Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…Single-cell RNA-seq analysis further revealed that SLC11A1 expression was significantly elevated in the pro-inflammatory (M1-type) microglia and peripheral blood monocytes in AD. …”
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HMGB1 lactylation drives neutrophil extracellular trap formation in lactate-induced acute kidney injury by Li Zhu, Li Zhu, Qiang Zheng, Xiaodong Liu, Xiaodong Liu, Hao Ding, Mengqing Ma, Jiaxin Bao, Yawen Cai, Changchun Cao

“…We observed that co-administration of lactate with low-dose lipopolysaccharide (LPS) resulted in lactate overproduction, which subsequently elevated serum levels of creatinine (Cre) and blood urea nitrogen (BUN). …”
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Linear association between high-sensitivity C-reactive protein and postoperative delirium after general anesthesia: a cross-sectional study by Xiao Qin, Junming Ren, Chunping Xing, Lijiao Chen, Renjie Wang, Shouyuan Tian

“…Multivariate logistic regression confirmed that elevated Hs-CRP and its forms (Log10Hs-CRP, standardized Hs-CRP, and higher Hs-CRP group) consistently increased the risk of POD across all adjusted models (p < 0.05). …”
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Study on the value of gastrin 17 and aldehyde dehydrogenase 1 in gastric juice for early diagnosis in gastric cancer by Yanfang Wang, Yanfang Wang, Hui Liu, Hui Liu, Xiang Li, Juan Jin, Bo Yan, Bo Yan

“…The development of gastric cancer was significantly influenced by elevated levels of ALDH1 and G-17 in gastric juice (OR= 1.095, 1.018; both P <0.05); the AUCs for the combined diagnosis of gastric cancer and elevated levels of G-17 and ALDH1 in gastric juice were 0.792, 0.757, and 0.695, respectively.ConclusionThe development of gastric cancer is influenced by increased levels of ALDH1 and G-17 in gastric juice. …”
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The Effects of Anthropogenic Heat Release on Urban Meteorology and Implication for Haze Pollution in the Beijing-Tianjin-Hebei Region by Ruiting Liu, Zhiwei Han

“…This study revealed that AHR from cities exerted a significant impact on meteorology by generally increasing surface air temperature and wind speed, decreasing relative humidity, and elevating PBL height and near surface turbulent kinetic energy (TKE), which could consequently reduce surface pollutant concentration and mitigate haze pollution by enhancing atmospheric instability and turbulent mixing and reducing aerosol hygroscopic growth.…”
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Iron Deficiency Anemia in Adult Onset Still's Disease with a Serum Ferritin of 26,387 μg/L by Sheetal Patel, Seyed Monemian, Ayesha Khalid, Harvey Dosik

“…The coexistence of iron deficiency should be considered when evaluating a patient with anemia of chronic inflammation even when the ferritin level is elevated several hundredfold. Further insights on ferritin metabolism in Still's disease are suggested by the likelihood that the patient's massive hyperferritinemia in the acute phase of Still's disease was almost entirely of the iron-free apoferritin form.…”
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Propofol Suppresses Proinflammatory Cytokine Production by Increasing ABCA1 Expression via Mediation by the Long Noncoding RNA LOC286367 by Xin Ma, Teng Wang, Zhen-Long Zhao, Yu Jiang, Shu Ye

“…Western blot analysis showed that ABCA1 expression was elevated in macrophages by propofol treatment and this effect was markedly reduced by LOC286367 overexpression. …”
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Heat Stroke: A Medical Emergency Appearing in New Regions by Sofie Søndergaard Mørch, Johnny Dohn Holmgren Andersen, Morten Heiberg Bestle

“…Heat stroke is an acute, life-threatening emergency characterized clinically by elevated body temperature and central nervous system dysfunction. …”
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Overview of Depression Level in Knee Osteoarthritis Patients in Geriatric Polyclinic in General Hospital by Rakha Ariq Fadilah, Arief Yanto, Mohammad Fatkhul Mubin, Desi Ariyana Rahayu

“…Knee osteoarthritis (OA) is one of the most prevalent degenerative conditions among the elderly, significantly impacting both mental and physical health, including an elevated risk of depression. This study aims to assess the prevalence of depression distribution among patients with knee osteoarthritis attending the geriatric polyclinic at a Regional General Hospital in Indonesia. …”
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Phosphomolybdic acid boosts polyunsaturated fatty acid and neutral lipid production in Phaeodactylum tricornutum by Kun-Tao Peng, Bing-Hong Xiong, Gao Cheng, Gao Cheng, Yuan-Hong Zhong, Yuan-Hong Zhong, Lin Yu, Lin Yu

