Drug-Induced Liver Injury Associated with the Use of Everolimus in a Liver Transplant Patient by Serena Patel, Michel H. Mendler, Mark A. Valasek, Shirley M. Tsunoda

“…A 56-year-old Caucasian male liver transplant recipient developed DILI after receiving everolimus. Elevations in transaminase levels occurred within a week of starting everolimus and an upward trend in the transaminase levels continued with supporting histopathologic changes confirmed by liver biopsy. …”
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Lactate Gap: A Diagnostic Support in Severe Metabolic Acidosis of Unknown Origin by Linn E. Hauvik, Mercy Varghese, Erik W. Nielsen

“…We present a patient with severe metabolic acidosis and elevated lactate levels on the point-of-care analyzer. …”
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Identification and In Vitro Antimicrobial Susceptibility of Brucella Species Isolated from Human Brucellosis by Rohaidah Hashim, Norazah Ahmad, Jama’ayah Mohamed Zahidi, B. Y. Tay, Azura Mohd Noor, Sakina Zainal, Hazwani Hamzah, S. H. Hamzah, T. S. Chow, P. S. Wong, K. N. Leong

“…All isolates were noted to be sensitive to all the antimicrobial agents tested except for rifampicin where elevated MIC > 1 μg/mL was noted in 30 out of 41 isolates tested.…”
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Use of Anti-Interleukin-6 Receptor Monoclonal Antibody in Drug-Induced Acute Respiratory Distress Syndrome by Alessandra Petrillo, Noa Biran, Sean Sadikot

“…The parenchymal lung injury seen in ARDS is a result of many proinflammatory elevations including interleukin-6. There remains no effective standard of care of ARDS, and current treatments at this time currently do not target the immunological mechanisms or pathways involved. …”
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Disasters, their interaction with science, technology and society by Víctor René Navarro Machado

“…The diverse methodological and theoretical approaches flourished from social sciences to carry out disasters analysis, have pointed out the necessity of taking into consideration historical conditions that have generated them and that, at the same time, have elevated the vulnerability of affected societies. The historical dimension requires studying a given topic or problem in terms of its continuity in space and time, having the possibility of making stops in its way, analysing also the event, always engulfed in a space-time context that conditions and defines it. …”
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A Case of Coronary Vasospasm after Repeat Rituximab Infusion by Calvin Ke, Amit Khosla, Margot K. Davis, Cameron Hague, Mustafa Toma

“…Fifteen minutes after rituximab infusion commenced, she developed typical cardiac chest pain with ST segment elevations on electrocardiogram. Angiogram revealed evidence of coronary vasospasm. …”
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New Coronavirus Infection (COVID-19) and Digestive System by V. T. Ivashkin, A. A. Sheptulin, O. Yu. Zolnikova, A. V. Okhlobystin, E. A. Poluektova, A. S. Trukhmanov, E. N. Shirokova, M. I. Gonik, N. I. Trofimivskaya

“…Patients with chronic inflammatory bowel diseases receiving immunosuppressive therapy are at elevated risk of severe COVID-19 progression. The new coronavirus infection may induce liver damage with increased transaminase activity.Conclusion. …”
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Ocean Acidification: An Introduction by Joshua T. Patterson, Lisa S. Krimsky

“…It specifically explains the changes that are occurring to the chemistry of our coastal and oceanic waters because of elevated carbon dioxide levels. Additional publications address potential environmental, economic, and social implications for Florida.   …”
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Subacute parkinsonism induced by immune checkpoint inhibitors by Lénia Silva, Inês Laranjinha, Cláudia Casais, Raquel Samões

“…The investigation revealed only mild slowing of the background activity on electroencephalogram and slightly elevated cell count and protein levels in her cerebrospinal fluid. …”
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The role of the teacher in the university-society integration. by Mayra Sofia Gil

“…The aim of the medical university is to develop professionals with high moral values and an elevated qualification, able to face the always increasing and continuous demands of science, technology and society, aim that is achieved by means of the teaching learning process in which professors play a decisive role which is at the same time present in all the components of the process with a permanent example in the decisive contribution for improving quality and excellence at the university. …”
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Ocean Acidification: An Introduction by Joshua T. Patterson, Lisa S. Krimsky

“…It specifically explains the changes that are occurring to the chemistry of our coastal and oceanic waters because of elevated carbon dioxide levels. Additional publications address potential environmental, economic, and social implications for Florida.   …”
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Prognostic Value of PSMB5 and Correlations with LC3II and Reactive Oxygen Species Levels in the Bone Marrow Mononuclear Cells of Bortezomib-Resistant Multiple Myeloma Patients by Eva Plakoula, Georgios Kalampounias, Spyridon Alexis, Evgenia Verigou, Alexandra Kourakli, Kalliopi Zafeiropoulou, Argiris Symeonidis

