonadotropin (hCG), abnormal cervical inspection exam, abnormal liver function tests, ovarian enlargement, ascites, and a pleural effusion. …”
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Immune Response of Mormon Crickets That Survived Infection by Beauveria bassiana by Robert B. Srygley, Stefan T. Jaronski

“…survivors' PO activity was elevated to the same level independent of dose. Those with fungal cells visible in their hemolymph did not differ in PO activity from those with clear hemolymph. …”
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Oxy-inflammation in hyperbaric oxygen therapy applications by Gerardo Bosco, Andrea Brizzolari, Matteo Paganini, Enrico Camporesi, Alessandra Vezzoli, Simona Mrakic-Sposta

“…HBOT relies on increasing the inspired O2 fraction (fiO2) and elevating the partial pressure of O2 (pO2). O2 is typically administered at pressures between 1.5 and 3.0 ATA for 60 to 120 minutes, depending on the clinical presentation. …”
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Assessing the Effect of Air Blast Loading on the Structural Behaviour of Reinforced Concrete Column. by Kasyage, Abubakali

“…Findings indicate that increased charge weights and reduced stand-off distances significantly elevate the risk of shear and flexural failures. The study underscores the importance of incorporating nonlinear material behavior in simulations to accurately predict structural responses. …”
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Análise multicriterial para avaliação da susceptibilidade à ocorrência de quedas de blocos na vertente noroeste da serra da Meruoca, Ceará, Brasil by Adisson Souza Tavares, Frederico de Holanda Bastos

“…From the results it was identified that most of the basin has a very low and low susceptibility level (46%), being these the lower portions close to the exutory already on the erosive surfaces surrounding the massif, in addition to the alveolar plains, with colluvium-alluvial deposit, located on the elevated surfaces of the mountain range. The most susceptible classes, on the other hand, make up about 1/3 of the area, being environments that are not favorable to human occupation, very influenced by the high declivities, preferably located on the massif slopes.…”
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Evaluating the challenges and opportunities for diabetes care policy in Nigeria by Olatunde Olalekan Isaac

“…Diabetes mellitus is a metabolic, non-communicable disease characterized by elevated blood glucose levels resulting from defects in insulin function, secretion, or both. …”
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Coexistence between people and polar bears supports Indigenous knowledge mobilization in wildlife management and research by Katharina M. Miller, Georgina Berg, Indigenous Knowledge Keepers of Churchill, Michael Lickers, Nickia McIvor, Dominique A. Henri

“…Through this case study, we explored human-polar bear coexistence in the community through Indigenous voices, documented social-ecological change, and mobilized recommendations as future visions to inform inclusive management and research strategies: elevate Indigenous knowledge, support proactive management and less invasive research, cultivate a culture of coexistence, improve education and safety awareness, and protect polar bears to support tourism. …”
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Joint Waterstop Design for 250 m Ultra-high Concrete Face Rockfill Dams in Cold and Seismically Active Regions by YIN Ming, CHEN Xing, XIONG Kun

“…These challenges necessitate an elevated standard for waterstop design. Using the 233.5 m high Yulongkashi CFRD as a case study, this paper quantitatively proposes a joint deformation control standard based on the results of 3D static and dynamic finite element analysis, in conjunction with relevant engineering experiences. …”
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The politics of environmental policy: haze pollution, ASEAN, and the way forward by Bama Andika Putra, Bama Andika Putra

“…It is recommended that an ASEAN code of conduct be introduced to elevate the importance of transboundary haze regulations in Southeast Asia. …”
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Mediastinal Extension of a Pancreatic Pseudocyst: A Rare Intrathoracic Complication of Pancreatitis by Carol Vitellas, Ivo Besong Mangeb, Luis Regalado, Chiemezie Chianotu Amadi

“…We present a case of mediastinal extension of a pancreatic pseudocyst in a 56-year-old woman with a history of alcohol-related chronic pancreatitis, who presented with acute on chronic epigastric abdominal pain and atypical chest pain. Serum lipase was elevated, and imaging by contrast-enhanced computed tomography (CT) demonstrated a paraesophageal fluid collection. …”
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L’enceinte urbaine d’Aurillac (Cantal) : état des connaissances sur ses origines et son évolution by Marie Caillet

“…In 2019, a preventive archeological excavation in the Frères Charmes block, on a south-east portion of the urban enclosure of Aurillac, made it possible to study the curtain wall elevations, and to gather information on the area through a sedimentary survey. …”
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Post-Processing Thermal Activation of Thermoelectric Materials Based on Germanium by Piotr Marek Markowski, Eugeniusz Prociów

“…The first method was to place the structure at an elevated temperature for a specified period of time. …”
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COMPETENȚA CA MODEL DE RELAȚIONARE by USM ADMIN

“…Articolul își propune să extragă din câteva modele de învățare elemente care susțin că oricât de bine organizate vor fi mecanismele predării și de înnoită este tehnologia, permanentă și inseparabilă va fi relațioarea profesor-elev. Perspectiva este susținută de recente preocupări mai ample consacrate relaționării didactice și de un recent model generat de analiza trangenerațională a acesteia în care tehnologia este prezentă prin conținutul său informațional reflectat de TPACK supus condiționărilor alternativei pedagogice Reggio Emilia. …”
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Genetic Cholestasis: Lessons from the Molecular Physiology of Bile Formation by Peter LM Jansen, Michael Müller

“…PFIC types 1 and 2 are characterized by cholestasis and a low to normal serum gamma-glutamyltransferase (GGT) activity, whereas in PFIC type 3, the serum GGT activity is elevated. PFIC types 1 and 2 occur due to mutations in loci at chromosome 18 and chromosome 2, respectively. …”
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