“…Phaeodactylum tricornutum is considered a potential lipid production platform due to its high growth rates and elevated natural neutral lipid and polyunsaturated fatty acid (PUFA) contents. …”
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Early Hepatic Dysfunction in a Large Animal Model of Nonhypotensive Sepsis by Stephen Sullivan, Michael Troster, Adam Linton

“…These data revealed that marked elevations in AST were associated with a higher central venous pressure and worse renal impairment, but there was no relationship with any other hemodynamic parameter, PO2, pH or serum lactate. …”
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Cognitive Biases in the Era of COVID-19 : A Case of Clostridium sporogenes Bacteremia in a Patient with Small Bowel Obstruction by Marc J. Vecchio, Matthew Jankowich, Hassan Qadir, Melissa Gaitanis, Anupama Menon

“…Upon review, bacteremia from Clostridium sporogenes was associated with high mortality rates and could produce similar elevations in the inflammatory markers observed in COVID-19 pneumonia. …”
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The Process‐Oriented Understanding on the Reduced Double‐ITCZ Bias in the High‐Resolution CESM1 by Enze Dong, Fengfei Song, Lixin Wu, Lu Dong, Shengpeng Wang, Fukai Liu, Hong Wang

“…The better representation of terrain, such as Andes Mountains, elevates warm advection from inland to the coastal region, which maintains the inversion structure favorable for low cloud. …”
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Diagnosis and Treatment of Sepsis in a Fourteen-year-old Patient: A case study of pulmonary inflammatory discharge without typical features of respiratory tract infection by Bartłomiej Żaczek, Jakub Kozłowski, Alicja Kamińska, Wojciech Kupczak, Kinga Bujak, Aleksandra Kocjan, Ismael Alsoubie, Natalie Papachristoforou, Wojciech Kaźmierski, Mateusz Ziomek, Paulina Lis, Marta Czubaj-Kowal

“…It is also important to consider the possibility of pulmonary congestion in case of postural pain and elevated levels of D-dimers. Regular patient monitoring and controlled laboratory studies are crucial in assessing the effectiveness of therapy and the progress of treatment. …”
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Importance of Modulating Kynurenic Acid Metabolism—Approaches for the Treatment of Dementia by Halina Baran, Marcelin Jan Pietryja, Berthold Kepplinger

“…Experimental pharmacological studies have shown that elevated levels of kynurenic acid in the brain are associated with impaired learning and that lowering kynurenic acid levels can improve these symptoms. …”
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Enrichment of Second Generation Ethanol Concentration Obtained from Napier Grass Pretreated with Sulfuric Acid and Hydrothermal Pretreatment by Phakeenuya Vanarat, Panakkal Elizabeth Jayex, Gundupalli Marttin Paulraj, Klinjapo Roungdao, Sriariyanun Malinee, Tantayotai Prapakorn

“…However, ethanol production was limited by elevated levels of inhibitors, such as acetic acid and furfural. …”
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Multi-Walled Carbon Nanotubes Accelerate Leukaemia Development in a Mouse Model by Qingqing Wang, Jingdan Han, Mujia Wei, Huikai Miao, Min Zhang, Biao Wu, Yao Chen, Yanwen Zheng, Robert Peter Gale, Bin Yin

“…Additionally, similar exposures elevated pro-inflammatory cytokines such as interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α and induced reactive oxygen species (ROS) in a murine macrophage cell line. …”
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The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting by Martina Kolackova, Jan Krejsek, Vladimir Svitek, Pavel Kunes, Jiri Mandak, Zdenka Holubcova, Vladimir Lonsky

“…The level of IL-10 is elevated by cardiac surgery when cardiopulmonary bypass (CPB) and methylprednisolone are used. …”
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Downregulation of Bcl-2 Expression by miR-34a Mediates Palmitate-Induced Min6 Cells Apoptosis by Xiaojie Lin, Hongyu Guan, Zhimin Huang, Juan Liu, Hai Li, Guohong Wei, Xiaopei Cao, Yanbing Li

“…Here, we showed that miR-34a was significantly induced in Min6 pancreatic β-cell upon palmitate treatment. Elevated miR-34a promoted Min6 cell apoptosis. Intriguingly, ectopic expression of miR-34a lowered the expression of Bcl-2, an antiapoptotic protein. …”
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Seronegative autoimmune hepatitis by A. O. Buyeverov

“…The number of articles devoted to SAH is quite low at the present time, while all of them are based on the small case series or single cases. Absence of elevated serum γ-globulins, immunoglobulin G and autoantibodies is most commonly seen in acute onset of the disease that is probably caused by delay of humoral immune response of the disease. …”
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