Vision impairment and associated daily activity limitation: A systematic review and meta-analysis. by Masoud Rahmati, Lee Smith, Laurent Boyer, Guillaume Fond, Dong Keon Yon, Hayeon Lee, Tarnjit Sehmbi, Mapa Prabhath Piyasena, Shahina Pardhan

“…These findings highlight the need for targeted measures to raise public health awareness to provide rehabilitation and eye care examination strategies to reduce the risk of developing disabilities in adults and the elderly who have vision impairment.…”
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Compensatory increase in oxygen extraction fraction is associated with age-related cerebrovascular disease by John McFadden, Julian Matthews, Lauren Scott, Karl Herholz, Ben Dickie, Hamied Haroon, Oliver Sparasci, Saadat Ahmed, Natalia Kyrtata, Geoffrey J.M. Parker, Hedley C.A. Emsley, Joel Handley, Maélène Lohezic, Laura M. Parkes

“…We used a simultaneous PET-MRI protocol to measure OEF, CBF, CMRO2, and arterial transit time (ATT) in elderly people (n = 24, age 69.6 ± 5.3 years) with a range of vascular disease risk (QRisk 18.7 ± 10.8 %) and cognitive abilities (MoCA scores 26.7 ± 3.4) to determine if a) vascular disease risk (parameterised with QRisk2 score) is associated with altered CBF, ATT, OEF and CMRO2, b) if impaired blood supply and increasing transit times are associated with elevated OEF and c) if these physiological measures are associated with impaired cognition. …”
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Socio-economic assessment of drought impacts in Lesotho: implications for early action by Relebohile Agnes Mojaki, Makoala Vitalis Marake, Evan Easton-Calabria, Joalane Rethabile Marunye, Erin Coughlan de Perez

“…Overall, this paper conducted 48 community consultations where genderized focus group discussions (mixed elderly, mixed youth, middled aged men and women) and nine key informants (local authorities, schoolteachers, wisemen and women in the community) interviews were conducted. …”
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Is Intra-articular Platelet-rich Plasma Injection Safe and Effective in Osteoarthritis Knee? A Prospective Study: A Case Series by R Sahaya Jose, N Kattu Bava, M Syed Moosa

“…Background: Osteoarthritis (OA) of the knee is the most common slowly progressive chronic degenerative joint disease, characterized by varying degrees of loss of joint cartilage with local inflammation, usually affecting the elderly population. If oral drugs are ineffective, intra-articular injections (corticosteroids, viscous supplements, and blood-derived products) can be offered as another nonoperative modality. …”
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Early-life famine exposure may modify the association between long-term temperature variability and cardio-cerebrovascular diseases: a nationwide study by Yao Wu, BinBin Su, Junqing Xie, Bo Wen, Xiaolan Wu, Mengfan Wang, Yanhui Dong, Yi Song, Jun Ma

“…We used data from the fourth national urban and rural elderly population survey (2015). Participants were categorized into six groups based on their age at famine exposure (famine exposure under age 5, between ages 5 and 18, and during adulthood) and the severity (severely affected areas versus mildly affected areas) of the Great Chinese Famine (1959–1961) in their province of residence. …”
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Effects of population aging on quality of life and disease burden: a population-based study by Jun-Yan Xi, Bo-Heng Liang, Wang-Jian Zhang, Bo Yan, Hang Dong, Yuan-Yuan Chen, Xiao Lin, Jing Gu, Yuan-Tao Hao

“…Conclusions The disability effects among the elderly population hinder improvements in quality of life, while changes in age structure are the primary driver of disease burden accumulation. …”
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Prevalence of psychoactive substance use among acutely hospitalised patients in Oslo and Moscow: a cross-sectional, observational study by Stig Tore Bogstrand, Thomas Berg, Anners Lerdal, Danil Gamboa, Benedicte Jørgenrud, Evgeny A Bryun, Vigdis Vindenes, Evgenya A Koshkina, Aleksei V Nadezhdin, Saranda Kabashi, Elena J Tetenova, Anna Armika Tussilago Nyman, Alexey J Kolgashkin, Aleksei E Petukhov, Sergey N Perekhodov, Elena N Davydova, Gudmund Nordby

