Serum Ferritin Levels in Pregnancy and Their Association with Gestational Diabetes Mellitus: A Prospective Longitudinal Study by Qin Z, Du Y, Wang Z, Qin X, Wu H, Yu X, Zhao C, Mo L, Huang B

“…SF was positively correlated with MDA and fasting plasma glucose (FPG). Elevated SF levels during early pregnancy were significantly associated with increased GDM risks (OR = 2.024, 95% CI: 1.076 – 3.807). …”
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Effect of probiotics combined with immune checkpoint suppressors and chemotherapeutic agents on digestive system function, intestinal immunity and prognosis in patients with metast... by Xiaolei Wang, Yuxia Huang, Zhen Yang, Yang Yang, Fenfen Wei, Min Yan, Fanfan Li, Chenghao Wang

“…D-lactate and diamine oxidase (DAO) levels were elevated in the intervention group after treatment, with smaller elevations (P < 0.05). …”
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The role of C-reactive protein in predicting all-cause mortality among Chinese arthritis patients: implications for public health education and promotion by Shuchao Ye, Damei Ye, Changyi Lin, Dongming Lu, Xuelan You, Chaoyan Xu, Yongyang Wu

“…Across three Cox regression models, elevated CRP levels (≥3 mg/L) were significantly associated with increased mortality risk [hazard ratio (HR) = 3.73 (2.23–6.23), HR = 3.00 (1.79–5.01), HR = 4.94 (1.77–13.78), respectively]. …”
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The prognostic role of cardiac and inflammatory biomarkers in extubation failure in patients with COVID-19 acute respiratory distress syndrome by Carline N. L. Groenland, Adinde H. Siemers, Eric A. Dubois, Diederik Gommers, Leo Heunks, Evert-Jan Wils, Vivan J. M. Baggen, Henrik Endeman

“…After multivariable adjustment for clinical variables (age, duration of mechanical ventilation, SOFA score), Hs-TnT was the only biomarker that was independently associated with extubation failure (adjusted OR 1.38, 95% CI 1.02–1.90). Patients with both elevated Hs-TnT (≥ 14 ng/mL) and elevated PCT (≥ 0.25 ng/mL) carried the highest risk of extubation failure (46%), while in patients with normal Hs-TnT and PCT values, only 13% experienced extubation failure. …”
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Analysis of the predictive value of the prostate-specific antigen-to-neutrophil ratio for the diagnosis of prostate cancer by Yuxuan Chen, Haisheng Yan, Yaoqin Xu, Kexin Chen, Runqin Yang, Jiali Yang, Ruian Zhu, Rui Lin, Jiang Wang, Jie Liu, Pingsheng Gao, Lei Pang, Lexin Wang

“…Results When PSA levels are in the range of 4–10 ng/ml, an elevated PNR is an independent risk factor for prostate cancer. …”
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Structural Disruption of Cilia and Increased Cytoplasmic Tubulin in Biliary Atresia—An Exploratory Study Focusing on Early Postoperative Prognosis Following Portoenterostomy by Patrícia Quelhas, Rui Oliveira, Carlos Kieling, Sandra Vieira, Jorge dos Santos

“…Cytoplasmic TUBA4A levels were elevated in BA patients. CRs positively correlated with lower cytoplasmic TUBA4A expression and was higher in patients without HIF-1α nuclear positivity. …”
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Immune profiling of human vestibular schwannoma secretions identifies TNF-α and TWEAK as cytokines with synergistic potential to impair hearing by Sasa Vasilijic, Richard Seist, Zhenzhen Yin, Lei Xu, Konstantina M. Stankovic

“…In vivo, we demonstrated that VS-secreted factors reach the inner ear, with elevated TNF-α and TWEAK in the perilymph and blood of tumor-bearing mice with impaired hearing. …”
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Association between the triglyceride-glucose index and liver fibrosis in adults with metabolism-related fatty liver disease in the United States: a cross-sectional study of NHANES... by Yuou Ying, Yuan Ji, Ruyi Ju, Jinhan Chen, Mingxian Chen

“…Conclusions In the general U.S. population, elevated TyG index levels were positively associated with an increased risk of LF in MAFLD patients.…”
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Anti-GAPDH Autoantibody Is Associated with Increased Disease Activity and Intracranial Pressure in Systemic Lupus Erythematosus by Jingjing Sun, Xue Li, Haotian Zhou, Xiaoyun Liu, Jingjing Jia, Qizhi Xie, Sijia Peng, Xiaolin Sun, Qingwen Wang, Li Yi

“…The serum levels of the anti-GAPDH autoantibodies were significantly elevated in the SLE patients, especially in the patients with NPSLE (P=0.0011). …”
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Phosphatidylinositol promoted the proliferation and invasion of pituitary adenoma cells by regulating POU1F1 expression by Tongjiang Xu, Xiaodong Zhai, RuiWei Wang, Xiaoben Wu, ZhiZhen Zhou, MiaoMiao Shang, Chongcheng Wang, Tengfei Qi, Wei Yang

