Basis for the Age-related Decline in Intestinal Mucosal Immunity by Douglas L. Schmucker, Robert L. Owen, Robert Outenreath, Karine Thoreux

“…The elderly are characterized by mucosal immunosenescence and high rates of morbidity and mortality associated with infectious diseases of the intestinal tract. …”
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A scoping review on bio-aerosols in healthcare and the dental environment. by Charifa Zemouri, Hans de Soet, Wim Crielaard, Alexa Laheij

“…Legionella species were found to be a bio-aerosol dependent hazard to elderly and patients with respiratory complaints. …”
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Sex-specific associations of prenatal Chinese famine exposure with cataract risk at age sixty: a cross-sectional study by Yuanyou Xia, Xiaoyang Xu, Siyao Wang

“…Abstract Background Age-related cataract (ARC) is among the most common blinding eye disorders among the elderly. Prenatal nutrition may cause irreversible damage to the development of the ocular crystalline lens. …”
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Interaction between dipeptidyl-peptidase-4 inhibitors and drugs acting on renin angiotensin aldosterone system for the risk of angioedema: a pharmacovigilance assessment using disp... by Kannan Sridharan, Gowri Sivaramakrishnan

“…Angioedema occurred predominantly in elderly patients (> 65 years) and females. Sixteen case reports corroborated the findings from the database assessment. …”
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Rising Incidence and Comorbidities of Endogenous Hypothyroidism in Republic of Korea from 2004 to 2018: A Nationwide Population Study by Chae Won Chung, Hwa Young Ahn, Sun Wook Cho, Ka Hee Yi

“…The incidence of endogenous hypothyroidism is increasing more rapidly in men than in women, especially in the elderly. Patients with endogenous hypothyroidism seem to have a heightened risk for cerebrovascular disease and mood disorders.…”
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The prevalence and outcomes of pre‐admission vitamin D levels in the management of proximal femur fractures by Aysha Rajeev, Connor Hunter, Saurav Krishnan, Atta Ullah, George Koshy, Gateshead Health Foundation NHS Trust

“…The aim of this study was to examine the prevalence of vitamin D deficiency in elderly patients with fragility fractures of the hip by estimating 25‐hydroxyvitamin D levels and to assess whether low vitamin D levels at the time of admission affect functional outcomes at 3 months and mortality at 28 days and 1 year. …”
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Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study by Junqing Wang, Huanfen Zhou, Limin Qin, Chunxia Peng, Jie Zhao, Da Teng, Dahe Lin, Nanping Ai, Quangang Xu, Shihui Wei

“…At last follow-up, 14.5% were diagnosed with neuromyelitis optica spectrum disorder (NMOSD), 1.3% were diagnosed with multiple sclerosis (MS), 5.2% with chronic relapsing inflammatory optic neuropathy, 1.3% with infectious ON, and 19.7% with autoimmune ON. None of the elderly group (≥65 years) developed NMOSD or MS. Conclusion. …”
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Elevated Salivary Inflammatory Biomarkers are Associated with SARS-CoV-2 Infection Severity by Hanadi Abdullah Alwafi, Soad Shaker Ali, Sunil Babu Kotha, Layla Waleed Abuljadayel, Maha Ibrahim, Ibrahim Rashad Noor Elahi, Hebah Abdullah Alwafi, Mohammed S. Almuhayawi, Matthew D. Finkelman, Nagla A. El-Shitany

“…Among patients with SARS-CoV-2 infection, men showed significantly higher CRP and CXCL-10 levels than females (p<0.01 and 0.05, respectively). In addition, elderly patients (40–80 years) had significantly higher IL-6, CRP, and CXCL-10 (p<0.001). …”
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The challenges of using Escherichia coli as a host in recombinant insulin production by Muhammad Taher

“…In Malaysia, the prevalence of diabetes mellitus (DM), depends on factors such as gender, age, and ethnicity, with women, the elderly, and the Indian community having the highest prevalence of DM. …”
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GENDER AND AGE SPECIFIED PREVALENCE OF OSTEOPOROSIS ANDOSTEOPENIA IN AN APPARENTLY HEALTHY PAKISTANI POPULATION by Zuneera Akram, Fatima Zahra, Rehana Perveen, Muzammil Hussain, Aisha Noreen, Maryam Inayat, Sobia Akhter, Usman Ghani Farooqi

“…Body mass index, and lifestyle including (smoking, physical activity, and diet) were correlated with BMD. In elderly patients’ osteoporosis and osteopenia are common conditions that can seriously affect their quality of life. …”
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An Unsuspected Finding of t(9;22): A Rare Case of Philadelphia Chromosome-Positive B-Lymphoblastic Lymphoma by Prajwal Boddu, C. Cameron Yin, Rashmi Kanagal-Shamanna, Guillin Tang, Beenu Thakral, Tapan Kadia, Marina Konopleva, Elias Jabbour, Nitin Jain

