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  1. 3161

    RELATIONSHIPS BETWEEN LIPID PROFILE AND COMPLETE BLOOD CELL COUNT PARAMETERS by Yevhen Dzis, Oleksandra Tomashevska, Andriy Petrukh

    Published 2022-12-01
    “…An atherogenic lipid profile is associated with increased counts of all blood cells, reflecting specific and nonspecific immune reactions in response to elevated levels of various lipid groups. Platelets play an important role in lipid metabolism. …”
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  2. 3162

    Impact of Hyperglycemia on Tear Film and Meibomian Gland Dysfunction: A Cross-Sectional Study by Meng F, Zhou Y, Bao T, Pang Y, Shao Q, Wang L, Zhao J, Li W, Xu H, Yang Y, Zhang B

    Published 2025-02-01
    “…Fasting blood glucose levels stratified patients into high (≥ 7 mmol/l) and normal (< 7 mmol/l) groups, and their association with DED parameters was analyzed.Results: Among 56 patients (mean age 52.5 ± 18.0 years), those with elevated glucose levels (n=28) had more severe DED symptoms (OSDI, p = 0.046), lower TMH, FNIBUT, ANIBUT, and higher bulbar redness scores (all p < 0.05). …”
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  3. 3163

    An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration by Qiyun Wang, Xinyuan Zhang, Kaiyue Wang, Ling Zhu, Bingjie Qiu, Xiaosi Chen, Xiao Lin, Yao Nie

    Published 2021-01-01
    “…Apoptosis was significantly elevated, but the proportion of RGCs with neurite extension was significantly lower in the 50 mM, 100 mM, and 150 mM groups (p50mM<0.001, p100mM<0.001, and p150mM<0.001). …”
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  4. 3164
  5. 3165

    Effect and Mechanism of Soluble Dietary Fiber from Corn Bran on Loperamide-induced Constipation in Mice by Xiangrui ZENG, Caixia JIANG, Xiaolan LIU, Xiqun ZHENG, Xuyao WEI

    Published 2025-02-01
    “…Compared to that of the model group, the levels of gastrointestinal tract-related neurotransmitters (motilin, 5-hydroxytryptamine, etc.) were elevated in mice that received CSDF, suggesting that CSDF could alleviate constipation in enteric nervous system disorders. …”
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  6. 3166

    Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer by Yun Teng, Hongmei Zhao, Guoqing Xue, Guohui Zhang, Yanbin Huang, Wei Guo, Kun Zou, Lijuan Zou

    Published 2025-01-01
    “…Among the 62 patients with cervical cancer, elevated MICAL2 expression was associated with a lower complete response rate to radiotherapy (25.6% vs. 60.9% in those with low expression), reduced progression-free survival, and advanced cancer stage (*p < 0.05). …”
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  7. 3167

    Exploring gender-based disparities in emotional distress among university level athletes by Sohom Saha, Farjana Akter Boby, Arnav Sharma, Sourav Ganguly, Kautilya Upadhyay, Awesh Khati, Dev Karan Singh, Kamal Dhoni, Debajit Karmakar

    Published 2025-01-01
    “…Volleyball's individual performance components may increase stress for male athletes, while basketball's physical demands might elevate depression levels among females. Handball's continuous play and physical contact likely contribute to elevated stress in female players. …”
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  8. 3168

    Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3 by Han Chu, Qi-Fei Deng, Yuan Fang

    Published 2025-01-01
    “…IntroductionCryptorchidism can damage cells in the cryptorchid testes due to elevated local temperatures, potentially impacting the fertility of the child in adulthood. …”
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  9. 3169

    The Association of Polycystic Ovary Syndrome and Gestational Hypertensive Disorders in a Diverse Community-Based Cohort by Diane Schneider, Joel R. Gonzalez, Miya Yamamoto, Jingrong Yang, Joan C. Lo

    Published 2019-01-01
    “…Preexisting hypertension was defined by hypertension diagnosis, treatment, or elevated blood pressure prior to 20 weeks of gestation. …”
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  10. 3170

    Reduction of Hepatic Fat Content by Dulaglutide for the Treatment of Diabetes Mellitus: A Two‐Centre Open, Single‐Arm Trial by Chuanfeng Liu, Yu Xin, Yajing Huang, Lili Xu, Ruizhi Zhou, Yangang Wang, Wei Wang

    Published 2025-01-01
    “…ABSTRACT Background With the elevated level of NAFLD prevalence, the incidence of diabetes, hypertension, metabolic syndrome and other diseases is also significantly elevated. …”
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  11. 3171