“…In addition, PI propelled the metastasis of GH3 cells in vivo, and elevated the expression of PITPNM1, POU1F1, C2orf15 and LDHA. …”
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Identification and validation of glucose metabolism-related gene signature in endometrial cancer by Juan Jiang, Nan Xia, Mei Yang, Ping Qiu, Wei Zhu, Jing Chen, Jiamei Zhu

“…Abstract Background Metabolic syndrome associated with glucose metabolism plays a pivotal role in tumorigenesis, potentially elevating the risk of endometrial cancer (EC). This study sought to establish a glucose metabolism-related gene (GMRG) signature linked to EC. …”
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Prevalence and clinical correlates of chronic obstructive pulmonary disease in heart failure patients: a cross-sectional study in China by Ailing Zhu, Manman Hu, Dehai Ge, Xiujian Zhang, Jinfeng Zhang, Yangchun Wang, Xin Yao, Junjun Liu

“…Key risk factors included age, sex, elevated PaCO2, CCI score, and right heart failure, while higher SBP and triglyceride levels offered protection. …”
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Prevalence of neutropenia in the U.S. among reproductive-aged women: a population-based analysis of NHANES 2013–2020 by Junfeng Chen, Shuangna Song, Yiran Li

“…The logistic regression analysis indicated an elevated risk of neutropenia among black individuals and females with infertility. …”
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Prognostic Value of the Red Blood Cell Distribution Width-to-Albumin Ratio in Critically Ill Older Patients with Acute Kidney Injury: A Retrospective Database Study by Lei Guo, Dezhun Chen, Bihuan Cheng, Yuqiang Gong, Benji Wang

“…These results suggested that elevated levels of RA were linked to an elevated risk of 30-day, 90-day, and one-year all-cause death. …”
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CST2 promotes cell proliferation and regulates cell cycle by activating Wnt-β-catenin signalling pathway in serous ovarian cancer by Xiaohua Wang, Sufen Zhao, Yanwei Guo, Chunhui Wang, Shuyu Han, Xingcha Wang

“…Functionally, CST2 played vital roles in promoting cell proliferation, orchestrating the G1-to-S phase transition, and driving malignant SOC progression through activating the Wnt-β-catenin signalling pathway.Conclusions The elevated expression of CST2 may be related to the occurrence and progression of SOC by activating the Wnt-β-catenin pathway. …”
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Early childhood deprivation and the impact of negative life events on mental health in later life: a test of the stress sensitization hypothesis by Jala Rizeq, Mark Kennedy, Kirellos Miseih, Wangjingyi Liao, Edmund J. S. Sonuga-Barke

“…., autism/disinhibited social engagement)—the group of individuals exposed to early extreme deprivation and elevated peer-related LE had elevated emotional problems.DiscussionThere was no evidence that early severe institutional deprivation increased susceptibility to depression and anxiety following exposure to independent or dependent LE in general. …”
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A Retrospective Study in Trans Individuals Undergoing Gender Affirming Testosterone Treatment: Can Changes in Prolactin Counteract the Negative Effects on the Lipid Profile? by Jojo Steininger, Katalin Widmann, Ulrike Kaufmann, Marlene Hager, Rodrig Marculescu, Robert Krysiak, Johannes Ott

“…Recent data show that moderate prolactin (PRL) elevations might exert beneficial metabolic effects (“HomeoFIT-PRL model”). …”
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Adaptive mechanisms to hypoxia and hyperoxia in juvenile turbot, Scophthalmus maximus by Yi Chen, Yuntian Zhang, Rongwei Zhang, Hongsheng Deng, Xiangyu Meng, Kotoya Inaba, Tatsu Osato, Xiaoran Zhao, Xiaoran Zhao, Yuzhe Han, Yuzhe Han, Tongjun Ren, Tongjun Ren

“…Furthermore, genes ATP6, HIF1, HSP90, and CYP450 exhibited high expression levels during hypoxia, whereas Hbae5 and Man-SL showed elevated expression during hyperoxia. In hematological indicators, there are ways to help adapt to hypoxia and hyperoxia, including increased red blood cell (RBC) and hemoglobin (HGB) counts; gas and ion balance; elevated blood urea nitrogen (BUN) and malondialdehyde (MDA); increased polyphenol oxidase (PPO) and lysozyme (LZM) activity. …”
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Porphyromonas gingivalis associates with the presence of anti-citrullinated protein antibodies, but not with the onset of arthritis: studies in an at-risk population by Helga Westerlind, Linda Mathsson-Alm, Alexandra Circiumaru, Aase Hensvold, Karin Lundberg, Jan Potempa, Yogan Kisten, Charlotte De Vries, Marina Dehara, Barbara Potempa

“…Objective The antibody response against Porphyromonas gingivalis (Pg) is elevated in rheumatoid arthritis (RA), especially in patients with anti-citrullinated protein antibodies (ACPA). …”
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Brassinosteroid Enhances Cucumber Stress Tolerance to NaHCO₃ by Modulating Nitrogen Metabolism, Ionic Balance and Phytohormonal Response by Wenjing Nie, Biao Gong, Dan Wen, Peng Qiao, Hongen Guo, Qinghua Shi

“…This mitigation was accompanied by elevated concentrations of K⁺, Ca²⁺, and Mg²⁺, as well as enhanced expression of the <i>NHX</i> and <i>SOS1</i> genes. …”
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