Enhanced antitumor activity of combined hepatic arterial infusion chemotherapy with Lenvatinib and PD-1 inhibitors in unresectable hepatocellular carcinoma: a meta-analysis by Lingling Zhao, Cheng Xu, Jiewen Deng, Yang Ni

“…The AEs classified as grade 3 or above were elevated in the HAIC-L-P group, with notable risk ratios for vomiting, elevated AST, elevated ALT, thrombocytopenia, neutropenia, and hyperbilirubinemia. …”
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Does Sex Matter in Obesity-Induced Periodontal Inflammation in the SS^LepR Mutant Rats? by Abdulmohsin Alhashim, Kim Capehart, Jocelyn Tang, Karim M. Saad, Rafik Abdelsayed, Marion A. Cooley, Jan M. Williams, Ahmed A. Elmarakby

“…<b>Results:</b> Body weight, insulin, hemoglobin A1c and cholesterol levels were significantly elevated in the obese SS^LepR mutant strain vs. the lean SS strain within the same sex. …”
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Real‐world clinical diagnostics of heart failure patients with reduced or preserved ejection fraction by Jenni Huusko, Timo Purmonen, Iiro Toppila, Mariann Lassenius, Heikki Ukkonen

“…Also, a large proportion of patients did not have HF diagnosis, yet they presented elevated NT‐proBNP concentrations and clinical characteristics resembling those of HFpEF patients.…”
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Persistently high concentrations of β-hydroxybutyrate affect hepatic SOD2 expression and blood SOD activity in high-yielding dairy cows by Dominika Grzybowska, Katarzyna Żarczyńska, Przemysław Sobiech, Paweł Brym, Dawid Tobolski

“…Abstract Background Elevated BHB levels are hypothesized to influence hepatic antioxidant enzyme expression and activity, contributing to oxidative response. …”
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Association of composite dietary antioxidant index with circadian syndrome: evidence from NHANES by Chen Chen, Chenyu Zhao, Hongyu Jin, Zhiping Jiang, Wei Wang, Wen-Yang Li

“…Logistic regression revealed that the highest quartile of CDAI was inversely associated with the risk of CircS {odds ratio (OR) [95% CI = 0.69 (0.55–0.87)]} and the risk of depression [OR = 0.59 (0.48–0.72)], short sleep duration [OR = 0.54 (0.41–0.70)], elevated fasting glucose [OR = 0.80 (0.65–0.98)], elevated triglycerides (TG) [OR = 0.74 (0.59–0.92)], elevated waist circumference [OR = 0.65, (0.52–0.80)] and reduced high-density lipoprotein cholesterol (HDL-C) [OR = 0.75 (0.61–0.92)], respectively. …”
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Dim blue light at night worsens high-fat diet-induced kidney damage via increasing corticosterone levels and modulating the expression of circadian clock genes by Wenji Ren, Zixu Wang, Yulan Dong, Jing Cao, Ting Gao, Qingyun Guo, Yaoxing Chen

“…Additionally, dBL activated the NF-κB signaling pathway and resulted in elevated protein levels of TLR4, p-IκB, p-P65, and TNF-α. …”
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Interaction between 24 h Urinary Free Cortisol and Obesity in Hypertension-Mediated Organ Damage in Patients with Untreated Hypertension by Gao-Zhen Cao, Jia-Yi Huang, Qing-Shan Lin, Cong Chen, Min Wu, Run Wang, Ming-Yen Ng, Kai-Hang Yiu, Jian-Cheng Xiu

“…Conclusions: Elevated 24 h UFC levels were associated with higher severity of HMOD, including more frequent LVH, albuminuria, and greater CIMT. …”
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The neutrophil–lymphocyte ratio as a risk factor for all-cause mortality among individuals with resolved HBV infection: evidence from the NHANES 1999–2018 by Chen Qiu, Chaojie Yu, Lanlan Yang, Siqi Liu, Qian Zhang, Shengnan Jia, Wenrui Wang, Zhenjing Jin, Dongdong Yu

“…Our study aimed to investigate the correlation between elevated NLR levels and the risk of all-cause mortality in patients with resolved HBV infection. …”
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The effect of prednisolone ingestion and acute exercise on lipocalin-2 and its variants in young men: a pilot randomised crossover study by Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

“…C87A, but not LCN2 or its other variants, remained elevated at 180 min post-ex (p = 0.007). LCN2, but not its variants, was elevated in response to prednisolone ingestion. …”
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Isolated tubercular dacryoadenitis in a non-immunocompromised healthy adult by Ajax Jossy, N Kaviyapriya, Nirupama Kasturi, Sree J Rekha

“…A middle-aged woman presented with a slowly enlarging mass in the right superotemporal orbit and ptosis. The patient had an elevated erythrocyte sedimentation rate, and incisional biopsy showed granulomatous inflammation with Langhan's giant cells suggestive of a tubercular etiology. …”
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POTS and Antiphospholipid Syndrome: An Unlikely Association by Kalvin Zee, Shakaib Qureshi

