The comparative studies of Borneo plant extracts to increases vaccine efficacy in tilapia, Oreochromis niloticus by Esti Handayani Hardi, Komsanah Sukarti, Maulina Agriandini, Irawan Wijaya Kusuma, Rudi Agung Nugroho

“…ABSTRACT   This study was investigated the adjuvant effect of Boesenbergia pandurata (BP), Zingiber zerumbet (ZZ), Solanum ferox (SF) on protection of tilapia with injection Pseudomonas sp. …”
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An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept studyResearch in context by Marirena Bafaloukou, Ann-Kathrin Schalkamp, Nan Fletcher-Lloyd, Alex Capstick, Chloe Walsh, Cynthia Sandor, Samaneh Kouchaki, Ramin Nilforooshan, Payam Barnaghi

“…Current interventions for agitation are primarily medication-based, which may lead to severe side effects and lack personalisation. Understanding how real-world factors interact with agitation within home settings offers a promising avenue towards identifying potential personalised non-pharmacological interventions. …”
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COVID-19 – if the cure is worse than the disease. The Italian chaos by Giuseppe FERRARI

“…Moreover, it has not been accurately considered the real feasibility to enforce an efficient social distancing model and the effects of a prolonged lockdown on the Italian economy. …”

Unveiling neurogenic biomarkers for the differentiation between sepsis patients with or without encephalopathy: an updated meta-analysis by Jiyun Hu, Wenchao Li, Shucai Xie, Ya Liao, Tao Chen, Xinrun Wang, Weiping Xia, Fang Huang, Zhaoxin Qian, Lina Zhang

“…Heterogeneity among the included studies was examined using the I 2 statistic and random-effects model was applied owing to large heterogeneity. …”
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BRAF inhibitor monotherapy in BRAFV600E-mutated pediatric low-grade glioma: a single center’s experience by S. S. McThenia, S. S. McThenia, S. S. McThenia, K. M. Reddy, K. M. Reddy, E. Damaraju, E. Castellino, Z. He, R. Beer, F. Chien, F. Chien, F. Chien, R. C. Castellino, R. C. Castellino, R. C. Castellino, A. E. Goldman-Yassen, A. E. Goldman-Yassen, J. R. Fangusaro, J. R. Fangusaro, J. R. Fangusaro, T. MacDonald, T. MacDonald, T. MacDonald

“…Two of 15 patients (13%) discontinued therapy due to toxicities, and 2 other patients switched within drug class from vemurafenib to dabrafenib due to toxicities.DiscussionIn this small cohort of incompletely resected BRAFV600E mutated pLGGs, BRAFi monotherapy was effective and well tolerated with an ORR comparable to published prospective outcomes of dual MEK/BRAF inhibitor therapy. …”
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Comparative evaluation of multimarker algorithms for early-stage HCC detection in multicenter prospective studies by Jinlin Hou, Thomas Berg, Arndt Vogel, Teerha Piratvisuth, Jörg Trojan, Enrico N. De Toni, Masatoshi Kudo, Katarina Malinowsky, Peter Findeisen, Johannes Kolja Hegel, Wenzel Schöning, Kairat Madin, Konstantin Kroeniger, Henry Lik-Yuen Chan, Ashish Sharma

“…Our study provides supporting evidence that in participants with CLD undergoing guideline-directed HCC surveillance, the GAAD (Cobas) algorithm may be used as an effective method for the detection of HCC, potentially resulting in improved patient outcomes.…”
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Biogas quality and nutrient remediation in palm oil mill effluent through Chlorella vulgaris cultivation using a photobioreactor by T. Handayani, I.N. Djarot, N. Widyastuti, F.D. Arianti, A. Rifai, A.I. Sitomurni, M.M.A. Nur, R.N. Dewi, N. Nuha, J. Haryanti, D. Pinardi, Y. Suryana, A. Aziz, E. Syamsudin, T. Rochmadi, P.A. Lomak, A. Hadi, M.D. Pertiwi, E. Yuniastuti, N.A. Putri

