Roles of Copper Transport Systems Members in Breast Cancer by Yichang Chen, Chen Li, Mengxin Li, Bing Han

“…In this study, we summarize the workflow of copper transport systems and the dual role of copper in cancer, highlighting the contributions of specific members of the copper transport system to breast cancer. …”
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A scoping review to examine health care professionals' experiences as family caregivers. by Kristina M Kokorelias, Nira Rittenberg, Orianna Scali, Suzanne Smith-Bayley, Monique A M Gignac, Gary Naglie, Jessica Sheirs, Jill I Cameron

“…Expectations also highlights the dual role of participants as both caregivers and healthcare professionals This complex interplay led to a theme related to personal consequences, including stress, guilt, and potential burnout, but also positive aspects of the dual roles. …”
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The crosstalk between senescence, tumor, and immunity: molecular mechanism and therapeutic opportunities by Zehua Wang, Chen Chen, Jiaoyu Ai, Yaping Gao, Lei Wang, Shurui Xia, Yongxu Jia, Yanru Qin

“…However, senescence is increasingly recognized as a contributing factor to tumor progression. This dual role necessitates a careful evaluation of the beneficial and detrimental aspects of senescence within the tumor microenvironment (TME). …”
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Expression and Regulation of Hypoxia-Inducible Factor Signalling in Acute Lung Inflammation by Nikolaos S. Lotsios, Chrysi Keskinidou, Sotirios P. Karagiannis, Kostas A. Papavassiliou, Athanasios G. Papavassiliou, Anastasia Kotanidou, Ioanna Dimopoulou, Stylianos E. Orfanos, Alice G. Vassiliou

“…We explore the potential dual role of HIF signalling in acute lung inflammation. …”
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Green guardians: Bacterial endophytes in protecting vegetable crops against pathogens by Sagarika Medari, Krishnan Kalpana, Muthusamy Ramakrishnan, Aravindaram Kandan, Subbiah Ramasamy, Karuppiah Eraivan Arutkani Aiyanathan, Sankarasubramanian Harish, Andithevar Beaulah, Rangaswamy Anandham, Narayanan Manikandaboopathi, Marimuthu Ayyandurai

“…Importantly, bacterial endophytes play a dual role by safeguarding their plant host through the biocontrol of pathogens and induction of the plant's innate immune system. …”
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How environmental patents, education, and energy transition impact greenhouse gases: evidence from E7 countries by Bing Zhang, Yujing Wang, Mingyang Liu, Usman Mehmood, Usman Mehmood

“…These findings emphasize the need for targeted policies that leverage ENT and ENP for emissions reduction, strategically direct FD toward sustainable investments, and manage the dual role of EDU in emissions dynamics. This study offers critical insights for policymakers in the E−7 nations to balance economic growth with environmental sustainability, contributing to global efforts to combat climate change.…”
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The role of inflammasomes in hepatocellular carcinoma: Mechanisms and therapeutic insights by Valentina Arrè, Roberto Negro, Gianluigi Giannelli

“…Among others, the inflammasome Nucleotide-binding oligomerization domain, Leucine rich Repeat (NLR) and Pyrin (NLRP) 3 (NLRP3), and absent in melanoma 2 (AIM2), exhibit a dual role in HCC background. It has been reported that they can exert oncosuppressive functions by triggering the inflammatory death of cancer cells. …”
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The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD by Yan K, Wang Y, Xin P

“…Kunrong Yan, Yingjian Wang, Peng Xin Department of Anaesthesia, Chaoyang Second Hospital, Chaoyang, Liaoning, People’s Republic of ChinaCorrespondence: Peng Xin, Email cy08xp@163.comObjective: Observational studies have indicated that immune cells and circulating inflammatory proteins may play a dual role in the progression of COPD; however, the precise mechanisms remain uncertain. …”
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Proline and ROS: A Unified Mechanism in Plant Development and Stress Response? by Marco Renzetti, Dietmar Funck, Maurizio Trovato

“…This review uniquely integrates recent findings on the dual role of proline in both ROS scavenging and signaling, provides an updated overview of the most recent research published to date, and proposes a unified mechanism that could account for many of the multiple roles assigned to proline in plant development and stress defense. …”
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Mast cells: key players in digestive system tumors and their interactions with immune cells by Feihong Shu, Jie Yu, Youjia Liu, Fang Wang, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Yanxia Hu, Qian Du, Jingyu Xu, Rui Xie

