3-methyl-4-nitrophenol disturbs the maternal-to-zygotic transition of early embryos by damaging mitochondrial function and histone modification by Fan Chen, An-Feng Luo, Kai-Xin Pan, Hao Gu, Chang-Fan Zhou, Wei Zeng, Song Liu, Adrian Molenaar, Hong-Yan Ren, Li-Jun Huo, Yan-Zhen Bi

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Quality evaluation and influencing factors analysis of 6-minute walking test in coronary heart disease patients (冠心病患者6分钟步行试验质量评价与原因分析) by WANG Shanshan (王珊珊)

“…It is suggested that quality of 6MWT should be strengthened from following aspects: patient health education, kinesiophobia, financial burden, time of conducting 6MWT after PCI and role of cardiac rehabilitation specialist nurses. …”
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Positron emission tomography for phenotyping inflammation of cardiovascular diseases by Xiaoyun Luo, Chentao Jin, Hetian Chen, Xiaohui Zhang, Yan Zhong, Peili Cen, Hong Zhang, Mei Tian

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Hubungan Status Gizi dengan Status Sosial Ekonomi Keluarga Murid Sekolah Dasar di Daerah Pusat dan Pinggiran Kota Padang Lisbet Rimelfhi Sebataraja, by Lisbet Rimelfhi Sebataraja, Fadil Oenzil, Asterina .

“…Nutritional status associated with Economic level of families, father and mother's education level and number of children in families.…”
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Enhancement of Executive Functions but Not Memory by Multidomain Group Cognitive Training in Patients with Parkinson’s Disease and Mild Cognitive Impairment: A Multicenter Randomiz... by Elke Kalbe, Ann-Kristin Folkerts, Anja Ophey, Carsten Eggers, Saskia Elben, Karina Dimenshteyn, Patricia Sulzer, Claudia Schulte, Nele Schmidt, Christian Schlenstedt, Daniela Berg, Karsten Witt, Lars Wojtecki, Inga Liepelt-Scarfone

“…Regression analyses revealed cognitive baseline levels, education, levodopa equivalent daily dose, motor scores, and ApoE status as significant predictors for CT success. …”
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Sequence of episodic memory-related behavioral and brain-imaging abnormalities in type 2 diabetes by Bo Hu, Ying Yu, Xin-Wen Yu, Min-Hua Ni, Yan-Yan Cui, Xin-Yu Cao, Ai-Li Yang, Yu-Xin Jin, Sheng-Ru Liang, Si-Ning Li, Pan Dai, Ke Wu, Lin-Feng Yan, Bin Gao, Guang-Bin Cui

“…Results T2D patients exhibited poorer memory, general cognitive function, and executive function compared to healthy controls after controlling age, sex, and education level. In the progression of T2D, functional interaction between brain regions showed abnormalities first, followed by memory tests, the cerebral spontaneous neural activity, and finally the gray matter volume. …”
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Improving the provision of clinical pharmacy services in low- and middle-income countries: a qualitative study in tertiary health facilities in Tanzania by Fredrick Kalokola, Dorkasi L Mwakawanga, Ritah F Mutagonda, Hamu J Mlyuka, Wigilya P Mikomangwa, Manase Kilonzi, Wema A Kibanga, Alphonce Ignace Marealle, Bertha Mallya, Deogratias Katabalo, Sofia Sanga, John Rwegasha, Rose Magambo, John Mmassy, Sungwa Kabissi, Josephine A Balati, Peter Maduki, Omary Mashiku Minzi, Appolinary A R Kamuhabwa

“…The reported challenges in providing CPS include healthcare structures, public policies, resources, workforce, culture and education inequalities. This study aimed to explore the strategies to improve the provision of CPS in tertiary health facilities in Tanzania.Methods This study was conducted between August and September 2021. …”
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Prevalence of dyslipidemia and its influencing factors among adult residents in Hebei province: a cross-sectional survey by Qianyu LI, Yajing CAO, Lijuan TANG, Yuhuan LIU, Xiaoying LU, Qi QI, Shifan WANG, Xiaoli LIU, Ze CUI

