The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach by Irena Markova, Denisa Miklankova, Martina Hüttl, Petr Kacer, Jelena Skibova, Jan Kucera, Radislav Sedlacek, Tereza Kacerova, Ludmila Kazdova, Hana Malinska

“…Results. Chronically elevated levels of triglycerides in HHTg rats were associated with increased levels of NEFA during OGTT and over a period of 24 hours (+80%, P<0.01). …”
Get full text

Evaluation of potential productivity in coniferous forests by integrating field data and aerial laser scanning in Hidalgo, México by Rodrigo Ramos-Madrigal, Héctor M. de los Santos-Posadas, José René Valdez-Lazalde, Efraín Velasco-Bautista, Gregorio Ángeles-Pérez, Alma Delia Ortiz-Reyes

“…Material and methods: A total of 329 observations from five remeasurements in permanent forest inventory sampling units were used to generate site index curves and metrics derived from a 2013 LiDAR scan. LiDAR elevation metrics were statistically related to field-observed dominant height (DH). …”
Get full text

Influence of High-Frequency Repetitive Transcranial Magnetic Stimulation on Neurobehavioral and Electrophysiology in Patients with Disorders of Consciousness by Jian-Min Chen, Qing-Fa Chen, Zhi-Yong Wang, Yang-Jia Chen, Nan-Nan Zhang, Jian-Wen Xu, Jun Ni

“…Neural connectivity levels are affected by HF-rTMS and are significantly related to clinical responses in DOC patients with the presence of bilateral N20. The elevation of neural connectivity levels may lay a foundation for successful HF-rTMS treatment for DOC patients.…”
Get full text

How does gut microbiota affect the vaginitis axis? The mediating role of plasma metabolites by Mo Li, Qianyu Zhang, Tong Wu, Lanfang Ma, Dianxing Hu, Zixuan Yuan, Shixuan Wang, Aiyue Luo, Jinjin Zhang

“…On the contrary, the elevation of arachidonate/pyruvate ratio and reduction in palmitate/myristate ratio mediated the protective effects of Lachnospiraceae UCG-008 against vaginitis. …”
Get full text

Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice by Bing Li, Yu Cheng, Songyan Yu, Li Zang, Yaqi Yin, Jiejie Liu, Lin Zhang, Yiming Mu

“…UC-MSC infusions significantly ameliorated hyperglycaemia, attenuated the elevation of hepatic transaminases, and decreased lipid contents, including triglyceride, total cholesterol, and low-density lipoprotein cholesterol. …”
Get full text

Geo-behavioural predictors of diagnosed hypertension in Igbo Ora Area, Oyo State, Nigeria by Olalekan J. Taiwo, Joshua O. Akinyemi, Ayodeji Adebayo, Oluwafemi A. Popoola, Rufus O. Akinyemi, Onoja M. Akpa, Paul Olowoyo, Akinkunmi P. Okekunle, Ezinne O. Uvere, Omotolani Titilayo Ajala, Chukwuemeka Nwimo, Olayinka J. Adebajo, Adewale E. Ayodele, Ayodeji Salami, Oyedunni S. Arulogun, Olanrewaju Olaniyan, Richard W. Walker, Carolyn Jenkins, Bruce Ovbiagele, Mayowa Owolabi

“…Data on diagnosed hypertension patients and their behaviours were gathered during the ARISE project, complemented by geographical data (elevation, vegetation, road network, population density, and nighttime light exposure) from secondary sources. …”
Get full text

Randomized Clinical Trial of Intraocular Pressure-Lowering Medications on Preventing Spikes in Intraocular Pressure Following Intravitreal Anti-Vascular Endothelial Growth Factor I... by Piriya Soomsawasdi, Kulawan Rojananuangnit, Eakkachai Arayangkoon, Ratchada Chantiwas, Sureeporn Pengrungreungwong, Nontakorn Preawsampran, Natnaree Tinpowong, Rujira Samakhararaksakul, Kanokwan Katkingkaew, Natthapuch Seekhum, Wanwisa Sathim