“…Furthermore, Chlorella vulgaris showcased its ability to effectively eliminate nutrient nitrogen, reaching a removal rate of 90 percent at an optical density of 0.2. …”
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LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype by Nadia Cobo‐Vuilleumier, Silvia Rodríguez‐Fernandez, Livia López‐Noriega, Petra I. Lorenzo, Jaime M. Franco, Christian C. Lachaud, Eugenia Martin Vazquez, Raquel Araujo Legido, Akaitz Dorronsoro, Raul López‐Férnandez‐Sobrino, Beatriz Fernández‐Santos, Carmen Espejo Serrano, Daniel Salas‐Lloret, Nila vanOverbeek, Mireia Ramos‐Rodriguez, Carmen Mateo‐Rodríguez, Lucia Hidalgo, Sandra Marin‐Canas, Rita Nano, Ana I. Arroba, Antonio Campos Caro, Alfred CO Vertegaal, Alejandro Martín‐Montalvo, Franz Martín, Manuel Aguilar‐Diosdado, Lorenzo Piemonti, Lorenzo Pasquali, Roman González Prieto, Maria Isabel García Sánchez, Decio L. Eizirik, Maria Asuncion Martínez‐Brocca, Marta Vives‐Pi, Benoit R. Gauthier

“…Abstract Background The complex aetiology of type 1 diabetes (T1D), characterised by a detrimental cross‐talk between the immune system and insulin‐producing beta cells, has hindered the development of effective disease‐modifying therapies. The discovery that the pharmacological activation of LRH‐1/NR5A2 can reverse hyperglycaemia in mouse models of T1D by attenuating the autoimmune attack coupled to beta cell survival/regeneration prompted us to investigate whether immune tolerisation could be translated to individuals with T1D by LRH‐1/NR5A2 activation and improve islet survival. …”
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Trifluridine-tipiracil in previously treated patients with oestrogen receptor-positive, HER2-negative metastatic breast cancer (BOOG 2019-01 TIBET trial): a single-arm, multicentre... by Niels A.D. Guchelaar, Ron H.J. Mathijssen, Maaike de Boer, Marlies L. van Bekkum, Joan B. Heijns, Birgit E.P.J. Vriens, Mandy M. van Rosmalen, Lonneke W. Kessels, Lisanne Hamming, Karin J. Beelen, Peter Nieboer, Susan M. van den Berg, Esther Oomen-de Hoop, Rhodé M. Bijlsma, Monique E.M.M. Bos

“…Summary: Background: Effective later-line chemotherapy treatment options are scarce for patients with metastatic breast cancer (MBC). …”
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Dynamic Challenges of Active Tuberculosis: Prevalence and Risk Factors of Co-Infection in Clinical and Microbiological Characteristics at King Abdulaziz University Hospital, Jeddah... by Mokhtar JA, Attallah DM, Jiman-Fatani AA, Al-Rabia MW, Alqarni MA, Saleh BH, Amboon MM, Altorki TA, Alkuwaity KK, Abujamel T, Kaki R, Albarakati TN, Daghistani H, Ismail MA, Alharbi O, Abu ITM, Alfadil A, Ibrahem K, Mufrrih M, Sait AM

“…Patients undergoing hemodialysis, and those with respiratory comorbidities, cancer, diabetes, and smoking were found to have a higher mortality hazard, indicating these as significant risk factors for TB.Conclusion: This study highlights TB’s prevalence and drug resistance at KAUH, emphasizing high-risk groups, including males and young adults. Effective strategies, targeted interventions, and future research are vital for reducing mortality.This study examines the stability of tuberculosis (TB) disease presentation using dynamic models among patients treated at King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia.Key findings include:This is the first study to analyze TB disease stability across different demographic groups.Males, elderly individuals, cancer patients, and those with pulmonary disease or other comorbidities were found to have a higher risk of death from TB.The results emphasize the need for healthcare practices to adopt the “equilibrium state” method for hazard assessment. …”
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La chirurgie cardiaque mini-invasive vidéo-assistée : une étude comparative à la voie conventionnelle [Less-invasive video-assisted cardiac surgery : a comparative study with the c... by Sami Bouchenafa, Ahmed Zaki Boukli-Hacene, Boukri Hamouda, Mohamed Atbi

“…Conclusion - The minimally invasive video-assisted is a simpler, safer and more effective procedure with excellent results and low morbidity. …”
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The concerted actions of microRNA-29a and interferon-β modulate complete Freund's adjuvant-induced inflammatory pain by regulating the expression of type 1 interferon receptor, int... by Chien-Cheng Liu, Kuo-Chuan Hung, Yu-Yu Li, Eagle Yi-Kung Huang, Chin-Chen Chu, Lok-Hi Chow, Ping-Heng Tan

