A Severe Case of Drug-Induced Liver Injury after Gemcitabine Administration: A Highly Probable Causality Grading as Assessed by the Updated RUCAM Diagnostic Scoring System by Ilenia Mascherona, Caterina Maggioli, Maira Biggiogero, Oreste Mora, Lucia Marelli

“…Transient serum enzyme elevations could be observed during therapy, but clinically significant acute liver injury has been rarely associated with its use. …”
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The role of myocardial energy metabolism perturbations in diabetic cardiomyopathy: from the perspective of novel protein post-translational modifications by Dongze Li, Li Zhang, Qiming Gong, Huilan Deng, Changfang Luo, Tingting Zhou, Wei Huang, Yong Xu

“…Abstract Diabetic cardiomyopathy (DbCM), a significant chronic complication of diabetes, manifests as myocardial hypertrophy, fibrosis, and other pathological alterations that substantially impact cardiac function and elevate the risk of cardiovascular diseases and patient mortality. …”
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Research Progress in Lactoferrin’s Role in Alleviating Intestinal Barrier Dysfunction by LI Yi, REN Xinxin, WANG Qin, HE Xiaoyun

“…Numerous studies have shown that lactoferrin elevates the levels of intestinal tight junction proteins, promotes the growth and development of intestinal cells, down-regulates the expression of inflammatory factors, regulates the immune response and intestinal microbial diversity, and contributes to the maintenance of intestinal barrier homeostasis. …”
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TYPOCHEMISTRY OF MAGNETITE FROM MASSIVE SULFIDE AND IRON DEPOSITS OF THE URALS ACCORDING TO LA-ISP-MS DATA by V.V. Maslennikov, N.R. Ayupova, A.S. Tseluyko, N.P. Safina, D.A. Artemyev, U.A. Yatimov, S.I. Bryukhov, P.V. Khvorov, M.A. Rassomakhin

“…It is established using laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS) that, in contrast to magnetite of iron deposits, magnetite of ore-controlling volcanosedimentary horizons of the Urals massive sulfide deposits is characterized by a higher content and stable associations of Bi, Te, Co, As, Cd, Zn, Cu and Mo due to relict inclusions of sulfide clasts and products of their halmyrolysis. The elevated Ti, V and Zr contents, as well as the mixed associations of lithophile, siderophile and chalcophile elements, are more typical of magnetite of iron deposits after hyaloclastites. …”
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First evidence of sinter and travertine in Cameroon: fault reactivation and geothermal implications by Tchouatcha, Milan Stafford, Kouske, Arnaud Patrice, Tamfuh, Primus Azinwi, Préat, Alain, Toyama, René, Feumba, Roger, Tiokeng Ngounfack, Vannelle, Madjingain, Vivant, Konglim, Yaya Berinyuy, Tchameni, Rigobert

“…$\delta ^{13}\mathrm{C}$ and ${\delta }^{18}\mathrm{O}$ values, ranging respectively from 1.5‰ to 2.9‰ V-PDB and ${-}$10.1‰ to ${-}$6‰ V-PDB, reflect a high temperature of the parent solution (40 °C) related to an elevated geothermal gradient. The europium anomalies values (Eu/Eu*: 0.54–1.78) indicate the temperature variation of precipitated deposits related to distance of the deep hot water flow. …”
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Circulating Endothelial Microparticles in Diabetes Mellitus by A. F. Tramontano, R. Lyubarova, J. Tsiakos, T. Palaia, J. R. DeLeon, L. Ragolia

“…Circulating CD31+, CD105+, and CD106+ EMPs were significantly elevated in patients with DM. EMPs were the only independent predictors of DM in our study cohort. …”
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Serum creatine-kinase and extended breastfeeding: Case study by Ksenija Bubnjević, Bojana Marić, Dušan Stupar, Dragan Grujičić

“…After the competition, elevated serum creatine-kinase levels were noted. Prolactin and TSH values remained within optimal values. …”
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Microstructure and mechanical property degradation mechanism of Cu–Cr–Zr rail after extreme electromagnetic launches by Chengcheng Li, Weihao Li, Shiyu Hao, Huantong Shi, Li Chen, Chuncai Kong, Feng Jiang, Xingwen Li

“…Theoretical analysis proves the dominant role of the elevated temperature and the thermal phonon-dislocation interactions in reducing the dislocation activation energy and density, which lowers the diffusion coefficient and refines the precipitate by dissolution and re-precipitation induced by the extreme conditions. …”
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Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Rhodiola crenulate in DSS-induced colitis through plasma pharmacochemistry and metabolomics by Yu Peng, Xiaoao Xiao, Tingting Ji, Xinyuan Wang, Yixuan Xu, Jianbo Xiao, Hui Cao, Zhiyong Chen, Huifan Liu, Yuanqing Gao, Hongxun Tao

“…The decreased flavonoids prototype and the elevated sulfated products of phenols were observed under pathophysiological conditions of colitis. …”
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Knockout or inhibition of DHPS suppresses ovarian tumor growth and metastasis by attenuating the TGFβ pathway by Guannan Zhao, Xinxin Zhao, Ziping Liu, Baojin Wang, Peixin Dong, Hidemichi Watari, Lawrence M. Pfeffer, Gabor Tigyi, Wenjing Zhang, Junming Yue