“…Abstract Introduction Intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) agents are a primary management option for retinal diseases. Acute elevation of intraocular pressure (IOP) is a complication associated with these injections that should be considered. …”
Get full text

Wildfire indicators modeling for reserved forest of Vellore district (Tamil Nadu, India) by Yara EzAl Deen Sultan, Kanni Raj Arumugam Pillai, Archana Sharma

“…The most helpful fuel, activity, weather, and topography danger indexes are calculated using the Raster Calculator utility, Euclidean Distance tool, Kriging tool, and Digital Elevation Model, respectively. In the Vellore district, the calculated activity danger index ranges from 0 to 12,000, showing that the high risk emanates from human activities. …”
Get full text

Eminescu – poezia naşterii şi a stingerii (elemente de antropogonie eminesciană) by Carmina Cojocaru

“…The poet reached the highest degree of understanding life, the essence drawn out of a long line of other existing essences which, in our opinion, makes the most complex, shattering confession whose deep meaning is represented by human essence and becomes part of the Eminescu antropogonic foundation: comprehending life as „part of the whole” that would immediately lead to the complet understanding of death, and from here to the staggering elevation of the most stirring verse: “Nu credeam să-nvăţ a muri vreodată”. …”
Get full text

The role of sacubitril/valsartan in abnormal renal function patients combined with heart failure: a meta-analysis and systematic analysis by Xinyue Yang, Jingjing Jin, Meijuan Cheng, Jinsheng Xu, Yaling Bai

“…Moreover, sacubitril/valsartan prevented the serum creatinine elevation (OR: 0.81, 95%CI: 0.68–0.95), the eGFR decline (OR: 0.83, 95% CI: 0.73–0.95) and the development of end-stage renal disease in this population (OR:0.73, 95%CI:0.60–0.89). …”
Get full text

CtBP1 is essential for epigenetic silencing of μ-opioid receptor genes in the dorsal root ganglion in spinal nerve ligation-induced neuropathic pain by Cheng-Yuan Lai, Ming-Chun Hsieh, Chou-Ming Yeh, Tzer-Bin Lin, Dylan Chou, Hsueh-Hsiao Wang, Kuan-Hung Lin, Jen-Kun Cheng, Po-Sheng Yang, Hsien-Yu Peng

“…Immunohistochemistry revealed a significant elevation in CtBP1 levels specifically in NeuN-positive neuronal cells in the ipsilateral DRG following SNL. …”
Get full text

Long-term observation of the in vivo safety of a new design of phakic refractive lens by Yinjie Jiang, Xun Chen, Mingrui Cheng, I-Chun Lin, Boliang Li, Xinjie Zhu, Guanghan Xu, Huamao Miao, Xiaoying Wang, Xingtao Zhou

“…The capsular PC-PRL group showed anterior cortical proliferation and fibrosis. An IOP elevation was noted on the first postoperative day (18.8 to 37.9 mmHg). …”
Get full text

Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes by Alanna S. Hind, Reid A. Mitchell, Olivia N. Ferguson, Morgan Flynn, Satvir S. Dhillon, Karine Badra, Kathryn M. Milne, Danilo Iannetta, Michael S. Koehle, Jordan A. Guenette

“…Twenty participants (10M vs. 10F; V̇O2peak: 69.3 (8.8) vs. 50.7 (4.1) ml∙kg−1∙min−1) underwent a maximal incremental treadmill test (visit 1) and a time trial on a steep trail (~2.5 km, ~800 m elevation gain) in North Vancouver (visit 2). Pulmonary edema was evaluated using handheld lung ultrasound ~10–15 min post‐exercise and oxygen saturation (SpO2) was monitored using finger pulse oximetry. …”
Get full text

