The Dynamic Changes of COL11A1 Expression During the Carcinogenesis and Development of Breast Cancer and as a Candidate Diagnostic and Prognostic Marker by Yuli Wang, Jing Wang

“…Conclusions: COL11A1 expression varies during breast tumor initiation and progression, with elevated levels linked to worse prognoses. These findings underscore COL11A1’s potential as a biomarker in breast cancer, suggesting its assessment could enhance diagnostic and prognostic strategies for more personalized patient management.…”
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Recognising the intricate relationship between uric acid and diabetes and its impact on ocular diseases by Soumya Ramani, Smriti Harish

“…He also gave a history of a nonhealing foot ulcer, hyperuricemia, and elevated serum creatinine. After examination, a provisional diagnosis of crystalline maculopathy associated with hyperuricemia was made.…”
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A Rare and Intriguing Case of Wilson's Disease Initially Suspected of Systemic Lupus Erythematosus by Mandana Khodashahi, Najmeh Mohajeri, Moeid Reza Alipour, Reza Khademi, Nama Mohamadian Roshan, Behzad Aminzadeh, Muhammed Joghatayi

“…., positive anti‐double‐stranded DNA antibody, low complement component 3) are inconsistent with physical findings, such as the absence of arthritis or nephritis, clinicians should consider diagnoses such as Wilson's disease, especially in the presence of abnormal liver function and elevated international normalized ratio (INR).…”
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Inflammatory Markers and Risk of Parkinson’s Disease: A Population-Based Analysis by Hongping Wang, Wenqiang Li, Qun Lai, Qian Huang, Hao Ding, Zhiping Deng

“…Conclusions: There was a significant association between elevated levels of NLR, PLR, and PD risk, while LMR, SIRI, and SII were not statistically significant. …”
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Effect of a Hemodialysis Session on Markers of Inflammation and Endotoxin by Shyam Dheda, David A Vesey, Carmel Hawley, David W Johnson, Magid Fahim

“…The origin of this inflammation remains elusive and one putative cause is elevated levels of circulating bacterial endotoxin. …”
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Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study by Min Liu, Na Yin, Yuhang Zhu, Aili Du, Chunyuan Cai, Pengyuan Leng

“…The findings indicate that inhibitors targeting HMGCR may elevate the risk associated with the development of gout, while inhibitors targeting PCSK9 are likely to increase urate concentrations.…”
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Quelques observations sur l’alimentation des bonobos en semi-liberté au sanctuaire « Tasok » de Kinshasa by Paul N ’ Lemvo Budiongo

“…Le gain de poids le plus élevé est de 5 kg tandis que le moins élevé enregistré chez 3 individus est de 1 kg. …”
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High Serum Level of IL-17 in Patients with Chronic Obstructive Pulmonary Disease and the Alpha-1 Antitrypsin PiZ Allele by Margarita Y. Pervakova, Alexandra V. Mazing, Sergey V. Lapin, Olga Y. Tkachenko, Anna I. Budkova, Elena A. Surkova, Vladimir L. Emanuel, Olga N. Titova

“…The aim of this study was to determine whether homozygous or heterozygous PiZ allele carriage leads to elevated level of IL-17 and other proinflammatory cytokines in COPD patients. …”
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Construction of a prognostic prediction model for colorectal cancer based on 5-year clinical follow-up data by Boao Xiao, Min Yang, Yao Meng, Weimin Wang, Yuan Chen, Chenglong Yu, Longlong Bai, Lishun Xiao, Yansu Chen

“…SHAP analysis revealed that increased perioperative transfusion quantity, higher tumor AJCC stage, elevated carcinoembryonic antigen level, elevated carbohydrate antigen 19–9 (CA19-9) level, advanced age, and elevated carbohydrate antigen 125 (CA125) level were correlated with increased individual mortality risk. …”
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The Effect of Autologous Platelet Rich Plasma on Endometrial Receptivity: A Narrative Review by Milan Stefanović, Predrag Vukomanović, Ranko Kutlesic, Milan Trenkić, Vanja Dimitrov, Aleksa Stefanović, Vladimir Cvetanović

“…More than 50% of the evaluated studies resulted in enhanced endometrial thickness, increased endometrial receptivity, and an elevated pregnancy rate after the PRP application. …”
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Myelitis associated with glial fibrillary acidic protein IgG: characterization and comparison with aquaporin-4 IgG and myelin oligodendrocyte glycoprotein IgG myelitis by Yinyin Xie, Wanwan Zhang, Aoya Han, Wenlin Sun, Xinru Zhou, Yi Xie, Yunqing Ma, Yajun Lian, Cui Wang, Nanchang Xie

