Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity by Sudershana Nair, Nicholas E Baker

“…Within emc mutant clones, Notch signaling was elevated in the morphogenetic furrow, increasing morphogenetic furrow speed. …”
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A Study on the Clinico-serological Features of Nail Psoriasis by Ratnika, Mohammad Adil, Syed Suhail Amin

“…NPQ10 demonstrated associations with NAPSI (P < 0.001, β = 0.83) and PASI (P = 0.001, β = 0.83). Elevated ESR and CRP levels were associated with higher NAPSI scores (P < 0.001, β = 0.55, and P = 0.003, β = 0.43, respectively). …”
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The impact of SLCO1B1 polymorphisms on homocysteine concentrations: evidence for a stronger association in men by Xinyuan Hu, Yanfang Jiang

“…Univariate logistic analysis identified gender, GGT concentrations, B12 concentrations, folic acid concentrations, and SLCO1B1 c.521 CC+CT polymorphism as risk factors for elevated Hcy. Multivariate logistic analysis confirmed that B12 concentrations, folic acid concentrations, and SLCO1B1 CT + CC polymorphism were significant dependent risk factors. …”
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Statistical Characteristics of Total Electron Content Intensifications on Global Ionospheric Maps by X. Meng, O. P. Verkhoglyadova, S. C. Chapman, N. W. Watkins, M. Cafolla

“…The strength of intensifications also increases with elevated geomagnetic activity, but the number of intensifications does not. …”
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Effects of Renal Denervation on Ouabain-Induced Hypertension in Rats by Minna Tang, Jialu Hu, Wenshu Li, Ningzhi Zhang, Sisi Ning, Yan Yan, Zhaoqiang Cui

“…Ouabain, a Na+, K+-ATPase inhibitor, is elevated in hypertensive patients. Evidence suggests ouabain contributes to hypertension mainly through activation of the sympathetic nervous system (SNS). …”
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Modulation of Cytokine and Cytokine Receptor/Antagonist by Treatment with Doxycycline and Tetracycline in Patients with Dengue Fever by J. E. Z. Castro, I. Vado-Solis, C. Perez-Osorio, T. M. Fredeking

“…Similarly, IL-1RA and TNF-R1 serum concentrations were elevated at baseline and showed a moderate increase among untreated patients. …”
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Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness by Sahithi Attaluri, Raghavendra Upadhya, Maheedhar Kodali, Leelavathi N. Madhu, Dinesh Upadhya, Bing Shuai, Ashok K. Shetty

“…The circulating blood in GWI rats displayed elevated proinflammatory cytokines with no alterations in CysLT and LTB4 concentrations. …”
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Identification of Predictive Factors for Massive Transfusion Activation in Trauma Patients: A Systematic Review and Meta-analysis by Thosapol Ueamsaranworakul, Ratcharin Niamjumnong, Kumpol Kornthatchapong, Winchana Srivilaithon

“…Conclusion: Several physiological parameters: low SBP, elevated HR, reduced Hb, increased INR, diminished BE, and elevated lactate are significantly correlated with an increased likelihood of necessitating MTP in trauma patients. …”
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Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? by Mieke A. van der Mescht, Helen C. Steel, Ronald Anderson, Theresa M. Rossouw

“…We propose that the elevated levels of VEGF-A observed during HIV/SARS-CoV-2 co-infection originate predominantly from activated immune cells due to the upregulation of HIF-1α by damaged endothelial cells. …”
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Clinical Outcomes in Patients with Cardiac Lupus: A Retrospective Study by K Maria Koshy, Tarun George, Sohini Das, J V Punitha, Sudha Jasmine Rajan, Bijesh Yadav, Thambu David Sudarsanam, Vijay Prakash Turaka

“…The inpatient mortality rate was 22% (n = 13). An elevated serum creatinine, elevated creatine Kinase–muscle/brain, neutrophilic leukocytosis, left ventricular systolic dysfunction, noninitiation of hydroxychloroquine, and the presence of neuropsychiatric lupus predicted mortality. …”
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Incidence of prostate adenocarcinoma in transurethral resection of the prostate patients by Yahia Ghazwani, Abdullah Alhaider, Rakan Aldharab, Faisal Aldumiaikhi, Nasser Albogami, Abdulaziz Alathel, Ali Alothman, Raghib Abusaris, Mosaad Alshahwan, Fahad Alhamad, Ziyad Aljaafri, Khalid Alduraibi

