Heatstroke characteristics and meteorological conditions in Hefei, China: thresholds and driving factors by Xueliang Deng, Liang Zhao, Changchun Xiao, Rui Dai, Qianqian Xu, Yeqing Yao, Caimeng Liang, Lei Yao, Dongyan He

“…The reduced physical fitness of elderly people raised the risk of heatstroke more than other age groups in extremely high temperatures. …”
Get full text

Virtual primary care for people living with dementia in Canada: cross-sectional surveys of patients, care partners, and family physicians by Vladimir Khanassov, Deniz Cetin-Sahin, Sid Feldman, Saskia Sivananthan, Allan Grill, Isabelle Vedel

Get full text

Malignant transformation of proliferative Verrucous Leukoplakia—systematic review & meta-analysis by Khadijah Mohideen, Snehashish Ghosh, Chandrasekaran Krithika, Mutaz Ali-Hassan, Revant Chole, Safal Dhungel

“…Conclusions PVL, a rare variant of leukoplakia, poses a significant risk of cancer, emphasizing the need for vigilant monitoring and proactive treatment. It mainly affects elderly females without typical cancer risk factors. …”
Get full text

Coffee and tea consumption and dementia risk: The role of sex and vascular comorbidities by Kuan-Chu Hou, Yen-Ching Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Jeng-Min Chiou, Jen-Hau Chen

“…Methods: We included 278 elderly patients with Alzheimer's disease (AD) and 102 patients with vascular dementia (VaD) from three hospitals; controls (N = 468) were recruited during the same period. …”
Get full text

Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker by Ni M, Peng W, Wang X, Li J

“…Man Ni,1,2 Weilong Peng,1,2 Xiaoguang Wang,1,2 Jingui Li1,2 1School of Veterinary Medicine, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, People’s Republic of China; 2Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, 225009, People’s Republic of ChinaCorrespondence: Jingui Li, School of Veterinary Medicine, Yangzhou University, No. 48, Daxue North Road, Hanjiang District, Yangzhou City, Jiangsu, 225009, People’s Republic of China, Email jgli@yzu.edu.cnPurpose: An increasing proportion of the aging population has led to a rapid increase in the number of elderly patients with ulcerative colitis (UC). However, the molecular mechanisms by which aging causes UC remain unclear. …”
Get full text

Glycemic Management of Patients with Hospital Hyperglycemia: A Retrospective Cohort Study on Adults Admitted in the Non-ICU Wards by Zheng R, Zeng X, Shen R, Wang Y, Liu J, Zhang M

“…However, control among the elderly remains poor, with a notably high risk of hypoglycemia during nighttime and bedtime periods.Keywords: hyperglycemia, glycemic management, glucose monitoring, hospitalization, diabetes mellitus…”
Get full text

Pseudoprogression in CAR-T cell therapy for solid tumor: Case report by Xuan Zhao, Xuan Zhao, Yanfen Liu, Yanfen Liu, Guohui Qin, Guohui Qin, Yan Ge, Qinglong Li, Xinfeng Chen, Xinfeng Chen, Ximei Tian, Yong Yu, Jiangtao Ren, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang

“…We reported the pseudoprogression in an elderly patient with advanced gastric cancer after chimeric antigen receptor (CAR)-T cell therapy. …”
Get full text

Assessment of heart rate deceleration capacity, heart rate deceleration runs, heart rate acceleration capacity, and lipoprotein-related phospholipase A2 as predictors in individual... by Yaping Wang, Mingyan Liu, Yaping Liu, Xiaowei Tang, Xiangming Tang

“…For this purpose, we measured and analyzed the predictive value of heart rate deceleration capacity (DC), heart rate deceleration runs (DRs), heart rate acceleration capacity (AC) along with the plasma levels of lipoprotein-associated phospholipase A2 (Lp-PLA2).MethodsWe compared 83 dementia cases including 41 vascular dementia (VD), 42 Alzheimer’s disease (AD) patients with 42 elderly health controls. The Mini-Mental State Examination (MMSE) scores, DC, DRs, AC, and Lp-PLA2 levels were comprehensively evaluated.ResultsOur studies showed that DC and DRs in VD and AD groups were significantly lower than those in controls, while AC values were significantly higher. …”
Get full text

Higher Physical Activity is Associated with Reduced Lower Urinary Tract Symptoms in Korean Men by Seo Eun Hwang, Jae Moon Yun, Su Hwan Cho, Kyungha Min, Ji Young Kim, Hyuktae Kwon, Jin Ho Park

“…Purpose: Identifying and managing risk factors for lower urinary tract symptoms (LUTS) is crucial because it impacts the quality of life of elderly individuals. Lifestyle factors, including physical activity (PA), and their relationship with LUTS have not been well studied. …”

Correlation and predictive value of novel anthropometric indicators with adult sarcopenia and sarcopenia obesity by Xue Wu, Ziang Chen, Yuanhui Zhao, Hong Ren

“…Sarcopenia and sarcopenic obesity are commonly observed in individuals within the middle-aged and elderly demographics. The prevalence of these conditions is higher among middle-aged men of a given age when contrasted with women at the age of 40. …”
Get full text

