Tuberculosis and drug resistance in a region of Southern Italy among native and foreign-born populations: A twelve-year province-based study by Salvatore Rotundo, Salvatore Nisticò, Helen Linda Morrone, Luigia Gallo, Saveria Dodaro, Carmelo Papola, Pasquale Minchella, Giovanni Matera, Francesca Greco, Luigi Principe, Lorenzo Antonio Surace, Francesco Lucia, Francesca Serapide, Alessandro Russo, Carlo Torti, Enrico Maria Trecarichi

“…Among these strains, 20 (74.1 %) were isoniazid-resistant (MDR-TB).This study underscores the need for comprehensive TB control strategies, especially regarding co-infection with HIV and the emergence of drug-resistant strains, emphasizing the importance of early detection and tailored management in Southern Italy.…”
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Analysis of the genome data of Acinetobacter baumannii UOL-KIMZ-24, exhibiting multiple drug resistance through efflux pumpsGenebANK/NCBI. by Kiran Fatima, Syed Zeeshan Haider Naqvi, Hazrat Ali, Noor Hassan, Anam Saqib, Farheen Ansari, Sidrah Saleem, Shah Jahan, Mushtaq Ahmad

“…During the initial screening for antimicrobial susceptibility, the UOL-KIMZ-24 was found a multiple drug resistant (MDR) strain. However, the detailed genomic insights for genes e.g. responsible for exhibiting antibiotic resistance via efflux pumps, have not yet been reported from A. baumannii strains, recovered from LGH. …”
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Real-world clinical multi-omics analyses reveal bifurcation of ER-independent and ER-dependent drug resistance to CDK4/6 inhibitors by Zhengyan Kan, Ji Wen, Vinicius Bonato, Jennifer Webster, Wenjing Yang, Vladimir Ivanov, Kimberly Hyunjung Kim, Whijae Roh, Chaoting Liu, Xinmeng Jasmine Mu, Jennifer Lapira-Miller, Jon Oyer, Todd VanArsdale, Paul A. Rejto, Jadwiga Bienkowska

“…Abstract To better understand drug resistance mechanisms to CDK4/6 inhibitors and inform precision medicine, we analyze real-world multi-omics data from 400 HR+/HER2- metastatic breast cancer patients treated with CDK4/6 inhibitors plus endocrine therapies, including 200 pre-treatment and 227 post-progression samples. …”
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Enhanced bacteriostatic effects of phage vB_C4 and cell wall-targeting antibiotic combinations against drug-resistant Aeromonas veronii by Xin Cao, Yanqiong Tang, ZhenZhang Lu, Xiang Ma, Hong Li, Xue Chi, Juanjuan Li, Zhu Liu

“…ABSTRACT Aeromonas veronii is a vital zoonotic pathogen known for its extensive drug resistance and ability to form biofilms, which contribute to its antibiotic resistance. …”
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Molecular Epidemiology, Drug-Resistant Variants, and Therapeutic Implications of Hepatitis B Virus and Hepatitis D Virus Prevalence in Nigeria: A National Study by Oludare ‘Sunbo Adewuyi, Muhammad Shakir Balogun, Hirono Otomaru, Alash’le Abimiku, Anthony Agbakizu Ahumibe, Elsie Ilori, Que Anh Luong, Nwando Mba, James Christopher Avong, John Olaide, Oyeladun Okunromade, Adama Ahmad, Afolabi Akinpelu, Chinwe Lucia Ochu, Babatunde Olajumoke, Haruka Abe, Chikwe Ihekweazu, Adetifa Ifedayo, Michiko Toizumi, Hiroyuki Moriuchi, Katsunori Yanagihara, Jide Idris, Lay-Myint Yoshida

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Biological Characteristics and Whole Genome Analysis of vB_VpP_3, a Bacteriophage against Multi-drug Resistant Vibrio parahaemolyticus by LIU Qingqing, ZHANG Ming, YANG Wenjing, LIU Ke, LI Fan, LI Xuepeng, LI Jianrong, ZHANG Defu

