Tumor-associated-fibrosis and active collagen-CD44 axis characterize a poor-prognosis subtype of gastric cancer and contribute to tumor immunosuppression by Yingqi Yang, Haohan Sun, Hongkai Yu, Luyao Wang, Chang Gao, Haokun Mei, Xiaomeng Jiang, Minghui Ji

“…Results A subtype of gastric cancer was identified with poor prognosis, characterized by higher malignancy, drug resistance, and poor immune infiltration, associated with elevated expression of genes related with Extracellular matrix (ECM). …”
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Fructose Consumption in Pregnancy and Associations with Maternal and Offspring Hepatic and Whole-Body Adiposity in Rodents: A Scoping Review by Grace Zhao, Sarah Chondon, Clint Gray, Sheridan Gentili, Meagan Stanley, Timothy RH Regnault

“…Hepatic adiposity was defined as elevated hepatic triglycerides or overall hepatic lipid accumulation. …”
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Serum cardiac and inflammatory biomarker levels following chemotherapy among female patients with breast cancer attending at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiop... by Muluabay Getie, Biset Asrade Mekonnen, Daniel Seifu, Yonas Mulugeta, Solomon Tebeje, Chernet Tafere, Asmare Amuamuta

“…In contrast, 15% of patients had baseline elevated CRP levels compared with their respective cutoff values. …”
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Using waist circumference as a predictor of hypertension in Manzese, Dar es Salaam: a community-based cross-sectional study, 2023 by Godbless Henry Mfuru, James N. Allan, Agnes Njau, Omary Ubuguyu, Khadija Y. Malima

“…Conclusion  This study reveals a high prevalence of hypertension among Manzese residents, with key risk factors including elevated waist circumference, age ≥ 35 years and a family history of hypertension. …”
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Diagnostic Value of High-Sensitivity Troponin T for Subclinical Left Ventricular Systolic Dysfunction in Patients with Sepsis by Pham Dang Hai, Nguyen Thanh Binh, Nguyen Hong Tot, Ha Manh Hung, Le Thi Viet Hoa, Nguyen Viet Quang Hien, Pham Nguyen Son

“…The median hs-cTnT level and the proportion of elevated hs-cTnT level (>14 ng/L) were significantly higher in patients with LVSD than in patients without LVSD. …”
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Infectious Aortitis with Abdominal Aortic Aneurysm in a 47-Year-Old Female with Systemic Lupus Erythematosus by Valerie R. Ramiro, Carmegie C. Saliba, John Anthony D. Tindoc, Marinette R. Jambaro, Enrique M. Chua, Donna Ricca M. Hornilla, Maria Teresa B. Abola

“…Complete blood count showed slight leukocytosis and elevated C-reactive protein. Abdominal imaging revealed a saccular infrarenal aneurysm with dissection. …”
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Temporal Trends in Serum Homer1 Levels and Their Prognostic Implications in Aneurysmal Subarachnoid Hemorrhage: A Prospective Cohort Study by Dai J, Lin Q, Ye L, Chen X, Li Z, Lu C, Chen M, Ba H, Sun J, Cai J

“…As demonstrated by a series of statistical methods, the model had a good performance.Conclusion: Serum homer1 levels are significantly elevated in acute phase after aSAH, and are strongly related to heightened bleeding intensity, poor 90-day prognosis and DCI. …”
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A bioprocess engineering approach for the production of hydrocarbons and fatty acids from green microalga under high cobalt concentration as the feedstock of high-grade biofuels by Alok Patel, Chloe Rantzos, Eleni Krikigianni, Ulrika Rova, Paul Christakopoulos, Leonidas Matsakas

“…It also exhibited 20.15 ± 1.03% of protein content including elevated levels of chlorophyll a, chlorophyll b, and carotenoids. …”
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Outcomes and physiologic responses associated with ketamine administration after traumatic brain injury in the United States and Canada: a retrospective analysis by Austin J. Peters, Saad A. Khan, Seiji Koike, Susan Rowell, Martin Schreiber

“…Ketamine exposure was associated with reduced elevations of ICP, more instances of seizure activity, and lower concentrations of TBI protein biomarkers.…”
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Opportunities for NCD screening and control efforts among people living with HIV/AIDS attending care and treatment clinic at a regional referral hospital in Dar es Salaam by Atuganile Musyani, Grace Mosi, Erik Kinyenje, Mucho Mizinduko, Rogath Kishimba, Meshack Shimwela, Leonard Subi

“…Of the nine patients with elevated blood glucose, 5 (55.5%) had normalized levels. …”
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Occurrence and assessment of chronic pain fatigue and sleep disturbance in axial spondyloarthritis patients by Eman Abdel Ghani Sayed, Samer Samy, Faruk Ali Abdi, Anna Abou-Raya

“…The relationship between fatigue, age, BMI, CRP, ESR, PSS, and HADS was not statistically significant.Conclusion The increased occurrence of sleep disorders, anxiety, depression, fatigue, and chronic pain and elevated ESR, CRP, HLA-B27, and disease activity scores with lowered QoL explain the association of these factors with disease comorbidities. …”
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IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M by Fernando Botelho, Anisha Dubey, Ehab A. Ayaub, Rex Park, Ashley Yip, Allison Humbles, Roland Kolbeck, Carl D. Richards