“…This is a cause for concern, particularly among the elderly, where physiological changes related to senescence increase the risk for adverse effects. …”
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Knowledge, Attitude, and Barriers Influencing Seasonal Influenza Vaccination Uptake by Mazin A. Barry, Khalid I. Aljammaz, Abdulaziz A. Alrashed

“…Influenza tends to cause epidemics with serious illness and death among high-risk groups such as children aged 5 years and younger, pregnant women, elderly ≥65 years of age, and with chronic medical conditions. …”
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Metabolic and functional factors associated with a change in resting metabolic rate among older adults with type 2 diabetes– results from the CEV-65 randomized trial by Assaf Buch, Roy Eldor, Ofer Kis, Arie Ben-Yehuda, Gizell Green, Yona Greenman, Sharon Barak

“…Conclusions: CRT, VegMedD, and empagliflozin showed similar effects on RMR in elderly with T2DM. Factors predicting changes in RMR are sleep hours, fat percentage, and leg strength, with those who increased/did not change their RMR presenting greater improvement in the aforementioned variables. …”
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Evaluating Fine-Scale Winter Nighttime PM_2.5 Concentrations and Population Exposure Using SDGSAT-1 Glimmer Imagery by Xuting Liu, Linlin Lu, Huadong Guo, Zilu Li, Xi Li, Muhammad Bilal

“…Notably, the CC UA exhibits the highest levels of exposure among children (<inline-formula><tex-math notation="LaTeX">$ \leq $</tex-math></inline-formula> 5 years) and the elderly (<inline-formula><tex-math notation="LaTeX">$ \geq $</tex-math></inline-formula> 65 years). …”
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Addressing inhaler technique challenges in cognitively impaired chronic obstructive pulmonary disease patients: the impact of customized training programs by Vaishnavi V Gaonkar, Vinay V Shanbhag, Shreya S Kajave, Mahek R Mattikop, Mandati Santhosh Reddy

“… Individuals with chronic obstructive pulmonary disease (COPD) and cognitive impairment (CI) often face difficulties accurately administering inhalers, which are essential for managing their respiratory condition. Many elderly individuals make major errors that prevent proper medicine administration. …”
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Landscape analysis of m6A modification reveals the dysfunction of bone metabolism in osteoporosis mice by Lifeng Zheng, Chao Lan, Xinyue Gao, An Zhu, Yaoqing Chen, Jinluan Lin, Sunjie Yan, Ximei Shen

“…Osteoporosis (OP) is a prevalent chronic bone metabolic disorder that affects the elderly population, leading to an increased susceptibility to bone fragility. …”
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Characterization and Detection Strategy Exploration in Cryptogenic Hepatocellular Carcinoma: Insights From a Super‐Aged Region in Japan by Takaaki Sugihara, Takakazu Nagahara, Takuya Kihara, Suguru Ikeda, Yoshiki Hoshino, Yukako Matsuki, Takuki Sakaguchi, Hiroki Kurumi, Takumi Onoyama, Tomoaki Takata, Tomomitsu Matono, Hajime Isomoto

“…Conclusion Patients with c‐HCC were predominantly elderly, without cirrhosis or diabetes, and exhibited minimal gender differences. …”
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Application of Nucleic Acid Reference Material for Rapid Detection of Cronobacter sakazakii (Cronobacter spp.) in Flammulina velutipes by Huandie Yang, Danyang Guo, Leilei Chen, Alexander Suvorov, Qingxin Zhou, Junhua Wang, Xiaofeng Gao, Jinyu Yang, Xiangyan Chen

“…It can cause meningitis, bacteremia, and necrotizing enterocolitis in infants and elderly people with low immunity. Therefore, the development of the rapid detection method for foodborne pathogen C. sakazakii is very important for food safety control. …”
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E_N_T_R_O_P_Y: Monocentric analysis of rectal cancer radio-chemotherapy treatment in patients of young age by E. Meldolesi, A. Nicolì, N. Dinapoli, G. Chiloiro, A. Romano, R. Menghi, R. Persiani, F. Pacelli, C. Coco, C. Ratto, S. Manfrida, L. Boldrini, B. Corvari, M.A. Gambacorta