“…Conversely, LC3II protein levels were elevated at both remission and relapse compared to baseline levels (<i>p</i>-value = 0.041). …”
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Assessment of the hypoglycemic effect of Cyanthillium cinereum (L.) H. Rob. and its dual impact on uterine contraction in gestational diabetic rats by Sasitorn Kerdsuknirund, Arreeya Kosinan, Panida Khunkaewla, Pakanit Kupittayanant, Pattama Tongdee, Porntip Nimkuntod, Susan Wray, Sajeera Kupittayanant

“…Results: CCE and metformin (MET) significantly reduced elevated blood glucose levels and improved the Islets of Langerhans area compared to the GDM group (P < 0.05). …”
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Genome sequencing enhances the diagnostic yield and expands the genetic landscape of male breast cancer by Wen Wen, Sen Zhao, Yiwen Jiang, Chengzhu Ou, Changyuan Guo, Ziqi Jia, Jiayi Li, Yansong Huang, Hengyi Xu, Pengming Pu, Tongxuan Shang, Lin Cong, Xiang Wang, Nan Wu, Jiaqi Liu

“…Elevated average polygenic risk score was noted compared with controls, with a significant correlation to early-onset MBC when combined with high-penetrance germline pathogenic variants (P = 1.10 × 10−4). …”
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Neutrophil-to-lymphocyte ratio and short-term mortality in patients having anti-MDA5-positive dermatomyositis with interstitial lung disease: a retrospective study by Hongxia Xin, Ping He, Bin Xi, Zhaojun Wang, Han Wang, Faxuan Wang, Zhanbing Ma, Jing Xue, Yuanyuan Jia, Hourong Cai, Bi Chen, Juan Chen

“…Conclusions We found that an elevated baseline NLR and its progressive increase are associated with 30-day mortality in patients with anti-MDA5-positive DM-ILD.…”
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Serum matrix metalloproteinase‐7, Syndecan‐1, and CA 19‐9 as a biomarker panel for diagnosis of pancreatic ductal adenocarcinoma by Doron Yablecovitch, Moshe Nadler, Shomron Ben‐Horin, Orit Picard, Miri Yavzori, Ella Fudim, Moran Tardio Duchan, Emad Sakhnini, Alon Lang, Maor Lahav, Talia Saker, Sandra Neuman, Limor Selinger, Biana Freitz, Revital Dvir, Maria Raitses‐Gurevich, Talia Golan, Idan Levy, Ido Laish

“…Results MMP‐7 median serum levels were significantly elevated in the PDAC (7.3 ng/mL) and cyst groups (3.7 ng/mL) compared with controls (2.9 ng/mL) (p < 0.001 and 0.02, respectively), and also between the PDAC and cyst groups (p < 0.001), while SDC1 median serum levels were significantly elevated in PDAC (43.3 ng/mL) compared with either cysts (30.1 ng/mL, p < 0.001) or controls (31.2 ng/mL, p < 0.001). …”
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Impact of high hemoglobin levels on carotid artery intima–media thickness and its predictive value for hypertension in high-altitude areas: a real-world study by Long Hongyu, Long Ga, Zhang Yiqian, Xu Qiuyu, Li Kemin, Qing Maiyongcuo, Xiong Min

“…The area under the ROC curve for predicting hypertension with elevated hemoglobin level was 0.799 (0.719–0.880).ConclusionElevated hemoglobin levels contribute to the thickening of the carotid artery intima–media layer and hold predictive value for high-altitude hypertension.…”
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Effect of different feeding regimes in amur common carp fingerlings: compensatory growth, physio-metabolic responses, and expression of IGF-1 gene by Chowdhury Arka, Ghosh Tapas Kumar, Khatua Sanjib, Hore Sayani, Kumari Palak, Kajal Kumari, Jana Prasanta

“…T2/1 asserted superior digestive capacity in the starved group, with elevated (P < 0.05) protease and amylase activity. …”
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S100A8/A9 Molecular Complexes Promote Cancer Migration and Invasion via the p38 MAPK Pathway in Nasopharyngeal Carcinoma by Ning Xu, Bei-Bei Zhang, Xia-Ning Huang, Xiang Yi, Xue-Min Yan, Yan Cai, Qin He, Zi-Jian Han, Yuan-Jiao Huang, Wei Liu, Ai-Jun Jiao

“…We previously discovered S100A8/A9 levels were roughly elevated in the plasma of NPC patients as the promising biomarkers. …”
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The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review by Theodoros Karampitsakos, Despoina Mavrogianni, Nikolaos Machairiotis, Anastasios Potiris, Periklis Panagopoulos, Sofoklis Stavros, Panos Antsaklis, Peter Drakakis

“…Conclusions: Elevated IL-6 levels and specific gene polymorphisms are strongly associated with preterm delivery risk, with IL-8 concentrations correlating with systemic inflammation and histologic chorioamnionitis. …”
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