Renal Transplants from Older Deceased Donors: Use of Preimplantation Biopsy and Differential Allocation to Dual or Single Kidney Transplant according to Histological Score Has No A... by Costanza Casati, Valeriana Giuseppina Colombo, Marialuisa Perrino, Ornella Marina Rossetti, Marialuisa Querques, Alessandro Giacomoni, Agnese Binaggia, Giacomo Colussi

“…Background. Grafts from elderly donors (ECD) are increasingly allocated to single (SKT) or dual (DKT) kidney transplantation according to biopsy score. …”
Get full text

Systemic therapy a risk factor for glaucoma development and progression by A.M. Getmanova, A.Yu. Brezhnev, A.V. Kuroyedov, V.I. Baranov, A.S. Dvornikov

“…Glaucoma treatment, in particular, in elderly patients, is often accompanied by systemic comorbidities and the intake of multiple systemic drugs. …”
Get full text

Socioeconomic inequality in hypertension and its determinants in people over 60 years in Fasa, southern Iran: a Blinder-Oaxaca decomposition by Reza Tabrizi, Reza Pakzad, Maryam Akbari, Azizallah Dehghan, Mozhan Abdollahi, Sina Bazmi, Sina Kardeh, Yaser Sarikhani

“…Results The research indicated that elderly individuals with a higher risk of developing HTN were notably linked to factors such as socioeconomic status, education level, a history of coronary artery disease, employment status, smoking habits, body mass index (BMI), waist‒hip ratio (WHR), and physical activity (p < 0.05). …”
Get full text

The Propensity for Inducing Atrial Fibrillation: A Comparative Study on Old versus Young Rabbits by Hongliang Li, Benjamin J. Scherlag, David C. Kem, Caitlin Zillner, Shailesh Male, Sorkko Thirunavukkarasu, Xiaohua Shen, Alexandria Benbrook, Jan V. Pitha, Ralph Lazzara, Xichun Yu

“…It is well established that atrial fibrillation (AF) is far more common in elderly humans. Autonomic activation is thought to be an operative mechanism for AF propensity. …”
Get full text

Ozone exposure and cardiovascular disease: A narrative review of epidemiology evidence and underlying mechanisms by Qiaoyi Hua, Xin Meng, Jicheng Gong, Xinghua Qiu, Jing Shang, Tao Xue, Tong Zhu

“…Certain populations display heightened vulnerability to these effects, particularly children, the elderly, obese individuals, and those with pre-existing conditions. …”
Get full text

Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation by Hermine Counil, Rummenigge Oliveira Silva, Jean‐Michel Rabanel, Charlotte Zaouter, Mohamed Haddad, Mohamed Raâfet Ben Khedher, Davide Brambilla, Tamas Fülöp, Shunmoogum A. Patten, Charles Ramassamy

“…The objective of our study was to compare the passage of pEVs from adults, cognitively healthy elderly, and AD patients through the blood‐brain barrier (BBB), to evaluate their uptake in the brain and to assess their impact on the microglia activity using in vitro and in vivo models. …”
Get full text

The association between frailty and falls among individuals aged 60 years and older residing in community settings and experiencing hip fractures in China: a cross-sectional study by Lan Jiang, Shulong Ding, Juxia Wang

“…Objectives Previous studies have established a correlation between frailty and an increased risk of falls among middle-aged and elderly individuals within community settings. The frailty status of hospitalized and community-dwelling adults aged 60 or older with hip fractures is poorly investigated. …”
Get full text

Multicenter Surveillance of Pseudomonas aeruginosa Isolates From Blood: Clinical Distribution Characteristics and Antibiotic Resistance Trends in Hebei Province, China (2016&ndash;... by Qiang C, Liu X, Qin P, Wen H, Li Z, Yang J, Niu Y, Wang W, Ouyang Z, Zhao M, Li J, Zhang Y, Zhao J

“…Resistance rates were notably higher in pediatric and intensive care medicine, particularly in neonatal patients, where resistance to antimicrobial drugs, such as piperacillin/tazobactam, gentamicin, ciprofloxacin, and levofloxacin, exceeded 75%.Conclusion: The main isolates of P. aeruginosa were from elderly and intensive care patients, with a male predominance. …”
Get full text

Using CT imaging to identify sarcopenia as a risk factor for severe falls in older adults by Nadja Fries, Angeliki Kotti, Mischa Woisetschläger, Anna Spångeus

“…Conclusions These results underscore the importance of addressing sarcopenia and related risk factors, including malnutrition, in the management and prevention of severe falls in the elderly population. Body composition analyzed in CT-scans could add value in this risk assessment. …”
Get full text

Vitamin D Status in Central Europe by Pawel Pludowski, William B. Grant, Harjit Pal Bhattoa, Milan Bayer, Vladyslav Povoroznyuk, Ema Rudenka, Heorhi Ramanau, Szabolcs Varbiro, Alena Rudenka, Elzbieta Karczmarewicz, Roman Lorenc, Justyna Czech-Kowalska, Jerzy Konstantynowicz

“…The longitudinal study reported wintertime 25(OH)D values close to 21–23 ng/mL for all studied age groups, with a significant increase of 25(OH)D in August reaching 42 ng/mL for those aged 0–9 years, but only 21 ng/mL for the elderly aged 80–89 years. The decrease in 25(OH)D with respect to age was attributed to decreased time spent in the sun and decreased vitamin D production efficiency. …”
Get full text