“…Multivariable logistic regression analysis indicated that elevated PSA density, ischemic heart disease, and chronic kidney disease, significantly influenced the likelihood of IPCa (P < 0.05). …”
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Diplopia, Convergent Strabismus, and Eye Abduction Palsy in a 12-Year-Old Boy with Autoimmune Thyroiditis by Pedro Marques, Sandra Jacinto, Maria do Carmo Pinto, Catarina Limbert, Lurdes Lopes

“…Laboratorial evaluation revealed elevated free thyroxine level (1.05 ng/dL [0.65–1.01]) and low TSH, without other alterations. …”
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The relationship between work disability and subsequent suicide or self-harm: A scoping review. by Alex Collie, Shannon Elise Gray

“…The risk of suicide and self-harm is elevated in people experiencing work disability. Further observational research is required to fill evidence gaps. …”
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Maternal and Umbilical Cord Heat-Shock Protein 70 Levels in Patients with Gestational Diabetes Mellitus by Aybike Tazegul, Sedat Abuşoğlu, Görkem Aktaş, Nasuh Utku Doğan, Berat Berrin Gençoğlu Bakbak, Cetin Celik, Ali Unlu, Özlem Seçilmiş, Ayşegül Kebapçılar, Setenay Yılmaz, Mete Bertizlioğlu

“…The obtained results seem to indicate that elevated umbilical cord Hsp-70 values may potentially be used as indicators of risk factor for early term delivery in pregnancies.…”
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Pharmacological Evaluation of Naproxen Metal Complexes on Antinociceptive, Anxiolytic, CNS Depressant, and Hypoglycemic Properties by Md. Sharif Hasan, Narhari Das, Zobaer Al Mahmud, S. M. Abdur Rahman

“…The antinociceptive activity was evaluated by acetic acid-induced writhing method and radiant heat tail-flick method while anxiolytic activity was evaluated by elevated plus maze model. The CNS depressant activity of naproxen metal complexes was assessed using phenobarbitone-induced sleeping time test and the hypoglycemic test was performed using oral glucose tolerance test. …”
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Cilostazol Combats Lipopolysaccharide-Induced Hippocampal Injury in Rats: Role of AKT/GSK3β/CREB Curbing Neuroinflammation by Doaa Abou El-ezz, Waleed Aldahmash, Tuba Esatbeyoglu, Sherif M. Afifi, Marawan Abd Elbaset

“…Furthermore, cilostazol administration suppressed LPS-induced rises in hippocampus caspase-3 and NF-κB levels while elevating rat B-cell/lymphoma 2 (BCL2) and brain-derived neurotrophic factor (BDNF) levels, which are implicated in neuronal survival and synaptic plasticity. …”
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Asiaticoside Suppresses Gastric Cancer Progression and Induces Endoplasmic Reticulum Stress through the miR-635/HMGA1 Axis by Chao Zhang, Xiaolin Ji, Zhenguang Chen, Zhichao Yao

“…AC inhibited the expressions of the cell proliferation marker PCNA and EMT-related marker N-cadherin and increased E-cadherin expression. AC elevated the levels of GRP78 and Chop and suppressed the level of hnRNPA1. …”
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Prevalence of metabolic syndrome and its risk factors among the government bank’s employees of district Bijnor, Uttar Pradesh: A cross-sectional study by Ajay Kumar Prajapati, Ruchi Prajapati

“…The various risk factors affecting the MetS are elevated serum triglyceride level, elevated fasting blood glucose (FBG), raised BP, enlarged WC, etc., The majority of individuals had a high risk of health status 27 (42.1%) and a moderate level of stress, i.e., 38 (59.4%), respectively. …”
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Endothelial molecule levels (VCAM-1, ICAM-1) in uncomplicated malaria cases in Lagos, Nigeria by Uche T. Igbasi, Wellington A. Oyibo

“… Background. Elevated endothelial activation markers are linked to malaria syndromes due to the sequestration of Plasmodium falciparum-infected red blood cells in deep tissue vessels. …”
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Deciphering the Impact of miR-92a-3p on Controlling BCL11A Gene Expression and Its Implication in Easing Thalassemia Symptoms by Mohammed M. Salih Al-Khafaji, Anas Y. Al-Hayawi

“…Conclusion: The findings of this study propose that through the suppression of BCL11A, miR-92a may elevate γ-globin levels while concurrently mitigating oxidative stress in blood cells.…”
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