“…This case presentation involves a 39-year-old patient identified as female who has been diagnosed with POTS and elevated anticardiolipin antibodies.…”
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Salmonella enterica Serotype Typhi Bacteremia Complicating Pregnancy in the Third Trimester by George F. Guirguis, Krunal Patel, Lisa Gittens-Williams, Joseph J. Apuzzio, Kristina Martimucci, Shauna F. Williams

“…Typhi should be considered in febrile patients with recent travel presenting with abdominal discomfort with or without elevated liver enzymes.…”
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Effects of early maternal care on anxiety and threat learning in adolescent nonhuman primates by Elyse L. Morin, Erin R. Siebert, Brittany R. Howell, Melinda Higgins, Tanja Jovanovic, Andrew M. Kazama, Mar M. Sanchez

“…Baseline startle was higher in MALT animals, suggesting elevated state anxiety. No differences in threat learning, or threat/safety discrimination were detected. …”
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Effects of Acute Endurance Exercise on Plasma Protein Profiles of Endurance-Trained and Untrained Individuals over Time by Marius Schild, Gerrit Eichner, Thomas Beiter, Martina Zügel, Ilke Krumholz-Wagner, Jens Hudemann, Christian Pilat, Karsten Krüger, Andreas M. Niess, Jürgen M. Steinacker, Frank C. Mooren

“…Among these A2Macro and IL-5 were higher in EET individuals while leptin showed elevated levels in SED individuals. Fifteen variables revealed group and time differences with elevated levels for IL-3, IL-7, IL-10, and TNFR2 in EET individuals. …”
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Second-Hand Smoke Increases Bronchial Hyperreactivity and Eosinophilia in a Murine Model of Allergic Aspergillosis by Brian W. P. Seymour, Edward S. Schelegle, Kent E. Pinkerton, Kathleen E. Friebertshauser, Janice L. Peake, Viswanath P. Kurup, Robert L. Coffman, Laurel J. Gershwin

“…All Af sensitized mice produced elevated levels of IL4, IL5 and IL10 but no IFN-γ indicating a polarized Th2 response. …”
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Association of Sociodemographic Variables and Healthy Habits with Body and Visceral Fat Values in Spanish Workers by María Gordito Soler, Ángel Arturo López-González, Pedro Juan Tárraga López, Emilio Martínez-Almoyna Rifá, Cristina Martorell Sánchez, María Teófila Vicente-Herrero, Hernan Paublini, José Ignacio Ramírez-Manent

“…<i>Results</i>: Both the average values and the prevalence of elevated body and visceral fat increase with age and decrease with social class and lower levels of physical activity. …”
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Pentraxin 3 Is a Predictor for Fibrosis and Arterial Stiffness in Patients with Nonalcoholic Fatty Liver Disease by Kadir Ozturk, Omer Kurt, Tolga Dogan, Alptug Ozen, Hakan Demirci, Fatih Yesildal, Murat Kantarcioglu, Turker Turker, Ahmet Kerem Guler, Yıldırım Karslioglu, Battal Altun, Ahmet Uygun, Sait Bagci

“…This study demonstrated that for the first time there is a close association between elevated PTX3 levels and increased arterial stiffness in patients with NAFLD.…”
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Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis by Laura R. R. Ribeiro, Flávio V. Loures, Eliseu F. de Araújo, Cláudia Feriotti, Tânia A. Costa, Carlos Henrique Serezani, Sonia Jancar, Vera L. G. Calich

“…This study showed for the first time that inhibition of CysLTs signaling results in less severe pulmonary paracoccidioidomycosis that occurs in parallel with elevated LX activity and reduced infection of macrophages.…”
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Mental Health Impacts of the COVID-19 Pandemic on Australian Children and Adolescents with a Medical Condition: Longitudinal Findings by Louise M. Crowe, Cathriona Clarke, Dan Geraghty, Ben Collins, Stephen Hearps, Remy Pugh, Nicola Kilpatrick, Emma Branson, Jonathan M. Payne, Kristina Haebich, Natalie McCloughan, Christopher Kintakas, Genevieve Charles, Misel Trajanovska, Ivy Hsieh, Penelope L. Hartmann, Sebastian King, Nicholas Anderson, Vicki Anderson

“…Young people (<18 years) with medical conditions have an elevated risk of mental health problems and may have been disproportionately affected by the distress associated with the COVID-19 restrictions. …”
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The pathomechanism of bone marrow edema in the femoral head necrosis with pericollapse stage by Liang Mo, Zhangzheng Wang, Mengyu Jiang, Chi Zhou, Chao Ma, Yinuo Fan, Wei He, Zhenqiu Chen, Yuhao Liu

“…These factors collectively elevated the risk of collapse or re-collapse. Targeted interventions aimed at neutralizing these risk factors show potential in slowing down the progression of the disease.…”
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