“…Unconditional multivariate logistic regression analysis showed that among adult residents, age ≥ 25 years, current smoking, overweight, obesity, central obesity, body fat percentage ≥ 27.2%, and basal metabolic rate ≥ 1 504 kcal were risk factors for dyslipidemia, whereas female gender, rural residence, and sedentary time of 2 – 4 hours per day were protective factors against dyslipidemia; age ≥ 25 years, college education or higher, current smoking, central obesity, and body fat percentage ≥ 37.9% were risk factors for hypercholesterolemia, whereas a basal metabolic rate of 1 199 – 1 503 kcal was a protective factor; age 25 – 64 years, current smoking, consumption of animal and poultry meat 300 – 500 g per week, overweight, obesity, central obesity, and body fat percentage ≥ 27.2% were risk factors, whereas female gender was a protective factor for hypertriglyceridemia; age ≥ 25 years, central obesity, sedentary time ≥ 2 hours per day, and body fat percentage ≥ 37.9% were risk factors, whereas basal metabolic rate 1 199 – 1 503 kcal was a protective factor for hyper-LDL-C; ethnic minority, current smoking, overweight, obesity, central obesity, physical inactivity, body fat percentage 33.0% – 37.8%, and basal metabolic rate ≥ 1 327 kcal were risk factors, whereas being female, aged 45 – 54 years, living in rural areas, drinking alcohol, consuming livestock and poultry meat > 500 g per week, and being sedentary for ≥ 2 hours per day were protective factors for hypo-HDL-C. …”
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Perspectives and Practices of Healthcare Leaders in Supporting Healthcare Worker Well-Being: A Reality Check by Reijmerink IM, van der Laan MJ, Scheele F, Wietasch JKG

“…Iris M Reijmerink,1 Maarten J van der Laan,1 Fedde Scheele,2,3 J K Götz Wietasch4 1Department of Surgery, University Medical Centre Groningen, Groningen, the Netherlands; 2Amsterdam Academic Medical Center, Research in Education, Amsterdam, the Netherlands; 3Athena Institute for Trans-Disciplinary Research, the Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; 4Department of Anaesthesiology, University Medical Centre Groningen, Groningen, the NetherlandsCorrespondence: Iris M Reijmerink, UMCG, Hanzeplein 1, Groningen, 9713GZ, The Netherlands, Tel +316 38 15 85 58, Email i.m.reijmerink@umcg.nlIntroduction: The well-being of healthcare workers (HCWs) is a critical concern. …”
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A prospective multi-site study to evaluate the performance and usability of an oral fluid-based HIV self-test in Canada by Richard A. Galli, Darshanand Maraj, Kristin McBain, Jason M. Lo Hog Tian, Abbey McFarland, Wangari Tharao, Nontobeko P. Nkala, Arlene Chan, Mark da Silva, Rejean Thomas, Anne-Fanny Vassal, Martin Lepage, Laurie Ireland, Mike Payne, Jared Starr, Chris Fraser, Marion Selfridge, Mona Loutfy, Roberta Halpenny, Nirubini Jeyarajah, Vanessa Tran, Tony Mazzulli, Sean B. Rourke

“…With respect to sociodemographics: 84% of participants were between 18–45 years of age, 73% had at least a college education, 48% were Cis-male, 45% were employed; and 26% identified as White, 23% as African, Caribbean or Black, 5% as Indigenous [First Nations, Métis or Inuit], 33% as Asian, and 6% as LatinX. …”
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RADAR-AD: assessment of multiple remote monitoring technologies for early detection of Alzheimer’s disease by Manuel Lentzen, Srinivasan Vairavan, Marijn Muurling, Vasilis Alepopoulos, Alankar Atreya, Merce Boada, Casper de Boer, Pauline Conde, Jelena Curcic, Giovanni Frisoni, Samantha Galluzzi, Martha Therese Gjestsen, Mara Gkioka, Margarita Grammatikopoulou, Lucrezia Hausner, Chris Hinds, Ioulietta Lazarou, Alexandre de Mendonça, Spiros Nikolopoulos, Dorota Religa, Gaetano Scebba, Pieter Jelle Visser, Gayle Wittenberg, Vaibhav A. Narayan, Neva Coello, Anna-Katharine Brem, Dag Aarsland, Holger Fröhlich, on behalf of RADAR-AD