“…For Both OS, DFS and MFS, the curves separated significantly at 55 years of age, with a prevalence of metastasis development in the older group. Conclusion: Elderly patients have a prevalence of advanced disease. …”
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Characteristics and real-world medication persistence of people living with HIV treated with DTG/3TC or BIC/FTC/TAF: a hospital claims database study in Japan by Rie Kanamori, Nozomi Aoki, Akio Kanazawa, Mayumi Yuda, Nao Makino, Emi Ohata, Nobuyuki Fukui, Hirotake Mori, Hirohide Yokokawa, Toshio Naito

“…There was no significant difference in medication persistence between the two cohorts (p = 0.91).ConclusionThis study showed that DTG/3TC was likely to be selected for elderly patients and those with chronic disease in real-world clinical practice, which seems in accordance with the treatment strategy recommended by guidelines. …”
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Study on the Therapeutic Effects of Bisdemethoxycurcumin on a Cerebral Amyloid Angiopathy Mouse Model Established via Chronic Treatment With Five Vascular Risk Factors by Shudong Lin, Guanghua Zhu, Juan Xie, Xuanwei Wen, Limin Deng, Sijing Li, Guozhi Liu, Feiyan Wang, Shuangxi Chen, Zijian Xiao

“…ABSTRACT Background and Purpose Cerebral amyloid angiopathy (CAA) is recognized as a major contributor to progressive cognitive decline and cerebral hemorrhages in the elderly population. Currently, there is a global shortage of safe and effective treatments for this condition. …”
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Disproportionate Distribution of HBV Genotypes A and D and the Recombinant Genotype D/E in the High and Low HBV Endemic Regions of Uganda: A Wake-Up Call for Regional Specific HBV... by Hussein Mukasa Kafeero, Dorothy Ndagire, Ponsiano Ocama, Charles Drago Kato, Eddie Wampande, Henry Kajumbula, David Kateete, Abdul Walusansa, Ali Kudamba, Kigozi Edgar, Fred Ashaba Katabazi, Maria Magdalene Namaganda, Jamilu E. Ssenku, Hakim Sendagire

“…Genotype D was significantly more prevalent in the high endemic region and among the elderly (p<0.05). Genotype D was significantly associated with elevated viral load and direct bilirubin (p<0.05). …”
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Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association by V. T. Ivashkin, N. D. Yushchuk, I. V. Mayev, Tatyana L Lapina, Ye. A. Poluektova, O. S. Shifrin, A. S. Tertychny, A. S. Trukhmanov, A. A. Sheptulin, Ye. K. Baranskaya, O. S. Lyashenko, K. V. Ivashkin

“…Risk factors of C. difficile-associated include antibacterial therapy, hospital admission, elderly age, comorbidity and immunosuppressive treatment. …”
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Characterization of Listeria monocytogenes strains isolated from soil under organic carrot farming by Maciej Nowak, Zbigniew Paluszak, Natalia Wiktorczyk-Kapischke, Katarzyna Grudlewska-Buda, Anna Budzyńska, Joanna Skonieczna-Kurpiel, Ewa Wałecka-Zacharska, Monika Huse-Kutowska, Krzysztof Skowron

“…This is an important aspect in organic farming, where products are chosen as a healthier option and consumed by children and the elderly.MethodsThe isolates were subjected to genetic similarity assessment (PFGE method), and the tested strains were evaluated for antibiotic susceptibility (disc-diffusion method), invasiveness (HT-29 line human colon cancer cell line), coaggregation with Salmonella Enteritidis, biofilm-forming ability and the effect of disinfectants on the biofilm.ResultsTwenty-seven isolates of L. monocytogenes were isolated from 250 soil samples, 10 of which were genetically different. 80% of the tested strains were sensitive to the tested antibiotics. …”
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