Effectiveness of Single-Tablet Combination Therapy in Improving Adherence and Persistence and the Relation to Clinical and Economic Outcomes by Carly J. Paoli, Jörg Linder, Khushboo Gurjar, Deepika Thakur, Julie Wyckmans, Stacy Grieve

“…**Objectives:** We conducted a systematic literature review (SLR) to examine STCT-associated outcomes across 4 evidence domains: clinical trials, real-world evidence (RWE), health-related quality of life (HRQoL) studies, and economic evaluations. **Methods:** Four SLRs were conducted across the aforementioned domains. …”
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An Insurance Value Modeling Approach That Captures the Wider Value of a Novel Antimicrobial to Health Systems, Patients, and the Population by Mei S. Chan, Richard Holloway, Robert King, Rosie Polya, Rebecca Sloan, Jack C. Kowalik, Tom Ashfield, Luke S.P. Moore, Thomas Porter, Jonathan Pearson-Stuttard

“…**Background:** Traditional health economic evaluations of antimicrobials currently underestimate their value to wider society. …”
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Estimating the Health-Related Quality of Life Benefit of Prophylactic Treatment for COVID-19 in Immunocompromised People: A Multimethod Valuation Study by Katy Gallop, Rebekah Hall, Michael Watt, Daniel Squirrell, Neil Branscombe, Sofie Arnetop, Andrew Lloyd

“…**Objective:** To estimate the potential HRQoL and utility benefit of PrEP for prevention of COVID-19 in individuals with IC conditions who may not have an adequate response of full vaccination (and therefore are at “highest risk” of severe COVID-19) that can be used in future economic evaluations of preventative therapies against COVID-19. …”
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