“…Our approach involved a univariate analysis using Analysis of Covariance (ANCOVA) to analyze individual features of six RMTs while adjusting for variables such as age, sex, years of education, clinical site, BMI and season. Additionally, we employed four machine learning classifiers – Logistic Regression, Decision Tree, Random Forest, and XGBoost – using a nested cross-validation approach to assess the discriminatory capabilities of the RMTs. …”
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Identification of Clusters in a Population With Obesity Using Machine Learning: Secondary Analysis of The Maastricht Study by Maik JM Beuken, Melanie Kleynen, Susy Braun, Kees Van Berkel, Carla van der Kallen, Annemarie Koster, Hans Bosma, Tos TJM Berendschot, Alfons JHM Houben, Nicole Dukers-Muijrers, Joop P van den Bergh, Abraham A Kroon, Iris M Kanera

“…A significantly higher proportion (475/1149, 41.34%) in cluster 3 received higher vocational or university education in comparison to clusters 1 and 2 combined (729/2979, 24.47%; P<.001). …”
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The immune checkpoint molecule B7-H4 regulates β-cell mass and insulin secretion by modulating cholesterol metabolism through Stat5 signalling by Fangzhen Xia, Ziteng Zhang, Zhen Qian, Xiaoyu Fang, Junxue Wang, Yan Wang, Guoting Sun, Yuefeng Yu, Ninjian Wang, Junke Zhen, Yan Liu, Yingli Lu

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Eye Collateral Channel Characteristic Analysis and Identification Model Construction of Mild Cognitive Impairment by WU Tiecheng, CAO Lei, YIN Lianhua, HE Youze, LIU Zhizhen, YANG Minguang, XU Ying, WU Jinsong

“…Eligible subjects were matched on a 1∶1 propensity score according to sex, age, and years of education and were divided into MCI group and normal cognition group, with 158 cases in each group. …”
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Relationship between internet gaming disorder, interpersonal needs, loneliness, and depression among adolescents using a chain mediation model by GAO-QU Yige, MUZAI Baier, DONG Jingwen, ZHAO Yuxi, ZHU Pengyu, GU Xicheng, LIU Shangbin, CAI Yong, YUAN Dong, WANG Ying

“…The survey was conducted with a questionnaire consisting of general information (sex, age, grade, parents’ education level), the Chinese version of the IGDS9-SF, the INQ-15, the short-form of the ULS-8 and the PHQ-9 were used to evaluate the depression status of adolescents. …”
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Application of Baduanjin qigong exercise for community-based group of elderly individuals with chronic nonspecific low back pain (中医气功八段锦干预社区老年慢性非特异性下腰痛患者的效果分析)... by LI Juan (栗娟), BAI Jianying (白建英), LI Jie (李洁), SHEN Yongqing (沈永青), QI Suwen (戚素文), FENG Huiling (冯会玲)

“…The control group received routine care and health education about chronic nonspecific low back pain, and the experimental group received Baduanjin qigong exercise additionally. …”
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Epilog sau despre „cazul” Laurenţiu Fulga by Nina Arhip

“…Depuis octobre 1945 il est rédacteur à « Glasul Armatei » (« La Voix de l’Armée »), responsable de « l’éducation politique ». Malgré ses efforts de suivre la ligne politique, en septembre 1948 Laurenţiu Fulga est arrêté. …”
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The hypoxia adaptation strategy of the big-belly seahorses (Hippocampus abdominalis) with tuft gills by Long-Wu Jia, Le-Le Zhang, Hong-Wei Yang, Chun-Yu Hou, Lin Shi, Yu-Ping Hou, Guo-Dong Zheng, Xiao-Lei Su, Kai Wang

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Refined construction of semi-provincial hydrogeological models using hierarchical modeling: A case study in Western Shandong Province, China by Guangjun Ji, Zizhao Cai, Xiaobo Tan, Tao Wang, Chuanqi Wang, Qiuxiao Xu, Bo Zhou, Yang Cui

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Anticholinergic burden and behavioral and psychological symptoms in older patients with cognitive impairment by Sabrina Pistorio, Gianluca Scotto di Tella, Vittoria Canzanella, Raffaella Merenda, Gianluigi Cuomo, Paola Iacotucci, Vincenzo Carnovale, Leonardo Bencivenga, Maria Vargas, Annalaura Manes, Mauro Cataldi, Giuseppe Rengo, Giuseppe Rengo, Michela Zanetti, Grazia Daniela Femminella, Grazia Daniela Femminella

“…No statistically significant differences were found between the two groups in terms of demographics (age, sex) and anamnestic variables (education, marital status, family history of dementia, hypertension, diabetes, smoking, dyslipidemia, atrial fibrillation, coronary heart disease and use of alcohol). …”
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