Neoadjuvant pembrolizumab-carboplatin-paclitaxel in locally advanced squamous cell carcinoma of the oral cavity: A case report and literature review by Abdulrahman Hesham, Fawaz AlOtaibi, D. David Kim, Yousef Alshamrani, Joao Hyppolito, Katie Jubala

“…Head and neck cancers are being diagnosed more frequently in elderly patients and at advanced stages. In these cases, standard treatment methods are often not feasible due to patient frailty and malnutrition. …”
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Characterization of Ischemic Cerebrovascular Disease in Diabetic Patients at the General Calixto García Clinical Surgical University Hospital by Yunier Angarica Aguilar, Jorge Félix Salazar Rodríguez, Damaris Herrera Arrebato, Emelina Despaigne Carrión, María de los Ángeles Hechevarría Heredia, César Emilio Reina Rodríguez

“…<strong><br />Conclusions:</strong> cerebrovascular disease was more frequent in males, white skin color and elderly patients. Arterial hypertension, overweight, hyperglycemia as well as high cholesterol and triglyceride values predominated in the sample and were related to the greater severity of the ischemic cerebrovascular event.…”
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A comprehensive analysis of trends in the burden of gout in China and globally from 1990 to 2021 by Shiwei Xie, Heng Xiao, Lei Xu, Gengwu Li, Fan Zhang, Mingwei Luo

“…Our analysis indicated that middle-aged and elderly populations, particularly males, are at higher risk for gout. …”
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Usefulness of body composition assessment by bioelectrical impedance vector analysis in subacute post-stroke patients in rehabilitation by Alessandro Guerrini, Mariacristina Siotto, Carola Cocco, Marco Germanotta, Valeria Cipollini, Laura Cortellini, Arianna Pavan, Stefania Lattanzi, Sabina Insalaco, Yeganeh Manon Khazrai, Irene Giovanna Aprile

“…BIVA revealed that both adult patients (< 65 years, n = 29) and elderly patients (≥ 65 years, n = 58) exhibited high body fluid overload and low muscle mass. …”
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A systematic review of the clinical use of a single-layer bovine collagen-elastin acellular dermal matrix by David M. Hill

“…Cases varied considerably and included: burns, acute traumatic injuries, chronic wounds, and soft tissue reconstruction in patients ranging from pediatric to the elderly. A single-stage procedure (CEM placement and covered with an autograft in the same procedure) was the most reported technique, but autograft application in a later procedure was also reported. …”
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Bioinformatics approach reveals the critical role of inflammation-related genes in age-related hearing loss by Xi Gu, Chenyu Chen, Yuqing Chen, Chaojun Zeng, Yanchun Lin, Ruosi Guo, Shujin Xu, Chang Lin

“…Abstract Age-related hearing loss (ARHL) is the most prevalent sensory impairment in the elderly. However, the pathogenesis of ARHL remains unclear. …”
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A prediction study on the occurrence risk of heart disease in older hypertensive patients based on machine learning by Fei Si, Qian Liu, Jing Yu

“…Abstract Objective Constructing a predictive model for the occurrence of heart disease in elderly hypertensive individuals, aiming to provide early risk identification. …”
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The Silent Threat of Human Metapneumovirus: Clinical Challenges and Diagnostic Insights from a Severe Pneumonia Case by Rubens Carmo Costa-Filho, Felipe Saddy, João Luiz Ferreira Costa, Leandro Reis Tavares, Hugo Caire Castro Faria Neto

“…While severe disease manifestations are traditionally associated with pediatric, elderly, or immunocompromised patients, hMPV-related pneumonia in immunocompetent adults remains underexplored. …”
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Clostridium Difficile and COVID-19: Novel Risk Factors for Acute Portal Vein Thrombosis by Venkata Ram Pradeep Rokkam, Gurusaravanan Kutti Sridharan, Rathnamitreyee Vegunta, Radhakrishna Vegunta, Umesha Boregowda, Babu P. Mohan

“…We report a case of an elderly female with a recent diagnosis of COVID-19 and no prior history of cirrhosis or malignancy who presented with diarrhea due to clostridium difficile infection. …”
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Investigation of customized total knee implant with articular cartilage under loading conditions using finite element analysis. by Shady A Alshewaier, Mohamed Yacin Sikkandar, Ali Ahmed Ali Almakrami, S Sabarunisha Begum, Ahmad Alassaf, Ibrahim AlMohimeed, S Meenatchi Sundaram, Dheeraj Poojary, Natteri M Sudharsan, Eddie Y K Ng

“…Knee osteoarthritis (KOA) is a degenerative joint disease predominantly affecting the elderly and is often managed through knee replacement surgeries. …”
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Prevalence of Hypertension and Associated Factors among Residents Aged ≥18 Years in Ganzhou, China: A Cross-Sectional Study by Junwang Gu, Qi Wang, Wei Qiu, Fen Lin, Chunmei Wu, Ming Hao, Ping Wu