“…Cerebrospinal fluid (CSF) analysis showed markedly elevated leukocyte counts in 23 patients, elevated total protein in 28 patients, and decreased glucose levels in 9 patients. …”
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Dietary Fatty Acids and Predementia Syndromes by Vincenzo Solfrizzi, Vincenza Frisardi, Cristiano Capurso, Alessia D' Introno, Anna M. Colacicco, Gianluigi Vendemiale, Antonio Capurso, Francesco Panza

“…An increasing body of epidemiological evidence suggests that elevated saturated fatty acids (SFA) could have negative effects on age-related cognitive decline (ARCD). …”
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Enhancing thermoelectric properties of ScN films through twin domains by J. More-Chevalier, U.D. Wdowik, J. Martan, T. Baba, S. Cichoň, P. Levinský, D. Legut, E. de Prado, P. Hruška, J. Pokorný, J. Bulíř, C. Beltrami, T. Mori, M. Novotný, I. Gregora, L. Fekete, L. Volfová, J. Lančok

“…Therefore, structural twin domains in thin ScN film appear to be a simple and rather stable solution for the improvement of its thermoelectric properties at elevated temperatures.…”
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USP14 is crucial for proteostasis regulation and α-synuclein degradation in human SH-SY5Y dopaminergic cells by Vignesh Srinivasan, Rabah Soliymani, Larisa Ivanova, Ove Eriksson, Nina Peitsaro, Maciej Lalowski, Mati Karelson, Dan Lindholm

“…However, autophagy and coordinated lysosomal expression and regulation pathways were elevated in USP14 lacking cells with higher levels of the transcription factor TFEB. …”
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Oxidation state of bioavailable dissolved organic matter influences bacterioplankton respiration and growth efficiency by Brandon M. Stephens, Paolo Stincone, Daniel Petras, Chance J. English, Keri Opalk, Stephen Giovannoni, Craig A. Carlson

“…Across experiments, evidence emerged that nitrification and DOM partial oxidation, driven in part by bacterioplankton members of OM43, SAR92 and Rhodobacteraceae, can elevate BR relative to bacterioplankton consumption of plankton-derived carbon. …”
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Catatonic Dilemma in a 33-Year-Old Woman: A Discussion by Alexander Koch, Karin Reich, Jan Wielopolski, Marion Clepce, Marie Fischer, Johannes Kornhuber, Norbert Thuerauf

“…We report a case of catatonia with elevated CK, elevated temperature, and hypoferritinemia after abrupt discontinuation of clozapine in a patient with known proneness to catatonic symptoms. …”
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Effects of V on the dual-phase heterostructure FeCrNiVx medium-entropy alloys by Peng Sang, Ningning Liang, Lei Gu, Liangyu Chen, Yuan Lei, Zan Zhang, Yongsheng Li

“…The yield strength (σ0.2) and ultimate tensile strength (σUTS) of FeCrNiV0.3 MEA (V3) reach to 357 MPa and 855 MPa, respectively, which is elevated by 113.77 % and 94.32 % than those of V free FeCrNi MEA (V0). …”
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A Case of Atopic Myelitis with Cervical Cavernous Angioma by Miyuki Fukuda, Hiroaki Manabe, Nobuhiro Sasaki, Masayuki Kuroda, Minoru Hoshimaru, Shigeo Ueda

“…Atopic myelitis, a type of myelitis which appears in patients with elevated serum levels of immunoglobulin E (IgE), occurs more commonly in the cervical spinal cord, but this mechanism has not yet been elucidated. …”
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BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling by Chengzhu Zhao, Yoshiko Inada, Souta Motoike, Daisuke Kamiya, Kyosuke Hino, Makoto Ikeya

“…In this study, we evaluated the proliferation of MSCs obtained from FOP patient-derived induced pluripotent stem cells (FOP-iPSCs) to elucidate the mechanisms underlying flare-ups and found that bone morphogenetic protein (BMP)-9 mediated enhanced proliferation by abnormal activation of transforming growth factor (TGF)-β signaling pathway in MSCs from FOP-iPSCs. In FOP model mice, elevated BMP-9 levels correlated with elevated phosphorylation of SMAD2/3 and increased cellular proliferation in the affected tissues, while systemic BMP-9 neutralization and knockout mitigated flare-ups and HO. …”
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The hypertrophic cardiomyopathy-associated A331P actin variant enhances basal contractile activity and elicits resting muscle dysfunction by Matthew H. Doran, Michael J. Rynkiewicz, Evan Despond, Meera C. Viswanathan, Aditi Madan, Kripa Chitre, Axel J. Fenwick, Duncan Sousa, William Lehman, John F. Dawson, Anthony Cammarato

“…Such mutation-induced effects potentially elevate resting contractile activity among our models and may stimulate pathology in patients.…”
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