Self-concepts applied as a strategy to measure the level of acceptance of a Serious Game by Anthony Lins, Walter Franklin Marques Correia, Fábio Ferreira da Costa Campos, Marnix van Gisbergen, João Marcelo Xavier Natário Teixeira

“…A case study involved seven elderly participants. Despite some challenges in navigating the AR environment and cognitive tests, self-concept evaluations consistently demonstrated high user expectations and positive experiences with the digital artifact. …”
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A Rare Cause of Acquired Factor X Deficiency in an 87-Year-Old Female by Ayrton Bangolo, Trupti Waykole, Bilal Niazi, Chandini Sajja, Mahabuba Akhter, Bhavna Gupta, Sameh Elias

“…Here, we present a rare case of acquired isolated factor X deficiency in an elderly patient with immunoglobulin A (Ig A) monoclonal gammopathy of undetermined significance (MGUS). …”
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Research progress on the mechanisms of apolipoprotein E in Alzheimer’s disease by Jiayuan Li, Ting Liu, Shengxi Meng

“…Alzheimer’s disease (AD) is a degenerative disorder of the central nervous system that predominantly affects the elderly.The Apolipoprotein E (ApoE) gene is identified as the most significant genetic factor associated with AD.This article reviews current findings on the relationship between ApoE and AD, the impact of APOE gene polymorphisms on AD, the interaction between ApoE and other pathogenic factors, and the role of ApoE in AD.Additionally, it discusses the diagnosis and treatment of AD to enhance the understanding of its pathogenesis and to provide new perspectives for the prevention and management of the disease.…”
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Digital financial inclusion, population structure, and consumption upgrades: Evidence from China. by Qianwen Liu, Jianjie Zheng, Shihui Luo

“…Therefore, it is suggested that vigorously promote and develop digital financial inclusion, implement and improve the three-child policy, and expand the elderly consumer industry to better promote consumption upgrading.…”
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Hepatocellular Carcinoma in a 24-Year-Old Female with Beckwith–Wiedemann Syndrome: A Case Report and Review of the Literature by Carolyn G. Ahlers, Quoc-Huy Trinh, Martin Montenovo

“…Although HCC typically occurs in elderly adults or those with underlying liver disease, in this case, we show that HCC can occur in a young adult with BWS without any underlying liver disease.…”
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Epidemiology and Etiology of Young Stroke by Dayna Griffiths, Jonathan Sturm

“…Stroke in the young requires a different approach to investigation and management than stroke in the elderly given differences in the relative frequencies of possible underlying causes. …”
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Forgotten Elastic Band as an Unusual Cause of Limb Ulceration: Case Report and Review of the Literature by Keagan Werner-Gibbings, Liesl Ischia, Oleksandr Khoma, Robert Tang

“…We discuss a case of circumferential ulceration of the lower leg in a cognitively impaired elderly man with poor tissue integrity. Thorough clinical examination eventually determined the cause as being a circumferentially placed, forgotten elastic band causing ulceration via sustained tension around the limb. …”
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Musculoskeletal disorders and the work of the technicians and nursing assistants in homes for the aged by Janaína Bussola Montrezor Valença, Maria do Carmo Baracho de Alencar

“…Carried out a survey of the technicians and nursing assistants, through a questionnaire containing personal data (gender, age, education), work, and about musculoskeletal symptoms; instrumental Barthel Index with the elderly, and subsequently carrying out semi-structured interviews were recorded and transcribed for content analysis categories. …”
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Intestinal Obstruction by Meckel’s Diverticulum in a 92 Years Old Woman by Maryam Sarkardeh, Seyed Javad Davari Sani

“…Intestinal obstruction because of a large Meckel’s diverticulum in an elderly woman is rare and requires a high attention for diagnosis, and it is almost discovered by surgery.…”
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Effect of Combined Antihypertensive and Lipid-Lowering Therapies on Cognitive Function: A New Treatment Strategy? by Ze-Min Kuang

