Naringenin, a Food Bioactive Compound, Reduces Oncostatin M Through Blockade of PI3K/Akt/NF-κB Signal Pathway in Neutrophil-like Differentiated HL-60 Cells by Na-Ra Han, Hi-Joon Park, Seong-Gyu Ko, Phil-Dong Moon

“…While exposure to granulocyte-macrophage colony-stimulating factor (GM-CSF) induced elevated OSM release and mRNA expression, the elevated OSM release and mRNA expression were diminished by the addition of NAR in dHL-60 cells. …”
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Ceruloplasmin and the Extent of Heart Failure in Ischemic and Nonischemic Cardiomyopathy Patients by Yifei Xu, Haiyan Lin, Ying Zhou, Gang Cheng, Geng Xu

“…Objective. Ceruloplasmin was elevated in patients with coronary heart disease, but the relationship between ceruloplasmin and heart failure was still unknown. …”
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Impact of short-term soil disturbance on cadmium remobilization and associated risk in vulnerable regions by Zhong Zhuang, Hao Qi, Siyu Huang, Qiqi Wang, Yanan Wan, Huafen Li

“…Random Forest analysis identified elevated dissolved organic matter and pH changes as key drivers of Cd remobilization. …”
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Intention to utilize mental health and suicide prevention resources in a community sample during the first year of the COVID-19 pandemic by Lisa J. Cohen, Rawad El Hayek, Benedetta Imbastaro, Inna Goncearenco, Sifan Zheng, Megan L. Rogers, Maurizio Pompilli, Igor Galynker

“…These help-seeking patterns can be explained in part by an elevated level of SCS symptoms, suggesting greater levels of distress were driving expressed intention to utilize service referrals.…”
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Implications of hormonal carcinogenesis for transgender and gender-diverse people undergoing gender-affirming hormone therapy: an up-to-date review by Matteo Lambertini, Filippo Pietrantonio, Dario Trapani, Francesco Perrone, Rossana Berardi, Saverio Cinieri, Chiara Cassani, Amelia Barcellini, Filippo Ghelardi, Alberto Giovanni Leone, Stefania Bonadonna, Marianna Sirico, Barbara Tagliaferri, Stefano Maccarone, Davide Dalu, Lorenzo Ruggieri, Simone Nardin, Nicla La Verde

“…Transgender and gender-diverse (TGD) individuals face an elevated risk of cancer in comparison with the general population. …”
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IgG, IgM, and IgA Antinuclear Antibodies in Discoid and Systemic Lupus Erythematosus Patients by Sheridan A. Jost, Lin-Chiang Tseng, Loderick A. Matthews, Rebecca Vasquez, Song Zhang, Kim B. Yancey, Benjamin F. Chong

“…IgG antinuclear antibodies (ANAs) are elevated in patients with systemic lupus erythematosus (SLE) compared with patients with discoid lupus erythematosus (DLE). …”
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Aspiration can decline epidemic disease by Khadija Khatun, Md. Mamun-Ur-Rashid Khan, Jun Tanimoto

“…Lower aspiration levels contribute to vaccine hesitancy, elevating SED, and infection rates. Surpassing an aspiration threshold redirects preferences towards vaccination, aligning with socially optimal scenarios and alleviating social dilemmas. …”
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Association between Pan‐Immune Inflammation Value and Sarcopenia in Hypertensive Patients, NHANES 1999–2018 by Lu Long, Bingquan Xiong, Zhidan Luo, Haiyan Yang, Qiang She

“…These findings highlight the importance of early identification and management of elevated PIV levels to improve outcomes for hypertensive patients at risk of sarcopenia.…”
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Mycoplasma pneumoniae Infection in Children Is a Risk Factor for Developing Allergic Diseases by Qing Ye, Xiao-Jun Xu, Wen-Xia Shao, Yan-Xiang Pan, Xue-Jun Chen

“…MPP patients with allergic conditions had increased serum IgE levels and increased IL-4/INF-γ ratio, and IgE and Eosinophil Cationic Protein were further elevated in patients who eventually developed secondary asthma changes. …”
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PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells by Kimiyoshi Yano, Megumi Kato, Syoju Endo, Taichi Igarashi, Ryoga Wada, Takashi Kohno, Astrid Zimmermann, Heike Dahmen, Frank T. Zenke, Bunsyo Shiotani