“…Specifically, mast cells not only secrete mediators related to pro-tumor function such as trypsin-like enzymes, chymotrypsin, vascular endothelial cell growth factor and histamine, but also mediators related to anti-tumor progression such as cystatin C and IL-17F. This dual role of mast cells renders them an under-recognized but very promising target for tumor immunotherapy. …”
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A mixed methods exploration of self-presentation, authenticity, and role model function on Instagram: perspectives from female influencers in Germany by Daniel Zimmermann, Colleen Schneider, Kai Kaspar

“…Influencers find themselves in a dual role as users and producers. This results in concrete behavioral challenges for them, but also in implications for established theories of media use.…”
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Self‐Healing COCu‐Tac Hydrogel Enhances iNSCs Transplantation for Spinal Cord Injury by Promoting Mitophagy via the FKBP52/AKT Pathway by Zhenming Tian, Han‐Jian Hu, Chun Cheung Chan, Tian Hu, Chaoyang Cai, Hong Li, Limin Rong, Gang‐Biao Jiang, Bin Liu

“…Tacrolimus, known for its dual role as an immunosuppressant and promoter of neural regeneration, holds the potential for enhancing iNSC transplantation. …”
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Proinflammatory Responses of Heme in Alveolar Macrophages: Repercussion in Lung Hemorrhagic Episodes by Rafael L. Simões, Maria Augusta Arruda, Cláudio Canetti, Carlos H. Serezani, Iolanda M. Fierro, Christina Barja-Fidalgo

“…Taken together, the data support a dual role for heme in the inflammatory response associated with lung hemorrhage, acting as a proinflammatory molecule that can either act as both an adjuvant of the innate immunity and as an amplifier of the inflammatory response, leading tissue injury. …”
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Numerical simulation of rotating flow of CNT nanofluids with thermal radiation, ohmic heating, and autocatalytic chemical reactions by S. Eswaramoorthi, Saleem Nasir, K. Loganathan, M. Satyanarayana Gupta, Abdallah Berrouk

“…The magnetic field parameter and the Forchheimer number play a dual role in both directional skin friction coefficients. …”
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Targeting autophagy to enhance chemotherapy and immunotherapy in oral cancer by Xiaoli Zeng, Xiaoli Zeng, Xiaoli Zeng, Yue Chen, Yue Chen, Jing Wang, Jing Wang, Miao He, Miao He, Junyao Qiu, Yun Huang

“…Autophagy, a catabolic process induced under stress conditions, has been shown to play a dual role in oral cancer development and therapy. Recent studies have identified that autophagy activation in oral epithelial cells suppresses cancer cell survival by inhibiting key pathways such as the mammalian target of rapamycin (mTOR) and mitogen-activated protein kinase (MAPK), while activating the adenosine monophosphate-activated protein kinase (AMPK) pathway. …”
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Exploring the Molecular Modalities in the Pathogenesis of Diabetic Kidney Disease with a Focus on the Potential Therapeutic Implications by Lyubomir Gaydarski, Kristina Petrova, Ivan Angushev, Stancho Stanchev, Alexandar Iliev, Nikola Stamenov, Vidin Kirkov, Boycho Landzhov

“…Preclinical studies highlight its dual role in renal protection and injury through anti-inflammatory and antioxidant pathways, while other evidence suggests that it may exacerbate DKD through podocyte damage and angiogenesis. …”
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Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease by Hourolein Arab, Mohammad Reza Mofid, Mahboube Rahmati, Elahe Gharehkhani, Armin Mokhtariye, Mohammad Shokrzadeh

“…Recent studies have highlighted the dual role of autophagy in cancer: while it can act as a tumor suppressor in early stages, it may also support tumor cell survival in advanced stages. …”
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The genomes of Scedosporium between environmental challenges and opportunism by Francesco Venice, Federica Spina, Domenico Davolos, Stefano Ghignone, Giovanna Cristina Varese

“…By contrast, several features in Microascaceae and Scedosporium were detected that might have a dual role in responding to environmental challenges and allowing colonization of the human body, including chitin, melanin and other cell wall related genes, proteases, glutaredoxins and magnesium transporters. …”
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Multi-omic and machine learning analysis of mitochondrial RNA modification genes in lung adenocarcinoma for prognostic and therapeutic implications by Xiao Zhang, Jiatao Liu, Yaolin Cao, Wei Wang, Haoran Lin, Yue Yu

“…In conclusion, this study establishes MRMS as a robust prognostic biomarker and highlights its dual role in shaping the tumor immune microenvironment and guiding therapeutic strategies. …”
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The eradication of pea weevil Bruchus pisorum (L.) (Coleoptera: Chrysomelidae) from New Zealand by David G. Voice, Rory MacLellan, Adrian Russell, Dave Goulden, Ivan Lawrie, Greg Baker, David A. J. Teulon, John M. Kean

“…Trap crops played a dual role for local surveillance and beetle destruction. …”
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