“…Its genome was double-stranded linear DNA with a total length of 42 459 bp and a total GC content of 46.87% without any virulence or drug resistance genes. Conclusion: Bacteriophage vB_VpP_3 was highly safe and could be used for biological control of multi-drug resistant V. parahaemolyticus.…”
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Impact of alcohol drinking and tobacco smoking on the drug-resistance of newly diagnosed tuberculosis: a retrospective cohort study in Shandong, China, during 2004–2020 by Yi-Fan Li, Yao Liu, Qi Fu, Wan-mei Song, Jin-yue Liu, Qian-yun Zhang, Ting-ting Xu, Shi-jin Li, Qi-qi An, Si-qi Liu, Huai-chen Li, Ning Ning Tao, Xue-han Zhu, Chun-bao Yu, Jihua Dong

“…However, there were no significant differences between G1 and G0, G2 and G0 in all drug-resistant subtypes. Those patients with cavity had a higher risk of DR-TB among G3 (OR=1.35, 95% CI: 1.01 to 1.81).Conclusion Although we did not found an independent impact of alcohol drinking or tobacco smoking on TB drug-resistance, respectively, these two habits had a combined effect on TB drug-resistance.…”
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Prevalensi Kuman Multi Drug Resistance (MDR) di Laboratorium Mikrobiologi RSUP Dr. M. Djamil Padang Periode Januari 2010 - Desember 2012 by Novilla Rezka Sjahjadi, Roslaili Rasyid, Erlina Rustam, Lily Restusari

“…<p>Abstrak<br />Kuman Multi Drug Resistance (MDR) menyebabkan semakin sulit dalam memilih antibiotika untuk pasien yang mengalami infeksi. …”
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The impact of the COVID-19 pandemic on TB notifications in Ukraine in 2020 by A.N. Shapiro, M. Dolynska, S.S. Chiang, N. Rybak, V. Petrenko, C.R. Horsburgh Jr, J. Kobe, I. Terleieva, O. Sakalska, H.E. Jenkins

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Diagnostic and Therapeutic Advances of RNAs in Precision Medicine of Gastrointestinal Tumors by Runhan Liu, Jiaxin Zhou, Xiaochen Chen, Jie Zhang, Qunzhi Chen, Xiaoming Liu, Kunhou Yao

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Advances in the relationship between AP-1 and tumorigenesis, development and therapy resistance by Xinni Xue, Zhiwei Li, Jiahui Zhao, Ziyi Zhao, Zhihang Li, Yong Li, Yawen Liu, Huan He

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Exploring northeast India’s culturable soil Actinomycetia for potent antibacterial agents against gram-positive bacterial pathogens of clinical importance by Aditya Narayan Konwar, Surajit Basak, Shalini Gurumayum, Jagat Chandra Borah, Debajit Thakur

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Molecular characterization of putative antibiotic resistance determinant and virulence factors genes of Acinetobacter baumannii strains isolated from intensive care unit patients i... by Faris A. Alanazi, Khalid S. Almaary, Turki M. Dawoud, Mohamed A. El-Tayeb, Yahya B. Elbadawi, Ayman S. Mubarak, Ali M. Somily

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The Evolution of Antimicrobial Resistance in <i>Acinetobacter baumannii</i> and New Strategies to Fight It by Viola Camilla Scoffone, Gabriele Trespidi, Giulia Barbieri, Arooba Arshad, Aygun Israyilova, Silvia Buroni

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ABA enhances the apoptotic effect of docetaxel in the multidrug-resistant DU145 prostate cancer cell line by Şumnulu Deniz, Doğanlar Zeynep Banu

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Theoretical assessment of the relative incidences of sensitive andresistant tuberculosis epidemic in presence of drug treatment by Silvia Martorano Raimundo, Hyun Mo Yang, Ezio Venturino

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Understanding Rifampicin Resistance in Tuberculosis through a Computational Approach by Satish Kumar, Lingaraja Jena

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Cupriavidus gilardii infection following heart failure: a case report and literature review by Yanwen Liu, Jianxin Gao, Jingyun Ye, Hui Han, Haiyan Zhu

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Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama by Ximena Norero, Dora Estripeaut, Elizabeth Castaño, Jacqueline Levy, Paola Lichtenberger, José Pablo Díaz-Madriz, José Luis Bustos, Robin Rojas Cortés, Gabriel Levy-Hara

Subjects: “…drug resistance, microbial…”
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Structural characteristics, functions, and counteracting strategies of biofilms in Staphylococcus aureus by Yanze Xia, Zhenghui Hu, Qiyuan Jin, Qi Chen, Chenhao Zhao, Rui Qiang, Zonggang Xie, Liubing Li, Haifang Zhang

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