“…Background: Previous research has shown that type 1 interferons (IFN), such as IFN-α and IFN-ß, possess antiviral and antinociception effects. Elevated levels of microRNA-29a (miR-29a) have been observed during inflammatory pain, and as miR-29a targets the type 1 IFN receptor (IFNR1), our study aimed to investigate the involvement of miR-29a, type 1 IFN, and IFNR1 in inflammatory pain. …”
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La chirurgie cardiaque mini-invasive vidéo-assistée : une étude comparative à la voie conventionnelle [Less-invasive video-assisted cardiac surgery : a comparative study with the c... by Sami Bouchenafa, Ahmed Zaki Boukli-Hacene, Boukri Hamouda, Mohamed Atbi

“…Conclusion - The minimally invasive video-assisted is a simpler, safer and more effective procedure with excellent results and low morbidity. …”
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Investigating the hatchability and nauplii biometry of Artemia franciscana in unconventional waters of Sistan region, Southeast Iran by Hashem Khandan Barani, Abdolali Rahdari, Narjes Sanchooli, Ali Khosravanizadeh

“…Using these water sources for aquaculture is suggested for optimal utilization and reduction of their adverse effects on the environment. Artemia is an aquatic crustacean that is distributed all over the world. …”
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New Insights into Duckweed as an Alternative Source of Food and Feed: Key Components and Potential Technological Solutions to Increase Their Digestibility and Bioaccessibility by Krisztina Takács, Rita Végh, Zsuzsanna Mednyánszky, Joseph Haddad, Karim Allaf, Muying Du, Kewei Chen, Jianquan Kan, Tian Cai, Péter Molnár, Péter Bársony, Anita Maczó, Zsolt Zalán, István Dalmadi

“…More research is needed on how to effectively incorporate duckweed into diverse cuisines and dietary patterns. …”
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An alternative to the straddle-arm technique for a conscious infant who is choking: Towards a more universal skill by Ada Chan, Adam Gesicki

“…We aimed to identify a more effective set of practices for holding an infant during the delivery of back blows and chest thrusts. …”
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Jinbei oral liquid for idiopathic pulmonary fibrosis: a randomized placebo-controlled trial by Aijun Zhang, Kangkang Han, Fangfang Chen, Xiao Chen, Jun Wang, Yikai Niu, Zhaoqiu Hu, Chunyan Zheng, Liping Han, Zhaoqing Meng, Liangzong Zhang, Qingcui Xu, Cuixiang Yu, Wei Zhang, Quanguo Li, Ningning Tao, Weixiang Kong, Fei Liu, Min Wang, Juanjuan Jiang, Honglin Li, LongBin Pang, Huaichen Li

“…Having been used for over 30 years in the treatment of pulmonary diseases, JBOL was evaluated in this study in order to assess its effect on idiopathic pulmonary fibrosis as well as its safety (ChiCTR2000035351, Chictr.org.cn.09/08/2020). …”
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miR-317 regulates the proliferation and apoptosis of duck follicle granulosa cells by targeting VIPR1 by Li Li, Qingwu Xin, Linli Zhang, Zhongwei Miao, Zhiming Zhu, Xiaopan Liu, Qiannan Cai, Wenli Shi, Bangzhe Zhao, Changtao Liu, Zhengkui Zhou, Azheng Liang, Qinlou Huang, Nenzhu Zheng

“…The purpose of this study was to investigate the effects of miR-317 overexpression or silencing on VIPR1 gene and protein expression in duck follicle granulosa cells. …”
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Long-Term Evaluation of GCOM-C/SGLI Reflectance and Water Quality Products: Variability Among JAXA G-Portal and JASMES by Salem Ibrahim Salem, Mitsuhiro Toratani, Hiroto Higa, SeungHyun Son, Eko Siswanto, Joji Ishizaka

“…The assessment of temporal consistency and seasonal variations in <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mrow><mi>R</mi></mrow><mrow><mi>r</mi><mi>s</mi></mrow></msub></mrow></semantics></math></inline-formula> data shows that both platforms effectively capture interannual trends and maintain temporal stability, particularly from the 490 nm band onward, underscoring the potential of SGLI data for long-term monitoring of coastal and oceanic environments.…”
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Application of Concentration-Area fractal modeling and artificial neural network to identify Cu, Zn±Pb geochemical anomalies in Hashtjin area, NW of Iran by Ali Imamalipour, Hamed Ebrahimi, Amir reza Abdollahpur

“…ML-based approaches to mineral prospectivity mapping using geochemical data can more effectively identify statistical correlations between geochemical patterns than other non-ML methods. …”
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