HDAC Inhibition Modulates Cardiac PPARs and Fatty Acid Metabolism in Diabetic Cardiomyopathy by Ting-I Lee, Yu-Hsun Kao, Wen-Chin Tsai, Cheng-Chih Chung, Yao-Chang Chen, Yi-Jen Chen

“…Electrocardiography, echocardiography, and western blotting were used to evaluate the electrophysiological activity, cardiac structure, fatty acid metabolism, inflammation, and PPAR isoform expressions in the control and streptozotocin-nicotinamide-induced DM rats with or without MPT0E014. …”
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Which type of feedback—Positive or negative- reinforces decision recall? An EEG study by Michela Balconi, Michela Balconi, Laura Angioletti, Laura Angioletti, Roberta A. Allegretta, Roberta A. Allegretta

“…This study examines the impact of positive and negative feedback on recall of past decisions, focusing on behavioral performance and electrophysiological (EEG) responses. Participants completed a decision-making task involving 10 real-life scenarios, each followed by immediate positive or negative feedback. …”
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Neuroimaging features for cognitive fatigue and its recovery with VR intervention: An EEG microstates analysis by Jia-Cheng Han, Chi Zhang, Yan-Dong Cai, Yu-Ting Li, Yu-Xuan Shang, Zhu-Hong Chen, Guan Yang, Jia-Jie Song, Dan Su, Ke Bai, Jing-Ting Sun, Yu Liu, Na Liu, Ya Duan, Wen Wang

“…Microstate is an electrophysiological trait characteristic of cognitive fatigue and might be used to indicate the effect of VR intervention.…”
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Factors associated with the detection of atrial fibrillation in patients with embolic stroke of undetermined source by Jae-Han Bae, Jae-Chan Ryu, Sang Hee Ha, Min Soo Cho, Myung-Jin Cha, Jun Young Chang, Dong-Wha Kang, Sun U. Kwon, Jong S. Kim, Bum Joon Kim

“…All patients underwent transthoracic echocardiography and Holter to detect the source of embolism. Structural, electrophysiological markers of left atrial cardiopathy (i.e., left atrial enlargement [LAE], non-sustained tachycardia [NSAT]) as well as lesion patterns of ischemic stroke were examined. …”
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Abnormal dynamic features of cortical microstates for detecting early-stage Parkinson's disease by resting-state electroencephalography: Systematic analysis of the influence of eye... by G. Gimenez-Aparisi, E. Guijarro-Estelles, A. Chornet-Lurbe, D. Cerveró-Albert, Dongmei Hao, Guangfei Li, Y. Ye-Lin

“…Resting state electroencephalography (EEG) has proved useful in studying electrophysiological changes in neurodegenerative diseases. …”
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Electroacupuncture Increases the Hippocampal Synaptic Transmission Efficiency and Long-Term Plasticity to Improve Vascular Cognitive Impairment by Yaling Dai, Yuhao Zhang, Minguang Yang, Huawei Lin, Yulu Liu, Wenshan Xu, Yanyi Ding, Jing Tao, Weilin Liu

“…The Morris water maze (MWM) was used to assess cognitive function. Electrophysiological techniques were used to detect the field characteristics of the hippocampal CA3–CA1 circuit in each group of rats, including input-output (I/O), paired-pulse facilitation ratios (PPR), field excitatory postsynaptic potential (fEPSP), and excitatory postsynaptic current (EPSC). …”
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Patterns of colonic dismotility and visceral hypersensitivity at various clinical variants of irritable bowel syndrome by Ekaterina A. Bubnova, O. Yu. Fomenko, I. L. Khalif, V. V. Pavlenko

“…Conclusions. Basal electrophysiologic signs of motor and evacuatory function disorders at different IBS variants were not revealed. …”
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Five-Year Clinical Outcomes of Local versus General Anesthesia Deep Brain Stimulation for Parkinson’s Disease by Sheng-Tzung Tsai, Tsung-Ying Chen, Sheng-Huang Lin, Shin-Yuan Chen

“…Whether patients who received STN-DBS in GA could get the same benefit without compromising electrophysiological recording is debated. Methods. We compared five-year outcomes for different anesthetic methods (GA vs LA) during STN-DBS for PD. …”
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Heterozygous pathogenic STT3A variation leads to dominant congenital glycosylation disorders and functional validation in zebrafish by Linxue Meng, Zhixu Fang, Li Jiang, Yinglan Zheng, Siqi Hong, Yu Deng, Lingling Xie

“…Heterozygous knockdown zebrafish exhibit phenotypes similar to those of patients, including craniofacial dysmorphology (increased eye distance, increased Basihyal’s length, increased Ceratohyal’s angle), skeletal abnormalities (reduced number of mineralized bones), developmental delay (reduced adaptability under light‒dark stimuli suggesting abnormal locomotion, orientation, and social behavior), and electrophysiological abnormalities. Conclusion We report a proband with a dominant congenital glycosylation disorder caused by heterozygous pathogenic STT3A variation, which is a new inheritance pattern of STT3A. …”
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The effect of triple CFTR modulator therapy and azithromycin on ion channels and inflammation in cystic fibrosis by Suhad Bani Melhim, Lisa E.J. Douglas, James A. Reihill, Damian G. Downey, S. Lorraine Martin

“…As AZ has been reported to require CF transmembrane conductance regulator (CFTR) to be able to reduce interleukin (IL)-8 and given the emergence of highly effective CFTR “triple” modulator therapy (elexacaftor/tezacaftor/ivacaftor; ETI), the aim of this study was to investigate the effect of AZ and ETI, singly and in combination, on ion channel activity and to assess the potential anti-inflammatory effects. Methods Electrophysiological assessment of ETI and AZ was performed on three-dimensional cultures of primary CF human bronchial epithelial (HBE) cells using a Multi Trans-Epithelial Current Clamp. …”
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Glucocorticoid receptor gene (NR3C1) methylation, childhood maltreatment, multilevel reward responsiveness and depressive and anxiety symptoms: A neuroimaging epigenetic study by Yajing Xu, Shan Yang, Cong Cao

