Clinical characteristics and mortality risk factors among trauma patients by age groups at a single center in Korea over 7 years: a retrospective study by Jonghee Han, Su Young Yoon, Junepill Seok, Jin Young Lee, Jin Suk Lee, Jin Bong Ye, Younghoon Sul, Seheon Kim, Hong Rye Kim

“…The high mortality rate of elderly patients suggests the need for different treatment approaches for trauma patients according to age. …”
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Corneal endothelial dysfunction: etiology, pathogenesis, and current treatment approaches by S.V. Trufanov, E.P. Salovarova

“…Bullous keratopathy is characterized by progressive corneal edema and occurs mainly in elderly population. The major goals of the treatment are to minimize persistent corneal edema and to improve associated discomfort and poor vision. …”
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Impact of urbanisation on the gaps of hypertension prevalence, awareness and treatment among older age in China: a cross-sectional study by Qiutong Yu, Genyong Zuo

“…Objectives To examine the impact of urbanisation on the prevalence, awareness and treatment of hypertension among elderly in China.Design This cross-sectional study used data from the most recent nationally representative Chinese Longitudinal Healthy Longevity Survey, 2018.Setting People in urban and rural communities from 500 sample areas in 22 Chinese provinces.Participants After exclusion, this study surveyed 9859 participants in the final analysis.Primary and secondary outcome measures The main dependent variables were prevalence, awareness and treatment of hypertension defined as (1) systolic blood pressure (BP)≥140 mm Hg, diastolic BP≥90 mm Hg or (2) taking antihypertensive drugs. …”
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Short-term effects of empagliflozin on preventing contrast induced acute kidney injury in patients undergoing percutaneous coronary intervention, a randomised trial by Zeinab Sadat Hosseini, Mohammad Javad Jamili, Behzad Ensan, Ghazaleh Donyadideh, Bahram Shahri, Hamid Eshraghi, Susan Darroudi, Mohsen Moohebati

“…These benefits were observed across various age groups, particularly in middle-aged and elderly, and those with varying renal function levels.…”
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Gender and age characteristics and atrial fibrillation during long-term telemonitoring of the ECG by V.M. Bogomaz, I.O. Berdnyk, L.I. Lysa

“…In total, AF was diagnosed in 7.93 % of patients, in particular, women and men were 6.51 % and 9.54 % respectively (p > 0.05). In elderly patients, AF was diagnosed statistically significantly more often than in middle-aged patients (18.5 and 3.6 %, respectively, p ˂ 0.001). …”
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Natremia Significantly Influences the Clinical Outcomes in Patients with Severe Traumatic Brain Injury by Bharti Sharma, Winston Jiang, Munirah M. Hasan, George Agriantonis, Navin D. Bhatia, Zahra Shafaee, Kate Twelker, Jennifer Whittington

“…<b>Result</b>: Variations in hospital (H) admission SLs were statistically significant across four age ranges (pediatric, young adult, older adults, and elderly). Intensive care unit (ICU) admission, H discharge, and death also showed significance. …”
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Time to recovery of COVID-19 patients and its predictors: a retrospective cohort study in HUCSH, Sidama, Ethiopia by Ali B. Anteneh, Zeytu Gashaw Asfaw

“…Conclusions Recent studies found that about 95% of COVID-19 patients recover within 30 days, with a median of 12 days. Severe cases, elderly, and those with comorbidities may take longer to recover. …”
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Expression Profiling and Functional Implications of a Set of Zinc Finger Proteins, ZNF423, ZNF470, ZNF521, and ZNF780B, in Primary Osteoarthritic Articular Chondrocytes by Maria Mesuraca, Olimpio Galasso, Leonardo Guido, Emanuela Chiarella, Stefania Scicchitano, Renaud Vatrinet, Giovanni Morrone, Heather M. Bond, Giorgio Gasparini

“…This analysis highlighted a significantly lower expression of the transcript encoding ZNF423 in chondrocytes from OA, particularly in elderly patients. Interestingly, this decrease was mirrored by the similarly reduced expression of PPARγ, a known target of ZNF423 with anti-inflammatory and chondroprotective properties. …”
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Association of Diabetes Mellitus with Carotid Artery Stenosis Undergoing Coronary Artery Bypass Graft in Bangladesh: A Prospective Cross-Sectional Study by Chowdhury MAT, Joshi D, Magdum M, Adhikary D, Saklayen S, Alauddin M, Ranjan R, Adhikary AB

“…The Pearson correlation coefficient shows a significant positive association between higher glycated haemoglobin levels and > 50% CAS (correlation coefficient 0.270; p = 0.007).Conclusion: We found higher HbA1c had a significant positive correlation with > 50% CAS in diabetic patients undergoing elective CABG, recommending preoperative carotid screening, especially elderly individuals.Keywords: carotid artery stenosis, coronary artery disease, diabetes mellitus, duplex scan…”
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Assessment of Technology Readiness in Norwegian Older Adults With Long-Term Health Conditions Receiving Home Care Services: Cross-Sectional Questionnaire Study by Sverre Bergh, Jūratė Šaltytė Benth, Lisbeth Dyrendal Høgset, Britt Rydjord, Lars Kayser