“…It is currently believed that hypertension and elevated blood cholesterol levels in middle-aged people may be related to cognitive impairment or dementia in the elderly. Some studies suggest that intensive antihypertensive or lipid-lowering therapies are better than standard antihypertensive or lipid-lowering therapy, yet further tests are needed to confirm their effects on cognitive function. …”
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Definition of Guideline-Based Metrics to Evaluate AAL Ecosystem’s Usability by Carlos Romeiro, Pedro Araújo

“…The elderly population growth has posed several challenges which the current healthcare systems are incapable of handling. …”
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Clinical Characteristics, Risk Factors, and Outcomes of Patients With Myocardial Injury due to Klebsiella pneumoniae Bloodstream Infections by Qingqing Chen, Panpan Xu, Zhihui Guan, Feizhen Song, Xinhua Luo, Xijiang Zhang, Chuming Zhang, Ronghai Lin, Cheng Zheng

“…Clinical physicians should be alert to the potential for myocardial injury in elderly critically ill patients, especially those who are on mechanical ventilation and have indwelling CVC, in the event of KP-BSI.…”
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Analysis of intention to purchase travel on the Web by German Gemar, Ismael P. Soler, Laura Melendez

“…While young consumers see purchasing tourismrelated services on the Internet as easy and cost-effective, the opposite results were obtained for the elderly. However, the perceived risks are considered important by most individuals. …”
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Global applications of the frailty index based on the deficit accumulation model by Xuemei Cai, Xiaodong Yao

“…Frailty is a prevalent geriatric syndrome associated with adverse health outcomes among the elderly. Currently, there is no uniform standardized tool for frailty assessment.The frailty index (FI), based on the concept of deficit accumulation, evaluates a broader range of health information and is recognized for its superior accuracy in predicting adverse clinical outcomes, such as mortality, hospital readmissions, and disability.This review focuses on the FI derivatives models, its application in various contexts, and its comparison with other assessment tools.The aim is to provide insights for utilizing the FI to better identify high-risk groups that are more susceptible to debilitating conditions.…”
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Future Therapies of Wet Age-Related Macular Degeneration by Makoto Ishikawa, Daisuke Jin, Yu Sawada, Sanae Abe, Takeshi Yoshitomi

“…Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population, and the prevalence of the disease increases exponentially with every decade after the age of 50 years. …”
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Targeting Chondrocyte Hypertrophy as Strategies for the Treatment of Osteoarthritis by Da-Long Dong, Guang-Zhen Jin

“…Osteoarthritis (OA) is a common joint disease characterized by pain and functional impairment, which severely impacts the quality of life of middle-aged and elderly individuals. During normal bone development, chondrocyte hypertrophy is a natural physiological process. …”
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Sporadic Pemphigus Foliaceus in a 3-Year-Old Vietnamese Girl: A Case Report and Literature Review by Trinh Thi Diem Nguyen, Trinh Ngoc To Chau, Phuong Thi Doan Vo, Hao Trong Nguyen

“…Sporadic pemphigus foliaceus is known to be more prevalent in middle-aged and elderly people and to be extremely rare in children. …”
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Echocardiographic Assessment of Ebstein's Anomaly in a 60-Year-Old Man by Elisabetta Palmerini, Duccio Federici, Alessia Del Pasqua, Sonia Bernazzali, Matteo Lisi, Mario Chiavarelli, Sergio Mondillo

“…We present an echocardiographic evaluation of an elderly man affected with Ebstein's anomaly. In the natural history of this congenital disease only 5% of patients survive beyond the fifth decade. …”
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Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma by Owen Ngalamika, Sody Munsaka

“…The different forms of KS including HIV-associated KS, iatrogenic (immunosuppression-related) KS, and classical KS in elderly males suggest that immune cell dysregulation is among the key components in promoting KS development in KSHV-infected individuals. …”
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Obstructive Nephropathy from Misplaced Suprapubic Catheter with Antegrade Migration into the Urethra by Alexander W. Lipinski, Jordan R. Pollock, Nelly Tan, Douglas Rappaport

“…Discussion: This case highlights the increased risk of suprapubic catheter misplacement and complications in elderly patients with neurogenic bladder and altered urinary anatomy, particularly after prostatectomy and artificial urethral sphincter placement. …”
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