    The Impact of Preoperative Opioid Use Disorder on Complications and Costs following Primary Total Hip and Knee Arthroplasty by Jacob M. Wilson, Kevin X. Farley, Matthew Aizpuru, Eric R. Wagner, Thomas L. Bradbury, George N. Guild

    Published 2019-01-01
    “…Multiple studies have demonstrated that patients taking opioids in the preoperative period are at elevated risk for complications following total hip (THA) and knee (TKA) arthroplasty. …”
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  12. 3172

    Comparative Analysis of Tenogenic Gene Expression in Tenocyte-Derived Induced Pluripotent Stem Cells and Bone Marrow-Derived Mesenchymal Stem Cells in Response to Biochemical and B... by Feikun Yang, Dean W. Richardson

    Published 2021-01-01
    “…On the other hand, quantitative real-time PCR showed that TGF-β3 increased the expression of EGR1, COL1A2, FMOD, and TNC in BMSCs and SCX, COL1A2, DCN, FMOD, and TNC in teno-iPSCs. BMP12 treatment elevated SCX, MKX, DCN, FMOD, and TNC in teno-iPSCs. …”
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  13. 3173
  14. 3174

    Effects of Different Levels of Carbohydrates on Growth Performance, Hepatic and Intestinal Health, and Intestinal Microflora of Juvenile Pikeperch (Sander lucioperca) by Jie Zhao, Yang Liu, Zhipeng Sun, Liansheng Wang, Ze Fan, Yadan Pan, Jiamin Gao, Cuiyun Lu, Xianhu Zheng

    Published 2024-01-01
    “…In addition, proinflammatory cytokines, interleukin 1 beta (il1-β), interleukin 8 (il8), and tumor necrosis factor beta (tnf-β), in the liver and intestine elevate and anti-inflammatory cytokines, interleukin 10 (il10) and transforming growth factor beta (tgf-β), decrease with increasing dietary carbohydrate levels. …”
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  15. 3175

    Hepatitis due to Coxsackie A virus in an adult: a case report by Likith Surendra, Varun Sharma, Milan Sivakumar, Tara Lanzendorf, Thomas C. Varkey, Kaivan Salehpour

    Published 2025-02-01
    “…He was found to be febrile to 100.9 °F, with leukocytosis of 12.6 × 109 WBC/L, elevated liver function tests (LFTs) including aspartate aminotransferase (AST) of 386 U/L and alanine transaminase (ALT) of 260 U/L, and elevated total bilirubin of 2.2 mg/dL. …”
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  16. 3176

    Expression of CSTF2 in oral squamous cell carcinoma and its relationship with immune infiltration and poor prognosis by Zumulaiti Aierken, Muertiza Muhetaer, Zhang Lei, Ainiwaerjiang Abudourousuli, Ainiwaerjiang Abudourousuli

    Published 2025-02-01
    “…Additionally, the overexpression of CSTF2 exhibited a negative correlation with the infiltration of immature dendritic cells (iDCs), cytotoxic cells, and plasmacytoid dendritic cells (pDCs). Notably, elevated CSTF2 expression is significantly associated with reduced patient outcomes.ConclusionElevated CSTF2 expression in OSCC is associated with poor prognostic outcomes, highlighting its capacity to function as an innovative prognostic biomarker and a target for therapeutic interventions.…”
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  17. 3177

    Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

    Published 2025-01-01
    “…In addition to its role in disease pathology, CHI3L1 has emerged as a promising biomarker for the diagnosis and monitoring of brain disorders. Elevated cerebrospinal fluid (CSF) levels of CHI3L1 have been linked to disease severity and cognitive decline, particularly in AD and MS, highlighting its potential for clinical diagnostics. …”
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  18. 3178

    Prognostic value and clinicopathological significance of pre-and post-treatment systemic immune-inflammation index in colorectal cancer patients: a meta-analysis by Yueting Tan, Bei’er Hu, Qian Li, Wen Cao

    Published 2025-01-01
    “…The relationship between SII and survival outcomes was attenuated post-treatment compared to pre-treatment. Additionally, elevated SII was correlated with clinicopathological factors in CRC patients. …”
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  19. 3179
  20. 3180

    Association between systemic immune inflammation index and cataract incidence from 2005 to 2008 by Xiang Li, Guo-lei Du, Shi-Nan Wu, Yi-qing Sun, Si-Qi Zhang, Zhi-Jie Zhang, Jia-feng Tang

    Published 2025-01-01
    “…After adjusting for all covariates, multivariable logistic regression analysis demonstrated that elevated levels of the SII were significantly associated with increased odds of cataracts (Model1: OR = 1.56; 95%CI [1.33–1.85]; Model2: OR = 1.55; 95%CI [1.32–1.84]; Model3: OR = 1.57; 95%CI [1.33–1.86]). …”
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