“…ConclusionsThe technology readiness level varied in our cohort of Norwegian participants receiving home care. Not all elderly people have the eHealth literacy to fully benefit from digital health services. …”
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Application of deep learning model based on unenhanced chest CT for opportunistic screening of osteoporosis: a multicenter retrospective cohort study by Chengbin Huang, Dengying Wu, Bingzhang Wang, Chenxuan Hong, Jiasen Hu, Zijian Yan, Jianpeng Chen, Yaping Jin, Yingze Zhang

“…Abstract Introduction A large number of middle-aged and elderly patients have an insufficient understanding of osteoporosis and its harm. …”
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Impact of MMP2 rs243865 and MMP3 rs3025058 Polymorphisms on Clinical Findings in Alzheimer’s Disease Patients by Vladimira Durmanova, Juraj Javor, Zuzana Parnicka, Gabriel Minarik, Agata Ocenasova, Barbora Vaseckova, Veronika Reznakova, Maria Kralova, Tomas Hromadka, Ivana Shawkatova

“…Alzheimer’s disease (AD) is a chronic neurodegenerative disease of the central nervous system with higher prevalence in elderly people. Despite numerous research studies, the etiopathogenesis of AD remains unclear. …”
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OCT Biomarkers in Neovascular Age-Related Macular Degeneration: A Narrative Review by Cristian Metrangolo, Simone Donati, Marco Mazzola, Liviana Fontanel, Walter Messina, Giulia D’alterio, Marisa Rubino, Paolo Radice, Elias Premi, Claudio Azzolini

“…Age-related macular degeneration (AMD) is the leading cause of legal blindness in elderly people. Neovascular AMD (nAMD) is responsible for the majority of cases of severe visual loss in eyes with AMD. …”
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Parent’s Perspective on Continuity of Care in the Maternity Care and Child Health Services Continuum: A Qualitative Systematic Review by Anne C. M. Hermans, Silke Boertien, Lauri M. M. van den Berg, Ank de Jonge, Danielle E. M. C. Jansen, Arie Franx, Jacoba van der Kooy, Marlou L. A. de Kroon

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Investigating the link between frailty and outcomes in geriatric patients with isolated rib fractures by Yang Cao, Shahin Mohseni, Babak Sarani, Frank Hildebrand, Ahmad Mohammad Ismail, Maximilian Peter Forssten, Marcelo AF Ribeiro

“…Background Studies have shown an increased risk of morbidity in elderly patients suffering rib fractures from blunt trauma. …”
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Mortality trends of traumatic brain injuries in the adult population of the United States: a CDC WONDER analysis from 1999 to 2020 by Muhammad Hamza Dawood, Yusra Fazli, Sejal Lund, Shurjeel Uddin Qazi, Rija Tahir, Areehah Zafar Masood, Aiman Azam Qureshi, Saleha Safdar, Heraa Zaheer, Muhammad TayyabMuzaffar Chaychi

“…Accounting for a substantial proportion of injury-related deaths and disabilities, TBI impacts a wide demographic, with particularly high incidence rates among young and elderly populations. Despite earlier declines, recent years have seen an uptick in TBI-related fatalities. …”
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Polymorphic variants of the <i>hOGG1, APEX1, XPD, SOD2</i>, and <i>CAT</i> genes involved in DNA repair processes and antioxidant defense and their association with breast cancer r... by А. А. Timofeeva, V. I. Minina, A. V. Torgunakova, О. А. Soboleva, R. А. Тitov, Ya. А. Zakharova, M. L. Bakanova, А. N. Glushkov

“….= 0.011; OR = 1.39; CI 95 %: 1.07–1.81; Padj = 0.013 и OR = 1.70; CI 95 %: 1.19–2.43; Padj = 0.004, respectively). In the group of elderly women (aged 60–74 years), an association of the CAT gene polymorphism with the risk of developing luminal B subtype of breast cancer was found in a log-additive inheritance model (OR = 1.87; 95 % CI: 1.22–2.85; Padj = 0.0024). …”
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Randomised controlled trial comparing intraoperative cell salvage and autotransfusion with standard care in the treatment of hip fractures: a protocol for the WHITE 9 study by Mike Murphy, Nicholas Parsons, James Mason, Juul Achten, Duncan Appelbe, Edward Dickenson, Damian Griffin, Katy Mironov, Matthew Wyse, Amrita Athwal, Xavier Luke Griffin, Heather O'Connor

“…Introduction People who sustain a hip fracture are typically elderly, frail and require urgent surgery. Hip fracture and the urgent surgery is associated with acute blood loss, compounding patients’ pre-existing comorbidities including anaemia. …”
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Potential biomarkers for cerebral small vessel disease with cognitive impairment: a systematic review and meta-analysis by Libin Liao, Weiquan Huang, Rongchao Ma, Xuan He, Xuan He, Moxi Su, Dujuan Sha, Dujuan Sha, Dujuan Sha

“…CSVD-related cognitive impairment (CSVD-CI) affects more and more elderly people, resulting in economic losses and burdens on families and society. …”
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Clinical characteristics, therapeutics, and treatment outcomes of adult patients with anti-melanoma differentiation-associated gene 5 dermatomyositis: A single-center experience fr... by Shivraj Padiyar, Aswin M Nair, Bijesh Yadav, Prathyusha Manikuppam, Jha Avanish, Abhilasha Arvind Manwatkar, John Mathew

“…Conclusions: Anti-MDA5 DM represents a distinct and unique subset of IIM with characteristic clinical manifestations. Elderly age is a poor prognostic factor of mortality.…”
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