“…Conclusions: The current findings provide preliminary evidence for an Epi × E interaction underlying reward processing, highlight cross-level analyses of electrophysiological signals and advance knowledge of the biological foundation of stress-induced reward function and relevant symptoms. …”
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Neuropati Auditori by Sukri Rahman, Rossy Rosalinda

“…Purpose: To describe the audiological and electrophysiological features of auditory neuropathy in order to determine the effective treatment and intervention. …”
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Normative Values of Brainstem Auditory-Evoked Responses in Sheep by Katharina Suntinger, Adrian Dalbert, Lukas Prochazka, Milena Tegelkamp, Peter Kronen, Karina Klein, Christof Röösli, Alexander Huber, Flurin Pfiffner

“…<b>Background:</b> The brainstem auditory-evoked response (BAER) is an established electrophysiological measure of neural activity from the auditory nerve up to the brain stem. …”
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Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer by Leopold Harnoncourt, Martin Schmoll, Christopher Festin, Laurenz Pflaum, Markus Breuss, Johanna Klepetko, Dominik C. Dotzauer, Florian J. Jaklin, Udo Maierhofer, Philipp Tratnig-Frankl, Oskar C. Aszmann, Oskar C. Aszmann

“…In contrast, stained pseudounipolar cells in the dorsal root ganglia associated with the UN and MCN revealed afferent muscle innervations in Groups B and C.DiscussionThis novel SETS nerve transfer model enables isolated electrophysiological as well as histological evaluations of all nerve sections to determine the muscle innervation ratio exactly. …”
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Dopaminergic modulation of propofol-induced activation in VLPO neurons: the role of D1 receptors in sleep-promoting neural circuits by Kun Qian, Kun Qian, Yu Zhang, Yang Liu, Sisi Wu, Zikun Duan, Jianhao Liao, Jianhao Liao, Wei Luo, Mo Zhou, Xuejiao Dou, Xingkui Liu, Tian Yu

“…Propofol (PRO), a widely used intravenous anesthetic, modulates the activity of VLPO neurons, but the underlying mechanisms, particularly the role of dopaminergic receptors, remain unclear.ObjectiveThis study aimed to investigate the effects of PRO on NA (−) neurons in the VLPO and to determine the involvement of D1 and D2 dopaminergic receptors in mediating these effects.MethodsUsing in vitro patch-clamp techniques, we identified and characterized NA (−) and NA (+) neurons in the VLPO based on their morphological, pharmacological, and electrophysiological properties. We assessed the effects of PRO on spontaneous excitatory postsynaptic currents (sEPSCs) and inhibitory postsynaptic currents (sIPSCs) in NA (−) neurons, both in the presence and absence of dopaminergic receptor modulators.ResultsPRO significantly increased the firing frequency of NA (−) neurons while decreasing the firing frequency of NA (+) neurons. …”
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Biomimetic ECM nerve guidance conduit with dynamic 3D interconnected porous network and sustained IGF-1 delivery for enhanced peripheral nerve regeneration and immune modulation by Teng Wan, Qi-Cheng Li, Feng-Shi Zhang, Xiao-Meng Zhang, Na Han, Pei-Xun Zhang

“…Furthermore, observations at 12 weeks post-implantation revealed improvements in electrophysiological performance, alleviation of gastrocnemius muscle atrophy, increased peripheral nerve regeneration, and motor function restoration. …”
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Epicardially Placed Bioengineered Cardiomyocyte Xenograft in Immune-Competent Rat Model of Heart Failure by Ikeotunye Royal Chinyere, Pierce Bradley, Joshua Uhlorn, Joshua Eason, Saffie Mohran, Giuliana G. Repetti, Sherry Daugherty, Jen Watson Koevary, Steven Goldman, Jordan J. Lancaster

“…At the study endpoint, all cohorts underwent echocardiographic, hemodynamic, electrophysiologic, and histopathologic assessments. Results. …”
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Aging Alters Olfactory Bulb Network Oscillations and Connectivity: Relevance for Aging-Related Neurodegeneration Studies by A. Ahnaou, D. Rodriguez-Manrique, S. Embrechts, R. Biermans, N. V. Manyakov, S. A. Youssef, W. H. I. M. Drinkenburg

“…Taken together, the results highlight the sensitivity and therefore potential use of LFP quantitative network oscillations and connectivity at the OB level as objective electrophysiological markers that will help reveal specific dysfunctional circuits in aging-related neurodegeneration studies.…”
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Nerve Enlargement in Patients with INF2 Variants Causing Peripheral Neuropathy and Focal Segmental Glomerulosclerosis by Quynh Tran Thuy Huong, Linh Tran Nguyen Truc, Hiroko Ueda, Kenji Fukui, Koichiro Higasa, Yoshinori Sato, Shinichi Takeda, Motoshi Hattori, Hiroyasu Tsukaguchi

“…Both of them were electrophysiologically diagnosed with demyelinating neuropathy. …”
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Meridional anisotropy in contrast sensitivity and visual evoked potential in adults with high myopic astigmatism by Siu Sang Anthony Wu, Tsz Wing Leung, Tsz Wing Leung, Tsz Wing Leung

“…This discrepancy between psychophysical and electrophysiological measures may be related to the static versus flickering nature of the stimuli and warrants further investigation.…”
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