“…Univariate logistic regression analysis revealed that multiple variables have a statistically significant effect on the prevalence of hypertension. The elderly (odds ratio [95% CI]: 2.791 [2.594–3.004]), men (1.805 [1.583–2.058]), lower educated (0.848 [0.805–0.893]), a family history of hypertension (4.575 [3.900–5.368]), higher body mass index (1.344 [1.215–1.488]), central obesity (1.532 [1.304–1.799]), and less vegetable intake (1.150 [1.023–1.294]) were the major risk factors for hypertension. …”
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Cost-Effectiveness and Budget Impact of Emerging Minimally Invasive Surgical Treatments for Benign Prostatic Hyperplasia by Bilal Chughtai, Sirikan Rojanasarot, Kurt Neeser, Dmitry Gultyaev, Stacey L. Amorosi, Neal D. Shore

“…**Background:** Benign prostatic hyperplasia (BPH) is one of the most prevalent and costly chronic conditions among middle-aged and elderly men. Prostatic urethral lift (PUL) and convective water vapor thermal therapy (WVTT) are emerging minimally invasive surgical treatments as an alternative to traditional treatment options for men with moderate-to-severe BPH. …”
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Integrated care for older people based on information and communication technology: a scoping review protocol by Yan Zhang, Shanshan Wang, Yutong Tian, Qingyun Cheng, Lixue Meng

“…Introduction Integrated care is an effective means of coping with the increasingly complex healthcare needs of elderly and alleviating pressure on national pension services. …”
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Review of Postgraduate Dissertations on Alzheimer's Patients in Nursing Care by Fadime Toru

“…Increasingly, health problems have started to occur in the increasing elderly population. The physical and psychological problems that occur with aging have brought the search for new care and treatment methods to the agenda, and with the increase in life expectancy, there has been an increase in the diseases that may occur in individuals. …”
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Prognostic Factors and Nomogram for Malignant Brainstem Ependymoma: A Population‐Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis by Xiaoyu Ji, Siyuan Yang, Dejing Cheng, Wenbo Zhao, Xuebo Sun, Fang Su

“…Different treatment methods have no significant difference in the overall survival probability of the elderly group. Conclusions Individuals who are Black and anaplastic ependymomas were negative risk factors for brainstem ependymoma associated with an increased risk of mortality. …”
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Factors Influencing Postoperative Inpatient Rehabilitation Requirement After Surgical Intervention for Isolated Hip Fracture: A Multicenter Study by Daniel J. Lynch, Andrew Romero, James P. McFadden, Peter Zeblisky, Huazhi Liu, Darwin Ang

“…ABSTRACT Purpose Hip fractures in the elderly, especially those discharged to a rehab facility, have historically been associated with poor outcomes. …”
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Preoperative management in octogenarian patients with rectal cancer by Arthur M. Damasceno, Rubens Kesley, Marcus Valadão, Fabrício Braga, Cristiane A. D'Almeida, Marcos B. Pitombo

“…Rectal tumors often occur in elderly patients. Methods: Between January and August 2024, 6 experts in colorectal cancer met to develop an algorithm to organize the interdisciplinary and multimodal preoperative approaches in the octogenarian population with rectal cancer. …”
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A Case of Diffuse Leptomeningeal Glioneuronal Tumor Misdiagnosed as Chronic Tuberculous Meningitis without Brain Biopsy by Jung-goo Lee, Hak-cheol Ko, Jin-gyu Choi, Youn Soo Lee, Byung-chul Son

“…His delayed diagnosis of DLGNT might be due to prevalence of tuberculosis in our country, similarity in MRI finding of prominent leptomeningeal enhancement in the basal cisterns, and extreme rarity of DLGNT in the elderly. DLGLT should be considered in differential diagnosis of medical conditions presenting as communicating hydrocephalus with prominent leptomeningeal enhancement. …”
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Optimal exercise modalities and doses for therapeutic management of osteoarthritis of the knee by Max Whitfield, Owen W. Tomlinson

“…Benefits to KOA management was observed in everyone, including the elderly, obese, and those with severe KOA. Although, in those with severe KOA, walking was observed to only prevent further deterioration, rather than induce any symptomatic improvement. …”
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Development and validation of a nomogram to predict the probability of death after surgical evacuation for traumatic intracranial hemorrhage by Yan-Chao Zheng, Jun-Wei Qian, An-Ni Li, Yi-Nuo Yuan, Sen-Lin Ma, Mingquan Chen

“…In this study, we found that the tICH-related mortality rate was 11.42% (28/245). In the elderly cohort aged ≥ 65 years, the mortality rate increased to 28.13%(18/64). …”
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