Deep-Sea-Derived Isobisvertinol Targets TLR4 to Exhibit Neuroprotective Activity via Anti-Inflammatory and Ferroptosis-Inhibitory Effects by Zi-Han Xu, Ming-Min Xie, Chun-Lan Xie, Xian-Wen Yang, Jun-Song Wang

“…Neuroinflammation and neuronal cell death are leading causes of death in the elderly and underlie various neurodegenerative diseases. …”
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Epidemiological and Clinical Aspects of Ulcerative Colitis in Mosul city, Iraq by Muhammed Babakir-Mina

“…The results showed that 49.0% of patients was males and 51.0% was female; the mean age was 46.36 years old. Elderly stage (> 45 years of age) makes the highest proportion of the patients 99 (49.5%). …”
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China’s national continuing medical education program for general practitioners: a cross-sectional survey (2016–2023) by Conglei You, Lingling Wang, Jian Zhang, Mi Yao

“…Content-based CME evaluations revealed that the teaching focus is the diagnosis, treatment, and primary care management of elderly patients and chronic diseases such as diabetes and hypertension. …”
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Onset of age, site and respiratory symptoms are strongly associated with respiratory decline in sporadic amyotrophic lateral sclerosis: a long-term longitudinal study by Gen Sobue, Shin-ichi Terao, Yasunobu Nosaki, Atsunori Murao, Ryota Torii, Nanayo Ogawa, Naofumi Miura, Yousuke Sasaki

“…Multivariate analysis revealed that age at onset, site of onset, Onset-Rp and %VC decline rate significantly influenced Onset-REP duration. Elderly patients had a significantly shorter Onset-REP duration. …”
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Persistent hepatocyte secretory failure in lopinavir/ritonavir related to drug-induced liver injury: a case report by Yue Sun, Ran Wang, Cai'e Wang, Xiaodong Shao, Xiaojie Zheng, Hui Li, Yingkai Chi, Baocheng Deng, Yiling Li, Shenghao Jin, Xingshun Qi

“…In this paper, we reported an elderly female patient with drug-induced liver injury secondary to lopinavir/ritonavir, which was evaluated for their causality using the updated Roussel Uclaf Causality Assessment Method (RUCAM) of 2016. …”
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Identification of Plasma Proteins Associated with Alzheimer's Disease Using Feature Selection Techniques and Machine Learning Algorithms by Zakaria Mokadem, Mohamed Djerioui, Bilal Attallah, Youcef Brik

“… Alzheimer’s disease (AD) is a chronic, progressive neurodegenerative disorder that typically affects elderly individuals. Detecting Alzheimer’s using plasma proteins is a critical step toward improving treatment results for this disease. …”
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Self-reported illnesses in Thatta: Evidence from a rural and underdeveloped district in Sindh province, Pakistan. by Muhammad Ashar Malik, Rahat Batool, Muhammad Ahmed, Imran Naeem Abbasi, Zafar Ahmed Fatmi, Sarah Saleem, Sameen Siddiqui

“…Children aged < 1 year (0.80) and elderly >65 years (0.78) were more likely to have comorbidities.…”
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Safety and Risk Factors of Needle Thoracentesis Decompression in Tension Pneumothorax in Patients over 75 Years Old by Yanhu Wang, Lei Wang, Cheng Chen, Yifan Que, Yinyi Li, Jiang Luo, Ming Yin, Miao Lv, Guogang Xu

“…There are very few professional recommendations or guidelines on the needle thoracentesis decompression (NTD) for the tension pneumothorax in the elderly. This study aimed to investigate the safety and risk factors of tension pneumothorax NTD in patients over 75 years old based on CT evaluation of the chest wall thickness (CWT). …”
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THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY by T.A. Trybrat, Yu.M Kazakov, O.O. Honcharova, S.V Shut, V.D. Sakevich

“…To date, there is a decrease in the number of cases per day, but there is a variety in the course of the disease depending on sex, and the most vulnerable are elderly patients with comorbid pathology, therefore, the study of its features determines the relevance of this work. …”
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The COVID-19 pandemic and its impact on mental health. Causes and consequences - an overview by Michał Jakub Cioch, Urszula Kaczmarska, Aleksandra Woźniak, Julia Nowak, Kamil Hermanowicz, Katarzyna Doman, Agnieszka Najdek, Daria Oleksy, Marcin Mycyk, Dawid Komada

