The Role of Reflection in Doctoral Education: An Integrative Review of Approaches to Supporting Well-Being and Developmental Growth by Kamilla Klefbeck

“…This paper offers practical insights and tools for integrating care-based strategies into doctoral supervision, providing a framework to enhance doctoral students’ well-being and adaptability while helping supervisors balance their dual roles.…”
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Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis by Di Fu, Xingyue Shu, Lin Yao, Ge Zhou, Mengzhen Ji, Ga Liao, Yunwo Zhu, Ling Zou

“…“Dental caries”, “Streptococcus mutans”, “Lactobacilli”, “Probiotics”, and “Children” have been commonly used as keywords.DiscussionBased on bibliometric analysis, this study reviews the relationship between lactobacilli and dental caries, emphasizing their dual roles. The detection rate of lactobacilli is closely associated with the incidence and severity of dental caries. …”
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Targeting uric acid: a promising intervention against oxidative stress and neuroinflammation in neurodegenerative diseases by Lin Xu, Chengwei Li, Tiantian Wan, Xinyi Sun, Xiaojie Lin, Dong Yan, Jianjun Li, Penghui Wei

“…This review consolidates recent advancements in understanding how UA exerts neuroprotective effects on neurodegenerative diseases and emphasizes the dual roles of UA in managing oxidative stress and neuroinflammation. …”
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Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

“…Here it is demonstrated that dynamic light scattering (DLS) is sensitive and effective at measuring variation in lipoprotein size distributions following oxidative damage caused by peroxidation and nitration—two common physiological processes that play dual roles in both normal and pathogenic states. We establish the utility of DLS in detecting subtle variations in lipoprotein size, including potential aggregation and fission events resulting from chemical modifications. …”
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The Role of Self-Efficacy and Religiosity in Determining Female Teachers' Resilience by Siti Marisa, Nurussakinah Daulay, Nefi Darmayanti, Noor Shakirah Mat Akhir

“…Resilience is a crucial element in helping teachers manage various pressures and demands stemming from dual roles as educators and homemakers. This study aims to examine the influence of self-efficacy and religiosity on resilience, as well as to test the moderating role of religiosity in the relationship between self-efficacy and resilience. …”
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Integrative bioinformatics and immunohistochemical analysis unravel the prognostic significance and immunological implication of LIMCH1 in breast cancer: a retrospective study by Xin Yu, Bei Li, Wenge Li, Jingping Yuan, Shengrong Sun, Juanjuan Li

“…Abstract The current mortality rates for breast cancer underscore the need for better prognostic tools; moreover, LIM and calponin homology domain 1 (LIMCH1), which is a protein with dual roles in cancer, is a promising candidate for investigation. …”
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Voltage and Current Balancing of a Faulty Photovoltaic System Connected to Cascaded H-Bridge Multilevel Inverter by Kamel Djermouni, Ali Berboucha, Salah Tamalouzt, Djamel Ziane

“…In addition, the presence of a battery storage system plays dual roles: firstly, compensating the power fluctuations due to nonuniform operating conditions between phases, and secondly, ensuring system power supply during periods of no sunlight exposure. …”
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Coupling of alternative splicing and alternative polyadenylation by Zhang Xueying, Liu Feiyan, Zhou Yu

“…Interestingly, some classical RBPs play dual roles in both splicing and 3′-end processing. Finally, we discuss how long-read sequencing technologies aid in understanding the coordination of AS-APA events and envision that these findings may potentially promote the development of new strategies for disease diagnosis and treatment.…”
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Dual Functions of Androgen Receptor Overexpression in Triple-Negative Breast Cancer: A Complex Prognostic Marker by Umay Kiraz, Emma Rewcastle, Silja K. Fykse, Ingrid Lundal, Einar G. Gudlaugsson, Ivar Skaland, Håvard Søiland, Jan P. A. Baak, Emiel A. M. Janssen

“…High AR-DIA correlated with lower grade (<i>p</i> = 0.014), and lower proliferation (<i>p</i> = 0.004) but also with larger tumors (<i>p</i> = 0.047), distant metastasis (<i>p</i> = 0.052), and lymph node (LN) positivity (<i>p</i> < 0.001), highlighting its dual roles. Multivariate analysis revealed interaction between LN status and AR-DIA (<i>p</i> < 0.001) as the strongest prognostic factor, followed by fibrotic focus (FF; <i>p</i> = 0.009), mitotic activity index (MAI; <i>p</i> = 0.018), and stromal tumor-infiltrating lymphocytes (sTILs; <i>p</i> = 0.041). …”
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Investigating the role of cathepsins in breast cancer progression: a Mendelian randomization study by Shengyi Zhou, Shengyi Zhou, Shengyi Zhou, Yizhou Sun, Yizhou Sun, Wenzhang Zha, Wenzhang Zha, Guangjun Zhou, Guangjun Zhou

“…Cathepsin Z can mediate the effects of PRX, CRY2, ADCY3, and PELATON on in situ breast cancer.DiscussionThese findings highlight the dual roles of cathepsins as potential risk and protective factors for breast cancer, underscoring their potential in diagnostic and therapeutic strategies.…”
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Modulating tumor-associated macrophages through CSF1R inhibition: a potential therapeutic strategy for HNSCC by Kaiting Chen, Xiaochen Li, Shuyi Dong, Yu Guo, Ziyin Luo, Shi-Min Zhuang, Jie Liu, Tianrun Liu, Jing Liao, Weiping Wen

“…Abstract Purpose Tumor-associated macrophages (TAMs) are pivotal immune cells within the tumor microenvironment (TME), exhibiting dual roles across various cancer types. Depending on the context, TAMs can either suppress tumor progression and weaken drug sensitivity or facilitate tumor growth and drive therapeutic resistance. …”
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Work-related burnout and its associated factors among kindergarten teachers: a multi-center cross-sectional study in Ethiopia by Anmut Endalkachew Bezie, Girum Tareke Zewude, Amensisa Hailu Tesfaye, Amensisa Hailu Tesfaye, Asmare Asrat Yirdaw, Alebachew Bitew Abie, Giziew Abere

“…Kindergarten teachers are at higher risk of work-related burnout compared to other teaching professionals, due to their dual roles as both caregivers and educators for young children. …”
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