Preventive treatment with guarana powder (Paullinia cupana) mitigates acute paracetamol-induced hepatotoxicity by modulating oxidative stress by Clécia Dias Teixeira, Priscila Oliveira Barbosa, Wanderson Geraldo Lima, Gustavo Silveira Breguez, Miliane Martins de Andrade Fagundes, Daniela Caldeira Costa, Cintia Lopes de Brito Magalhães, Joana Ferreira Amaral, Melina Oliveira de Souza

“…Preventive treatment with guarana significantly mitigated this damage and prevented the serum elevation of ALT, AST, and ALP by 44 %, 29 %, and 24 %, respectively. …”
Get full text

Spatiotemporal evolution and driving force analysis of drought characteristics in the Yellow River Basin by Meiying Wang, Yangbo Chen, Jingyu Li, Yanjun Zhao

“…From 2000 to 2020, climate (q-value mean: 0.18) and DEM (q-value mean: 0.22) were the primary factors influencing drought variations, with climate interactions weakening and elevation interactions strengthening. This research provides crucial insights for effective water resource management and drought mitigation strategies in the Yellow River Basin.…”
Get full text

Integrate mathematical modeling for heat dynamics in two-phase casson fluid flow through renal tubes with variable wall properties by P. Deepalakshmi, Adil Darvesh, Hakim AL Garalleh, Manuel Sánchez-Chero, G. Shankar, E.P. Siva

“…Enhancement in particle volume fraction tends to a reduction in the rate of peristaltic pumping. An elevation in the Hall current parameter leads to a reduction in the growth of the bolus in the channel, as well as a drop in the velocity of the particle phase. …”
Get full text

Increasing vulnerability of an endemic Mediterranean-climate conifer to changing climate and fire regime by Frank W. Davis, Anne-Marie Parkinson, Max A. Moritz, Max A. Moritz, Isaac W. Park, Carla M. D’Antonio

“…Recently California’s MTE conifers have experienced elevated mortality, range shifts, and decreased abundance relative to broadleaf trees. …”
Get full text

Predicting the Global Distribution of <i>Nitraria</i> L. Under Climate Change Based on Optimized MaxEnt Modeling by Ke Lu, Mili Liu, Qi Feng, Wei Liu, Meng Zhu, Yizhong Duan

“…UV-B seasonality (UVB-2), UV-B of the lowest month (UVB-4), precipitation of the warmest quarter (bio18), the DEM (Digital Elevation Model), and annual precipitation (bio12) were the key variables affecting the distribution area of <i>Nitraria</i> L, with contributions of 54.4%, 11.1%, 8.3%, 7.4%, and 4.1%, respectively. …”
Get full text

Determining Dominant Factors of Vegetation Change with Machine Learning and Multisource Data in the Ganjiang River Basin, China by Zhiming Xia, Kaitao Liao, Liping Guo, Bin Wang, Hongsheng Huang, Xiulong Chen, Xiangmin Fang, Kuiling Zu, Zhijun Luo, Faxing Shen, Fusheng Chen

“…The most critical factors influencing the NDVI were forest and cropland ratio, followed by soil organic carbon content, elevation, cation exchange capacity, night-time light intensity, and CO₂ concentration. …”
Get full text

The efficacy and safety of a taxane-based chemotherapy regimen combined with a PD-1 inhibitor in HNSCC: a multicenter real-world study by Min Ouyang, Hanquan Sun, Xiaoyu Liu, Haijun Wu, Feilong Deng, Erdong Shen, Guozheng Peng, Hanbing Wu, Yinshan Zhao, Hui Xiong, Bin Liu, Shasha He, Ying Hu, Ping Liu

“…Regarding safety, during treatment anemia was observed in 97 patients, leukopenia in 64, neutropenia in 33, thrombocytopenia in 28, transaminase elevation in 46, hypothyroidism in 46 patients, and one patient stopped taking the medication due to a serious adverse reaction. …”
Get full text