“…Special attention was paid to vulnerable groups (e.g., children and the elderly, etc.) and how changes in the pandemic (e.g., social isolation) affected mental health. …”
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Age and Sex Variation in the Duration of Action and Corneal Touch Threshold (CTT) following Instillation of 0.5% Topical Ophthalmic Proparacaine and Tetracaine Hydrochlorides by Samuel Kyei, Nana Yaw Abaka Dadzie, Ebenezer Zaabaar, Kwasi Antwi Asamoah Dwomoh, Kofi Asiedu

“…The total duration of the effect of both solutions decreased with increasing age; however, elderly participants had the longest duration (5 minutes) of the maximal effect (minimum CTT) of the two ophthalmic preparations. …”
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The Effects of Chlormadinone Acetate on Lower Urinary Tract Symptoms and Erectile Functions of Patients with Benign Prostatic Hyperplasia: A Prospective Multicenter Clinical Study by Kiyohide Fujimoto, Yoshihiko Hirao, Yasuo Ohashi, Yasuhiro Shibata, Kohzo Fuji, Hidenori Tsuji, Katsuhito Miyazawa, Mikinobu Ohtani, Ryoji Furuya, Eitetsu Boku

“…Our results suggest that CMA is safe and beneficial, especially for elderly patients with LUTS associated with BPH.…”
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Development and application of a dietary program to reduce sugar intake using a living lab approach in Korea: an intervention study by Jung-Hyun Kim, Min Sook Kyung, Seul Ki Choi

“…Participants were recruited from community organizations, including a children’s food service management center, elementary to high schools, a university, a family center, a community health center, and an elderly welfare center. The dietary program was conducted in two phases; start and next levels. …”
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Impact of handgrip strength on cardiovascular, cancer and all-cause mortality in the Korean longitudinal study of ageing by Gyu Ri Kim, Jiyu Sun, Minkyung Han, Sohee Park, Chung Mo Nam

“…However, there were no significant differences in the rates of cancer-related death, with HR of 1.29 (95% CI 0.92 to 1.81 [lowest vs highest tertile; p trend=0.21]).Conclusion These results demonstrate that lower handgrip strength is an independent predictor of mortality among a population-based sample of Korean elderly; highlighting the importance of interventions targeted at enhancing muscle strength for improvements in survival at older ages.…”
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Xanthone and Flavone Derivatives as Dual Agents with Acetylcholinesterase Inhibition and Antioxidant Activity as Potential Anti-Alzheimer Agents by Inês Cruz, Ploenthip Puthongking, Sara Cravo, Andreia Palmeira, Honorina Cidade, Madalena Pinto, Emília Sousa

“…Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder that is associated with the elderly. The current therapy that is used to treat AD is based mainly on the administration of acetylcholinesterase (AChE) inhibitors. …”
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Trend in burden of rheumatoid arthritis in China from 1990 to 2021 by WEN Jiaxin，JIANG Junpeng，FENG Min，SHEN Xiaochen，LI Xiaoyin

“…Higher disease burden of RA was seen in females and the elderly.…”
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Strategic Planning of Public Spaces in Order to Promote and Benefit from Social Interactions, Case Study: District 10 of Tehran Municipality by samaneh jalilisadrabad, somayeh jalilisadrabad

“…Moreover, creating favorable conditions for the presence of children and the elderly would lead to increased supervision and social security.  …”
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Interdigital and Plantar Foot Infections: A Retrospective Analysis of Molecularly Diagnosed Specimens in the United States and a Literature Review by Aditya K. Gupta, Tong Wang, Sara A. Lincoln, Wayne L. Bakotic

“…An analysis of patient characteristics showed male patients exhibiting higher likelihoods for dermatophyte, <i>C. minutissimum</i>, <i>Pseudomonas</i> and <i>S. aureus</i> detections. The elderly were disproportionately infected with <i>Candida</i>. …”
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Single-cell transcriptome atlas of male mouse pituitary across postnatal life highlighting its stem cell landscape by Silke De Vriendt, Emma Laporte, Berkehür Abaylı, Julie Hoekx, Florian Hermans, Diether Lambrechts, Hugo Vankelecom

“…Our investigation substantiated changes in stem cell dynamics during aging, reinforcing the inflammatory/immune nature in elderly pituitary and stem cells. Finally, we show translatability of mouse atlas-based findings to humans, particularly regarding aging-associated profile. …”
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The organizational challenges of municipal call centers as a health service in Norway-a multiple case study by Linda Grøndal-Eeles, Janne Dugstad, Hilde Eide, Etty Nilsen

“…Abstract Background To maintain sustainability in the health care system, technology such as social alarms and sensors has been implemented in people’s homes with the goal of increasing independent living for elderly and multimorbid health care recipients. When implementing technology, someone needs to monitor and answer the alarms and calls, which is often coined ‘telecare’. …”
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