“…Abstract DNA replication stress (RS), a prevalent feature of various malignancies, arises from both genetic mutations and genotoxic exposure. Elevated RS levels increase the vulnerability of cancer cells to ataxia telangiectasia and Rad3-related kinase inhibitors (ATRis). …”
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Hyperuricemia: An Early Marker for Severity of Illness in Sepsis by Sana R. Akbar, Dustin M. Long, Kashif Hussain, Ahmad Alhajhusain, Umair S. Ahmed, Hafiz I. Iqbal, Ailia W. Ali, Rachel Leonard, Cheryl Dalton

“…Conclusion. We report that elevated uric acid levels on arrival to the MICU in patients with sepsis are associated with poor prognosis. …”
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Inflammatory Response in Preterm and Very Preterm Newborns with Sepsis by Enrique Segura-Cervantes, Javier Mancilla-Ramírez, Jorge González-Canudas, Erika Alba, René Santillán-Ballesteros, Deneb Morales-Barquet, Gabriela Sandoval-Plata, Norma Galindo-Sevilla

“…The levels of C-RP, SC5b-9 (innate immune response mediators), and IL-10 or IL-4 (anti-inflammatory cytokines) were elevated during sepsis in both groups. IFN-γ, TNF-α, and IL-6 (proinflammatory cytokines) were differentially elevated only in PT neonates. …”
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Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, Colombia by Berta Nelly Restrepo, Leidy Diana Piedrahita, Ivony Yireth Agudelo, Gabriel Parra-Henao, Jorge E. Osorio

“…This difference was not statistically significant. Pulse was elevated, and systolic arterial pressure was lower in dengue cases compared with other febrile illness (P<0.05). …”
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Unusual Case of Localized Upper Limbs and Truncal Edema Associated with Fever, Anemia, and Acute Kidney Injury by Mohammad Tinawi

“…He was noted to have elevated creatine kinase, and a diagnostic muscle biopsy lead to diagnosis of inflammatory myositis. …”
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A Case Report of Peritoneal Tuberculosis: A Challenging Diagnosis by Dilara Bulut Gökten, Bilal Katipoglu, Ekrem Basara, Ihsan Ates, Nisbet Yılmaz

“…Peritoneal tuberculosis is a disease which can mimick malignancy especially in women who present with ascites and elevated CA125 levels. It should always be considered in differential diagnosis, but the diagnosis is rarely easy for clinicians. …”
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Innovating the science of agricultural development: 2025 state of the journal report by T. Grady Roberts, Amy Harder, James R. Lindner

“…First, we formed a new partnership to elevate the digital presence of research published in AAD. …”
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The Role of Visfatin, Leptin, and IL-18 in Polycystic Ovarian Syndrome Patients by Sukayna H. Rashed, Eman A. Hadi

“…Patients with PCOS had significantly elevated serum IL-18 and visfatin levels but normal leptin concentrations. …”
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Clinical Efficacy and Safety Analysis of Levofloxacin for the Prevention of Infection after Traumatic Osteoarthrosis and Internal Fixation: Systematic Review and Meta-Analysis by Weiliang Wang, ChuanQi Zou, Jie Zhang

“…In the clinical use of levofloxacin, adverse drug reactions including fever, elevated white blood cell count, and wound infection should be concerned.…”
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Tjalma syndrome: A rare manifestation of systemic lupus erythematosus by Ashwaq Alhmoudi, Ahlam Almarzooqi, Maryam Alahmad, Amna Al Muhairi, Sehriban Diab, Raven Haan, Khalid Elsayed

“…Further evaluation showed elevated CA-125 levels and pleural effusions, with no atypical cells. …”
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Serum Cytokines in Young Pediatric Patients with Congenital Cardiac Shunts and Altered Pulmonary Hemodynamics by Leína Zorzanelli, Nair Yukie Maeda, Mariana Meira Clavé, Vera Demarchi Aiello, Marlene Rabinovitch, Antonio Augusto Lopes

“…At catheterization, they had elevated pulmonary vascular resistance (5.7 [4.4–7.4] Wood units·m2, geometric mean with 95% CI). …”
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