The Impact of Electrophysiological Diversity on Pattern Completion in Lithium Nonresponsive Bipolar Disorder: A Computational Modeling Approach by Abraham Nunes, Selena Singh, Anouar Khayachi, Shani Stern, Thomas Trappenberg, Martin Alda

“…Excessive inhibition also induces pattern completion deficits by limiting the number of correctly active neurons during pattern retrieval. Conclusions Excitability variance in CA3 pyramidal cell–like neurons observed in lithium nonresponders may predict pattern completion deficits in these patients. …”
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