“…The IL-6-type cytokine Oncostatin M (OSM) elevates lung inflammation, Th2-skewed cytokines, alternatively activated (M2) macrophages, and eosinophils in C57Bl/6 mice in vivo. …”
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Endogenous 17β-estradiol regulates sexually dimorphic anxiety responses in zebrafish via the HPI axis and 5-HT/DA pathways by Hong Tao, Hong Tao, Ying–Ying Zhang, Ying–Ying Zhang, Yan–Jun Shen, Yan–Jun Shen, Qi–Liang Chen, Qi–Liang Chen, Zhi–Hao Liu, Zhi–Hao Liu

“…Females (C-F) showed significantly higher anxiety responses, along with elevated E2 and cortisol levels in plasma and brain, and reduced brain serotonin (5-HT) and dopamine (DA) levels compared to males (C-M). …”
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Protocol for a nested case-control study: identifying neuroimaging biomarkers for the progression of subclinical depression and qi-stagnation constitution to major depressive disor... by Jing Wang, Chengfeng Zhang, Yueqi Zhang, Yuanyuan Liu, Jingli Zhang, Xingwei Fang, Wangyang Xia, Yanzhao Xie, Zhongli Lan, Jinhui Wang, Jinhui Wang, Jinhui Wang, Jinhui Wang, Min Lu, Jun Chen, Jun Chen

“…Specifically, MDD in adolescents is linked to an elevated suicide risk. Thus, early identification and intervention is crucial for adolescents at high risk for developing MDD. …”
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Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders by Fancheng Liu, Fancheng Liu, Yazhen Su, Yazhen Su, Xinling Liu, Li Zhao, Li Zhao, Zewen Wu, Zewen Wu, Yang Liu, Yang Liu, Liyun Zhang, Liyun Zhang

“…Studies dating back to the 1970s have indicated elevated cfDNA concentrations in SLE. Currently, increased levels of cfDNA are noted in a range of rheumatic disorders. …”
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Efficient and accurate tobacco leaf maturity detection: an improved YOLOv10 model with DCNv3 and efficient local attention integration by Yi Shi, Hong Wang, Fei Wang, Yingkuan Wang, Jianjun Liu, Long Zhao, Hui Wang, Feng Zhang, Qiongmin Cheng, Shunhao Qing

“…This technique facilitates a rapid and non-invasive assessment of leaf maturity, significantly elevating the accuracy and efficiency of tobacco leaf quality evaluation. …”
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Evaluating the Diagnostic Value of Lymphocyte Subsets in Bronchoalveolar Lavage Fluid and Peripheral Blood Across Various Diffuse Interstitial Lung Disease Subtypes by Sonoko Harada, Motoyasu Kato, Kazuyuki Nakagome, Hitoshi Sasano, Yuki Tanabe, Tomohito Takeshige, Yuuki Sandhu, Kei Matsuno, Shoko Ueda, Sumiko Abe, Takayasu Nishimaki, Shun Shinomiya, Jun Ito, Sachiko Miyake, Ko Okumura, Makoto Nagata, Kazuhisa Takahashi, Norihiro Harada

“…SAR patients exhibited significantly elevated CD4/CD8 ratios in the BAL fluid, with a ratio of 3.95 or higher and type 1 innate lymphoid cell frequency ≥ 0.254% as differentiation markers. …”
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Non-thermal atmospheric plasma treatments enhance the growth, photosynthesis, metabolite accumulation, and nutritional value of geranium (Pelargonium graveolens L’Herit) leaves by Hussein S. Mohamed, Dalia Shehata, Ahmed M. Mahmoud, Maha H. Khalaf, Mohammad K. Okla, Mohamed A. El-Tayeb, Yasmeen A. Alwasel, Ibrahim A. Alaraidh, Ali El-Keblawy, Izabela Josko, Mohamed S. Sheteiwy

“…Antimicrobial activity was elevated across all treatments, with the T3 treatment notably inhibiting all tested bacterial and fungal strains, particularly Sarcina lutea. …”
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Effects of excessive body fat on colostrum lipid patterns: overweight/obese vs. normal weight mothers by Qian Liu, Yan Liu, Di Yang, Yanpin Liu, Yan Liu, Weicang Qiao, Juncai Hou, Yaling Wang, Minghui Zhang, Kai Yang, Xiaofei Fan, Ziqi Li, Junying Zhao, Lijun Chen

“…Further analysis of the fatty acid composition of TAGs revealed that elevated maternal body weight enhanced the concentration of TAGs containing saturated or n-6 fatty acids and shortened the carbon number of TAGs. …”
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Efficacy and safety of ondansetron orally soluble pellicle for preventing moderate- to high-emetic risk chemotherapy-induced nausea and vomiting by Lu Sun, Jia Ma, Yajuan Zhou, Xiaofang Ying, Gai Liang, Guoliang Pi, Ying Li, Yan Luo, Jianping Bi, Hanping He, Yi Peng

“…The most common adverse events were elevated levels of alanine transaminase (6.7%), elevated levels of aspartate transaminase (3.7%), fatigue (3.7%), and cough (2.5%). …”
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