“…In this report, we illustrate the case of an elderly gentleman who presented with isolated testicular and vertebral LBL involvement but had no morphologic bone marrow involvement. …”
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Depression among Tibetan residents in the Southeastern region of Qinghai-Tibet plateau: a cross-sectional study by Yuji Chen, Ga Long, Qing Huang, Ping Zhang, Nie Xu

“…Logistic regression analysis showed that middle-aged (OR 2.86, 95% CI 1.69–4.82, P < 0.01) and elderly people (OR 2.27, 95% CI 1.30–3.98, P < 0.01), living in ultra-high altitude areas (OR 3.48, 95% CI 1.35–2.91, P < 0.01) and low BMI (OR   4.31, 95% CI 1.33–13.93) are high-risk factors for depression. …”
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Thyrotropin reference interval in older adults by Xiaodan Zhai, Yongze Li, Xiaochun Teng, Weiping Teng, Xiaoguang Shi, Zhongyan Shan

“…Therefore, a higher thyrotropin threshold for diagnosing and treating subclinical hypothyroidism in the elderly seems reasonable.…”
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Efficient Feature Selection and Hyperparameter Tuning for Improved Speech Signal-Based Parkinson’s Disease Diagnosis via Machine Learning Techniques by Deepak Painuli, Suyash Bhardwaj, Utku Kose

“… Parkinson’s disease (PD) is a neurodegenerative disorder that progressively worsens with age, particularly affecting the elderly. Symptoms of PD include visual hallucinations, depression, autonomic dysfunction, and motor difficulties. …”
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The process and logical mechanism of agricultural production space contraction in mountainous areas based on actor-network theory：A case study of Lishi Village in Longde County, Ni... by CHEN Kunqiu, CHEN Yunya, LIANG Yajia, ZHENG Yuhan

“…[Conclusion] To address the contraction of agricultural production space contraction in mountainous areas, it is necessary to innovate the mode of agricultural production and management, rationally balance the relationship between environmental carrying capacity and agricultural development, innovate the policies of ecological compensation and agricultural benefit, and accelerate the cultivation of new types of business entities such as elderly-friendly agriculture and professional farmers.…”
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Analyzing the cancer mortality-to-incidence ratios and health expenditures in the aging population: a 20-year comparative study across high-income countries by Majed Ramadan, Shadell AlGhamdi, Rawiah Alsiary

“…The implications are profound, suggesting an impending strain on healthcare systems, particularly in nations with a high proportion of elderly and low health expenditures.…”
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Global, regional and national burden of tracheal, bronchus, and lung cancer attributable to ambient particulate matter pollution from 1990 to 2021: an analysis of the global burden... by Jianguo Lu, Xiangmei Zhao, Shaoyin Gan

“…Results The ASDR per 100,000 population of TBL cancer attributable to ambient particulate matter pollution increased by 0.2%[95% UI 0.1 to 0.3] to 79.6[95% UI 49.0 to 111.2] from 1990 to 2021 Globally. Middle-aged and elderly individuals accounted for the majority of the disease burden, with the highest value at the 65–69 years. …”
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Older generation in region’s labor market: the analysis of demographic and economic components by N. V. Borovskikh, E. A. Kipervar

“…The importance of the older generation in the social development of the region is noted and the role of participation of this group in labor activity is determined, which necessitates the creation of favorable conditions for the realization of its resource potential, which should involve the development and implementation of appropriate health-saving programs, as well as a change in the socio-cultural paradigm of «old age» that creates representation of the elderly as an unproductive part of society…”
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Microbiota from young mice counteracts susceptibility to age-related gout through modulating butyric acid levels in aged mice by Ning Song, Hang Gao, Jianhao Li, Yi Liu, Mingze Wang, Zhiming Ma, Naisheng Zhang, Wenlong Zhang

“…Gout is a prevalent form of inflammatory arthritis that occurs due to high levels of uric acid in the blood leading to the formation of urate crystals in and around the joints, particularly affecting the elderly. Recent research has provided evidence of distinct differences in the gut microbiota of patients with gout and hyperuricemia compared to healthy individuals. …”
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Evaluation of machine learning-based regression techniques for prediction of diabetes levels fluctuations by Badriah Alkalifah, Muhammad Tariq Shaheen, Johrah Alotibi, Tahani Alsubait, Hosam Alhakami

“…Middle-Aged and Elderly people today face a variety of health problems as a result of their modern lifestyle, which includes increased work stress, less physical activity, and altered food habits. …”
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