“…In this study, we show that DHPS is amplified in OC patients, and its elevated expression correlates with poor survival. …”
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Adult ADHD Medications and Their Cardiovascular Implications by A. Sinha, O. Lewis, R. Kumar, S. L. H. Yeruva, B. H. Curry

“…Cardiovascular response attributed to ADHD medication has mainly been observed in heart rate and blood pressure elevations, while less is known about the etiology of rare cardiovascular events like acute myocardial infarction (AMI), arrhythmia, and cardiomyopathy and its long-term sequelae. …”
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Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis by Beatriz Cicuéndez, Alfonso Mora, Juan Antonio López, Andrea Curtabbi, Javier Pérez-García, Begoña Porteiro, Daniel Jimenez-Blasco, Pedro Latorre-Muro, Paula Vo, Madison Jerome, Beatriz Gómez-Santos, Rafael Romero-Becerra, Magdalena Leiva, Elena Rodríguez, Marta León, Luis Leiva-Vega, Noemi Gómez-Lado, Jorge L. Torres, Lourdes Hernández-Cosido, Pablo Aguiar, Miguel Marcos, Martin Jastroch, Andreas Daiber, Patricia Aspichueta, Juan Pedro Bolaños, Jessica B. Spinelli, Pere Puigserver, José Antonio Enriquez, Jesús Vázquez, Cintia Folgueira, Guadalupe Sabio

“…MCJKO mice, even without UCP1, a fundamental thermogenic protein, exhibit elevated BAT thermogenesis. Electron microscopy unveils changes in mitochondrial morphology resembling BAT activation. …”
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RETRACTED: Dynamics of MHD Convection of Walters B Viscoelastic Fluid through an Accelerating Permeable Surface Using the Soret–Dufour Mechanism by P. Anusha, M. Naga Swapna Sri, Vallabhaneni Venkata Venu Madhav, Ch. Sri Chaitanya, V.V. Spandana, Kuldeep K. Saxena, Dalael Saad Abdul-Zahra, Emanoil Linul, Chander Prakash, Dharam Buddhi, Raul Campilho

“…The imposed magnetism was found to lessen the velocity plot while the thermal radiation term elevates the temperature plot because of the warm particles of the fluid.…”
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Radixin Enhances Colon Cancer Cell Invasion by Increasing MMP-7 Production via Rac1-ERK Pathway by Qi-Hong Jiang, Ai-Xiang Wang, Yan Chen

“…Interestingly, we found that the expression of radixin was significantly elevated in colon cancer cells. Knockdown of radixin suppressed the invasion and migration of colon cancer cells. …”
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Lessons Learned and Questions Raised by an Atypical Case of Clozapine-Induced Myocarditis by Charles H. Earnshaw, Lucy Powell, Owen Haeney

“…A diagnosis of myocarditis was confirmed as a result of elevated cardiac enzyme levels and an echocardiogram. …”
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Management of Recurrent Lung Infections in a Case of Hyperimmunoglobulinemia E (or Job’s) Syndrome by M Arsenault, V Echave, C Fish, J-P Praud

“…The diagnosis of hyperimmunoglobulinemia E (hyper IgE) or Job’s syndrome was made in a five-month-old girl with chronic staphylococcal mastitis, elevated serum IgE and abnormal neutrophil chemotaxis. …”
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Carcinogenic and Genotoxicity of some PAHs in commonly consumed smoked fish (<i>Parachanna obscura</i> and <i>Ethmalosa fimbriata) </i> by N.O. Erhunmwunse, S.A. Ekaye

“…Levels of PAHs present in smoked fish prepared using traditional method may pose elevated cancer risks if consumed at high rates over many years. …”
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Porphyric encephalopathy in a 15-year-old girl: A case report by Saihari S Dukkipati, Jordan Terschluse, Drew Thodeson, Angela Beavers, Melissa Muff-Luett, Claire Ives, Sookyong Koh

“…Her urine porphobilinogen level was markedly elevated, consistent with the diagnosis of acute intermittent porphyria. …”
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Ontology-Driven Mixture-of-Domain Documentation: A Backbone Approach Enabling Question Answering for Additive Construction by Chao Li, Frank Petzold

“…Additionally, a prototypical documentation tool is developed to elevate recorded information and BIM models as a knowledge graph. …”
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Serum calprotectin in nonsegmental vitiligo: a possible marker of disease activity by Dalia A. Bassiouny, Yasmin B. El Zawahry, Ahmed M. Soliman, Alaa H. Sayed, Eman R. Youness, Dina G. Saadi

“…Results Although the serum CP levels were not significantly higher in patients (median = 33.6) in comparison with controls (median = 33.5) (P=0.28), CP was significantly elevated in active vitiligo cases when compared with stable patients (P=0.010) and had a positive correlation with vitiligo disease activity score (r=0.400, P=0.009). …”
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